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Nutrition: Sodium Chloride

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Stroke: What is a healthy amount of salt? This is the maximum you should eat
STROKE is a dangerous condition which causes some brain cells to die. To avoid it you can make diet changes to remove substances that increase your risk, such as salt which raises blood pressure. However you still need some salt, or sodium, to function normally. You should eat this much salt to help control the condition.
Source: Daily Express - Health - June 13, 2018 Category: Consumer Health News Source Type: news

Stroke: What is a good amount of salt? This is how much you can eat
STROKE is a dangerous condition which causes some brain cells to die. To avoid it you can make diet changes to remove substances that increase your risk, such as salt which raises blood pressure. However you still need some salt, or sodium, to function normally. You should eat this much salt to help control the condition.
Source: Daily Express - Health - June 13, 2018 Category: Consumer Health News Source Type: news

High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke
In this study, whe...
Source: Journal of Neuroinflammation - April 12, 2021 Category: Neurology Authors: Mengyan Hu, Yinyao Lin, Xuejiao Men, Shisi Wang, Xiaobo Sun, Qiang Zhu, Danli Lu, Sanxin Liu, Bingjun Zhang, Wei Cai and Zhengqi Lu Tags: Research Source Type: research

Preeclampsia Linked to Increased Stroke Risk in Later Life
TUESDAY, April 27, 2021 -- Preeclampsia seems to be associated with an increased risk for stroke in later life, according to a study published online April 26 in JAMA Network Open. Adam de Havenon, M.D., from the University of Utah in Salt Lake...
Source: Drugs.com - Pharma News - April 27, 2021 Category: Pharmaceuticals Source Type: news

547 quality improvement project in prescribing thickeners post stroke
ConclusionThis project has built up a multidisciplinary system to a multidisciplinary problem. Through repeated cycles and system improvement, we have seen and demonstrated a collaborative effort resulting in consistent and improving results.
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

Thromboxane A < sub > 2 < /sub > receptor antagonist (ONO-8809) attenuates renal disorders caused by salt overload in stroke-prone spontaneously hypertensive rats
In this study, we focused on evaluating the histological and gene expression effects in the kidneys of stroke-prone spontaneously hypertensive rats (SHRSP) with a high salt intake and the thromboxane A2 / prostaglandin H2 receptor (TPR) blocker ONO-8809. Six-week-old SHRSPs aged 6 weeks, were divided into three groups and were fed normal chow containing 0.4% NaCl, 2.0%NaCl, or 2.0%NaCl +ONO-8809 (0.6 mg/kg p.o. daily). Histological analyses with immunohistochemistry and a gene expression assay with a DNA kidney microarray were performed after eight weeks. The following changes were observed in SHRSPs with the high salt int...
Source: Clinical and Experimental Pharmacology and Physiology - June 21, 2021 Category: Drugs & Pharmacology Authors: Yusuke Nagatani Toshihide Higashino Kosho Kinoshita Hideaki Higashino Source Type: research

Role of no table salt on hypertension and stroke based on large sample size from National Health and Nutrition Examination Survey database
To assess the associations between no table salt and hypertension or stroke.
Source: BMC Public Health - July 5, 2022 Category: Consumer Health News Authors: Zongqin Li, Lan Hu, Xiaoxia Rong, Jun Luo, Xuejie Xu and Yonglong Zhao Tags: Research Source Type: research

Could salt intake directly affect the cerebral microvasculature in hypertension?
Cerebral small vessel disease (CSVD) is a significant cause of stroke and dementia,1,2 as well as gait impairment and falls in the elderly.3 However, its pathophysiology is still poorly understood, and no specific treatment strategies exist.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2022 Category: Neurology Authors: Ana Monteiro, Pedro Castro, Gilberto Pereira, Carmen Ferreira, Cristina Duque, Farzaneh Sorond, Andrew Milstead, James P. Higgins, Jorge Pol ónia, Elsa Azevedo Source Type: research

'Significant impact': Pharmacist warns 'soluble' tablets can increase risk of stroke
The warning comes after a study involving 300,000 participants found salt in soluble paracetamol increased risk of heart attacks, stroke, heart failure and death.
Source: Daily Express - Health - October 9, 2022 Category: Consumer Health News Source Type: news

Effectiveness of butylphthalide on cerebral autoregulation in ischemic stroke patients with large artery atherosclerosis (EBCAS study): A randomized, controlled, multicenter trial
J Cereb Blood Flow Metab. 2023 Apr 6:271678X231168507. doi: 10.1177/0271678X231168507. Online ahead of print.ABSTRACTFinding appropriate drugs to improve cerebral autoregulation (CA) in patients with acute ischemic stroke (AIS) is necessary to improve prognosis. We aimed to investigate the effect of butylphthalide on CA in patients with AIS. In this randomized controlled trial, 99 patients were 2:1 randomized to butylphthalide or placebo group. The butylphthalide group received intravenous infusion with a preconfigured butylphthalide-sodium chloride solution for 14 days and an oral butylphthalide capsule for additional 76 ...
Source: Atherosclerosis - April 6, 2023 Category: Cardiology Authors: Zhen-Ni Guo Bing-Hong Yue Lei Fan Jie Liu Yuanyuan Zhu Yuanqi Zhao Jingxin Zhong Zhan Lou Xing-Liang Liu Reziya Abuduxukuer Peng Zhang Yang Qu Ziduo Shen Baoyang Shi Ke-Jia Zhang Jia Liu Junlei Chang Hang Jin Xin Sun Yi Yang Source Type: research

Potential Applications of Remote Limb Ischemic Conditioning for Chronic Cerebral Circulation Insufficiency
Conclusion Due to its long-term and often invisible course, CCCI has received less attention than acute cerebral ischemic stroke. However, without appropriate intervention, CCCI may lead to a variety of adverse events. Because the pathophysiological changes associated with CCCI are complex, pharmacological research in this area has been disappointing. Recent research suggests that RLIC, which is less invasive and more well-tolerated than drug treatment, can activate endogenous protective mechanisms during CCCI. In the present report, we reviewed studies related to CCCI (Table 1), as well as those related to stroke and sta...
Source: Frontiers in Neurology - May 2, 2019 Category: Neurology Source Type: research

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin. Ethics Statement This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Long-term Fine Particulate Matter Exposure and Nonaccidental and Cause-specific Mortality in a Large National Cohort of Chinese Men
Conclusions: Long-term exposure to PM2.5 was associated with nonaccidental, CVD, lung cancer, and COPD mortality in China. The IER estimator may underestimate the excess relative risk of cause-specific mortality due to long-term exposure to PM2.5 over the exposure range experienced in China and other low- and middle-income countries. https://doi.org/10.1289/EHP1673 Received: 24 February 2017 Revised: 01 September 2017 Accepted: 05 September 2017 Published: 07 November 2017 Address correspondence to M. Zhou, National Center for Chronic Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control ...
Source: EHP Research - November 7, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research