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Total 43 results found since Jan 2013.

QTc prolongation as a possible contributor to Stroke
Some antipsychotics have been associated with increased risk for stroke (1). As demonstrated by the REGARDS Study (Reasons for Geographic and Racial Differences in Stroke), a prolonged QTc interval is associated with an increased risk of stroke (3). Antipsychotic agents, known to cause prolongation of the QTc, may increase the risk of stroke in a geriatric population.
Source: The American Journal of Geriatric Psychiatry - September 12, 2021 Category: Geriatrics Authors: Dr Poonam Awatramani, Dr Rosemary V Busch Conn, H Mytrang Tags: Letter to the Editor Source Type: research

Baseline Risk of Metabolic Syndrome Among Participants Post Stroke Enrolled in an Intensive Lifestyle Intervention to Promote Weight-Loss
To describe the (1) weight and medical history and (2) physical activity and eating behaviors of participants post stroke enrolled in a 12-month intensive lifestyle intervention.
Source: Archives of Physical Medicine and Rehabilitation - March 31, 2021 Category: Rehabilitation Authors: Simon Driver, Chad Swank, Katherine Froehlich-Grobe, Evan Elizabeth McShan, Stephanie Calhoun, Sharon Brown, Noelia Ramirez, Monica Bennett, Librada Callender, Danielle Miro, Rosemary Dubiel, Sridevi Mukkamala Tags: Late Breaking Research Papers Posters Source Type: research

Off-Pump Coronary Artery Bypass Reduces Cardiac Death in Patients with Peripheral Arteriopathy
Conclusions The OPCAB procedure considerably reduced the occurrence of cardiac death after coronary revascularization. This finding might suggest that the OPCAB procedure should be considered as the first option in patients with higher cardiovascular risk scores. Further research is warranted. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: The Thoracic and Cardiovascular Surgeon - February 24, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Bonacchi, Massimo Howe, Rosemary Micali, Linda Renata Weigel, Daniel Parise, Orlando Parise, Gianmarco Gelsomino, Sandro Tags: Original Cardiovascular Source Type: research

Process evaluation of an implementation trial to improve the triage, treatment and transfer of stroke patients in emergency departments (T3 trial): a qualitative study
The implementation of evidence-based protocols for stroke management in the emergency department (ED) for the appropriate triage, administration of tissue plasminogen activator to eligible patients, management...
Source: Implementation Science - November 4, 2020 Category: Health Management Authors: Elizabeth McInnes, Simeon Dale, Louise Craig, Rosemary Phillips, Oyebola Fasugba, Verena Schadewaldt, N. Wah Cheung, Dominique A. Cadilhac, Jeremy M. Grimshaw, Chris Levi, Julie Considine, Patrick McElduff, Richard Gerraty, Mark Fitzgerald, Jeanette Ward, Tags: Research Source Type: research

Cancers, Vol. 12, Pages 1285: Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children
Conclusion: This represents the largest GWAS meta-analysis conducted to date associating SNPs to VTE in children and adolescents treated on childhood ALL protocols. Validation of these findings is needed and may then lead to patient stratification for VTE preventive interventions. As VTE hemostasis involves multiple pathways, a more powerful GWAS is needed to detect combination of variants associated with VTE.
Source: Cancers - May 18, 2020 Category: Cancer & Oncology Authors: Marion K. Mateos Morten Tulstrup Michael CJ Quinn Ruta Tuckuviene Glenn M. Marshall Ramneek Gupta Chelsea Mayoh Benjamin O. Wolthers Pasquale M. Barbaro Ellen Ruud Rosemary Sutton Pasi Huttunen Tamas Revesz Sonata S. Trakymiene Draga Barbaric Ulf Tedg år Tags: Article Source Type: research

Antithrombotic activity of flavonoids and polyphenols rich plant species.
Abstract Cardiovascular diseases represent one of the most notable health problems of the modern civilization. Stroke and heart attack often lead to lethal outcome; essential problem underneath being thrombus formation. Prophylactic approaches include acetylsalicylic acid and clopidogrel therapy on the level of primary hemostasis, i.e., primary clot formation. In the last five years, in the USA, health care expenses related to cardiovascular diseases have increased 50 %, to over 350 billion dollars. Thus, application of plant species and medicinal plants rich in polyphenols in prevention of thrombus formation are ...
Source: Acta Pharmaceutica - October 23, 2019 Category: Drugs & Pharmacology Authors: Bojić M, Maleš Ž, Antolić A, Babić I, Tomičić M Tags: Acta Pharm Source Type: research

Timing of Direct Enteral Tube Placement and Outcomes after Acute Stroke
Background: Direct enteral feeding tube (DET) placement for dysphagia after stroke is associated with poor outcomes. However, the relationship between timing of DET placement and poststroke mortality and disability is unknown. We sought to determine the risk of mortality and severe disability in patients who receive DET at different times after stroke. Methods: We used the Ontario Stroke Registry and linked administrative databases to identify patients with acute ischemic stroke or intracerebral hemorrhage between 2003 and 2013 who received DET (gastrostomy or jejunostomy) during their hospital admission.
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2019 Category: Neurology Authors: Raed A. Joundi, Gustavo Saposnik, Rosemary Martino, Jiming Fang, Moira K. Kapral Source Type: research

Can an Ankle Foot Orthoses with a Heel Lift Decrease Genu Recurvatum in Adults Post-Stroke?
Genu recurvatum (GR) in persons who are post-stroke can lead to excessive peak knee extension (>5 degrees) during the stance phase of gait. If untreated, GR can contribute to knee instability, weakness, osteoarthritis, and chronic pain. The purpose of this study was to investigate the effect of combining a heel lift with an ankle-foot orthosis (AFO) on genu recurvatum during gait in persons who are post-stroke. We hypothesized that the heel lift would result in a decrease in peak knee extension during the stance phase of gait.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Courtney Whyte, Alexandros Savva, Nadia Zaman, Calvin Chen, Chory Ashley, William Werner, Ona Bloom, Anthony Oreste, Rosemary Gallagher Source Type: research

Carotid artery plaque detected on ultrasound is associated with impaired cognitive state in the elderly: A population-based study in Wakiso district, Uganda
This study set out to determine the prevalence of abnormal carotid ultrasound findings and their association with cognitive function among the adults ≥60 years in Wakiso district, Uganda in 2018. A total of 210 participants were included. Carotid artery stenosis, presence of plaque, stenosis and intima-media thickness were assessed by ultrasound. Cognitive status was assessed using a Mini Mental State Exam (MMSE) test. The prevalence of plaque was 21.4%. Variables which included; presence of plaque, age, education, gender, marital status, whether participant stayed alone or with someone else, care for self, occupation ...
Source: Journal of Clinical Neuroscience - July 12, 2019 Category: Neuroscience Source Type: research

Palm oil and dietary change: Application of an integrated macroeconomic, environmental, demographic, and health modelling framework for Thailand
Publication date: Available online 18 January 2019Source: Food PolicyAuthor(s): Henning Tarp Jensen, Marcus R. Keogh-Brown, Bhavani Shankar, Wichai Aekplakorn, Sanjay Basu, Soledad Cuevas, Alan D. Dangour, Shabbir H. Gheewala, Rosemary Green, Edward J.M. Joy, Nipa Rojroongwasinkul, Nalitra Thaiprasert, Richard D. SmithAbstractPalm oil is a cooking oil and food ingredient in widespread use in the global food system. However, as a highly saturated fat, palm oil consumption has been associated with negative effects on cardiovascular health, while large scale oil palm production has been linked to deforestation. We construct a...
Source: Food Policy - January 20, 2019 Category: Food Science Source Type: research

Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial
Publication date: Available online 5 December 2018Source: The LancetAuthor(s): Martin Dennis, Gillian Mead, John Forbes, Catriona Graham, Maree Hackett, Graeme J Hankey, Allan House, Stephanie Lewis, Erik Lundström, Peter Sandercock, Karen Innes, Carol Williams, Jonathan Drever, Aileen Mcgrath, Ann Deary, Ruth Fraser, Rosemary Anderson, Pauli Walker, David Perry, Connor McgillSummaryBackgroundResults of small trials indicate that fluoxetine might improve functional outcomes after stroke. The FOCUS trial aimed to provide a precise estimate of these effects.MethodsFOCUS was a pragmatic, multicentre, parallel group, double-b...
Source: The Lancet - December 5, 2018 Category: General Medicine Source Type: research

Feeding and swallowing impairment in children with stroke and unilateral cerebral palsy: a systematic review
AimThis systematic review targeted frequency estimates of dysphagia (feeding and swallowing problems), related health outcomes, and caregiver burden in children with stroke or unilateral cerebral palsy (CP).MethodSix electronic databases were searched from their inception to November 2017 along with a manual search of eight relevant journals. Two blinded raters assessed abstracts and full articles for eligibility. Discrepancies were resolved by consensus. Accepted articles were evaluated for quality. Data were extracted and analysed descriptively.ResultsOf 1660 abstracts, five met inclusion criteria, of which three focused...
Source: Developmental Medicine and Child Neurology - November 9, 2018 Category: Child Development Authors: Victoria Sherman, Elissa Greco, Mahendranath Moharir, Deryk Beal, Kevin Thorpe, Rosemary Martino Tags: Systematic Review Source Type: research

Predictors of Direct Enteral Tube Placement After Acute Stroke
To determine predictors of direct enteral tube (DET) placement after acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2018 Category: Neurology Authors: Raed A. Joundi, Gustavo Saposnik, Rosemary Martino, Jiming Fang, Moira K. Kapral Source Type: research

Neutrophil-to-lymphocyte ratio predicts heart failure readmissions and outcomes in patients undergoing transcatheter aortic valve replacement
ConclusionNLR predicts all-cause mortality, MACE, and HF hospitalization 1 year after TAVR. NLR with TAVR risk score improved predictability for MACE. Further studies for prognostication using NLR are warranted.
Source: Indian Heart Journal - September 14, 2018 Category: Cardiology Source Type: research

Effects of Riociguat on Right Ventricular Remodelling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study
ConclusionsRiociguat treatment was associated with increased RV stroke volume index and trends for improvement in myocardial remodelling in patients with CTEPH. A larger clinical study is warranted to observe the therapeutic benefits of riociguat on RV remodelling.RésuméContexteLes effets du traitement par le riociguat sur le métabolisme, la perfusion et le débit du ventricule droit (VD) chez les patients atteints d’hypertension pulmonaire thromboembolique chronique (HPTC) sont inconnus. Dans la présente étude, nous analysons les changements aux ventriculaires droits associés au traitement par le riociguat.Méthod...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research