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Risk of stroke following antivenom use after venomous snakebite: correspondence
We read with great interest the epidemiological study by Hunget al.1 on the risk of stroke with antivenom use after venomous snakebite in Taiwan. According to the national medical claims data, the authors provide us with useful information and disclose that venomous snakebite is associated with an increased risk of hemorrhagic stroke after the use of antivenom after using the matching propensity score in relevant measurable covariates. We strongly agree with the comments by Yehet al.2 on the unmeasured confounders associated with stroke in the present study. Furthermore, we are concerned that other residual confounders rel...
Source: QJM - April 26, 2023 Category: Internal Medicine Source Type: research

Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters. [time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
AbstractPurpose of ReviewStroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and anticoagulants in secondary prevention of acute ischemic stroke and transient ischemic attack (TIA), ...
Source: Current Neurology and Neuroscience Reports - April 11, 2023 Category: Neuroscience Source Type: research

High-Salt Diet a Danger Even With Normal Blood Pressure
A large study shows eating a diet high in salt is linked to clogged arteries of the heart and neck, raising the risk of heart attack and stroke, even in people with normal blood pressure.
Source: WebMD Health - April 10, 2023 Category: Consumer Health News Source Type: news

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
Curr Neurol Neurosci Rep. 2023 Apr 11. doi: 10.1007/s11910-023-01266-2. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Stroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and antic...
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Kunal Bhatia Lindsey M Ladd Kelsey H Carr Mario Di Napoli Jeffrey L Saver Louise D McCullough Maryam Hosseini Farahabadi Diana L Alsbrook Archana Hinduja Jorge G Ortiz Garcia Sara Y Sabbagh Alibay Jafarli Afshin A Divani Source Type: research

Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during the development of obesity
by Taylor McFadden, Natasha Gaito, Isabella Carucci, Everett Fletchall, Kayla Farrell, Timothy J. Jarome Obesity is a complex medical condition that is linked to various health complications such as infertility, stroke, and osteoarthritis. Understanding the neurobiology of obesity is crucial for responding to the etiology of this disease. The hypothalamus coordinates many integral activities such as hormone regulation and feed intake and numerous studies have observed altered hypothalamic gene regulation in obesity models. Previously, it was reported that the promoter region of the satiety gene,Pomc, has increased DNA met...
Source: PLoS One - April 10, 2023 Category: Biomedical Science Authors: Taylor McFadden Source Type: research

Lifestyle-related habits and factors before and after cardiovascular diagnosis: a case control study among 2,548 Swedish individuals
CONCLUSION: The results indicate that a CVD event may increase motivation to improve lifestyle habits. Nonetheless, the prevalence of unhealthy lifestyle habits was still high, emphasizing the need to improve implementation of primary and secondary CVD prevention.PMID:37020317 | DOI:10.1186/s12966-023-01446-w
Source: Health Physics - April 5, 2023 Category: Physics Authors: Amanda L önn Lena V Kallings Gunnar Andersson Sofia Paulsson Peter Wallin Jane Salier Eriksson Elin Ekblom-Bak Source Type: research

Dietary Inflammatory Score Is Associated With Incident Heart Failure In The Reasons For Geographic And Racial Differences In Stroke Study
Inflammation is a well-established risk factor for heart failure (HF) via processes that lead to atherosclerosis, myocardial fibrosis, and dysfunction. Dietary patterns can influence systemic inflammation, but an association between a “pro-inflammatory diet” and incident HF has not been reported.
Source: Journal of Cardiac Failure - April 1, 2023 Category: Cardiology Authors: Christine Park, Lauren Balkan, Joanna Bryan, James Shikany, Suzanne Judd, Roberd Bostick, Chanel Jonas, Madeline Sterling, Todd Brown, Scott Hummel, Pankaj Arora, Raegan Durant, Elizabeth Jackson, Emily Levitan, Monika Safford, Parag Goyal Tags: 206 Source Type: research

Mediterranean diet ‘can reduce heart attacks in people at higher risk’
First study of its kind finds diet can benefit hundreds of millions with obesity, diabetes or other risk factorsA Mediterranean diet can lower the risk of a heart attack, stroke or early death for hundreds of millions of people who have an increased possibility of cardiovascular disease, a global review of evidence suggests.A diet rich in olive oil, nuts, seafood, whole grains and vegetables has previously been linked to a number of benefits, and its effectiveness in helping healthy people to live longer is well known.Continue reading...
Source: Guardian Unlimited Science - March 29, 2023 Category: Science Authors: Andrew Gregory Health editor Tags: Food science Medical research Health & wellbeing Diets and dieting Heart attack Diabetes Life and style Society Source Type: news

Changes in Cardiovascular Health Across Midlife and Late-Life and Magnetic Resonance Imaging Markers of Cerebral Vascular Disease in Late-Life
CONCLUSIONS: Improving cardiovascular health within midlife and from midlife to late-life may prevent development of cerebral vascular disease.PMID:36951053 | DOI:10.1161/STROKEAHA.122.041374
Source: Atherosclerosis - March 23, 2023 Category: Cardiology Authors: Sanaz Sedaghat Yuekai Ji Jean-Philippe Empana Timothy M Hughes Thomas H Mosley Rebecca F Gottesman Michael Griswold Clifford R Jack Pamela L Lutsey Thomas T van Sloten Source Type: research

Interactive Effects of Dietary Inflammatory Index with BMI for the Risk of Stroke among Adults in the United States: Insight from NHANES 2011 –2018
ConclusionsThis cross-sectional study shows that the relationship between higher DII levels and the significant increase in stroke prevalence was further amplified in patients with SBP ≥140 mmHg and higher BMI.
Source: The Journal of Nutrition, Health and Aging - March 21, 2023 Category: Nutrition Source Type: research

The Association between Dietary Carotenoid Intake and Risk of Depression among Patients with Cardiometabolic Disease
This study aimed to assess the association of dietary carotenoid intake with risk of depression among patients with cardiometabolic disease.Data were obtained from the 2005 to 2014 National Health and Nutrition Examination Survey. Participants aged ≥ 20 years with any chronic cardiometabolic diseases, including diabetes, hypertension, coronary heart disease, heart failure, and stroke, were included in this cross-sectional study.We enrolled a total of 8655 cardiometabolic disease patients in the analysis. Compared to those in the lowest tertile, patients with cardiometabolic disease in the third tertiles of dietary α-car...
Source: International Heart Journal - March 17, 2023 Category: Cardiology Authors: Jie Liang Yuhao Wang Min Chen Source Type: research