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Total 16 results found since Jan 2013.

Increased Risk of Stroke Linked to Stress at Home, Work
Experiencing multiple stressful events or chronic stress at home or at work over the course of a year raises the risk of several types of stroke, astudy published today inJAMA Network Open has found. However, the study also suggests that having a greater sense of control over the situations and experiences that affect one ’s life—a greater locus of control—may help counter the impact of stress on stroke risk.Catriona Reddin, M.B., of the University of Galway in Ireland and colleagues analyzed data from 26,812 participants in the INTERSTROKE study, an international case-control study of risk factors for stroke. Among ...
Source: Psychiatr News - December 9, 2022 Category: Psychiatry Tags: home stress INTERSTROKE study JAMA Network Open locus of control work stress Source Type: research

The final puff: Can New Zealand quit smoking for good?
Smoking kills. Ayesha Verrall has seen it up close. As a young resident physician in New Zealand’s public hospitals in the 2000s, Verrall watched smokers come into the emergency ward every night, struggling to breathe with their damaged lungs. Later, as an infectious disease specialist, she saw how smoking exacerbated illness in individuals diagnosed with tuberculosis and HIV/AIDS. She would tell them: “The best thing you can do to promote your health, other than take the pills, is to quit smoking.” Verrall is still urging citizens to give up cigarettes—no longer just one by one, but by the thousands. As New...
Source: ScienceNOW - December 9, 2022 Category: Science Source Type: news

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Survey of Image Quality in Irish Stroke CT Protocols
Non-contrast computed tomography (NCCT) of the brain is a critical tool in the investigation of suspected acute ischaemic stroke. The recognition of subtle differences in attenuation values between normal brain parenchyma and regions of ischaemic tissue may be crucial to accurate and timely diagnosis. Radiologists at MMUH have been concerned with inconsistencies in image quality received from the various scanners and hospitals. Our study aimed to investigate the variation in imaging protocols for suspected acute stroke at different institutions in the regional hospital network using an objective measure of low contrast detectability (LCD).
Source: Physica Medica: European Journal of Medical Physics - April 1, 2021 Category: General Medicine Authors: David Caldwell, John Hynes, Peter MacMahon, Patrick Kenny Source Type: research

Audit of inpatient acute stroke services in a university teaching hospital, 2020
DiscussionUsing national and international  audit data as an institutional benchmark provides a standard with which a service can be compared to highlight areas for improvement. We identified mood screening, swallow screening, thrombectomy rates, length of stay and time to neuroimaging as key areas for development in our centre. We are cur rently completing a process map to determine cause, effect, and solutions, and we will implement change using PDSA methodology as per SQUIRE 2.0 guidelines. The results of the re-audit cycle for 2020 will be available in 2021 to inform our progress. Ongoing quality improvement is esse...
Source: Irish Journal of Medical Science - March 16, 2021 Category: General Medicine Source Type: research

Stroke consultant shortage 'hurtling towards crisis'
Some 48% of hospitals in England, Wales and Northern Ireland do not have the staff they need, figures suggest.
Source: BBC News | Health | UK Edition - January 17, 2020 Category: Consumer Health News Source Type: news

Country-Wide Analysis of Systemic Factors Associated With Acute Ischemic Stroke Door to Needle Time
Objective: Pre-hospital, in-hospital and patient factors are associated with variation in door to needle (DTN) time in acute ischemic stroke (AIS). Publications are usually from large single centers or multicenter registries with less reporting on national results. Materials and methods: All AIS patients treated with intravenous tissue plasminogen activator (iv-tPA) over 4 years (2013-2016) in Northern Ireland were recorded prospectively, including patient demographics, pre-hospital care, thrombolysis rate and DTN time. Logistic regression was performed to identify factors associated with DTN time. Results: 1201 patient...
Source: Frontiers in Neurology - June 25, 2019 Category: Neurology Source Type: research

Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain
This study was carried out in accordance with the recommendations of National Animal Welfare Authority, Ireland. The protocol was approved by the Animal Ethical Committee Trinity College Dublin and HPRA.Author ContributionsAS performed the experiments and wrote the paper; KH provided assistance in the design and analysis of the RNAseq experiment; DT contributed to sample extraction and establishment of the colony; and DT and MG designed and supervised all the parts of the research and the writing of the manuscript.FundingThe study was funded by the Wellcome Trust Grant WT079408/C/06/Z issued to MG, and by an SFI FN Funded ...
Source: Frontiers in Psychiatry - April 29, 2019 Category: Psychiatry Source Type: research

20 years of researching stroke through audit.
This article records and reviews some questions that have been answered using data from the audit: Is the rate of institutional care after rehabilitation a possible measure of outcome? Does stroke unit care in routine practice give the benefits shown in randomized controlled trials? How is the quality of stroke care affected by a patient's age and the time of their stroke? Do patient-reported measures match those obtained from the professionals recording of processes of care? How do the processes of care after stroke affect mortality? Is thrombolysis safe to use in patients over the age of 80? Do staffing levels matter? Do...
Source: Clinical Rehabilitation - June 1, 2018 Category: Rehabilitation Authors: Rudd AG, Hoffman A, Paley L, Bray B Tags: Clin Rehabil Source Type: research

Cerenovus Receives FDA Nod for EMBOTRAP II
Johnson & Johnson’s Cerenovus unit has received an FDA nod to market the EMBOTRAP II Revascularization Device. The device is a next generation stent retriever used to capture and remove life-threatening blood clots from the brain following an ischemic stroke. The EMBOTRAP II Device is designed to rapidly restore blood flow by gripping and retrieving clots within the neurovasculature, with minimal compression, protecting against further complications. The device is indicated for use within eight hours of stroke symptom onset. In the ARISE II study, which was submitted as part of the 510(k) application to FDA, neuroint...
Source: MDDI - May 21, 2018 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Source Type: news

Medtronic Finds Another Value-Based Care Partner
Dublin, Ireland-based Medtronic continues to lead the charge toward value-based care with a new five-year strategic partnership with Lehigh Valley Health Network (LVHN), an eight-hospital network in Northeastern Pennsylvania. The partnership is aimed at developing innovative, sustainable, and integrated value-based solutions to improve healthcare outcomes for LVHN's patients. The partnership will create programs that span more than 70 major medical conditions, with the goal of positively impacting as many as 500,000 patients and reducing their cost of care by $100 million.  The organizations said the partnership will leve...
Source: MDDI - February 28, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Medical Device Business Source Type: news

From a direct oral anticoagulant to warfarin: reasons why patients switch
This study was an analysis of prospectively collected data from a 4-year period surveying a warfarin dose adjustment clinic in a large city centre hospital with the primary objective to identify these reasons. In our clinic with 1791 patients annually under review, 40 patients were identified as having switched from a DOAC to warfarin with the most common reasons for switching being bleeding, re-thrombosis and renal deterioration. Other reasons included medication interactions, side effects, antiphospholipid syndrome, valvular replacement or arterial embolism. Clinical events following warfarin commencement were also recor...
Source: Irish Journal of Medical Science - December 21, 2017 Category: General Medicine Source Type: research

The Grass Is Green for Medtech on the Emerald Isle
You don’t have to be a medtech veteran to have heard of Ireland’s ties to the industry. Still, even those who have spent years working in medical devices and diagnostics may be surprised to learn that 14 of the top 15 global medtech companies—including Boston Scientific, DePuy Synthes, Medtronic, Teleflex, and many more—have facilities in Ireland. Why Ireland? Just what is drawing medtech to Ireland? The country has gained recognition as a frequent target for corporate inversion deals that enable companies to fall under more favorable corporate tax rates, but a 12.5% tax rate is just part of what brings medtech com...
Source: MDDI - November 14, 2017 Category: Medical Devices Authors: Marie Thibault Tags: Medical Device Business Source Type: news

Promoting evidence-based health care in Africa
Charles Shey Wiysonge, Director ofCochane  South Africa, gave an interview to the World Health Organization Bulletin. Here is a re-post , with premission, from their  recent publication.Charles Shey Wiysonge is devoted to encouraging better use of scientific evidence for health policies and programmes in African countries. He is the director of the South African Cochrane Centre, a unit of the South African Medical Research Council, and a professor of epidemiology and biostatistics at the department of Global Health in the Faculty of Medicine and Health Sciences at Stellenbosch University in South Africa. He was Chief Res...
Source: Cochrane News and Events - August 17, 2017 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Standardising care for heart attack (STEMI) patients, Ireland
Under a reform agenda, the Health Service Executive (HSE) in Ireland initiated the National Clinical Programme for Acute Coronary Syndrome (ACS) in 2010, as a joint venture with the Royal College of Physicians of Ireland (RCPI). Early attention was focussed on treatment of patients with ST elevation myocardial infarction (STEMI) as treatment varied nationally depending on distance from a Cardiac centre offering 24/7 primary Percutaneous Coronary Intervention (PPCI) (direct clot removal), a more effective treatment with less complications but requiring specialised facilities compared with thrombolysis (clot dissolving drug ...
Source: International Journal of Integrated Care - August 1, 2017 Category: Nursing Source Type: research