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Infectious Disease: Influenza

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3.49 Identification of and Response to Suicide in a Fellow Outpatient Clinic
Suicide is the second leading cause of death for individuals ages 10 to 24 years. More teenagers and young adults die from suicide than from cancer, heart disease, AIDS, birth defects, stroke, pneumonia, influenza, and chronic lung disease, combined. Each day in our nation, there is an average of more than 3470 suicide attempts by young adults attending high school. The main objectives of our literature review are to highlight the importance of recognizing postdischarge period in patients at risk of suicide, critically analyzing the risk and protective factors to formulate an individualized safety plan during transition, a...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2018 Category: Psychiatry Authors: Muhammad Zeshan, Paul G. Hammerness, Muhammad H. Majeed Source Type: research

The Dangers of Influenza and Benefits of Vaccination in Adults With Chronic Health Conditions
Influenza (flu) is a serious health concern in adults with certain chronic health conditions including diabetes, lung disease, and cardiovascular disease. Flu-related inflammation may exacerbate chronic lung diseases and has been shown to increase the risk of myocardial infarction and stroke long after resolution of the acute illness. Data from the 2017–2018 flu season show a disproportionate impact on adults with chronic health conditions. Despite strong evidence to support the benefits of annual flu vaccination in mitigating disease severity, reducing hospitalization rates, and disrupting viral transmission, vaccinatio...
Source: Infectious Diseases in Clinical Practice - November 1, 2018 Category: Infectious Diseases Tags: NFID Clinical Updates Source Type: research

Quality of Care Indicators in Patients with Sickle Cell Disease (SCD): Influenza Vaccination and Routine Eye Examination Are Associated with Outpatient Utilization but Not Acute Hospital Care, Whereas Comorbidity Indexes Are Strongly Associated with Both
In conclusion, outpatient-based candidate quality indicators of care examined (influenza vaccination and eye examination), were associated with increased outpatient utilization, but not acute visits or hospitalizations. Co-morbidity indexes have significant confounding effects on outpatient and hospital utilization. Administrative data based quality indicators of care such as influenza vaccination, as well as SCD specific comorbidity indexes warrant further studies as these may help better understand optimal allocation of health care resources for patients with SCD.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - November 21, 2018 Category: Hematology Authors: Adamkiewicz, T., Baltrus, P., Li, C., Carter-Wicker, K., Gaglioti, A. Tags: 903. Outcomes Research-Non-Malignant Hematology: Poster II Source Type: research

Home Based Primary Care for Patients with Sickle Cell Disease
Conclusion: Overall, home based primary care seems to be a promising alternative for pts with SCD. It had a significant impact on patient quality of care and may improve prescription adherence, but more data are needed to determine if it has an effect on healthcare utilization for pts with SCD.DisclosuresMoore: Ohio State University College of Medicine: Research Funding. Desai: FDA: Research Funding; Pfizer: Research Funding; University of Pittsburgh: Research Funding; Selexy/Novartis: Research Funding; NIH: Research Funding; Ironwood: Other: Adjudication Committee.
Source: Blood - November 21, 2018 Category: Hematology Authors: Moore, M. D., Schamess, A., Williams, N., Huang, Y., Menka, G., Desai, P. C. Tags: 901. Health Services Research-Non-Malignant Conditions: Poster III Source Type: research

Descriptive analysis of pharmacy services provided after community pharmacy screening
Conclusions Approximately one-third of participants received a pharmacy service within 3  months post-screening. Relatively large numbers of annual and follow-up medication reviews were delivered despite low eligibility for annual-only reviews and despite many missed opportunities for pharmacy service provision in at-risk patients. In-pharmacy screening may facilitate provision of some services, namely medication reviews, by providing opportunities to identify patients at-risk.
Source: International Journal of Clinical Pharmacy - November 26, 2018 Category: Drugs & Pharmacology Source Type: research

U.S. Life Expectancy Dropped for the Third Year in a Row. Drugs and Suicide Are Partly to Blame
U.S. life expectancy dropped in 2017 for the third consecutive year, as deaths by suicide and drug overdose continue to claim more American lives. The average American could expect to live to 78.6 years old in 2017, down from 78.7 in 2016, according to data released Thursday by the Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS). That decline may be modest, but it marks the third year in a row that life expectancy at birth has fallen — a noteworthy phenomenon, since the previous multiyear drop recorded by the NCHS was in the early 1960s. The modern trend seems to be pr...
Source: TIME: Health - November 29, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime public health Source Type: news

US Life Expectency Drops; Drug Overdoses & Suicide To Blame
By Susan Scutti, CNN (CNN) — Life expectancy in the United States declined from 2016 to 2017, yet the 10 leading causes of death remained the same, according to three government reports released Thursday. Increasing deaths due to drug overdoses and suicides explain this slight downtick in life expectancy, the US Centers for Disease Control says. Overdose deaths reached a new high in 2017, topping 70,000, while the suicide rate increased by 3.7%, the CDC’s National Center for Health Statistics reports. Dr. Robert Redfield, CDC director, called the trend tragic and troubling. “Life expectancy gives us a s...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 29, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Source Type: news

Influenza infection: An update for clinicians.
Authors: Blot M, Chavanet P, Piroth L Abstract Lower respiratory infections remain the deadliest communicable disease in the world. Influenza infections are particularly involved, whether intrinsically, or more frequently, by promoting bacterial infections and superinfections. The flu is also responsible for the decompensation of many comorbidities and could lead to some myocardial infarction and stroke. The effect of antiviral therapies is limited but preventives measures, such as vaccination, remain a major public health issue. The flu is a major challenge at all levels and all times, from vaccine prevention, to ...
Source: Revue de Medecine Interne - January 16, 2019 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Superbugs, Anti-Vaxxers Make WHO ’ s List Of 10 Global Health Threats
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 21, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Local TV Source Type: news

Prevalence of Comorbidities in Rheumatoid Arthritis and Evaluation of Their Monitoring in Clinical Practice: The Spanish Cohort of the COMORA Study
ConclusionsIn Spain, the prevalence of comorbidities and CV risk factors in RA patients with established and advanced disease is relatively high, and their management in clinical daily practice remains suboptimal.ResumenObjetivosDescribir la prevalencia de comorbilidades en pacientes con AR en España y discutir sobre su manejo en la clínica diaria utilizando los datos de la cohorte española del estudio internacional COMORA.MétodosSubanálisis nacional del estudio COMORA en el que se analizaron las características demográficas y clínicas de 200 pacientes con AR (1987 ACR) y las prácticas rutinarias para el cribado y...
Source: Reumatologia Clinica - February 28, 2019 Category: Rheumatology Source Type: research

Randomized controlled trial of influenza vaccine in patients with heart failure to reduce adverse vascular events (IVVE): Rationale and design
ConclusionThis is the largest randomized trial to test if influenza vaccine compared to control reduces adverse vascular events in high risk individuals.Trial registration number:Clinicaltrials.govNCT02762851
Source: American Heart Journal - March 12, 2019 Category: Cardiology Source Type: research

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research

Cerebrovascular Accident in a Pediatric Patient Presenting With Influenza
Acute ischemic stroke (AIS) in pediatric populations accounts for more than half of pediatric strokes and is associated with significant morbidity and mortality. Pediatric AIS can present with nonspecific symptoms or symptoms that mimic alternate pathology.
Source: The Journal of Emergency Medicine - April 22, 2019 Category: Emergency Medicine Authors: Parisa P. Javedani, Melissa Zukowski Tags: Clinical Communications: Pediatric Source Type: research

Cells to Society: "Gold Standard" Chicago Parent Program / Research News
This study was conducted to enhance the rate of advance care planning conversations and documentation by improving knowledge, attitudes, and skills of caregivers.      Read more   Violence and Trauma ...
Source: Johns Hopkins University and Health Systems Archive - October 18, 2019 Category: Nursing Source Type: news