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Total 239 results found since Jan 2013.

The spread of medical fake news in social media – The pilot quantitative study
ConclusionsAnalyzing social media top shared news could contribute to identification of leading fake medical information miseducating the society. It might also encourage authorities to take actions such as put warnings on biased domains or scientifically evaluate those generating fake health news.
Source: Health Policy and Technology - July 5, 2018 Category: Health Management Source Type: research

Effect of neuro-orthopaedic surgery for spastic equinovarus foot after stroke. A prospective longitudinal study based on a goal-centered approach.
CONCLUSIONS: This study confirms the efficacy of the neuro-orthopaedic surgical treatment of spastic equinovarus foot after stroke to improve walking capacities and to achieve personal goals in the body function and activity/participation domains of the ICF. PMID: 29904043 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - June 14, 2018 Category: Rehabilitation Authors: Deltombe T, Gilliaux M, Peret F, Leeuwerck M, Wautier D, Hanson P, Gustin T Tags: Eur J Phys Rehabil Med Source Type: research

Stroke incidence is highest in women and non-Hispanic blacks living with HIV in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort
Conclusion: Women and non-Hispanic Blacks living with HIV had the highest incidence rates of stroke/TIA. A concerted effort must be made to include PLWH from these at-risk groups in observational and interventional studies aimed at understanding stroke mechanisms and reducing stroke risk in HIV infection. Strategies to modify stroke risk in PLWH should employ a multipronged approach targeting vascular risk factors and engaging and retaining patients in HIV care.
Source: AIDS - May 11, 2018 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Transfusion-transmitted malaria masquerading as sickle cell crisis with multisystem organ failure.
CONCLUSIONS: Clinical suspicion for transfusion-related adverse events, including hemolytic transfusion reactions and transfusion-transmitted infections, should be high in typically and atypically immunocompromised patient populations (like SCD), especially those on chronic transfusion protocols. Manual blood smear review aids in the evaluation of patients with SCD presenting with severe vaso-occlusive crisis and MSOF and can alert clinicians to the need for initiating aggressive therapy like RBC exchange and artesunate therapy. PMID: 29524230 [PubMed - as supplied by publisher]
Source: Transfusion - March 9, 2018 Category: Hematology Authors: Maier CL, Gross PJ, Dean CL, Chonat S, Ip A, McLemore M, El Rassi F, Stowell SR, Josephson CD, Fasano RM Tags: Transfusion Source Type: research

Cause-specific mortality in the Kombewa health and demographic surveillance systems site, rural Western Kenya from 2011-2015.
CONCLUSIONS: The analysis established the main CODs among people of all ages within the area served by the Kombewa HDSS. We hope that information generated from this study will help better address preventable deaths in the surveyed community as well as help mitigate negative health impacts in other rural communities throughout the Western Kenya region. PMID: 29502491 [PubMed - in process]
Source: Global Health Action - March 7, 2018 Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research

Subtraction multiphase CT angiography: A new technique for faster detection of intracranial arterial occlusions
ConclusionSubMPCTA is a novel technique that aids in identifying small intracranial vessel occlusions in the suspected AIS patient. SubMPCTA increases confidence in interpretation and reduces the time taken to detect intracranial vessel occlusions.Key Points• SubMPCTA processes MPCTA data to better demonstrate intracranial arterial occlusions.• SubMPCTA increases confidence and speed of interpretation of MPCTA studies.• SubMPCTA may aid in rapidly differentiating acute ischaemic stroke from stroke mimics.
Source: European Radiology - March 2, 2018 Category: Radiology Source Type: research

General Medical, Mental Health, and Demographic Risk Factors Associated With Suicide by Firearm Compared With Other Means.
CONCLUSIONS: Medical providers should consider targeting suicide risk screening for patients with any mental disorder, TBI, epilepsy, HIV, psychogenic pain, stroke, and migraine. When suicide risk is detected, counseling on reducing access to lethal means should include both firearms and other means for at-risk groups. PMID: 29446332 [PubMed - as supplied by publisher]
Source: Psychiatric Services - February 17, 2018 Category: Psychiatry Tags: Psychiatr Serv Source Type: research

Lower-extremity Dynamometry as a Novel Outcome Measure in a Double-blind, Placebo-controlled, Feasibility Trial of Intravenous Immunoglobulin (IVIG) for HIV-associated Myelopathy
Conclusion: We conclude that an adequately powered clinical trial of IVIG for HIVM would likely require a prolonged recruitment period and multiple participating sites. Lower limb dynamometry is a useful outcome measure for HIVM, which might also be useful in other HIV-related gait disorders. KEYWORDS: Dynamometry, intravenous immunoglobulin (IVIG), human immunodeficiency virus (HIV), myelopathy INTRODUCTION Human immunodeficiency virus (HIV)-associated myelopathy (HIVM) is a rare but well-described neurologic complication of HIV; it was first described early in the acquired immunodeficiency syndrome (AIDS) epidemic, and i...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Current Issue Demyelinating Disease Movement Disorders Neurodegenerative Disease Neurology Original Research Primary Care Technology Trial Methodology Dynamometry human immunodeficiency virus (HIV) intravenous immu Source Type: research

10 Global Health Issues to Watch in 2018
January 19, 2018It ’s notallbad news.When we set out to compile our annual list of global health issues to watch this year, it seemed like all bad news. And true, that ’s often what we deal with in global health—the problems that need tackling, the suffering we can help alleviate.But then stories and columns likethis one cheer us up. They remind us that no matter how complicated and frustrating our work may get, fighting back against poverty and inequality works.There are and always will be global health challenges to face. But there ’s boundless hope, too. And a field full of determined health workers and other hu...
Source: IntraHealth International - January 19, 2018 Category: International Medicine & Public Health Authors: mnathe Source Type: news

Elevated ischemic stroke risk among women living with HIV infection
Conclusion: The increased risk of ischemic stroke among WLWH compared with HIV-uninfected women persisted after adjusting for both traditional and sex-specific stroke risk factors. Further investigation into the mechanisms of elevated stroke risk among WLWH, including immunologic factors, will be key for developing targeted preventive strategies for this at-risk population.
Source: AIDS - December 1, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Autophagy after subarachnoid hemorrhage: Can cell death be good?
Abstract Autophagy is a prosurvival, reparative process that maintains cellular homeostasis through lysosomal degradation of selected cytoplasmic components and programmed death of old, dysfunctional, or unnecessary cytoplasmic entities. According to growing evidence, autophagy shows beneficial effects following subarachnoid hemorrhage (SAH). SAH is considered one of the most devastating forms of stroke. Though autophagy is prosurvival and aids in repair, deregulated or excessive autophagy results in increased cell death, more brain injury, and worse outcome. The aim of this review lies in revealing the pathophysi...
Source: Current Neuropharmacology - November 23, 2017 Category: Drugs & Pharmacology Authors: Ho WM, Akyol O, Reis H, Reis C, McBride D, Thome C, Zhang J Tags: Curr Neuropharmacol Source Type: research

HIV-positive adults are under-treated for cardiovascular problems compared to those without HIV
This study provides evidence that U.S. policymakers and professional societies should focus on improving the quality of the cardiovascular care that people who are HIV-positive receive.AUTHORSStudy authors are Dr. Joseph Ladapo, Dr. Adam Richards, Cassandra DeWitt, Nina Harawa, Steven Shoptaw, Dr. William Cunningham and Dr. John Mafi, all of UCLA. Mafi is also associated with Rand Corporation.JOURNALThestudy is published in the Journal of the American Heart Association.FUNDINGGrants from the National Heart, Lung and Blood Institute, National Institute on Minority Health and Health Disparities, and National Institute of Men...
Source: UCLA Newsroom: Health Sciences - November 22, 2017 Category: Universities & Medical Training Source Type: news

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research

Use of direct oral anticoagulants for treatment of atrial fibrillation in patients with HIV: a review
Purpose of review Atrial fibrillation is increasingly common in the ageing population. Patients with atrial fibrillation and HIV have a higher stroke risk, with guidelines recommending anticoagulation in the majority. Whilst anticoagulation options have diversified in the last decade for the general population, there is limited evidence for the safety and efficacy of these medications when used concurrently with antiretroviral therapy. We review the potential for patients with HIV on antiretroviral therapy to have direct-acting oral anticoagulations (DOACs). Recent findings Several case reports have been published in ...
Source: Current Opinion in HIV and AIDS - November 1, 2017 Category: Infectious Diseases Tags: CARDIOVASCULAR DISEASE IN HIV INFECTED PERSONS: Edited by Franck Boccara and Cameron J. Holloway Source Type: research