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Total 239 results found since Jan 2013.

Automatic segmentation of ultrasound images of carotid atherosclerotic plaque based on Dense-UNet
CONCLUSION: The Dense-UNet network could realize the automatic segmentation of atherosclerotic plaque ultrasound images, and it could assist medical practitioners in plaque evaluation.PMID:35964217 | DOI:10.3233/THC-220152
Source: Technology and Health Care - August 14, 2022 Category: Medical Devices Authors: Chengliang Deng Jianhua Adu Shenghua Xie Zhaohuan Li Qingguo Meng Qingfeng Zhang Lixue Yin Bo Peng Source Type: research

Vessel wall magnetic resonance imaging of symptomatic middle cerebral artery atherosclerosis: A systematic review and meta-analysis
CONCLUSION: Based on current evidence, contrast enhancement and T1 hyperintensity on high-resolution MRI have high potential as imaging biomarkers of patients with MCA plaques at risk of ischemic events. Future prospective, longitudinal studies of intracranial-plaque high-resolution MRI are required to improve decision-making for the management of intracranial atherosclerotic plaques.PMID:35952437 | DOI:10.1016/j.clinimag.2022.08.001
Source: Atherosclerosis - August 11, 2022 Category: Cardiology Authors: Rongwei Yang Jiang Yuan Xiuen Chen Xufeng Xie Ziming Ye Chao Qin Source Type: research

ASPECT Score and Its Application to Vasospasm in Aneurysmal Subarachnoid Haemorrhage: a Case –Control Study
AbstractDelayed cerebral ischaemia (DCI) is a significant complication of aneurysmal subarachnoid haemorrhage (aSAH) and is strongly associated with poorer outcome. The Alberta Stroke Program Early Computer Tomography (ASPECT) score is an established scoring tool, used in acute ischaemic stroke, to quantify early ischaemic changes on CT head scans. We aim to identify if ASPECT scoring correlates with functional outcome in DCI following aSAH. Retrospective case –control study. Inclusion criteria: admission to the Department of Neurosurgery at Leeds Teaching Hospitals NHS Trust (a tertiary neurosurgical centre in the Unite...
Source: Translational Stroke Research - August 9, 2022 Category: Neurology Source Type: research

Effectiveness and implementation of SHared decision-making supported by OUTcome information among patients with breast cancer, stroke and advanced kidney disease: SHOUT study protocol of multiple interrupted time series
Introduction Within the value-based healthcare framework, outcome data can be used to inform patients about (treatment) options, and empower them to make shared decisions with their health care professional. To facilitate shared decision-making (SDM) supported by outcome data, a multicomponent intervention has been designed, including patient decision aids on the organisation of post-treatment surveillance (breast cancer); discharge location (stroke) and treatment modality (advanced kidney disease), and training on SDM for health care professionals. The SHared decision-making supported by OUTcome information (SHOUT) study ...
Source: BMJ Open - August 1, 2022 Category: General Medicine Authors: Hackert, M. Q. N., Ankersmid, J. W., Engels, N., Prick, J. C. M., Teerenstra, S., Siesling, S., Drossaert, C. H. C., Strobbe, L. J. A., van Riet, Y. E. A., van den Dorpel, R. M. A., Bos, W. J. W., van der Nat, P. B., van den Berg-Vos, R. M., van Schaik, S Tags: Open access, Health services research Source Type: research

The devastating effects of humeral nonunion on health-related quality of life
CONCLUSIONS: Humeral nonunions have a devastating effect on a patient's physical and mental health with HRQoL measures lower than patients with other chronic conditions, such as asthma, diabetes, AIDS, and stroke. We found that our patients, on average, would trade approximately 45% of their remaining lifespan for perfect health.PMID:35718254 | DOI:10.1016/j.jse.2022.05.012
Source: Hand Surgery - June 19, 2022 Category: Surgery Authors: Mark R Brinker Christopher M Loftis Justin D Khoriaty Warren R Dunn Source Type: research

Brain structure and stroke risk score in subjects without a history of atrial fibrillation
Scand Cardiovasc J. 2022 Dec;56(1):100-102. doi: 10.1080/14017431.2022.2074094.ABSTRACTCHA2DS2-VASc score system aids in clinical decision-making in subjects with atrial fibrillation (AF). Little is known on the association between CHA2DS2-VASc scores and brain structure in patients without cardiac arrhythmia. Detailed brain architecture analysis was performed. Assessment of bivariate correlation between the volume of segmented brain structures and Z-scores of CHA2DS2-VASc showed that higher risk scores correlated negatively and significantly with various brain framework. Our study confirms that a cluster of risk factors i...
Source: Scandinavian Cardiovascular Journal - May 13, 2022 Category: Cardiology Authors: Mateusz Wykretowicz Łukasz Gąsiorowski Anna K łusek-Zielińska Katarzyna Katulska Source Type: research

What Medications Prevent Delirium in Elderly Medical Inpatients?
This study demonstrated lower rates of delirium in the melatonin arm, with an impressive number needed to treat (NNT) below six patients; mortality and length of hospital stay were unaffected.3 A delirium-prevention effect of melatonin has not been reproduced in other studies, notably Jaiswal et al, which randomized patients to a placebo or 3 mg of melatonin and found no difference in rates of delirium prevention.7  The melatonin receptor agonist ramelteon also has small but favorable evidence for preventing non-ICU hospitalized delirium. This comes from a study of 67 patients aged 65 years or older who were randomized to...
Source: The Hospitalist - May 2, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Drug Therapy Geriatrics Key Clinical Questions Medication Source Type: research

Online Program Aids Behavior Changes in Stroke Survivors
WEDNESDAY, April 20, 2022 -- The online " Prevent 2nd Stroke " (P2S) behavior change intervention improves stroke survivors ' self-reported global ratings of health-related quality of life (HRQoL) at six months, according to a study published online...
Source: Drugs.com - Pharma News - April 20, 2022 Category: Pharmaceuticals Source Type: news

Strategies for treatment of disease-associated dementia beyond Alzheimer disease: An update
Curr Neuropharmacol. 2022 Apr 11. doi: 10.2174/1570159X20666220411083922. Online ahead of print.ABSTRACTMemory, cognition, dementia, and neurodegeneration are complexly interlinked processes through various mechanistic pathways leading to a range of clinical outcomes. These are strongly associated with pathological conditions like Alzheimer's disease, Parkinson's disease, schizophrenia, stroke and are a growing concern for their timely diagnosis and management. Several cognition-enhancing interventions for management include non-pharmacological interventions like diet, exercise, and physical activity, while pharmacological...
Source: Current Neuropharmacology - April 12, 2022 Category: Drugs & Pharmacology Authors: Khan Sabiya Samim Gopal L Khatik Ashok K Datusalia Source Type: research