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Infectious Disease: Herpes
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Total 194 results found since Jan 2013.

Risk of Stroke in Patients with Herpes Zoster: A Systematic Review and Meta-Analysis
Several observational studies suggest that herpes zoster (HZ) may increase the risk of stroke, but the results are inconsistent. Our study was designed to assess the association between HZ and the risk of stroke through a meta-analysis of cohort studies.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2016 Category: Neurology Authors: Sheng-Ye Yang, Hong-Xing Li, Xin-Hao Yi, Guang-Liang Han, Qiang Zong, Ming-Xing Wang, Xiao-Xiao Peng Source Type: research

What Genetics are Associated with Multiple Sclerosis?
Discussion Multiple sclerosis (MS) is “a chronic degenerative, often episodic disease of the central nervous system marked by patchy destruction of the myelin that surrounds and insulates nerve fibers, usually appearing in young adulthood and manifested by one or more mild to severe neural and muscular impairments, as spastic weakness in one or more limbs, local sensory losses, bladder dysfunction, or visual disturbances.” It is a chronic disease and therefore symptoms must occur more than once. The first episode is called an acute demyelinating attack. Fifteen to forty-five percent of children with their first...
Source: PediatricEducation.org - April 4, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Herpesvirus Infections and Childhood Arterial Ischemic Stroke: Results of the VIPS Study.
CONCLUSIONS: -Herpesviruses may act as a trigger for childhood AIS, even if the infection is subclinical. Antivirals like acyclovir might have a role in the prevention of recurrent stroke if further studies confirm a causal relationship. PMID: 26813104 [PubMed - as supplied by publisher]
Source: Circulation - January 26, 2016 Category: Cardiology Authors: Elkind MS, Hills NK, Glaser CA, Lo WD, Amlie-Lefond C, Dlamini N, Kneen R, Hod EA, Wintermark M, deVeber GA, Fullerton HJ, VIPS Investigators Tags: Circulation Source Type: research

Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States
Conclusions Stroke and MI rates are transiently increased after exposure to herpes zoster. We found no evidence for a role of zoster vaccination in these associations. These findings enhance our understanding of the temporality and magnitude of the association between zoster and acute cardiovascular events.
Source: PLoS Medicine - December 15, 2015 Category: Internal Medicine Authors: Caroline Minassian et al. Source Type: research

Do statins interfere with the flu vaccine?
Statins are powerful, unusual, and, like El Niño and Tom Cruise, not well understood. Statins have a huge upside. They improve survival after heart attacks and lower the risk of recurrent strokes. They are also the only cholesterol-lowering medications that have been clearly shown to reduce heart attacks and deaths in high-risk patients without heart disease. In addition to reducing cholesterol, statins also lower levels of inflammation in the body. Reducing inflammation probably helps statins to prevent heart attack and stroke. However, evidence is emerging that these statin effects may also have a downside, hindering th...
Source: New Harvard Health Information - November 30, 2015 Category: Consumer Health News Authors: John Ross, MD, FIDSA Tags: Cold and Flu Drugs and Supplements Health Heart Health Vaccines flu vaccine statins Source Type: news

Infectious Burden and Cognitive Decline in the Northern Manhattan Study
ConclusionA quantitative stroke risk‐weighted measure of IB explained variability in baseline executive function performance and associated with decline in memory. Past exposure to common infections may contribute to vascular cognitive impairment and warrants further study.
Source: Journal of the American Geriatrics Society - August 20, 2015 Category: Geriatrics Authors: Clinton B. Wright, Hannah Gardener, Chuanhui Dong, Mitsuhiro Yoshita, Charles DeCarli, Ralph L. Sacco, Yaakov Stern, Mitchell S. V. Elkind Tags: Clinical Investigations Source Type: research

Pilot study of antibodies against varicella zoster virus and human immunodeficiency virus in relation to the risk of developing stroke, nested within a rural cohort in Uganda
ConclusionsThis is the first prospective study to examine a biological measure of exposure to VZV prior to diagnosis of stroke and although we identified no significant association, in this small pilot, with limited characterisation of cases, we cannot exclude the possibility that the virus is causal for a subset. The impact of HIV on risk of stroke has not been well characterised and warrants further study.
Source: Tropical Medicine and International Health - July 23, 2015 Category: Tropical Medicine Authors: Gershim Asiki, Lisa Stockdale, Ivan Kasamba, Tobias Vudriko, Grace Tumwekwase, Tom Johnston, Pontiano Kaleebu, Anatoli Kamali, Janet Seeley, Robert Newton Tags: Original Article Source Type: research

Pilot study of antibodies against Varicella Zoster Virus (VZV) and human immunodeficiency virus (HIV) in relation to the risk of developing stroke, nested within a rural cohort in Uganda
ConclusionsThis is the first prospective study to examine a biological measure of exposure to VZV prior to diagnosis of stroke and although we identified no significant association, in this small pilot, with limited characterisation of cases, we cannot exclude the possibility that the virus is causal for a subset. The impact of HIV on risk of stroke has not been well characterised and warrants further study.This article is protected by copyright. All rights reserved.
Source: Tropical Medicine and International Health - June 17, 2015 Category: Tropical Medicine Authors: Gershim Asiki, Lisa Stockdale, Ivan Kasamba, Tobias Vudriko, Grace Tumwekwase, Tom Johnston, Pontiano Kaleebu, Anatoli Kamali, Janet Seeley, Robert Newton Tags: Original Article Source Type: research

Prospective surveillance of hospitalisations associated with varicella in New Zealand children
ConclusionVaricella has more associated morbidity than commonly perceived in immunocompetent children. Māori and PI children are more likely to have complications. This surveillance gives support for inclusion of universal varicella vaccine in the NZ NIS.
Source: Journal of Paediatrics and Child Health - June 3, 2015 Category: Pediatrics Authors: Sophie Chien‐Hui Wen, Emma Best, Tony Walls, Nigel Dickson, Hamish McCay, Elizabeth Wilson Tags: Original Article Source Type: research

The relationship between herpes zoster and stroke.
Abstract Varicella zoster virus (VZV) infects >95 % of the world population. Typically, varicella (chickenpox) results from primary infection. The virus then becomes latent in ganglionic neurons along the entire neuraxis. In immunocompromised individuals, VZV reactivates and causes herpes zoster (shingles), pain, and rash in 1-2 dermatomes. Multiple case reports showed a link between stroke and zoster, and recent studies have emerged which reveal that VZV infection of the cerebral arteries directly causes pathological vascular remodeling and stroke (VZV vasculopathy). In the past few years, several large epide...
Source: Herpes - February 26, 2015 Category: Infectious Diseases Authors: Nagel MA, Gilden D Tags: Curr Neurol Neurosci Rep Source Type: research

The Relationship Between Herpes Zoster and Stroke
Abstract Varicella zoster virus (VZV) infects >95 % of the world population. Typically, varicella (chickenpox) results from primary infection. The virus then becomes latent in ganglionic neurons along the entire neuraxis. In immunocompromised individuals, VZV reactivates and causes herpes zoster (shingles), pain, and rash in 1–2 dermatomes. Multiple case reports showed a link between stroke and zoster, and recent studies have emerged which reveal that VZV infection of the cerebral arteries directly causes pathological vascular remodeling and stroke (VZV vasculopathy). In the past few years, several large ep...
Source: Current Neurology and Neuroscience Reports - February 25, 2015 Category: Neuroscience Source Type: research

HCV, but not HIV, is a risk factor for cerebral small vessel disease
Conclusions: This tissue-based analysis of cerebral arteriolar disease demonstrates that HCV constitutes an independent risk, in addition to African American race, hypertension, and cART. Further study is needed to understand what aspects of HCV and cART contribute to cerebrovascular neuropathogenesis.
Source: Neurology Neuroimmunology and Neuroinflammation - September 4, 2014 Category: Neurology Authors: Morgello, S., Murray, J., Van Der Elst, S., Byrd, D. Tags: Other cerebrovascular disease/ Stroke, HIV Article Source Type: research

Growth of newborn babies' brains tracked
Conclusion This study has mapped out the growth rate of the major structures of the brain in 87 apparently healthy neonates from within a week of birth up to 90 days. A study of this nature can help our understanding of the growth and development of the brain and our ability to monitor brain development over time. The fact the investigation had no apparent side effects is also welcome. However, as the authors point out, the relatively small size of the study means the results cannot be used as a reference for normal development. Larger and more ethnically diverse studies would be required. The goal of establishing data ...
Source: NHS News Feed - August 12, 2014 Category: Consumer Health News Tags: Pregnancy/child Source Type: news