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Infectious Disease: SARS

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Total 1451 results found since Jan 2013.

The Great Contrast Shortage of 2022 —Lessons learnt in Australia
ConclusionOur findings demonstrate that the IBCM shortage crisis had a very significant impact on the delivery of healthcare. While V/Q scans could (partially) substitute for CTPA studies in suspected pulmonary emboli, there appeared to be no valid alternative for CTNA studies in stroke calls. The unexpected and critical shortage of IBCM forced healthcare professionals to conserve resources, prioritise indications, triage patients based on risk, explore alternate imaging strategies and prepare for similar events recurring in the future.
Source: Journal of Medical Imaging and Radiation Oncology - May 18, 2023 Category: Radiology Authors: Giles Kisby, James H Seow, Greg Schie, Constantine C Phatouros, Kay ‐Vin Lam, Tracey Muir, Sally Burrows, Paul M Parizel Tags: Medical Imaging —Original Article Source Type: research

Bioinformatics Approach to Identify the Influences of COVID-19 on Ischemic Stroke
In this study, bioinformatics approaches were utilized to explore potential pathogenic mechanisms and predict potential drugs that may be useful in the treatment of COVID-19 and IS. The GSE152418 and GSE122709 datasets were downloaded from the GEO website to obtain the common differentially expressed genes (DEGs) of the two datasets for further functional enrichment, pathway analysis, and drug candidate prediction. A total of 80 common DEGs were identified in COVID-19 and IS datasets for GO and KEGG analysis. Next, the protein-protein interaction (PPI) network was constructed and hub genes were identified. Further, transcr...
Source: Biochemical Genetics - May 15, 2023 Category: Genetics & Stem Cells Authors: Jiabao Zhu Xiangui Li Fanzhen Lv Weimin Zhou Source Type: research

Carotid free-floating thrombus in COVID-19: a cerebrovascular disorder of cytokine storm-related immunothrombosis
ConclusionsCOVID-19-induced immunothrombosis possibly played a significant pathogenic role in CFFT.
Source: Neurological Sciences - May 13, 2023 Category: Neurology Source Type: research

Viruses, Vol. 15, Pages 1140: The Risk Factors for Acute Cerebrovascular Accident (Stroke) in Patients with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)
This study investigates the risk factors, comorbidities, and outcomes in patients with SARS-VoV-2 infection and acute ischemic stroke compared to patients without these conditions. The present retrospective study was conducted in the King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia, during the period from April 2020 to February 2022. This study investigates the risk variables among the individuals who were diagnosed with either SARS-CoV-2 with stroke or patients with stroke alone. A total of 42,688 COVID-19 patients were registered, 187 cases of ...
Source: Viruses - May 10, 2023 Category: Virology Authors: Badi A. Alotaibi Jehad A. Aldali Hamzah J. Aldali Sultan Ayoub Meo Glowi A. Alasiri Emadeldin M. Elsokkary Naser D. Alotaibi Faizah Alotaibi Tags: Article Source Type: research

Letter to the Editor Regarding ‘A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?’
We read with interest the article by Ozdil et al. about a three day-old female neonate who was diagnosed with venous sinus thrombosis (VST) which was complicated by a subacute, partial ischemic stroke in the territory of the right middle cerebral artery.1 The age of the stroke was estimated at 14-28 days before birth.1 Because the mother suffered a mild coronvirus disease-19 (COVID-19) infection during the initial weeks of the third trimester (gestational weeks 27-30), VST in the fetus was causally related to the severe, acute respiratory syndrome-coronavirus type-2 (SARS-CoV-2) infection of the mother.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

The SARS-CoV-2 responsible for phlegmasia cerulea dolens: a case report
CONCLUSION: Although the severe acute respiratory syndrome coronavirus 2 remains a thrombogenic pathology, systematic anticoagulation is the subject of hypothesis. Hence the importance of regular monitoring of markers of vascular thrombosis.PMID:37008170 | PMC:PMC10060091 | DOI:10.1097/MS9.0000000000000152
Source: Annals of Medicine - April 3, 2023 Category: Internal Medicine Authors: Youssef Banana Husam Bashir Sara Boukabous Intissar Haddiya Yassamine Bentata Abdellah Rezziki Adnane Benzirar Omar El Mahi Source Type: research

Global research trends on COVID-19 and stroke: A bibliometric analysis
ConclusionOur bibliometric analysis provides a comprehensive overview of the current state of research on COVID-19 and stroke and highlights key areas of focus in the field. Optimizing the treatment of COVID-19-infected stroke patients and elucidating the underlying pathogenic mechanisms of COVID-19 and stroke co-morbidity are key areas of future research that will be beneficial in improving the prognosis of stroke patients during the ongoing COVID-19 epidemic.
Source: Frontiers in Neurology - April 3, 2023 Category: Neurology Source Type: research

Direct and indirect impact of SARS-CoV-2 on the brain
AbstractAlthough COVID-19 is mostly a pulmonary disease, it is now well accepted that it can cause a much broader spectrum of signs and symptoms and affect many other organs and tissue. From mild anosmia to severe ischemic stroke, the impact of SARS-CoV-2 on the central nervous system is still a great challenge to scientists and health care practitioners. Besides the acute and severe neurological problems described, as encephalopathies, leptomeningitis, and stroke, after 2  years of pandemic, the chronic impact observed during long-COVID or the post-acute sequelae of COVID-19 (PASC) greatly intrigues scientists worldwide....
Source: Human Genetics - April 1, 2023 Category: Genetics & Stem Cells Source Type: research

Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)
Elife. 2023 Mar 22;12:e86002. doi: 10.7554/eLife.86002.ABSTRACTCOVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional malaise, and cognitive dysfunction that last for months and impact everyday functioning, is referred to as Long COVID under the general category of post-acute sequelae of SARS-CoV-2 infection (PASC). PASC is highly heterogenous and may be associated with multisystem tissue damage/dysfunction including acute encephalitis, cardiopulmonary syndromes, fibrosis, hepatobiliary damages, gastrointestinal dysregulation, myocardial infarction, neuromuscular syndromes, neuropsychiatric di...
Source: Herpes - March 22, 2023 Category: Infectious Diseases Authors: Zaki A Sherif Christian R Gomez Thomas J Connors Timothy J Henrich William Brian Reeves RECOVER Mechanistic Pathway Task Force Source Type: research

Viral diseases of the nervous system-Selected new and old viruses
Nervenarzt. 2023 Mar 21:1-8. doi: 10.1007/s00115-023-01452-0. Online ahead of print.ABSTRACTViral diseases of the nervous system are ancient and poliomyelitis was described in Egypt as early as 2000 BC. They can cause a wide range of neurological symptoms, such as meningitis, encephalitis, meningoencephalitis, Guillain-Barré-like syndrome and stroke, often leaving mild to severe residuals. Depending on the pathogen, the symptoms appear quickly within hours, or lead to increasing chronic symptoms within 1 week or months. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was newly identified in January...
Source: Herpes - March 21, 2023 Category: Infectious Diseases Authors: Uta Meyding-Lamad é Eva Maria Craemer Source Type: research