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Total 1451 results found since Jan 2013.

Blood-brain barrier function in response to SARS-CoV-2 and its spike protein
Neurol Neurochir Pol. 2023 Feb 22. doi: 10.5603/PJNNS.a2023.0014. Online ahead of print.ABSTRACTThe typical manifestation of coronavirus 2 (CoV-2) infection is a severe acute respiratory syndrome (SARS) accompanied by pneumonia (COVID-19). However, SARS-CoV-2 can also affect t he b rain, c ausing c hronic n eurological s ymptoms, variously known as long, post, post-acute, or persistent COVID-19 condition, and affecting up to 40% of patients. The symptoms (fatigue, dizziness, headache, sleep disorders, malaise, disturbances of memory and mood) usually are mild and resolve spontaneously. However, some patients develop acute ...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Łukasz Suprewicz Krzysztof Fiedoruk Agata Czarnowska Marcin Sadowski Agnieszka Strzelecka Peter A Galie Paul A Janmey Alina Ku łakowska Robert Bucki Source Type: research

SARS-CoV-2 neurotropism and other possible causes of olfactory disorders in COVID-19
Neurol Neurochir Pol. 2023 Feb 20. doi: 10.5603/PJNNS.a2023.0013. Online ahead of print.ABSTRACTCoronavirus disease 2019 (COVID-19) is an acute infectious respiratory disease (AIRD) caused by infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first cases were diagnosed and reported in Wuhan, central China, in November 2019. The disease initially occurred locally. However, the number of infected individuals increased dynamically and spread worldwide. The most common symptoms of the SARS-CoV-2 infection include malaise, fever, dry cough and dyspnoea. Over time, reports of new COVID-19 sy...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Pawe ł Sowa Adam Dadok Monika Adamczyk-Sowa Source Type: research

Blood-brain barrier function in response to SARS-CoV-2 and its spike protein
Neurol Neurochir Pol. 2023;57(1):14-25. doi: 10.5603/PJNNS.a2023.0014. Epub 2023 Feb 22.ABSTRACTThe typical manifestation of coronavirus 2 (CoV-2) infection is a severe acute respiratory syndrome (SARS) accompanied by pneumonia (COVID-19). However, SARS-CoV-2 can also affect the brain, causing chronic neurological symptoms, variously known as long, post, post-acute, or persistent COVID-19 condition, and affecting up to 40% of patients. The symptoms (fatigue, dizziness, headache, sleep disorders, malaise, disturbances of memory and mood) usually are mild and resolve spontaneously. However, some patients develop acute and fa...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Łukasz Suprewicz Krzysztof Fiedoruk Agata Czarnowska Marcin Sadowski Agnieszka Strzelecka Peter A Galie Paul A Janmey Alina Ku łakowska Robert Bucki Source Type: research

SARS-CoV-2 neurotropism and other possible causes of olfactory disorders in COVID-19
Neurol Neurochir Pol. 2023;57(1):36-42. doi: 10.5603/PJNNS.a2023.0013. Epub 2023 Feb 20.ABSTRACTCoronavirus disease 2019 (COVID-19) is an acute infectious respiratory disease (AIRD) caused by infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first cases were diagnosed and reported in Wuhan, central China, in November 2019. The disease initially occurred locally. However, the number of infected individuals increased dynamically and spread worldwide. The most common symptoms of the SARS-CoV-2 infection include malaise, fever, dry cough and dyspnoea. Over time, reports of new COVID-19 sy...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Pawe ł Sowa Adam Dadok Monika Adamczyk-Sowa Source Type: research

How COVID-19 Changes the Heart —Even After the Virus Is Gone
While COVID-19’s effects on the lungs and respiratory system are well known, there is growing research suggesting that the virus is also affecting the heart, with potentially lasting effects. In a presentation at the annual meeting of the Biophysical Society, an international biophysics scientific group, Dr. Andrew Marks, chair of the department of physiology at Columbia University, and his colleagues reported on changes in the heart tissue of COVID-19 patients who had died from the disease, some of whom also had a history of heart conditions. The team conducted autopsy analyses and found a range of abnormalities, pa...
Source: TIME: Health - February 18, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

Before blaming SARS-CoV-2 for cerebrovascular disease in children, all differentials need to be ruled out
We read with interest the article by Spanelova et al. about four pediatric patients with cerebrovascular complications after a putative SARS-CoV-2 infection [1]. Patient-1 was diagnosed with subdural hematoma (SDH) and meningitis, patient-2 with cerebral vasculitis, patient-3 with lacunar stroke, and patient-4 with venous sinus thrombosis (VST) with haemorrhage [1]. It was concluded that SARS-CoV-2 infections in children can be complicated by cerebro-vascular disease [1]. The study is promising but raises concerns that should be discussed.
Source: Pediatric Neurology - February 14, 2023 Category: Neurology Authors: Josef Finsterer Tags: Correspondence Source Type: research

Cryoballoon Pulmonary Vein Isolation as First-Line Treatment for Typical Atrial Flutter
Conclusion Cryoballoon PVI as first-line treatment for AFL is equally effective compared with standard CTI ablation for preventing recurrence of atrial arrhythmia and better at preventing new-onset AF. Trial registration number NCT03401099.
Source: Heart - February 14, 2023 Category: Cardiology Authors: Gupta, D., Ding, W. Y., Calvert, P., Williams, E., Das, M., Tovmassian, L., Tayebjee, M. H., Haywood, G., Martin, C. A., Rajappan, K., Bates, M. G. D., Temple, I. P., Reichlin, T., Chen, Z., Balasubramaniam, R. N., Ronayne, C., Clarkson, N., Morgan, M., B Tags: Arrhythmias and sudden death Source Type: research

Inactivated whole-virion SARS-CoV-2 vaccines and long-term clinical outcomes in patients with coronary atherosclerosis disease in China: a prospective cohort study
CONCLUSIONS: Our results indicated no evidence of an increased ischemic or bleeding risk after vaccination with inactivated SARS-CoV-2 vaccine among Chinese patients with CAD, with limited statistical power.PMID:36756815 | DOI:10.1093/cvr/cvad031
Source: Atherosclerosis - February 9, 2023 Category: Cardiology Authors: Huajie Xu Jiaojiao Zheng Xin Zhao Qi Zhou Bing Fan Hongyi Wu Si Zhang Junbo Ge Source Type: research

Animal Models to Study Neurologic Manifestations of COVID-19
Comp Med. 2023 Jan 19. doi: 10.30802/AALAS-CM-22-000073. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the worldwide coronavirus (COVID-19) pandemic, has infected an estimated 525 million people with over 6 million deaths. Although COVID-19 is primarily a respiratory disease, an escalating number of neurologic symptoms have been reported in humans. Some neurologic symptoms, such as loss of smell or taste, are mild. However, other symptoms, such as meningoencephalitis or stroke, are potentially fatal. Along with surveys and postmortem evaluations on humans, scientis...
Source: Comparative Medicine - February 6, 2023 Category: Zoology Authors: Kelsey C Carpenter Jibing Yang Jiajie Jessica Xu Source Type: research