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Source: The American Journal of Cardiology
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Total 715 results found since Jan 2013.
Overtreatment and Undertreatment With Anticoagulation in Relation to Cardioversion of Atrial Fibrillation (the RHYTHM-AF Study)
In conclusion, ECV was frequently performed under appropriate antithrombotic therapy for most high-risk patients with atrial fibrillation, whereas PCV was frequently performed without appropriate antithrombotic therapy. To enhance pericardioversion stroke prevention, cardioversion algorithms should focus less on the type of conversion and more on stroke risk factors and atrial fibrillation duration.
Source: The American Journal of Cardiology - November 11, 2013 Category: Cardiology Authors: Gregory Y.H. Lip, Anselm K. Gitt, Jean-Yves Le Heuzey, Lori D. Bash, Christopher J. Morabito, Alexandra A. Bernhardt, Christine McCrary Sisk, François Chazelle, Harry J. Crijns, RHYTHM-AF Scientific Committee Tags: Arrhythmias and Conduction Disturbances Source Type: research
Comparison of the CHA2DS2-VASc, CHADS2, HAS-BLED, ORBIT, and ATRIA Risk Scores in Predicting Non –Vitamin K Antagonist Oral Anticoagulants-Associated Bleeding in Patients With Atrial Fibrillation
The increasing adoption of non –vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention in atrial fibrillation (AF) necessitates a reassessment of bleeding risk scores. Because known risk factors for bleeding are largely the same as for stroke, we hypothesize that stroke risk scores could also be used to identify patients with high bleeding risks. We aimed to compare the performance of 2 stroke risk scores (Congestive Heart failure, hypertension, Age ≥75 [doubled], Diabetes, Stroke [doubled], Vascular disease, Age 65–74, and Sex [female] [CHA2DS2-VASc] and Cardiac failure, Hypertension, Age, Diabetes, ...
Source: The American Journal of Cardiology - July 31, 2017 Category: Cardiology Authors: Xiaoxi Yao, Bernard J. Gersh, Lindsey R. Sangaralingham, David M. Kent, Nilay D. Shah, Neena S. Abraham, Peter A. Noseworthy Source Type: research
Self-Reported Snoring and Risk of Cardiovascular Disease Among Postmenopausal Women (from the Women's Health Initiative)
In conclusion, snoring is associated with a modest increased risk of incident CHD, stroke, and CVD after adjustment for CVD risk factors. Additional studies are needed to elucidate the mechanisms by which snoring might be associated with CVD risk factors and outcomes.
Source: The American Journal of Cardiology - December 7, 2012 Category: Cardiology Authors: Megan Sands, Eric B. Loucks, Bing Lu, Mary A. Carskadon, Katherine Sharkey, Marcia Stefanick, Judith Ockene, Neomi Shah, Kristen G. Hairston, Jennifer Robinson, Marian Limacher, Lauren Hale, Charles B. Eaton Tags: Preventive Cardiology Source Type: research
Non-Invasive Monitoring of Cerebral Perfusion During Transcatheter Aortic Valve Implantation Procedure
We read the report by Nuis et al on the frequency and cause of stroke during and after transcatheter aortic valve implantation (TAVI). The investigators reported a 9% stroke incidence (19 of 214 patients), with early (24 hours, mean 3.5 days after TAVI) stroke in 11 patients. They used brain computed tomographic findings to further analyze the cause of stroke. Interestingly, they found that 26% of strokes (5 patients) revealed lacunar lesions, which is widely regarded as caused by cerebral hypoperfusion in the presence of local atherosclerosis. Therefore, the investigators implied that all efforts should be made during TA...
Source: The American Journal of Cardiology - January 4, 2013 Category: Cardiology Authors: Cathy De Deyne, Ingrid Meex, Frank Jans, Kim Engelen, Herbert Gutermann, Jo Dens Tags: Readers' Comments Source Type: research
Effects of Valsartan Versus Amlodipine in Diabetic Hypertensive Patients With or Without Previous Cardiovascular Disease
In conclusion, the ARB- and the CCB-based treatments exerted similar protective effects of CVD events regardless of the presence of previous CVD. For stroke events, the ARB may have more protective effects than the CCB in diabetic hypertensive patients with previous CVD.
Source: The American Journal of Cardiology - September 16, 2013 Category: Cardiology Authors: Kentaro Yamashita, Takahisa Kondo, Takashi Muramatsu, Kunihiro Matsushita, Takanori Nagahiro, Kengo Maeda, Satoshi Shintani, Toyoaki Murohara Tags: Systemic Hypertension Source Type: research
Risk of Sudden Death and Outcome in Patients With Hypertrophic Cardiomyopathy With Benign Presentation and Without Risk Factors
In conclusion, in patients with HC without conventional risk factors and with no or mild symptoms, the risk of sudden death was not negligible, with an event rate of 0.6% per year. Heart failure and stroke-related death were less common and largely confined to older patients. These results underscore the need for a more accurate assessment of the sudden death risk in patients with HC.
Source: The American Journal of Cardiology - February 14, 2014 Category: Cardiology Authors: Paolo Spirito, Camillo Autore, Francesco Formisano, Gabriele Egidy Assenza, Elena Biagini, Tammy S. Haas, Sergio Bongioanni, Christopher Semsarian, Emmanuela Devoto, Beatrice Musumeci, Francesco Lai, Laura Yeates, Maria Rosa Conte, Claudio Rapezzi, Luca B Tags: Cardiomyopathy Source Type: research
Comparison of the CHA2DS2-VASc, CHADS2, HAS-BLED, ORBIT and ATRIA Risk Scores in Predicting Non-Vitamin K Antagonist Oral Anticoagulants-Associated Bleeding in Patients with Atrial Fibrillation
The increasing adoption of non-vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention in atrial fibrillation (AF) necessitates a reassessment of bleeding risk scores. Because known risk factors for bleeding are largely the same as for stroke, we hypothesize that stroke risk scores could also be used to identify patients with high bleeding risks. We aimed to compare the performance of two stroke risk scores (CHA2DS2-VASc and CHADS2) and three bleeding risk scores (HAS-BLED, ORBIT, and ATRIA) in predicting major and intracranial bleeding.
Source: The American Journal of Cardiology - July 31, 2017 Category: Cardiology Authors: Xiaoxi Yao, Bernard J Gersh, Lindsey R Sangaralingham, David M Kent, Nilay D Shah, Neena S Abraham, Peter A Noseworthy Source Type: research
Anticoagulant Agents for Atrial Fibrillation in Cancer Patients
In a recent article in the journal, Patell et al1 found CHADS2 (congestive heart failure, hypertension, age ≥ 75, diabetes mellitus, prior stroke/transient ischemic attack/thromboembolism) and CHA2DS2VASC (congestive heart failure, hypertension, age ≥ 75, diabetes mellitus, prior stroke/transient ischemic attack/thromboembolism, vascular disease, age 65-74, sex category [i.e., female]) to predict risk of ischemic stroke in cancer patients with baseline atrial fibrillation (AF). Although only 36% of patients received anticoagulant therapy, the risk of stroke generally appeared to be lower than in cancer-free individuals.
Source: The American Journal of Cardiology - February 3, 2018 Category: Cardiology Authors: Marc Sorigue, Edurne Sarrate, Mireia Franch-Sarto, Mireia Santos-Gomez, Elisa Orna Source Type: research
Meta-Analysis Comparing Percutaneous Closure Versus Medical Therapy for Patent Foramen Ovale
Patent foramen ovale (PFO) is the most common congenital heart defect with an estimated prevalence of 1 in 4 adults. The optimal treatment strategy for patients with PFO with cryptogenic stroke has long been debated. Early clinical trials, including Randomized Evaluation of Recurrent Stroke Comparing PFO Closure to Established Current Standard of Care Treatment (RESPECT) (NCT00465270), Patent Foramen Ovale and Cryptogenic Embolism (PC) (NCT00166257), and Evaluation of the STARFlex Septal Closure System in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen O...
Source: The American Journal of Cardiology - April 5, 2022 Category: Cardiology Authors: Chayakrit Krittanawong, Hafeez Ul Hassan Virk, Anirudh Kumar, Zhen Wang, Dhruv Mahtta, Umair Khalid, Ali E. Denktas, John J. Volpi, Hani Jneid Source Type: research
Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ≥75 Years of Age
In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
Source: The American Journal of Cardiology - December 16, 2013 Category: Cardiology Authors: Edward L. Hannan, Ye Zhong, Peter B. Berger, Gary Walford, Jeptha P. Curtis, Chuntao Wu, Ferdinand J. Venditti, Robert S.D. Higgins, Craig R. Smith, Stephen J. Lahey, Spencer B. King Tags: Coronary Artery Disease Source Type: research
Prognosis in Patients Hospitalized With Permanent and Nonpermanent Atrial Fibrillation in Heart Failure
In conclusion, in patients with AF and HF, the risk of admission for HF and risk of death were higher when AF was permanent, particularly in patients with preserved LVEF. Stroke risk did not differ according to the pattern of AF, whatever the LVEF.
Source: The American Journal of Cardiology - January 15, 2014 Category: Cardiology Authors: Sophie Taillandier, Anne Brunet Bernard, Benedicte Lallemand, Edouard Simeon, Lauriane Pericart, Nicolas Clementy, Dominique Babuty, Laurent Fauchier Tags: Heart Failure Source Type: research
Dabigatran in Catheter Ablation of Atrial Fibrillation: A Call for a Randomized Control Trial
We read the study by Sardar et al entitled Meta-Analysis of Risk of Stroke or Transient Ischemic Attack With Dabigatran for Atrial Fibrillation Ablation. Sardar et al have conducted a rigorous systematic review and meta-analysis on the risk of stroke and transient ischemic attack with the use of dabigatran in catheter ablation (CA) of atrial fibrillation (AF) in comparison to warfarin. They have reported higher risk of thromboembolic events (including stroke and transient ischemic attack) with the periprocedural use of dabigatran contrary to several other meta-analyses that have shown no statistically significant differ...
Source: The American Journal of Cardiology - March 28, 2014 Category: Cardiology Authors: Aref A. Bin Abdulhak, Abdur Rahman Khan, Alan P. Wimmer Tags: Readers' Comments Source Type: research
Future of Polypill Use for the Prevention of Cardiovascular Disease and Strokes
In conclusion, a polypill treatment strategy may be effective in the prevention of CVD and stroke, but, to be cost-effective, it may be reasonable to target patients with a high CACS and FRS.
Source: The American Journal of Cardiology - June 9, 2014 Category: Cardiology Authors: Steven G. Chrysant, George S. Chrysant Tags: Review Source Type: research
Quantitative Evaluation of Mitral Regurgitation Secondary to Mitral Valve Prolapse by Magnetic Resonance Imaging and Echocardiography
The present prospective study was designed to evaluate the accuracy of quantitative assessment of mitral regurgitant fraction (MRF) by echocardiography and cardiac magnetic resonance imaging (cMRI) in the modern era using as reference method the blinded multi-parametric integrative assessment of mitral regurgitation (MR) severity. 2D- and 3D- MRF by echocardiography (2D Echo MRF and 3D Echo MRF) were obtained by measuring the difference in left ventricular (LV) total stroke volume (obtained from either 2D or 3D acquisition) and aortic forward stroke volume normalized to LV total stroke volume.
Source: The American Journal of Cardiology - August 14, 2015 Category: Cardiology Authors: Caroline Le Goffic, Manuel Toledano, Pierre-Vladimir Ennezat, Camille Binda, Anne-Laure Castel, François Delelis, Pierre Graux, Christophe Tribouilloy, Sylvestre Maréchaux Source Type: research
Effects of Oral Anticoagulant Therapy in Medical Inpatients ≥65 Years With Atrial Fibrillation
In this retrospective cohort observational study, we investigated mortality, ischemic, and hemorrhagic events in patients ≥65 years with atrial fibrillation consecutively discharged from an Acute Geriatric Ward in the period 2010 to 2013. Stroke and bleeding risk were evaluated using CHA2DS2-VASC (congestive heart failure/left ventricular dysfunction, hypertension, aged ≥75 years, diabetes mellitus, stroke/transient ischemic attack/systemic embolism, vascular disease, aged 65 to 74 years, gender category) and HAS-BLED (hypertension, abnormal renal/liver function, stroke, bleeding history or predisposition, labile in...
Source: The American Journal of Cardiology - December 1, 2015 Category: Cardiology Authors: Mario Bo, Irene Sciarrillo, Federica Li Puma, Marco Badinella Martini, Yolanda Falcone, Marina Iacovino, Enrica Grisoglio, Elena Menditto, Gianfranco Fonte, Enrico Brunetti, Guido Maggiani, Giovanni Carlo Isaia, Fiorenzo Gaita Tags: Arrhythmias and Conduction Disturbances Source Type: research
