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Source: The American Journal of Cardiology
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Total 715 results found since Jan 2013.
Underuse of oral anticoagulants in patients with ischemic stroke and atrial fibrillation in China
Anticoagulant therapy is an effective stroke prevention measure for people with atrial fibrillation (AF) who are at high risk of ischemic stroke. However, it is reported that oral anticoagulants (OACs) are generally underused in clinical practice. A better awareness of current usage of anticoagulant therapy would enable prevention of stroke secondary to AF. Therefore, we determined the nationwide prevalence of AF and the frequency of OACs use among patients with ischemic stroke in China. Based on the China National Stroke Screening Survey (CNSSS), a representative nationwide sample of 1,252,703 adults over 40 years old dur...
Source: The American Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Jian Guo, Tianjia Guan, Siyuan Fan, Baohua Chao, Longde Wang, Yuanli Liu Source Type: research
Meta-Analysis of Randomized Clinical Trials Comparing the Impact of Implantable Loop Recorder Versus Usual Care After Ischemic Stroke for Detection of Atrial Fibrillation and Stroke Risk
Implantable loop recorder (ILR) is recommended to detect subclinical atrial fibrillation (AF) after cryptogenic stroke; however, the clinical outcomes of this practice is unclear. We conducted a systematic review and meta-analysis of randomized controlled trials to evaluate 12-month AF detection, change in oral anticoagulation (OAC), and recurrent stroke in ILR versus usual care after ischemic stroke. We searched Medline, Embase, Web of Science, Cochrane Library for randomized controlled trials comparing ILR with usual care after any ischemic stroke.
Source: The American Journal of Cardiology - October 28, 2021 Category: Cardiology Authors: Darae Ko, Qiying Dai, David B. Flynn, Nicholas A. Bosch, Robert H. Helm, Kevin M Monahan, Charlotte Andersson, Christopher D. Anderson, Allan J. Walkey Source Type: research
Prevalence of and Risk Factors for Silent Ischemic Stroke in Patients With Atrial Fibrillation as Determined by Brain Magnetic Resonance Imaging
Varied silent ischemic stroke (SS) prevalence occurs in patients with atrial fibrillation (AF). Stroke history is worth 2 points in the CHADS2 scoring system. An unknown proportion of patients with AF with a CHADS2 score of 0 or 1 have been undertreated for stroke prevention. We investigated SS risk factors using magnetic resonance imaging and estimated SS impact on clinical outcomes in patients with AF. We analyzed a total of 1,200 patients (400 with AF and 800 with sinus rhythm) who had brain magnetic resonance imaging performed for routine health checkups. Clinical outcomes including symptomatic stroke, dementia, and co...
Source: The American Journal of Cardiology - November 25, 2013 Category: Cardiology Authors: Myung-jin Cha, Hyo Eun Park, Min-ho Lee, Youngjin Cho, Eue-keun Choi, Seil Oh Tags: Arrhythmias and Conduction Disturbances Source Type: research
Ischemic Stroke Occurring During Intercourse in Young Women on Oral Contraceptives
We present 2 cases of young women taking oral contraceptives, each presenting with an ischemic stroke. Transthoracic echocardiography revealed a patent foramen ovale in one patient and an atrial septal defect in the other. The most likely cause of stroke in both patients is embolic. Despite conflicting evidence, young patients presenting with ischemic stroke and found to have a patent foramen ovale or atrial septal defect should be considered for possible device-based closure.
Source: The American Journal of Cardiology - May 19, 2014 Category: Cardiology Authors: P. Elliott Miller, Lorrel Brown, Paras Khandheria, Jon R. Resar Tags: Case Report Source Type: research
Impact of Co-morbidity on the Risk of First-Time Myocardial Infarction, Stroke, or Death After Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging
In conclusion, independently of co-morbidity level, an abnormal SPECT MPI scan was associated with an increased 10-year risk of myocardial infarction and all-cause death but not stroke.
Source: The American Journal of Cardiology - June 9, 2014 Category: Cardiology Authors: Astrid Blicher Schelde, Morten Schmidt, Morten Madsen, Karin Lottrup Petersen, Søren Steen Nielsen, Jørgen Frøkiær, Henrik Toft Sørensen, Christian Fynbo Christiansen Tags: Coronary Artery Disease Source Type: research
Effect of Obstructive Sleep Apnea on Frequency of Stroke in Patients with Atrial Fibrillation
Obstructive sleep apnea (OSA) is an independent risk factor for ischemic stroke that is not included in the usual cardioembolic risk assessments for patients with atrial fibrillation (AF). The aim of this study was to investigate the impact of OSA on stroke rate in patients with AF. Patients with AF and new diagnosis of OSA were identified from retrospective chart review. Those with a history of stroke at the time of the sleep study were excluded. The primary outcome was the incidence of stroke, determined by a physician investigator blinded to the results of polysomnography.
Source: The American Journal of Cardiology - November 29, 2014 Category: Cardiology Authors: Dmitry M. Yaranov, Athanasios Smyrlis, Natalia Usatii, Amber Butler, Joann R. Petrini, Jose Mendez, Mark K. Warshofsky Source Type: research
Meta-Analysis of Anticoagulation Use, Stroke, Thromboembolism, Bleeding, and Mortality in Patients With Atrial Fibrillation on Dialysis
Atrial fibrillation (AF) is common in patients on dialysis. Although randomized trials of anticoagulation for AF have demonstrated striking reductions in stroke, these trials did not recruit patients on dialysis. We thus undertook this systematic review and meta-analysis of observational studies including patients with AF on dialysis that reported associations of anticoagulation use. Twenty studies involving 529,741 subjects and 31,321 patients with AF on dialysis were identified. Anticoagulation was associated with a 45% (95% CI 13% to 88%) increased risk of any stroke, reflecting a nonsignificant 13% (95% CI −4% to 34...
Source: The American Journal of Cardiology - April 12, 2016 Category: Cardiology Authors: Christopher X. Wong, Ayodele Odutayo, Connor A. Emdin, Ned J. Kinnear, Michelle T. Sun Tags: Arrhythmias and Conduction Disturbances Source Type: research
High-Sensitivity C-Reactive Protein and Risk of Stroke in Atrial Fibrillation (from the Reasons for Geographic and Racial Differences in Stroke Study)
The relation between inflammation and prothrombotic state in atrial fibrillation (AF) is well recognized. This suggests a potential role for high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, in improving prediction of stroke in participants with AF. Cox proportional hazard analysis was used to examine the risk of stroke in 25,841 participants (40% black and 55% women) with and without AF who were enrolled in the Reasons for Geographic and Racial Differences in Stroke study from 2003 to 2007.
Source: The American Journal of Cardiology - September 13, 2016 Category: Cardiology Authors: Farah Z. Dawood, Suzanne Judd, Virginia J. Howard, Nita A. Limdi, James F. Meschia, Mary Cushman, George Howard, David M. Herrington, Elsayed Z. Soliman Tags: Arrhythmias and Conduction Disturbances Source Type: research
Sex Differences in the Trends of Hospitalizations for Acute Stroke among Patients with Atrial Fibrillation in the United States; 2005 - 2014
Female sex was included in stroke prediction algorithms in an attempt to improve anticoagulation rates in women with atrial fibrillation (AF). It is unclear if these efforts reduced stroke burden in women with AF. In order to bridge this literature gap, using the Nationwide Inpatient Sample (NIS), we assessed sex differences in the trends of hospitalizations for stroke among patients with AF in the United States; 2005 – 2014. International classification of diseases, 9th revision, clinical modification (ICD-9-CM) codes were used to abstract AF and stroke diagnoses.
Source: The American Journal of Cardiology - July 31, 2017 Category: Cardiology Authors: Ghanshyam Palamaner Subash Shantha, Amgad Mentias, Viraj Bhise, Anita Kumar, Tyler Rasmussen, Casey Adams, Kongkiat Chaikriangkrai, Ala Mohsen, Musab Alqasrawi, Gardar Sigurdsson, Abhishek Deshmukh, Prashant D. Bhave, Michael Giudici Source Type: research
Gender Differences in the Trends of Hospitalizations for Acute Stroke Among Patients With Atrial Fibrillation in the United States: 2005 to 2014
Female gender was included in stroke prediction algorithms in an attempt to improve anticoagulation rates in women with atrial fibrillation (AF). It is unclear if these efforts reduced stroke burden in women with AF. To bridge this literature gap, using the Nationwide Inpatient Sample, we assessed gender differences in the trends of hospitalizations for stroke among patients with AF in the United States in 2005 to 2014. International classification of diseases, 9th revision, clinical modification codes were used to abstract AF and stroke diagnoses.
Source: The American Journal of Cardiology - July 31, 2017 Category: Cardiology Authors: Ghanshyam Palamaner Subash Shantha, Amgad Mentias, Viraj Bhise, Anita Kumar, Tyler Rasmussen, Casey Adams, Kongkiat Chaikriangkrai, Ala Mohsen, Musab Alqasrawi, Gardar Sigurdsson, Abhishek Deshmukh, Prashant D. Bhave, Michael Giudici Source Type: research
Usefulness of CHADS2 and CHA2DS2-VASc Scores for Stroke Prediction in Patients With Cancer and Atrial Fibrillation
Stroke prediction scores have not been validated in patients with cancer and Atrial Fibrillation (AF). We aimed to identify unique risk factors and evaluate validity of CHADS2 and CHA2DS2-VASc scores to predict risk of stroke and mortality. A retrospective review of all cancer patients with pre-existing AF presenting from 2008 to 2014 was performed. Outcomes included ischemic stroke and mortality. Prognostic factors were identified with Fine& Gray regression for stroke and Cox proportional hazards analysis for survival.
Source: The American Journal of Cardiology - September 19, 2017 Category: Cardiology Authors: Rushad Patell, Alejandra Gutierrez, Lisa Rybicki, Alok A. Khorana Source Type: research
Usefulness of Rhythm Monitoring Following Acute Ischemic Stroke
Atrial fibrillation (AF) is a well-recognized risk factor for ischemic stroke, and AF-related strokes are typically severe.1,2 Recognizing AF as the underlying mechanism of stroke is important, as oral anticoagulation substantially reduces risk of recurrent stroke.3 –5 AF is frequently subclinical, however, and detected only after extended rhythm monitoring.6–8 As a result, current guidelines provide a Class IIa recommendation (moderate strength and good quality evidence) for extended rhythm monitoring (“∼ 30 days”) within six months following cryptog enic stroke (i.e., strokes with no apparent mechanism).
Source: The American Journal of Cardiology - February 19, 2021 Category: Cardiology Authors: Shaan Khurshid, Xinye Li, Jeffrey M. Ashburner, Ana T. Trisini Lipsanopoulos, Priscilla R. Lee, Aimee K. Lin, Darae Ko, Patrick T. Ellinor, Lee H. Schwamm, Emelia J. Benjamin, Steven J. Atlas, Daniel E. Singer, Christopher D. Anderson, Ludovic Trinquart, Source Type: research
Meta-Analysis of Racial Disparity in Utilization of Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation
Atrial fibrillation (AF) is the most common arrhythmia in the United States (US), and is associated with a substantial increase in the risk of ischemic stroke. Although prevalence of AF is lower in black individuals, they face a higher risk of stroke compared with patients of white race.1 Oral anticoagulant (OAC) therapy is the stroke prevention strategy in high-risk patients with AF. Despite the higher burden of ischemic stroke in Black AF patients, some studies suggest lower utilization of OAC among them.
Source: The American Journal of Cardiology - June 17, 2021 Category: Cardiology Authors: Izza Shahid, Muhammad Shariq Usman, Tariq Jamal Siddiqi, Faiza Zakaria, Mohamad Alkhouli Source Type: research
Relation of Electrocardiographic Abnormal P-Wave Axis With Stroke Mortality in the General Population
We examined the association of abnormal aPWA with stroke mortality in 7,359 participants (60.0 ± 13.4 years, 51.9% women, 49.8% White) without cardiovascular (CV) disease (CVD) from the Third National Health and Nutrition Examination Survey. aPWA was defined as any value75 °.
Source: The American Journal of Cardiology - August 6, 2022 Category: Cardiology Authors: Muhammad Imtiaz Ahmad, Luqman-Arafath TK, Muhammad Ali Anees, Lin Yee Chen, Elsayed Z. Soliman Source Type: research
Systematic Review and Meta-Analysis of Direct Oral Anticoagulants Versus Warfarin in Atrial Fibrillation With Low Stroke Risk
Oral anticoagulation (OAC) in patients with atrial fibrillation (AF) has been shown to prevent thromboembolic complications, but concerns about the increased risk of major bleeding warrant judicious consideration of the risks and benefits.1 Current guidelines recommend OAC prescription for patients with AF at high risk of stroke, as measured by CHA2DS2-VASc scores of ≥2 and ≥3 in men and women respectively.2–4 Men and women with scores of 1 and 2 respectively (i.e., a single nongender-related stroke risk factor) are deemed to be at low-moderate risk of stroke and OAC prescription may be considered to reduce thromboem...
Source: The American Journal of Cardiology - August 11, 2023 Category: Cardiology Authors: Khi Yung Fong, Yiong Huak Chan, Colin Yeo, Gregory Y.H. Lip, Vern Hsen Tan Source Type: research
