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Source: The American Journal of Cardiology

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Total 715 results found since Jan 2013.

Evaluation of Five Prognostic Scores for Prediction of Stroke, Thromboembolic and Coronary Events, All-Cause Mortality and Major Adverse Cardiac Events in Patients with Atrial Fibrillation and Coronary Stenting
Management of antithrombotic therapy in patients with atrial fibrillation (AF) and coronary stenting remains challenging and there is a need for efficient tools to predict their risk of different types of cardiovascular events and death. Several scores exist such as the CHA2DS2-VASc score, the GRACE score, the SYNTAX score, the Anatomical and Clinical Syntax II score (ACSS) and the REACH score. These five scores were investigated in AF patients with coronary stenting with the aim of determining which was most predictive for stroke/ thromboembolic (TE) events, non-lethal coronary events, all-cause mortality and Major Advers...
Source: The American Journal of Cardiology - June 13, 2016 Category: Cardiology Authors: Laurent Fauchier, Coralie Lecoq, Yann Ancedy, Karim Stamboul, Christophe Saint Etienne, Fabrice Ivanes, Denis Angoulvant, Dominique Babuty, Yves Cottin, Gregory Y.H. Lip Source Type: research

Economy Class Syndrome, patent foramen ovale and stroke
Whether or not air travel in a patient with patent foramen ovale (PFO) is a risk factor for cerebral embolism is unresolved. This is illustrated by a recent case report of the Massachusetts General Hospital in the New England Journal of Medicine of deep venous thrombosis and stroke associated with air travel. The discussant concluded that because of the relatively short flight “it seems unlikely that air travel was a major risk factor” 1. This may well be true for deep venous thrombosis per se, the risk of which has been shown to increase with duration of the flight 2.
Source: The American Journal of Cardiology - August 1, 2016 Category: Cardiology Authors: Franz H. Messerli, Stefano F. Rimoldi, Urs Scherrer Source Type: research

Influence of Left Ventricular Stroke Volume on Incident Heart Failure in a Population with Preserved Ejection Fraction (From the Strong Heart Study)
At a given level of left ventricular (LV) systolic function, LV pump performance (assessed by stroke index [SVi]) may differ, depending on LV size. We evaluated whether low SVi may be considered a marker of risk for incident congestive heart failure (HF), independent of LV geometry and systolic function, assessed by ejection fraction (EF) or midwall fractional shortening (MFS), in a large population-based sample with normal EF. Clinical and echocardiographic data from the second Strong Heart Study (SHS) exam, including 2,885 American Indians (59 ±8 years; 63% women) with normal EF (EF≥51% in men and EF≥55% in women) a...
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Marina De Marco, Eva Gerdts, Costantino Mancusi, Mary J. Roman, Mai Tone L ønnebakken, Elisa T. Lee, Barbara V. Howard, Richard B. Devereux, Giovanni de Simone Source Type: research

Usefulness of the MrWALLETS Scoring System to Predict First Diagnosed Atrial Fibrillation in Ischemic Stroke Patients
In this study we searched for echocardiographic parameters associated with first diagnosed AF, to form a scoring system for the identification of AF patients. We examined 571 ischemic stroke patients (72.7 ±13.5 years, 50.6% women), subdivided into 4 groups: documented cause without AF, first diagnosed AF, known paroxysmal AF, and permanent AF. All patients underwent transthoracic echocardiography, brain CT scan, carotid/vertebral ultrasound, and continuous ECG monitoring.
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Antonio Muscari, Andrea Bonfiglioli, Luca Faccioli, Marco Ghinelli, Donatella Magalotti, Francesco Manzetto, Anna Pontarin, Giovanni M. Puddu, Luca Spinardi, Eleonora Tubertini, Marco Zoli Source Type: research

Usefulness of the MrWALLETS Scoring System to Predict First Diagnosed Atrial Fibrillation in Patients With Ischemic Stroke
In this study, we searched for echocardiographic parameters associated with first diagnosed AF, to form a scoring system for the identification of patients with AF. We examined 571 patients with ischemic stroke (72.7  ± 13.5 years, 50.6% women), subdivided into 4 groups: documented cause without AF, first diagnosed AF, known paroxysmal AF, and permanent AF. All patients underwent transthoracic echocardiography, brain computed tomography scan, carotid/vertebral ultrasound, and continuous electrocardiographic monitoring.
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Antonio Muscari, Andrea Bonfiglioli, Luca Faccioli, Marco Ghinelli, Donatella Magalotti, Francesco Manzetto, Anna Pontarin, Giovanni M. Puddu, Luca Spinardi, Eleonora Tubertini, Marco Zoli Tags: Arrhythmias and Conduction Disturbances Source Type: research

Changing Trends of Atherosclerotic Risk Factors Among Patients with Acute Myocardial Infarction and Acute Ischemic Stroke
We aimed to evaluate the secular trends in demographics, risk factors as well as clinical characteristics of patients presenting with acute myocardial infarction (AMI) or acute ischemic stroke (AIS), using a large nationally representative dataset of in-hospital admissions. We used the 2003-2013 Nationwide Inpatient Sample. All admissions with primary diagnosis of AMI or AIS were included. Across 2003-2013, a total of 1,360,660 patients with AMI and 937,425 patients with AIS were included in the study.
Source: The American Journal of Cardiology - February 27, 2017 Category: Cardiology Authors: Shikhar Agarwal, Karan Sud, Badal Thakkar, Venu Menon, Wael A. Jaber, Samir R. Kapadia Source Type: research

Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality of Life Scores in Patients with Heart Failure (From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation ORBIT-AF)
This study aimed to determine the impact of heart failure (HF) on clinical outcomes in patients with atrial fibrillation (AF). We analyzed data from ORBIT-AF, a national registry of 10,135 AF patients to determine associations between HF as well as left ventricular ejection fraction (LVEF) and outcomes, including stroke, mortality, and hospitalization using Cox multivariable modeling.
Source: The American Journal of Cardiology - March 14, 2017 Category: Cardiology Authors: Tharian S. Cherian, Peter Shrader, Gregg C. Fonarow, Larry A. Allen, Jonathan P. Piccini, Eric D. Peterson, Laine Thomas, Peter R. Kowey, Bernard J. Gersh, Kenneth W. Mahaffey Source Type: research

Relation Between Estimated Cardiorespiratory Fitness and Atrial Fibrillation (From the REasons for Geographic and Racial Differences in Stroke Study)
This study included 10,126 participants (54.5% women, 35% African American, mean age 63.2 years) from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study who were free of AF at baseline. Baseline (2003-2007) e-CRF was determined using a previously validated non-exercise algorithm.
Source: The American Journal of Cardiology - March 14, 2017 Category: Cardiology Authors: Abhishek Bose, Wesley T. O ’Neal, Aleena Bennett, Suzanne E. Judd, Waqas T. Qureshi, Xuemei Sui, Virginia J. Howard, George Howard, Elsayed Z. Soliman Source Type: research

Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality-of-Life Scores in Patients With Heart Failure (from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation ORBIT-AF)
This study aimed to determine the impact of HF on clinical outcomes in patients with AF. We analyzed data from Outcomes Registry for Better Informed Treatment of Atrial Fibrillation, a national registry of 10,135 patients with AF to determine associations between HF and left ventricular ejection fraction (LVEF) and outcomes, including stroke, mortality, and hospitalization using Cox multivariable modeling.
Source: The American Journal of Cardiology - March 15, 2017 Category: Cardiology Authors: Tharian S. Cherian, Peter Shrader, Gregg C. Fonarow, Larry A. Allen, Jonathan P. Piccini, Eric D. Peterson, Laine Thomas, Peter R. Kowey, Bernard J. Gersh, Kenneth W. Mahaffey Tags: Arrhythmias and Conduction Disturbances Source Type: research

Rivaroxaban for Stroke Prevention in Patients with Non-Valvular Atrial Fibrillation and Active Cancer.
Rivaroxaban is broadly used for the primary prevention of stroke and systemic embolism in the general population with non-valvular atrial fibrillation (AF). However, there is little published evidence on the safety and efficacy of rivaroxaban for AF in patients with active cancer. The aim of this study was to assess the safety and efficacy of rivaroxaban in patients with active cancer and AF. Use of rivaroxaban in cancer patients at Memorial Sloan Kettering Cancer Center (MSKCC) is monitored in the setting of a Quality Assessment Initiative.
Source: The American Journal of Cardiology - April 26, 2017 Category: Cardiology Authors: Eva S. Laube, Anthony Yu, Dipti Gupta, Yimei Miao, Patrick Samedy, Jonathan Wills, Stephen Harnicar, Gerald A. Soff, Simon Mantha Source Type: research

Rivaroxaban for Stroke Prevention in Patients With Nonvalvular Atrial Fibrillation and Active Cancer
Rivaroxaban is broadly used for the primary prevention of stroke and systemic embolism in the general population with nonvalvular atrial fibrillation (AF). However, there is little published evidence on the safety and efficacy of rivaroxaban for AF in patients with active cancer. The aim of this study was to assess the safety and efficacy of rivaroxaban in patients with active cancer and AF. The use of rivaroxaban in patients with cancer at the Memorial Sloan Kettering Cancer Center is monitored in the setting of a Quality Assessment Initiative.
Source: The American Journal of Cardiology - April 26, 2017 Category: Cardiology Authors: Eva S. Laube, Anthony Yu, Dipti Gupta, Yimei Miao, Patrick Samedy, Jonathan Wills, Stephen Harnicar, Gerald A. Soff, Simon Mantha Tags: Arrhythmias and Conduction Disturbances Source Type: research

Comparison of Risk of Atrial Fibrillation among Employed Versus Unemployed (From the REasons for Geographic and Racial Differences in Stroke Study)
Involuntary unemployment due to job loss has been associated with increased risk of cardiovascular events. Whether it also is associated with increased risk of atrial fibrillation (AF) is currently unknown. Therefore, we examined this association in 8,812 participants residing mainly in the Southeastern United States (mean age 58.1 ± 7.8 years; 63.2%; women; 43.2% black) with data on employment status who were enrolled in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study between 2003 and 2007 after excluding those with voluntary unemployment (e.g.
Source: The American Journal of Cardiology - July 21, 2017 Category: Cardiology Authors: Elsayed Z. Soliman, Zhu-Ming Zhang, Suzanne Judd, Virginia J. Howard, George Howard Source Type: research

Outcome of Patients Receiving Thrombolytic Therapy While on Rivaroxaban for Nonvalvular Atrial Fibrillation (from Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation)
The safety of intravenous thrombolysis in patients taking rivaroxaban has not been well established. We retrospectively analyzed the outcomes of all patients who received thrombolytic therapy in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF). A review of medical and adverse event records for patients receiving thrombolytic therapy while enrolled in ROCKET AF was performed to determine their baseline characteristics, indications for thrombolysis, and type of agent used.
Source: The American Journal of Cardiology - August 7, 2017 Category: Cardiology Authors: Sean T. Chen, Anne S. Hellkamp, Richard C. Becker, Scott D. Berkowitz, G ünter Breithardt, Keith A.A. Fox, Werner Hacke, Jonathan L. Halperin, Graeme J. Hankey, Kenneth W. Mahaffey, Christopher C. Nessel, Jonathan P. Piccini, Daniel E. Singer, Manesh R. Source Type: research

Short- and Long-Term Mortality and Stroke Risk after Transcatheter Aortic Valve Implantation
No published studies have compared the outcome after transcatheter aortic valve implantation (TAVI) with the outcome in the general population. Thus, it is unknown whether TAVI restores normal life expectancy and stroke risk. Furthermore, despite the increasing use of TAVI, only little is known about the temporal trends for TAVI regarding patient characteristics and outcomes. We identified all Danish patients treated with TAVI from 2006-2014 (n=1,631) and 9,737 general population controls matched by sex, age and comorbidity.
Source: The American Journal of Cardiology - October 10, 2017 Category: Cardiology Authors: Lars Jakobsen, Christian J. Terkelsen, Lars S øndergaard, Ole D. Backer, Jens Aarøe, Henrik Nissen, Søren P. Johnsen, Evald H. Christiansen Source Type: research

Usefulness of the American Heart Association's Life Simple 7 to Predict the Risk of Atrial Fibrillation (From the REasons for Geographic and Racial Differences in Stroke REGARDS Study)
The American Heart Association has identified metrics of ideal cardiovascular (CV) health known as Life's Simple 7 (LS7). We determined the prospective relationship between the LS7 and incident AF in a biracial cohort. The Reasons for Geographic and Racial Differences in Stroke (REGARDS) study enrolled non-Hispanic black and white adults 45 years or older. This analysis included 9,576 REGARDS participants (mean age 63 ± 8.4 years; 57% women; 30% black) who were free of AF at baseline and completed a follow-up exam 9.4 years later.
Source: The American Journal of Cardiology - October 19, 2017 Category: Cardiology Authors: Parveen K. Garg, Wesley T. O'Neal, Adedotun Ogunsua, Evan L. Thacker, George Howard, Elsayed Z. Soliman, Mary Cushman Source Type: research