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Source: The American Journal of Cardiology
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Total 715 results found since Jan 2013.
Necropsy Findings Early After Transcatheter Aortic Valve Implantation for Aortic Stenosis
Although transcatheter aortic valve implantation has been available for 10 years, reports of cardiovascular morphologic studies after the procedure are virtually nonexistent. The investigators describe such findings in 2 patients, both 86 years of age, who died early (hours or several days) after transcatheter aortic valve implantation. Although the prosthesis in each was seated well, and each of the 3 calcified cusps of the native aortic valves was well compressed to the wall of the aorta, thus providing a good bioprosthetic orifice, the ostium of the dominant right coronary artery in each was obliterated by the native ri...
Source: The American Journal of Cardiology - November 26, 2012 Category: Cardiology Authors: William C. Roberts, Robert C. Stoler, Paul A. Grayburn, Robert F. Hebeler, Jong M. Ko, David L. Brown, William T. Brinkman, Michael J. Mack, Joseph M. Guileyardo Tags: Case Reports Source Type: research
Usefulness of Cardiac Biomarker Score for Risk Stratification in Stable Patients Undergoing Elective Cardiac Evaluation Across Glycemic Status
Several clinically available cardiac biomarkers have established their prognostic value in patients with acute coronary syndromes. However, their relative prognostic significance in stable subjects has not been prospectively validated, either individually or in combination. The aim of this study was to evaluate the extent to which B-type natriuretic peptide, myeloperoxidase, and high-sensitivity C-reactive protein alone or together could be prognostic biomarkers in 3,635 consecutive stable patients without acute coronary syndrome who underwent elective diagnostic coronary angiography. After adjusting for traditional risk f...
Source: The American Journal of Cardiology - December 7, 2012 Category: Cardiology Authors: W.H. Wilson Tang, Naveed Iqbal, Yuping Wu, Stanley L. Hazen Tags: Coronary Artery Disease Source Type: research
Comparison of Procedural Success and Long-Term Outcomes of Stent Thrombosis in Coronary Bypass Grafts Versus Native Coronary Arteries
Percutaneous coronary intervention within bypass grafts accounts for a significant percentage of total interventions. Bypass graft interventions are associated with an increased risk for stent thrombosis (ST), a condition that leads to significant morbidity and mortality. Despite this, the procedural characteristics and long-term outcomes of patients with bypass-graft ST have not been reported. The aim of the present study was to evaluate the procedural success and long-term outcomes of patients presenting with ST of coronary bypass grafts. Clinical and procedural characteristics of 205 ST cases at 5 academic hospitals wer...
Source: The American Journal of Cardiology - December 20, 2012 Category: Cardiology Authors: Stephen W. Waldo, Ehrin J. Armstrong, Khung Keong Yeo, Ehtisham Mahmud, Mitul Patel, Ryan Reeves, John S. MacGregor, Reginald I. Low, Jason H. Rogers, Kendrick A. Shunk Tags: Coronary Artery Disease Source Type: research
Frequency, Patient Characteristics, Treatment Strategies, and Resource Usage of Atrial Fibrillation (from the Italian Survey of Atrial Fibrillation Management ISAF Study)
In conclusion, in our study, the frequency of AF was 2 times greater than previously reported (approximately 0.90%), rate control was the most pursued treatment strategy, anticoagulants were still underused, and the success rate of AF ablation was lower than reported by referral centers.
Source: The American Journal of Cardiology - January 7, 2013 Category: Cardiology Authors: Massimo Zoni-Berisso, Alessandro Filippi, Maurizio Landolina, Ovidio Brignoli, Gaetano D'Ambrosio, Giampiero Maglia, Massimo Grimaldi, Giuliano Ermini Tags: Arrhythmias and Conduction Disturbances Source Type: research
Importance of Three-Dimensional Geometric Analysis in the Assessment of the Athlete's Heart
How the left ventricle remodels in response to a high-volume stimulus is important in evaluating the endurance athlete's heart. Marathoners and patients with isolated, moderate chronic compensated mitral regurgitation (MR) represent physiologic and pathologic forms of eccentric left ventricular (LV) remodeling in response to intermittent and chronic volume overload, respectively. Thus, in this study, magnetic resonance imaging with tissue tagging and 3-dimensional data analysis at rest were performed in 19 marathoners (mean age 39 ± 10 years, 47% women), 17 patients with isolated MR without coronary artery disease or medi...
Source: The American Journal of Cardiology - January 21, 2013 Category: Cardiology Authors: Chun G. Schiros, Mustafa I. Ahmed, Thriveni Sanagala, Wei Zha, David C. McGiffin, Marcas M. Bamman, Himanshu Gupta, Steven G. Lloyd, Thomas S. Denney, Louis J. Dell'Italia Tags: Miscellaneous Source Type: research
Alice in Wonderland of Drug-Eluting Stent for Unprotected Left Main Disease
We read the recent meta-analysis by Jang et al of 3 randomized trials and 9 observational studies (with 5,079 patients) comparing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) for unprotected left main coronary artery (ULMCA) disease. At 1-year follow-up, there were trends toward lower risk for death (odds ratio [OR] 0.68, 95% confidence interval [CI] 0.45 to 1.02, p = 0.06) and the composite end point of death, myocardial infarction, or stroke (OR 0.70, 95% CI 0.49 to 1.00, p = 0.05) in the DES group compared to the CABG group. However, target vess...
Source: The American Journal of Cardiology - March 15, 2013 Category: Cardiology Authors: Hisato Takagi, Takuya Umemoto Tags: Readers' Comments Source Type: research
Relation of Serum Adiponectin Levels to Number of Traditional Atherosclerotic Risk Factors and All-Cause Mortality and Major Adverse Cardiovascular Events (from the Copenhagen City Heart Study)
Adiponectin exerts anti-inflammatory and antiatherogenic effects and appears to protect against arteriosclerosis. Accordingly, an association between low concentrations of plasma adiponectin and cardiovascular (CV) disease has been demonstrated in several studies. In contrast, elevated plasma adiponectin has been associated with increased mortality and an increasing number of major adverse CV events (MACE). Because of these conflicting results, the true role of adiponectin remains to be elucidated. In the Copenhagen City Heart Study, we prospectively followed up 5,624 randomly selected men and women from the community with...
Source: The American Journal of Cardiology - February 4, 2013 Category: Cardiology Authors: Soren Lindberg, Rasmus Mogelvang, Sune H. Pedersen, Mette Bjerre, Jan Frystyk, Allan Flyvbjerg, Søren Galatius, Jan Skov Jensen Tags: Preventive Cardiology Source Type: research
Association of Serum Uric Acid and Cardiovascular Disease in Healthy Adults
In conclusion, the strong association of SUA levels with CVD in women, compared with the much lesser degree in men, highlights the necessity of stratifying by gender in investigations of cardiovascular risk factors and supports exploration of SUA as a marker of CVD risk in healthy populations.
Source: The American Journal of Cardiology - January 25, 2013 Category: Cardiology Authors: Shaye Kivity, Eran Kopel, Elad Maor, Fadi Abu-Bachar, Shlomo Segev, Yechezkel Sidi, David Olchovsky Tags: Preventive Cardiology Source Type: research
Renal Impairment in a “Real-Life” Cohort of Anticoagulated Patients With Atrial Fibrillation (Implications for Thromboembolism and Bleeding)
In conclusion, the presence of impaired renal function was closely related to thrombotic/vascular events, bleeding, and mortality in anticoagulated patients with AF. During follow-up, 1/5 of the patients had significant impairment in renal function. Importantly, normal or mild renal dysfunction at baseline did not exclude the subsequent development of severe renal dysfunction during the follow-up period.
Source: The American Journal of Cardiology - January 21, 2013 Category: Cardiology Authors: Vanessa Roldán, Francisco Marín, Hermógenes Fernández, Sergio Manzano-Fernández, Pilar Gallego, Mariano Valdés, Vicente Vicente, Gregory Y.H. Lip Tags: Arrhythmias and Conduction Disturbances Source Type: research
Safety of Continuous Anticoagulation With Dabigatran During Implantation of Cardiac Rhythm Devices
In conclusion, although no thromboembolic or major bleeding events were observed, additional studies are required to define the optimal antithrombotic management in the perioperative period.
Source: The American Journal of Cardiology - January 28, 2013 Category: Cardiology Authors: Christopher P. Rowley, Michael L. Bernard, William W. Brabham, Peter C. Netzler, Darren S. Sidney, Frank Cuoco, J. Lacy Sturdivant, Robert B. Leman, J. Marcus Wharton, Michael R. Gold Tags: Arrhythmias and Conduction Disturbances Source Type: research
Safety and Effect of Very Low Levels of Low-Density Lipoprotein Cholesterol on Cardiovascular Events
In conclusion, clinical trial evidence demonstrating the efficacy and safety of LDL cholesterol lowering to a very low level is essential to ascertain the benefits and risks in reducing the residual risk of vascular disease.
Source: The American Journal of Cardiology - February 1, 2013 Category: Cardiology Authors: John C. LaRosa, Terje R. Pedersen, Ransi Somaratne, Scott M. Wasserman Tags: Review Source Type: research
Two-Year Outcomes for Patients With Severe Symptomatic Aortic Stenosis Treated With Transcatheter Aortic Valve Implantation
In conclusion, the clinical outcome of TAVI is favorable. The use of both procedural devices and multiple techniques in the same institution is feasible and potentially desirable.
Source: The American Journal of Cardiology - February 18, 2013 Category: Cardiology Authors: Pablo Codner, Abid Assali, Danny Dvir, Hana Vaknin-Assa, Eyal Porat, Yaron Shapira, Marina Kupershmidt, Tamir Bental, Alexander Battler, Alexander Sagie, Ran Kornowski Tags: Valvular Heart Disease Source Type: research
Between a Rock and a Hard Place: Weighing Thrombotic Risk Against Bleeding Complications
The prospect of a further reduction of thrombotic end points (stent thrombosis, acute coronary syndromes, ischemic stroke) may seem appealing and encouraging to clinicians, interventional cardiologists in particular. Be that as it may, are we willing to accept a further reduction in thrombotic events at the trade-off of increasing hemorrhagic risk?
Source: The American Journal of Cardiology - April 25, 2013 Category: Cardiology Authors: Bartosz Hudzik, Lech Polonski Tags: Readers' Comments Source Type: research
Effect of Transcatheter (via Femoral Artery) Aortic Valve Implantation on the Platelet Count and Its Consequences
In conclusion, a decrease in platelet count is a common phenomenon after TAVI, and its severity is associated with poor outcomes.
Source: The American Journal of Cardiology - March 25, 2013 Category: Cardiology Authors: Romain Gallet, Aurelien Seemann, Masanori Yamamoto, Delphine Hayat, Gauthier Mouillet, Jean-Luc Monin, Pascal Gueret, Jean-Paul Couetil, Jean-Luc Dubois-Randé, Emmanuel Teiger, Pascal Lim Tags: Valvular Heart Disease Source Type: research
Effect of Cystatin C Levels on Angiographic Atherosclerosis Progression and Events Among Postmenopausal Women With Angiographically Decompensated Coronary Artery Disease (from the Women’s Angiographic Vitamin and Estrogen WAVE Study)
End-stage renal disease and mild renal insufficiency are associated with increased cardiovascular risk. Cystatin C, a novel marker of kidney function, was found to be associated with a higher frequency of cardiovascular events and mortality independent of glomerular filtration rate. It remained uncertain, however, whether enhanced cardiovascular risk associated with cystatin C is due to accelerated progression of atherosclerosis or to plaque instability. The aim of this study was to examine the effects of baseline cystatin C on annual change in coronary artery narrowing and clinical events in 423 postmenopausal women with ...
Source: The American Journal of Cardiology - March 18, 2013 Category: Cardiology Authors: Dhavalkumar Patel, Soha Ahmad, Angela Silverman, Joseph Lindsay Tags: Coronary Artery Disease Source Type: research
