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Source: The American Journal of Cardiology
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Total 715 results found since Jan 2013.
Prevalence of In-hospital Stroke Comparing MitraClip and Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) and mitraclip (MC) are increasingly utilized for the treatment of aortic stenosis (AS) and mitral regurgitation (MR), respectively. Perioperative stroke is one of the most serious complications following TAVI given the valve calcification and possible embolization during valve implantation, and thus ongoing trials are assessing the use of embolic protection device following TAVI. On the other hand, no such trials are being conducted on MC as the evidence of stroke following MC is lacking and MC does not share the same etiology with TAVI 1.
Source: The American Journal of Cardiology - January 5, 2021 Category: Cardiology Authors: Anas M. Saad, Keerat Rai Ahuja, Omar M. Abdelfattah, Mohamed M. Gad, Toshiaki Isogai, Manpreet Kaur, Grant W. Reed, James Yun, Amar Krishnaswamy, Samir R. Kapadia Source Type: research
Relation of Atrial Fibrillation to Cognitive Decline (from the REasons for Geographic and Racial Differences in Stroke REGARDS Study)
The association of atrial fibrillation (AF) with cognitive function remains unclear, especially among racially/geographically diverse populations. This analysis included 25,980 black and white adults, aged 48+, from the national REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort, free from cognitive impairment and stroke at baseline. Baseline AF was identified by self-reported medical history or electrocardiogram (ECG). Cognitive testing was conducted yearly with the Six Item Screener (SIS) to define impairment and at 2-year intervals to assess decline on: animal naming and letter fluency, Montreal Co...
Source: The American Journal of Cardiology - March 5, 2021 Category: Cardiology Authors: Margie J. Bailey, Elsayed Z. Soliman, Leslie A. McClure, George Howard, Virginia J. Howard, Suzanne E. Judd, Fred Unverzagt, Virginia Wadley, Bonnie C. Sachs, Timothy Hughes Source Type: research
Using Thoracic Artery Calcium Score to Predict Stroke
We are very enthused about the concept presented by Obisesan et al.1 regarding the use of thoracic artery calcium (TAC) as a predictor of stroke mortality. The logic on why aortic atherosclerosis is more closely related (to stroke mortality) than coronary artery calcification (CAC) scores is intriguing – we initially expected it to run in parallel but the explanation they give makes good sense. We also really appreciate the practicality – that it can be done easily with the data already acquired.
Source: The American Journal of Cardiology - June 17, 2021 Category: Cardiology Authors: Joseph C. Lee, Sushil Allen Luis, Alaa Alghamry Source Type: research
Trends in Cerebral Embolic Protection Device Use and Association With Stroke Following Transcatheter Aortic Valve Implantation
Stroke remains a serious complication of transcatheter aortic valve implantation (TAVI). Prior studies examining the association between cerebral embolic protection device (CEPD) use and stroke following TAVI have produced conflicting results. We used the Nationwide Readmissions Databases to identify all percutaneous (non-transapical) TAVIs performed in the US from July, 2017 to December, 2018. Overlap propensity score weighted logistic regression models were used to determine the association between CEPD use and outcomes.
Source: The American Journal of Cardiology - June 17, 2021 Category: Cardiology Authors: Dhaval Kolte, Sahil Khera, Salik Nazir, Neel M. Butala, Deepak L. Bhatt, Sammy Elmariah Source Type: research
The CHA2DS2-VASc Score for Risk Stratification of Stroke in Heart Failure With-vs-Without Atrial Fibrillation
A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association between the CHA2DS2-VASc score and outcomes. In HF patients with AF (n = 17,481) and without AF (n = 36,935), the 1 year incidence rate for ischemic stroke, thromboembolism, thromboembolism (without MI), and death were 2.7 and 2.0%; 10.3 and 7.9%; 4....
Source: The American Journal of Cardiology - July 14, 2021 Category: Cardiology Authors: George R. Marzouka, Harold Rivner, Vijay Mehta, Juan Lopez, Igor Vaz, Fei Tang, Hemant Ishwaran, Jeffrey J. Goldberger Source Type: research
Risk of Ischemic Stroke in Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Patients With Prior Stroke
It has not been well studied whether transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR) have lower risk of ischemic stroke (IS) in those with prior history of IS. From the Nationwide Readmission Database from October 2015 to November 2017, TAVI and SAVR above age 50 were identified with the International Classification of Diseases, Tenth Revision, Clinical Modification/Procedure Coding System codes. Transapical TAVI and SAVR with concomitant bypass, mitral, or tricuspid surgery were excluded.
Source: The American Journal of Cardiology - August 6, 2021 Category: Cardiology Authors: Tomo Ando, Said Ashraf, Alexandros Briasoulis, Hisato Takagi, Cindy L. Grines, Aaqib H. Malik Tags: Valvular Heart Disease Source Type: research
Effect of Duration of Anticoagulation in the Incidence of Stroke in Patients With Left-Ventricular Thrombus
The optimal duration of anticoagulation in patients with left-ventricular thrombus (LVT) is unclear. In the present study, we aimed to analyze the effect of treatment duration ( ≤12 months [short-term anticoagulation, (STA)] versus>12 months [long-term anticoagulation, (LTA)]) in the incidence of stroke and other secondary outcomes (acute myocardial infarction, bleeding, and mortality). Multivariate Cox regression was used to determine the association between treatment duration and stroke, adjusted for baseline embolic risk.
Source: The American Journal of Cardiology - October 12, 2022 Category: Cardiology Authors: Álvaro Lorente-Ros, Gonzalo L. Alonso-Salinas, Juan M. Monteagudo Ruiz, María Abellás-Sequeiros, José M. Vieítez-Florez, Diego Sánchez Vega, Jesús Álvarez-Garcia, Marcelo Sanmartín-Fernández, Marta Lorente-Ros, Susana del Prado Díaz, Covadonga Source Type: research
Advanced Echocardiography With Left Atrial Strain and Indexed Left Atrial Three-Dimensional Volume for Predicting Underlying Atrial Fibrillation After Cryptogenic Stroke
Cryptogenic stroke (CS) represents 1/3 of ischemic strokes. Atrial fibrillation (AF) can be detected in up to 30% of CS. Therefore, there is a clinical need for predicting AF to guide the optimal secondary prevention strategy. The evidence about the role of advanced echocardiography, including left atrial 3-dimensional (3D) index volume and left atrial strain (LAS) techniques, to predict underlying AF in this setting is lacking. From April 2019 to November 2021, 78 consecutive patients with ischemic stroke or transient ischemic attack with ABCD2 scale ≥4 of unknown etiology were prospectively recruited.
Source: The American Journal of Cardiology - October 25, 2022 Category: Cardiology Authors: Alberto Vera, Alberto Cecconi, Álvaro Ximénez-Carrillo, Carmen Ramos, Pablo Martínez-Vives, Beatriz Lopez-Melgar, Ancor Sanz-García, Guillermo Ortega, Clara Aguirre, José Vivancos, Luis Jesús Jiménez-Borreguero, Fernando Alfonso, DECRYTORING Study Source Type: research
Effect of Anticoagulation Duration on Stroke Incidence in Asian Patients With Left Ventricular Thrombus
Left ventricular thrombus (LVT) occurs in acute myocardial infarction (AMI) and in ischemic and nonischemic cardiomyopathies.1,2 LVT may result in embolic stroke.3 We read with interest the study by Lorente-Ros et al4 published in the American Journal of Cardiology. That study, conducted in a Spanish cohort, found that prolonged anticoagulation>12 months for LVT was associated with lower stroke risk. We aimed to study the generalizability of these results in an Asian population because the original article was a single-center study with limited representation.
Source: The American Journal of Cardiology - January 24, 2023 Category: Cardiology Authors: Fang Qin Goh, Aloysius S.T. Leow, Jamie S.Y. Ho, Benjamin Y.Q. Tan, Leonard L.L. Yeo, Ching-Hui Sia Source Type: research
Low Utility of Short-Term Rhythm Assessment Before Long-Term Rhythm Monitoring in Patients With Cryptogenic Stroke
Implantable cardiac monitors are routinely placed for long-term monitoring (LTM) after a period of negative short-term monitoring (STM) to increase atrial fibrillation (AF) detection after a cryptogenic stroke or transient ischemic attack (TIA). Optimizing AF monitoring after a cryptogenic stroke is critical to improve outcomes and reduce costs. We sought to compare the diagnostic yield of STM versus LTM, assess the impact of routine STM on hospitalization length of stay, and perform a financial analysis comparing the current model to a theoretical model wherein patients can proceed directly to LTM.
Source: The American Journal of Cardiology - July 11, 2023 Category: Cardiology Authors: Samuel J. Apple, David Flomenbaum, Matthew Parker, Sanya Chhikara, Aaron Stolarov, Jack Moser, Sheetal Vasundara Mathai, Jiyoung Seo, Neal Ferrick, Jay J. Chudow, Luigi Di Biase, Andrew Krumerman, Kevin J. Ferrick Source Type: research
Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction
We examined the hypothesis that atrial myopathy may be associated with ischemic stroke in patients with heart failure with preserved ejection fraction. This is an exploratory, post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial. Patients with sinus rhythm documented at baseline electrocardiogram and without known AF were included in this analysis.
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Kassem Farhat, Khaled Elkholey, Zain Ul Abideen Asad, Stavros Stavrakis Source Type: research
Temporal Trends in Risk Factors of Periprocedural Stroke in Patients Undergoing Percutaneous Coronary Intervention: Insights from the ACC NCDR CathPCI Registry
Periprocedural stroke complicates up to 1% of patients undergoing percutaneous coronary intervention (PCI) and is associated with increased morbidity, mortality, and subsequent health care resource utilization.1 –5 Contemporary reports suggest that despite iterative procedural evolution in PCI (e.g., smaller catheters, radial access, and potent pharmacotherapy), periprocedural stroke rates have not improved over the last few years, with our recent analysis suggesting these rates may be in fact be rising, likely as a result of an increasingly co-morbid population3 and higher procedural complexity.
Source: The American Journal of Cardiology - August 8, 2023 Category: Cardiology Authors: Adam J. Nelson, Rebecca Young, Imran H. Tarrar, Daniel Wojdyla, Tracy Y. Wang, Rajendra H. Mehta Tags: Brief Report Source Type: research
Troponin T in Acute Ischemic Stroke
In conclusion, elevated cTnT can be frequently detected in patients with AIS. To reliably identify patients with current acute myocardial impairment, more in-depth clinical investigation is needed.
Source: The American Journal of Cardiology - April 8, 2013 Category: Cardiology Authors: Michal Král, Daniel Šaňák, Tomáš Veverka, Martin Hutyra, David Vindiš, Anna Kunčarová, Andrea Bártková, Tomáš Dorňák, Marija Švábová, Veronika Kubíčková, Jana Zapletalová, Roman Herzig, David Školoudík Tags: Miscellaneous Source Type: research
Effect of Sustaining Lifestyle Modifications (Nonsmoking, Weight Reduction, Physical Activity, and Mediterranean Diet) After Healing of Myocardial Infarction, Percutaneous Intervention, or Coronary Bypass (from the REasons for Geographic and Racial Differences in Stroke Study)
Guidelines recommend lifestyle modification for patients with coronary heart disease (CHD). Few data demonstrate which lifestyle modifications, if sustained, reduce recurrent CHD and mortality risk in cardiac patients after the postacute rehabilitation phase. We determined the association between ideal lifestyle factors and recurrent CHD and all-cause mortality in REasons for Geographic and Racial Differences in Stroke study participants with CHD (n = 4,174). Ideal lifestyle factors (physical activity ≥4 times/week, nonsmoking, highest quartile of Mediterranean diet score, and waist circumference
Source: The American Journal of Cardiology - April 3, 2014 Category: Cardiology Authors: John N. Booth, Emily B. Levitan, Todd M. Brown, Michael E. Farkouh, Monika M. Safford, Paul Muntner Tags: Coronary Artery Disease Source Type: research
Relation Between Stroke Volume Index to Risk of Death in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Left Ventricular Function
The aim of the present study was to evaluate whether assessment of stroke volume index (SVI) can be used to improve risk stratification among patients with low-gradient severe aortic stenosis and preserved ejection fraction (EF). Study population comprised 409 patients with aortic valve area ≤1.00 cm2, mean gradient
Source: The American Journal of Cardiology - May 19, 2014 Category: Cardiology Authors: Elad Maor, Roy Beigel, Avishay Grupper, Rafael Kuperstein, Ilan Hai, Diego Medvedofsky, Olga Perelstein, Israel Mazin, Asaf Ziv, Ilan Goldenberg, Micha S. Feinberg, Sagit Ben Zekry Tags: Valvular Heart Disease Source Type: research
