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Source: The American Journal of Cardiology
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Total 715 results found since Jan 2013.
Therapy for Triggered Acute Risk Prevention in Subjects at Increased Cardiovascular Risk
In conclusion, it is feasible for those with increased CVD risk to identify potential triggers of acute CVD and to take targeted therapy at the time of these triggers.
Source: The American Journal of Cardiology - April 5, 2013 Category: Cardiology Authors: Geoffrey H. Tofler, Monica Spinaze, Elizabeth Shaw, Thomas Buckley Tags: Preventive Cardiology Source Type: research
Development and Validation of a Cardiovascular Risk Assessment Model in Patients With Established Coronary Artery Disease
In conclusion, in patients with established coronary artery disease, the risk of cardiovascular mortality during longer term follow-up can be adequately predicted using the clinical characteristics available at baseline. However, the prediction of nonfatal outcomes, both separately and combined with fatal outcomes, poses major challenges for clinicians and model developers.
Source: The American Journal of Cardiology - April 3, 2013 Category: Cardiology Authors: Linda Battes, Rogier Barendse, Ewout W. Steyerberg, Maarten L. Simoons, Jaap W. Deckers, Daan Nieboer, Michel Bertrand, Roberto Ferrari, Willem J. Remme, Kim Fox, Johanna J.M. Takkenberg, Eric Boersma, Isabella Kardys Tags: Coronary Artery Disease Source Type: research
Frequency, Determinants and Prognostic Implications of Infectious Complications After Transcatheter Aortic Valve Implantation
This study included 298 consecutive patients from 2 centers who underwent TAVI from November 2005 to November 2011. IHI during the hospital stay was defined on the basis of symptoms and signs assessed by the attending physician in the cardiac care unit or medium care unit in combination with all technical examinations performed to confirm infection. IHI after TAVI was observed in 58 patients (19.5%): urinary tract infections in 25 patients (43.1%), pneumonia in 12 patients (20.7%), and access-site infections in 7 patients (12.1%). In 12 patients (20.7%), the site of infection could not be determined, and 2 patients (3.4%) ...
Source: The American Journal of Cardiology - April 8, 2013 Category: Cardiology Authors: Robert M.A. van der Boon, Rutger-Jan Nuis, Luis M. Benitez, Nicolas M. Van Mieghem, Sergio Perez, Lidsa Cruz, Robert-Jan van Geuns, Patrick W. Serruys, Ron T. van Domburg, Antonio E. Dager, Peter P.T. de Jaegere Tags: Valvular Heart Disease Source Type: research
Comparison of Characteristics and Short-Term Outcome From Fungal Infective Endocarditis in Prosthetic Valve Endocarditis Versus Native Valve Endocarditis
In conclusion, fungal IE is associated with high mortality and recurrence rates. Surgery performed in selected cases may improve the outcomes, but the recurrence rate remains high.
Source: The American Journal of Cardiology - April 5, 2013 Category: Cardiology Authors: Xiao-lu Sun, Jian Zhang, Guo-gan Wang, Xiao-feng Zhuang, Yan-min Yang, Jun Zhu, Hui-qiong Tan, Li-tian Yu Tags: Valvular Heart Disease Source Type: research
Left Ventricular Diastolic Function and Long-Term Outcomes in Patients With Normal Exercise Echocardiographic Findings
The objective of the present study was to determine whether diastolic dysfunction (DD) is associated with outcomes in the absence of myocardial ischemia. We studied 2,835 patients undergoing exercise echocardiography from January 2006 through December 2006 who had normal systolic function (ejection fraction ≥50%) and an absence of exercise-induced wall motion abnormalities. Diastolic function was graded as normal, mild DD, or moderate to severe DD. Medical records review and patient contact were undertaken to determine mortality, cardiovascular events (i.e., death, myocardial infarction, or stroke), incident heart failur...
Source: The American Journal of Cardiology - April 22, 2013 Category: Cardiology Authors: S. Michael Gharacholou, Christopher G. Scott, Paul Y. Takahashi, Vuyisile T. Nkomo, Robert B. McCully, Nowell M. Fine, Patricia A. Pellikka Tags: Coronary Artery Disease Source Type: research
Comparison of Benazepril Plus Amlodipine or Hydrochlorothiazide in High-Risk Patients With Hypertension and Coronary Artery Disease
In conclusion, our findings suggest that the combination of B+A should be preferentially used for older patients with high-risk, stage 2 hypertension.
Source: The American Journal of Cardiology - April 15, 2013 Category: Cardiology Authors: George Bakris, Alexandros Briasoulis, Bjorn Dahlof, Kenneth Jamerson, Michael A. Weber, Roxzana Y. Kelly, Allen Hester, Tsushung Hua, Dion Zappe, Bertram Pitt, ACCOMPLISH Investigators Tags: Systemic Hypertension Source Type: research
Comparison of the Efficacy and Safety of Two Rivaroxaban Doses in Acute Coronary Syndrome (from ATLAS ACS 2–TIMI 51)
In conclusion, the 2 doses of rivaroxaban reduced cardiovascular events in patients with recent acute coronary syndromes treated with antiplatelet therapies; however, the 2.5-mg dose was associated with lower mortality and fewer bleeding complications than the 5-mg dose. Thus, the addition of rivaroxaban 2.5 mg twice daily offers a more favorable balance of efficacy and safety in patients with recent acute coronary syndromes.
Source: The American Journal of Cardiology - May 28, 2013 Category: Cardiology Authors: Jessica L. Mega, Eugene Braunwald, Stephen D. Wiviott, Sabina A. Murphy, Alexei Plotnikov, Nina Gotcheva, Mikhail Ruda, C. Michael Gibson Tags: Coronary Artery Disease Source Type: research
Thrombocytopenia in Patients With Atrial Fibrillation on Oral Anticoagulation Undergoing Percutaneous Coronary Intervention
In conclusion, mild to moderate baseline thrombocytopenia does not seem to have a clinically significant effect on bleeding or thrombotic or thromboembolic complications after PCI in these frail patients receiving multiple antithrombotic drugs.
Source: The American Journal of Cardiology - May 13, 2013 Category: Cardiology Authors: Tuomas Kiviniemi, Pasi Karjalainen, Andrea Rubboli, Axel Schlitt, Petri Tuomainen, Matti Niemelä, Mika Laine, Fausto Biancari, Gregory Y.H. Lip, K.E. Juhani Airaksinen Tags: Coronary Artery Disease Source Type: research
Cardiovascular Care for Women: The 10-Q Report and Beyond
Abstract: According to The National Coalition for Women's Health Research's 10Q Report: Advancing women's heart health through improved research, diagnosis, and treatment published in June 2011, cardiovascular disease (CVD), a term used to describe diseases of the heart or blood vessels, is the leading cause of death for women in the United States, causing more than 420,000 deaths among women annually. Experts estimate that one in two women will die of heart disease or stroke compared with one in 25 women who will die of breast cancer. Despite the fact that more women than men die each year of heart disease and that there...
Source: The American Journal of Cardiology - August 1, 2013 Category: Cardiology Authors: Nanette K. Wenger, Sharonne N. Hayes, Carl J. Pepine, William C. Roberts Tags: Multimedia Activities Source Type: research
Applying Antithrombotic Therapies to Improve Outcomes in Patients With Atrial Fibrillation
Abstract: Approximately 15% to 25% or 75,000 ischemic strokes are attributed to atrial fibrillation annually within the United States. Atrial fibrillation is the most frequently diagnosed cardiac arrhythmia and affects more than 2.66 million Americans. Moreover, atrial fibrillation is associated with a 1.5 to 1.9-fold higher risk of death due to its strong correlation with thromboembolic events. Because of the attributed increased morbidity and mortality, challenges that concern identification of patients at risk for thromboembolic events from atrial fibrillation must be addressed. These challenges include compliance to pe...
Source: The American Journal of Cardiology - August 1, 2013 Category: Cardiology Authors: Chris Cannon, Michael D. Ezekowitz, Christopher Granger Tags: Multimedia Activities Source Type: research
Comparison by Meta-Analysis of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With a Mean Age of ≥70 Years
A paucity of published data evaluating the outcomes of older patients (age ≥70 years) undergoing revascularization for unprotected left main coronary artery disease is available. We performed aggregate data meta-analyses of the clinical outcomes (all-cause mortality, nonfatal myocardial infarction, stroke, repeat revascularization, and major adverse cardiac and cerebrovascular events at 30 days and 12 and 22 months) in studies comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with a mean age of ≥70 years and unprotected left main coronary artery disease. A compre...
Source: The American Journal of Cardiology - May 31, 2013 Category: Cardiology Authors: Mahboob Alam, Salim S. Virani, Saima A. Shahzad, Sahar Siddiqui, Khaleeq H. Siddiqui, Shahzad A. Mumtaz, Neal S. Kleiman, Joseph S. Coselli, Nasser M. Lakkis, Hani Jneid Tags: Coronary Artery Disease Source Type: research
Usefulness of Local Delivery of Thrombolytics Before Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (the Delivery of Thrombolytics Before Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention DISSOLUTION Randomized Trial)
In conclusion, local, intrathrombus delivery of thrombolytics before manual thrombectomy improved the postprocedural coronary flow and myocardial perfusion and the 6-month clinical outcomes.
Source: The American Journal of Cardiology - May 28, 2013 Category: Cardiology Authors: Cesare Greco, Francesco Pelliccia, Gaetano Tanzilli, Maria Denitza Tinti, Paola Salenzi, Cristina Cicerchia, Michele Schiariti, Ferdinando Franzoni, Giuseppe Speziale, Pietro Gallo, Carlo Gaudio Tags: Coronary Artery Disease Source Type: research
Efficacy of the CHADS2 Scoring System to Assess Left Atrial Thrombogenic Milieu Risk Before Cardioversion of Non-Valvular Atrial Fibrillation
In this study, data from 2,369 consecutive patients in whom transesophageal echocardiography was performed for screening before direct-current cardioversion from 1999 to 2008 were analyzed. Left atrial (LA) or LA appendage (LAA) thrombogenic milieu (spontaneous echo contrast, sludge, and thrombus) was investigated. The results were correlated with CHADS2 score findings. The mean age was 66 ± 13 years, and the ratio of men to women was 2.2:1. CHADS2 scores of 0, 1, 2, 3, 4, 5 and 6 were present in 11%, 25%, 30%, 22%, 8%, 3%, and 1% of the studies, respectively. The prevalence of LA or LAA sludge or thrombus increased with ...
Source: The American Journal of Cardiology - May 31, 2013 Category: Cardiology Authors: Hirad Yarmohammadi, Tristan Klosterman, Gaganpreet Grewal, M. Chadi Alraies, Brandon C. Varr, Bruce Lindsay, Andrew O. Zurick, Kevin Shrestha, W.H. Wilson Tang, Mandeep Bhargava, Allan L. Klein Tags: Arrhythmias and Conduction Disturbances Source Type: research
Angina Pectoris or Myocardial Infarctions, Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, and Paradoxical Emboli
In conclusion, we suggest that in patients with untreated PAVMs, cardiac ischemia can occur because of a paradoxical embolus through PAVMs to a coronary artery.
Source: The American Journal of Cardiology - May 23, 2013 Category: Cardiology Authors: Katherine Clark, Reed E. Pyeritz, Scott O. Trerotola Tags: Miscellaneous Source Type: research
Relation of Subclinical Coronary Artery Atherosclerosis to Cerebral White Matter Disease in Healthy Subjects From Families With Early-Onset Coronary Artery Disease
White matter disease (WMD) of the brain is associated with incident stroke. Similarly, subclinical calcified coronary artery plaque has been associated with incident coronary artery disease (CAD) events. Although atherogenesis in both vascular beds may share some common mechanisms, the extent to which subclinical CAD is associated with WMD across age ranges in subjects with a family history of early-onset CAD remains unknown. We screened 405 apparently healthy participants in the Genetic Study of Atherosclerotic Risk for CAD risk factors and for the presence of noncalcified and calcified coronary plaque using dual-source m...
Source: The American Journal of Cardiology - June 5, 2013 Category: Cardiology Authors: Brian G. Kral, Paul Nyquist, Dhananjay Vaidya, David Yousem, Lisa R. Yanek, Elliot K. Fishman, Lewis C. Becker, Diane M. Becker Tags: Coronary Artery Disease Source Type: research
