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Source: The American Journal of Cardiology

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Total 715 results found since Jan 2013.

Relation of the CHA2DS2-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities ARIC Study)
Recent hospital-based cohort studies found the CHA2DS2-VASc score to be associated with ischemic stroke in individuals without atrial fibrillation (AF). Our aim was to determine the distribution of embolic and thrombotic strokes and association with the CHA2DS2-VASc score, among community-dwelling individuals without AF. We included participants from the Atherosclerosis Risk in Communities (ARIC) Study who attended visit 4 (1996-98) and had no prior AF, stroke, or anticoagulant use (n=10,671). During follow-up through 2008, incident AF cases (n=760) and participants who started warfarin were censored.
Source: The American Journal of Cardiology - November 6, 2018 Category: Cardiology Authors: Ryan J. Koene, M. Chadi Alraies, Faye L. Norby, Elsayed Z. Soliman, Ankit Maheshwari, Gregory Y.H. Lip, Alvaro Alonso, Lin Y. Chen Source Type: research

Comparison of Frequency of Ischemic Stroke in Patients With Versus Without Coronary Heart Disease and Without Atrial Fibrillation
We examined ischemic stroke risk in patients without atrial fibrillation who underwent coronary angiography between 2004 and 2012. Patients were stratified according to presence or absence of CAD and further stratified by extent of CAD (0 vessel disease [VD], 1 VD, 2 VD, 3 VD, and diffuse VD).
Source: The American Journal of Cardiology - October 30, 2018 Category: Cardiology Authors: Kevin Kris Warnakula Olesen, Kamilla Steensig, Morten Madsen, Troels Thim, Lisette Okkels Jensen, Bent Raungaard, John Eikelboom, Steen Dalby Kristensen, Hans Erik B øtker, Michael Maeng Source Type: research

Relation of Platelet Parameters with Incident Cardiovascular Disease (The Dongfeng-Tongji Cohort Study)
This study aimed to investigate the above-mentioned prospective relations in the middle-aged and older Chinese populations based on the Dongfeng-Tongji (DFTJ) cohort. We included 31,751 participants who were free of coronary heart disease (CHD), stroke, cancer, or severely abnormal electrocardiogram (ECG) at baseline.
Source: The American Journal of Cardiology - October 23, 2018 Category: Cardiology Authors: Shiqi He, Wenhui Lei, Jun Li, Kuai Yu, Yanqiu Yu, Lue Zhou, Xiaomin Zhang, Meian He, Huan Guo, Handong Yang, Tangchun Wu Source Type: research

Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20-years (from the Atherosclerosis Risk in Communities ARIC Study)
Resting heart rate (RHR) is independently associated with cardiovascular disease (CVD) risk. We determined whether RHR, measured in mid-life, is also associated with cognitive decline. We studied 13,720 middle-aged white and black ARIC participants without a prior history of stroke or atrial fibrillation. RHR was obtained from a 12-lead resting electrocardiogram at the baseline visit (1990-1992) and categorized into groups as
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Stephanie Wang, Oluwaseun E. Fashanu, Di Zhao, Eliseo Guallar, Rebecca F. Gottesman, Andrea L.C. Schneider, John W. McEvoy, Faye L. Norby, Amer I. Aladin, Alvaro Alonso, Erin D. Michos Source Type: research

Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities ARIC Study)
Resting heart rate (RHR) is independently associated with cardiovascular disease (CVD) risk. We determined whether RHR, measured in mid-life, is also associated with cognitive decline. We studied 13,720 middle-aged white and black ARIC participants without a history of stroke or atrial fibrillation. RHR was obtained from a 12-lead resting electrocardiogram at the baseline visit (1990 to 1992) and categorized into groups as
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Stephanie Wang, Oluwaseun E. Fashanu, Di Zhao, Eliseo Guallar, Rebecca F. Gottesman, Andrea L.C. Schneider, John W. McEvoy, Faye L. Norby, Amer I. Aladin, Alvaro Alonso, Erin D. Michos Source Type: research

Usefulness of the Echocardiographic Calcium Score to Refine Risk of Major Adverse Cardiovascular Events Beyond the Traditional Framingham Risk Score
Echocardiographic calcifications are associated with major adverse cardiovascular events (MACE). A recently described semi-quantitative Global Cardiac Calcium Score (GCCS) has been associated with mortality and stroke, with increasing scores associated with increasing risk. This score assigns points for calcium in the aortic root and valve, mitral valve and annulus, and submitral apparatus, with additional points for restricted leaflet mobility. We tested the hypothesis that the GCCS could improve prediction of MACE beyond traditional risk scores.
Source: The American Journal of Cardiology - October 18, 2018 Category: Cardiology Authors: Parasuram Krishnamoorthy, Shuchita Gupta, Marvin Lu, Evan J. Friend, Gregg S. Pressman Source Type: research

Relation of CHA2DS2VASC Score with Hemorrhagic Stroke and Mortality in Patients Undergoing Fibrinolytic Therapy for ST Elevation Myocardial Infarction
Hemorrhagic stroke (HS) is a feared complication of Fibrinolytic therapy (FT). Risk assessment scores may help in risk stratification to reduce this complication. Patients (admissions) ≥18 years with a primary diagnosis of STEMI who received systemic thrombolysis were extracted from Nationwide Inpatient Sample database and stratified and compared based on CHA2DS2VASC score 0-3, 4-6 and 7-9 as low, intermediate and high risk respectively. The primary outcomes of interest were hem orrhagic stroke (HS) and mortality.
Source: The American Journal of Cardiology - October 18, 2018 Category: Cardiology Authors: Gbolahan O. Ogunbayo, Robert Pecha, Naoki Misumida, Dustin Hillerson, Ayman Elbadawi, Ahmed Abdel-latif, Claude S. Elayi, Adrian W. Messerli, Susan S. Smyth Source Type: research

Temporal-Trends in Sex-Related Differences and Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation (From the Israeli TAVI Multicentre Registry)
We evaluated temporal trends in sex-related differences in patients undergoing trans-catheter aortic valve implantation (TAVI) for severe symptomatic aortic stenosis (AS) from a multicentre TAVI registry during the years 2008-2016. Our final cohort included 1,159 males and 1,370 females, with a median follow-up of 2.3 (IQR 1.2, 4.4) years. For temporal trends analysis, the entire population was divided according to period of procedure: 2008-2012 and 2013-2016. During the 2008-2012 period, the rates of in-hospital aortic paravalvular leak, myocardial infarction, pacemaker implantation, and stroke were higher among males tha...
Source: The American Journal of Cardiology - October 3, 2018 Category: Cardiology Authors: Osnat Itzhaki Ben Zadok, Ran Kornowski, Ariel Finkelstein, Israel Barbash, Haim Danenberg, Amit Segev, Victor Guetta, Amir Halkin, Hana Vaknin, David Planer, Abid Assali, Alon Barsheshet, Katia Orvin Source Type: research

Temporal Trends in Gender-Related Differences and Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the Israeli Transcatheter Aortic Valve Implantation Multicenter Registry)
We evaluated temporal trends in gender-related differences in patients who underwent transcatheter aortic valve implantation (TAVI) for severe symptomatic aortic stenosis from a multicenter TAVI registry during the years 2008 to 2016. Our final cohort included 1,159 males and 1,370 females, with a median follow-up of 2.3 (IQR 1.2, 4.4) years. For temporal trends analysis, the entire population was divided according to period of procedure: 2008 to 2012 and 2013 to 2016. During the 2008 to 2012 period, the rates of in-hospital aortic paravalvular leak, myocardial infarction, pacemaker implantation, and stroke were higher amo...
Source: The American Journal of Cardiology - October 3, 2018 Category: Cardiology Authors: Osnat Itzhaki Ben Zadok, Ran Kornowski, Ariel Finkelstein, Israel Barbash, Haim Danenberg, Amit Segev, Victor Guetta, Amir Halkin, Hana Vaknin, David Planer, Abid Assali, Alon Barsheshet, Katia Orvin Source Type: research

Prevalence and Resolution of Left Atrial Thrombus in Patients With Nonvalvular Atrial Fibrillation and Flutter With Oral Anticoagulation
This study sought to establish 1) the prevalence of LAA thrombus 2) the prevalence of LAA thrombus despite antithrombotic therapy, 3) the rate of persistence of LAA thrombus despite appropriate anticoagulant prescriptions, and 4) determinants of LAA thrombus persistence.
Source: The American Journal of Cardiology - September 26, 2018 Category: Cardiology Authors: Adam D Niku, Takahiro Shiota, Robert J Siegel, Florian Rader Source Type: research

Thoracoscopic Left Atrial Appendage Occlusion for Stroke Prevention Compared with Long-Term Warfarin Therapy in Patients With Nonvalvular Atrial Fibrillation
Thoracoscopic left atrial appendage (LAA) occlusion is an alternative treatment for stroke prevention in patients with atrial fibrillation. Prospective study comparing thoracoscopic LAA occlusion and warfarin therapy is still lacking. The goal of this prospective cohort study was to assess the safety and efficacy of thoracoscopic LAA occlusion for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF) compared with long-term warfarin therapy. 492 NVAF Patients were enrolled. 257 patients were treated with thoracoscopic LAA occlusion and 235 with long-term warfarin therapy.
Source: The American Journal of Cardiology - September 26, 2018 Category: Cardiology Authors: Mingjie Fu, Zheng Qin, Shuai Zheng, Yueping Li, Shiwei Yang, Yingxin Zhao, Chengping Hu, Kuo Zhou, Yujie Zhou, Xu Meng Source Type: research

Comparison of the Utility of Transesophageal Echocardiography in Patients With Acute Ischemic Stroke and Transient Ischemic Attack Stratified by Age Group ( < 60, 60-80, ≥80 Years)
The objective was to study the utility of transesophageal echocardiography (TEE) in affecting acute ischemic stroke treatment of older adults (age, ≥80 years). Patients hospitalized between January 2010 and February 2015 were included who had TEE ordered as part of their diagnostic workup at a tertiary medical center. We studied 515 hospitalized patients with acute stroke or transient ischemic attack who underwent TEE. The proportion of patie nts with important TEE findings was 35%. However, TEE changed management in only 2.5% of cases.
Source: The American Journal of Cardiology - September 17, 2018 Category: Cardiology Authors: Ryan C. Van Woerkom, Steven J. Lester, Bart M. Demaerschalk, Austin J. LaBanc, Megan L. Davis, Maria F. Coakley, Stephen S. Cha, Susan Wilansky Tags: Original Article Source Type: research

Meta-Analysis comparing Outcomes of Drug Eluting Stents versus Single and Multi-Arterial Coronary Artery Bypass Grafting
Relative benefits of coronary artery bypass (CABG) using single and multiple arterial grafting (SAG, MAG) and drug eluting stent (DES) in multivessel coronary disease remain uncertain. We compared SAG, MAG and DES in a pairwise and network meta-analysis. Randomized trials and adjusted observational studies comparing CABG versus DES were included (primary endpoint: long-term mortality; secondary endpoints: operative mortality, perioperative stroke and follow-up repeated revascularization [RR]). Studies with ≥1.7arterial grafts/patient were classified as MAG.
Source: The American Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Mario Gaudino, Mohamed Rahouma, Ahmed Abouarab, Derrick Y Tam, Antonino Di Franco, Jeremy Leonard, Umberto Benedetto, Mario Iannaccone, Fabrizio D'Ascenzo, Giuseppe Biondi-Zoccai, Michael Vallely, Leonard N Girardi, Stephen E Fremes, David P Taggart Source Type: research

Underuse of oral anticoagulants in patients with ischemic stroke and atrial fibrillation in China
Anticoagulant therapy is an effective stroke prevention measure for people with atrial fibrillation (AF) who are at high risk of ischemic stroke. However, it is reported that oral anticoagulants (OACs) are generally underused in clinical practice. A better awareness of current usage of anticoagulant therapy would enable prevention of stroke secondary to AF. Therefore, we determined the nationwide prevalence of AF and the frequency of OACs use among patients with ischemic stroke in China. Based on the China National Stroke Screening Survey (CNSSS), a representative nationwide sample of 1,252,703 adults over 40 years old dur...
Source: The American Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Jian Guo, Tianjia Guan, Siyuan Fan, Baohua Chao, Longde Wang, Yuanli Liu Source Type: research

Meta-Analysis Comparing Outcomes of Drug Eluting Stents Versus Single and Multiarterial Coronary Artery Bypass Grafting
Relative benefits of coronary artery bypass (CABG) using single and multiple arterial grafting (SAG, MAG) and drug eluting stent (DES) in multivessel coronary disease remain uncertain. We compared SAG, MAG, and DES in a pairwise and network meta-analysis. Randomized trials and adjusted observational studies comparing CABG versus DES were included (primary end point: long-term mortality; secondary end points: operative mortality, perioperative stroke, and follow-up repeated revascularization [RR]).
Source: The American Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Mario Gaudino, Mohamed Rahouma, Ahmed Abouarab, Derrick Y Tam, Antonino Di Franco, Jeremy Leonard, Umberto Benedetto, Mario Iannaccone, Fabrizio D'Ascenzo, Giuseppe Biondi-Zoccai, Michael Vallely, Leonard N Girardi, Stephen E Fremes, David P Taggart Source Type: research