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Source: The American Journal of Cardiology
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Total 715 results found since Jan 2013.
Relation of Obesity to Outcomes of Hospitalizations for Atrial Fibrillation
Obesity has been linked with increased incidence of atrial fibrillation (AF), but impact of presence of obesity on outcomes of hospitalizations for AF has not been investigated. We used the National Inpatient Sample (NIS) database 2010-2014 to identify all adult hospitalizations aged ≥18 years with a primary diagnosis of AF. Obese patients were identified using the co-morbidity variable for obesity, as defined in NIS databases. Multivariable logistic regression was used to compare in-hospital outcomes (mortality, acute stroke events) between obese and non-obese patients with A F.
Source: The American Journal of Cardiology - February 14, 2019 Category: Cardiology Authors: Manyoo A. Agarwal, Lohit Garg, Mahek Shah, Brijesh Patel, Nidhi Jain, Sameer Jain, Rajesh Kabra, Csaba Kovesdy, Guy L. Reed, Carl J. Lavie Source Type: research
Sex Differences in Risk Factors for Incident Atrial Fibrillation (From the Reasons for Geographic And Racial Differences in Stroke (REGARDS) Study)
We examined whether the sex differences in atrial fibrillation (AF) is related to difference in risk factors leading to AF or due to a differential impact of the same risk factors in 11,806 participants (55.2 % women) from the REGARDS study. Incident AF was ascertained by electrocardiograms and medical history at a follow-up examination. Backwards elimination logistic regression was used to identify AF risk factors in men and women, separately. Over a median follow-up of 9.0 years, 588 (11.1%) men and 428 (6.6%) women (p-value
Source: The American Journal of Cardiology - February 9, 2019 Category: Cardiology Authors: Abhishek Bose, Wesley T. O'Neal, Chengyi Wu, Leslie A. McClure, Suzanne E. Judd, Virginia J. Howard, George Howard, Elsayed Z. Soliman Source Type: research
Thoracoscopic Left Atrial Appendage Occlusion for Stroke Prevention Compared with Long-Term Warfarin Therapy in Patients With Nonvalvular Atrial Fibrillation
In their recent paper, Fu et al. conclude that thoracoscopic left atrial appendage (LAA) occlusion is superior to warfarin for a composite outcome of stroke, systemic embolism and mortality.1 We suggest considering their results with caution.
Source: The American Journal of Cardiology - February 8, 2019 Category: Cardiology Authors: Sophie Weiwei Gao, Emilie Prudence Belley-C ôté, Kevin John Um, Richard Paul Whitlock Tags: Reader's Comments Source Type: research
Relation of Left Atrial Appendage Morphology Determined by Computed Tomography to Prior Stroke or to Increased Risk of Stroke in Patients With Atrial Fibrillation
This study aimed to assess inter-observer and intra-observer agreements in LAA morphology and its real value in stroke prediction. A total of 2264 atrial fibrillation (AF) patients who underwent computed tomography (CT) to explore the LAA anatomy were enrolled.
Source: The American Journal of Cardiology - January 23, 2019 Category: Cardiology Authors: Lingmin Wu, Erpeng Liang, Siyang Fan, Lihui Zheng, Zhongpeng Du, Shangyu Liu, Feng Hu, Xiaohan Fan, Gang Chen, Ligang Ding, Yan Yao Source Type: research
Relation of Admission Blood Pressure to In-hospital and 90-Day Outcomes in Patients Presenting with Transient Ischemic Attack
The association between admission blood pressure (BP) and outcomes in patients with transient ischemic attack (TIA) is not well defined. Patients in the United States national Get With The Guidelines-Stroke registry with a TIA were included. Admission systolic and diastolic BP was used to compute mean arterial pressure (MAP) and pulse pressure (PP). A subset of this cohort was linked to CMS claims data for post-discharge outcomes. The in-hospital outcomes of interest were: mortality, not discharged home, and inability to ambulate independently at discharge.
Source: The American Journal of Cardiology - January 10, 2019 Category: Cardiology Authors: Sripal Bangalore, Lee Schwamm, Eric E. Smith, Anne S. Hellkamp, Ying Xian, Phillip J. Schulte, Jeffrey L. Saver, Gregg C. Fonarow, Deepak L. Bhatt, for the Get With The Guidelines-Stroke Steering Committee and Investigators Source Type: research
Extremely low prevalence of Takotsubo cardiomyopathy and transient cardiac dysfunction in stroke patients with T-wave abnormalities
Stone et al. studied an important association about the presence of cerebral T-waves in 800 patients with ischemic stroke1. They demonstrated that about 17 (2.1%) patients presenting with stroke exhibited cerebral T-waves and of those, only 3 patients (18%) with T-wave abnormality have transient systolic dysfunction on echocardiography. Thus overall, only 0.0037% (3 of 800) patients developed Takotsubo cardiomyopathy (TC) in the study group of patients with stroke.1
Source: The American Journal of Cardiology - January 9, 2019 Category: Cardiology Authors: Lovely Chhabra, Nauman Khalid, Pooja Sareen Source Type: research
Incidence, Predictors, Management, and Clinical Significance of New-Onset Atrial Fibrillation After Transcatheter Aortic Valve Implantation
There is limited information on the incidence, management, and prognostic impact of new-onset atrial fibrillation (NOAF) following transcatheter aortic valve implantation (TAVI) for severe aortic valve stenosis (AS). In the prospective ASAN-TAVI registry, we evaluated a total of 347 consecutive patients who underwent TAVI between March 2010 and August 2017. The primary endpoint was a composite of stroke or systemic embolism at 12 months. The study subjects were categorized into 3 groups; pre-existing AF (50 patients), NOAF (31 patients), and non-AF (266 patients) group.
Source: The American Journal of Cardiology - January 4, 2019 Category: Cardiology Authors: Yong-Hoon Yoon, Jung-Min Ahn, Do-Yoon Kang, Euihong Ko, Pil Hyung Lee, Seung-Whan Lee, Ho Jin Kim, Joon Bum Kim, Suk Jung Choo, Duk-Woo Park, Seung-Jung Park Source Type: research
Meta-analysis of Stroke and Bleeding Risk in Patients with Various Atrial Fibrillation Patterns Receiving Oral Anticoagulants
Oral anticoagulation therapy (OAT) is a mainstay for stroke prevention in atrial fibrillation (AF) patients. However, whether the risks of stroke/systemic embolic events (SEE) and bleeding events are affected by the type, duration, and frequency of AF in patients receiving OAT has been previously debated. We aimed to determine the risk of stroke/SEE and bleeding events associated with paroxysmal AF compared to persistent or permanent AF among patients who received OAT. Comprehensive literature searches of the Cochrane Library, PubMed/MEDLINE, and EMBASE databases were conducted from inception to July 2018.
Source: The American Journal of Cardiology - December 19, 2018 Category: Cardiology Authors: Weifang Zhang, Youwen Xiong, Lingling Yu, Aizhen Xiong, Huihui Bao, Xiaoshu Cheng Source Type: research
Relation of Body Mass Index to Risk of Death or Stroke in Patients Who Underwent Transcatheter Aortic Valve Implantation
Obesity and overweight have been associated with better clinical outcomes in different populations with a diverse spectrum of cardiovascular disease (obesity paradox). However, conflicting data exist about the relation between body mass index (BMI) and outcomes after transcatheter aortic valve implantation (TAVI). The aim of this study is to evaluate the association of body mass index with clinical outcomes in patients with severe aortic stenosis (AS) who underwent TAVI. The study cohort included 379 consecutive patients with symptomatic severe AS who underwent TAVI between March 2010 and February 2017 in 3 centers in East Asia.
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: Sang Yong Om, Euihong Ko, Jung-Min Ahn, Do-Yoon Kang, Kyusup Lee, Osung Kwon, Pil Hyung Lee, Seung-Whan Lee, Ho Jin Kim, Joon Bum Kim, Suk Jung Choo, Duk-Woo Park, Seung-Jung Park Source Type: research
Relation of Race, Apparent Disability, and Stroke Risk With Warfarin Prescribing for Atrial Fibrillation in Patients Receiving Maintenance Hemodialysis
We examined patterns of warfarin use, and associated factors, after AF diagnosis. This retrospective cohort analysis studied US Medicare patients receiving maintenance dialysis January 1, 2008-June 30, 2010. Demographics, comorbidity, and a durable medical equipment claims-based disability proxy score predicted warfarin prescription after AF diagnosis. The analysis included 8964 patients with non-valvular AF.
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: James B. Wetmore, Yi Peng, David T. Gilbertson, Jiannong Liu Source Type: research
Impact of Body Mass Index on Outcomes in the Edoxaban Versus Warfarin Therapy Groups in Patients Undergoing Cardioversion of Atrial Fibrillation (From ENSURE-AF)
In the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study (NCT 02072434), edoxaban showed similar efficacy and safety vs enoxaparin –warfarin in patients undergoing electrical cardioversion of nonvalvular atrial fibrillation. In this ancillary analysis, we compared the primary efficacy (composite of stroke, systemic embolic event, myocardial infarction, and cardiovascular [CV] death, overall study period) and safety (composite of major and clinically relevant nonmajor [CRNM] bleeding, on-treatment) endpoints in relation to body mass index (BMI;
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: Gregory Y.H. Lip, Jose L. Merino, Maciej Banach, Joris R. de Groot, Lars S. Maier, Sakis Themistoclakis, Giuseppe Boriani, James Jin, Michael Melino, Shannon M. Winters, Andreas Goette Source Type: research
Relation of Body-Mass Index to Risk of Death or Stroke Among Patients Undergoing Transcatheter Aortic Valve Implantation
Obesity and overweight have been associated with better clinical outcomes in different populations with a diverse spectrum of cardiovascular disease ( “obesity paradox”). However, conflicting data exist about the relation between BMI and outcomes after transcatheter aortic valve implantation (TAVI). The aim of this study is to evaluate the association of body mass index (BMI) with clinical outcomes in patients with severe aortic stenosis (AS) undergoing TAVI. The study cohort included 379 consecutive patients with symptomatic severe AS who underwent TAVI between March 2010 and February 2017 in 3 centers in East Asia.
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: Sang Yong Om, Euihong Ko, Jung-Min Ahn, Do-Yoon Kang, Kyusup Lee, Osung Kwon, Pil Hyung Lee, Seung-Whan Lee, Ho Jin Kim, Joon Bum Kim, Suk Jung Choo, Duk-Woo Park, Seung-Jung Park Source Type: research
Relation of Venous Thromboembolism Risk to Ischemic Stroke Risk in Hospitalized Patients with Cancer
Patients with cancer are at increased risk for venous thromboembolism (VTE). However, the relationship of cancer type to the risk of arterial thrombosis in patients with high VTE risk has not been described. The goal of this study is to determine the rate of arterial thrombosis in patients with different types of solid tumors stratified by VTE risk. Using the 2012 National Inpatient Sample, we identified 373,789 hospitalizations involving patients ≥18 years associated with solid tumors, stratified by type.
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: Alyssa M. Corley, Malachy J. Sullivan, Scott E. Friedman, Daniel J. O'Rourke, Robert T. Palac, Anthony S. Gemignani Source Type: research
Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
The objective of this study was to evaluate the impact of heart failure (HF) etiology (ischemic cardiomyopathy [ICM] versus nonischemic cardiomyopathy) on in-hospital outcomes in patients undergoing left ventricular assist device (LVAD) placement using the Nationwide Inpatient Sample database. We identified patients who underwent LVAD placement from 2011 to 2014. The primary end point was the effect of ICM on in-hospital mortality. Secondary end points included periprocedural vascular complications requiring surgery, postoperative myocardial infarction, stroke, and hemorrhage requiring transfusion.
Source: The American Journal of Cardiology - November 20, 2018 Category: Cardiology Authors: Hossam Abubakar, Ahmed Subahi, Oluwole Adegbala, Ahmed S. Yassin, Emmanuel Akintoye, Ahmed Abdulrahman, Abdelrahman Ahmed, Adedotun Alade, Mohit Pahuja, Luis Afonso Source Type: research
Comparison of In-hospital Outcomes of Patients With-vs-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
The objective of this study was to evaluate the impact of heart failure (HF) etiology (ischemic cardiomyopathy (IC) vs. non-ischemic cardiomyopathy (NIC)) on in-hospital outcomes in patients undergoing left ventricular assist device (LVAD) placement using the Nationwide Inpatient Sample (NIS) database. We identified patients who underwent LVAD placement from 2011 to 2014. The primary endpoint was the effect of ICM on in-hospital mortality. Secondary endpoints included peri-procedural vascular complications requiring surgery, post-operative myocardial infarction, stroke and hemorrhage requiring transfusion.
Source: The American Journal of Cardiology - November 20, 2018 Category: Cardiology Authors: Hossam Abubakar, Ahmed Subahi, Oluwole Adegbala, Ahmed S Yassin, Emmanuel Akintoye, Ahmed Abdulrahman, Abdelrahman Ahmed, Adedotun Alade, Mohit Pahuja, Luis Afonso Source Type: research
