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Source: The American Journal of Cardiology

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Total 715 results found since Jan 2013.

Drug-eluting Stents Versus Bypass Surgery for Left Main Disease: An updated meta-analysis of randomized controlled trials with long-term follow-up
Debate is ongoing regarding the optimal mode of revascularization for patients with left main coronary artery disease (LMCAD). Longer-term follow-up from randomized trials has recently become available. We recently published a study-level meta-analysis that demonstrated similar mortality after percutaneous coronary intervention (PCI) with drug-eluting stents (DES) when compared with coronary artery bypass grafting (CABG) 1. There were also no differences in cardiac death, stroke or myocardial infarction (MI), although there was a greater risk of unplanned revascularization after PCI.
Source: The American Journal of Cardiology - June 29, 2020 Category: Cardiology Authors: Yousif Ahmad, James P. Howard, Ahran D. Arnold, Ziad A. Ali, Darrel Francis, Jeffrey W. Moses, Martin B. Leon, Ajay J. Kirtane, Dimitri Karmpaliotis, Gregg W. Stone Source Type: research

Propensity-Matched Comparison of Evolut-R Transcatheter Aortic Valve Implantation With Surgery in Intermediate-Risk Patients (from the SURTAVI Trial)
The Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI) trial demonstrated the noninferiority of transcatheter aortic valve implantation (TAVI) using a self-expanding bioprosthesis to surgical aortic valve replacement (SAVR) for the primary end point of all-cause mortality or disabling stroke at 2 years in patients with severe, symptomatic aortic stenosis at intermediate risk for surgery.1 The majority of TAVI patients in the SURTAVI trial (84%) received the first generation CoreValve bioprosthesis (Medtronic, Minneapolis, Minnesota).
Source: The American Journal of Cardiology - June 28, 2020 Category: Cardiology Authors: Steven J. Yakubov, Nicolas M. Van Mieghem, Michael J. Reardon, Patrick W. Serruys, Hemal Gada, Mubashir Mumtaz, G. Michael Deeb, Susheel Kodali, Isaac George, Stephan Windecker, Neal Kleiman, Stanley J. Chetcuti, Carlos Sanchez, Harold L. Dauerman, Shuzhe Source Type: research

Propensity-Matched Comparison of Evolut R Transcatheter Aortic Valve Implantation with Surgery in Intermediate-Risk Patients (From the SURTAVI Trial)
The Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI) trial demonstrated the noninferiority of transcatheter aortic valve implantation (TAVI) using a self-expanding bioprosthesis to surgical aortic valve replacement (SAVR) for the primary endpoint of all-cause mortality or disabling stroke at 2 years in patients with severe, symptomatic aortic stenosis at intermediate risk for surgery.1 The majority of TAVI patients in the SURTAVI trial (84%) received the first generation CoreValve bioprosthesis (Medtronic, Minneapolis, MN).
Source: The American Journal of Cardiology - June 28, 2020 Category: Cardiology Authors: Steven J. Yakubov, Nicolas M. Van Mieghem, Michael J. Reardon, Patrick W. Serruys, Hemal Gada, Mubashir Mumtaz, G. Michael Deeb, Susheel Kodali, Isaac George, Stephan Windecker, Neal Kleiman, Stanley J. Chetcuti, Carlos Sanchez, Harold L. Dauerman, Shuzhe Source Type: research

Impact of Diabetes Mellitus on Stroke and Survival in Patients with Atrial Fibrillation
Although diabetes mellitus (DM) has been established as a risk factor for developing atrial fibrillation (AF) and is a known risk factor for stroke, it is unclear whether the presence or duration of DM is the primary adverse influence on the clinical course of AF. We retrospectively analyzed patients diagnosed with incident AF to examine the impact of DM on ischemic stroke and all-cause mortality. The diagnosis of DM was established by ICD-9 codes and review of medical records. To account for the significant differences in baseline characteristics of patients with and without diabetes, we matched 909 AF patients with DM wi...
Source: The American Journal of Cardiology - June 28, 2020 Category: Cardiology Authors: Sri Harsha Patlolla, Hon-Chi Lee, Peter A. Noseworthy, Waldemar E. Wysokinski, David O. Hodge, Eddie L. Greene, Bernard J. Gersh, Rowlens M. Melduni Source Type: research

Assessment of ST-Segment Elevation Myocardial Infarction Volume Trends During The COVID-19 Pandemic
Routine inpatient and outpatient health care has been greatly disrupted by the COVID-19 pandemic and both equipment and personnel have been redeployed in order to manage the crisis (https://www.cms.gov/newsroom/press-releases/cms-releases-recommendations-adult-elective-surgeries-non-essential-medical-surgical-and-dental). There have been anecdotal accounts (https://www.nytimes.com/2020/04/06/well/live/coronavirus-doctors-hospitals-emergency-care-heart-attack-stroke.html) and a publication (1) discussing the decrease in the number of ST-segment elevation myocardial infarction (STEMI) activiations.
Source: The American Journal of Cardiology - June 26, 2020 Category: Cardiology Authors: Amir S Lotfi, Alina Capatina, Aaron D Kugelmass Source Type: research

Reader's CommentsAssessment of ST-Segment Elevation Myocardial Infarction Volume Trends During The COVID-19 Pandemic
Routine inpatient and outpatient health care has been greatly disrupted by the COVID-19 pandemic and both equipment and personnel have been redeployed in order to manage the crisis (https://www.cms.gov/newsroom/press-releases/cms-releases-recommendations-adult-elective-surgeries-non-essential-medical-surgical-and-dental). There have been anecdotal accounts (https://www.nytimes.com/2020/04/06/well/live/coronavirus-doctors-hospitals-emergency-care-heart-attack-stroke.html) and a publication 1 discussing the decrease in the number of ST-segment elevation myocardial infarction (STEMI) activiations.
Source: The American Journal of Cardiology - June 26, 2020 Category: Cardiology Authors: Amir S Lotfi, Alina Capatina, Aaron D Kugelmass Source Type: research

A Novel Model for Prediction of Thromboembolic and Cardiovascular Events in Patients without Atrial Fibrillation
Patients without atrial fibrillation (AF) constitute approximately 75% of patients with thromboembolic events (TE: ischemic stroke, transient ischemic attack (TIA), and systemic embolism)1 but evidence supporting risk stratification and prophylactic treatment in these patients is sparse. The latter may be explained by the lack of an intervention that, beyond treatment of hypertension and cholesterol, reduces TE risk in patients without AF. However, the COMPASS (Cardiovascular Outcomes for People Using Anticoagulation Strategies) trial, that almost exclusively included patients without AF, showed that the combination of asp...
Source: The American Journal of Cardiology - June 26, 2020 Category: Cardiology Authors: Kamilla Steensig, Kevin K W Olesen, Morten Madsen, Troels Thim, Lisette Okkels Jensen, Morten W ürtz, Steen Dalby Kristensen, Hans Erik Bøtker, Gregory Y H Lip, John William Eikelboom, Michael Maeng Source Type: research

Comparison of Oral Anticoagulant Use and Stroke Risk among Older Adults Newly-Diagnosed Atrial Fibrillation Living in Urban-vs-Rural Areas
We aimed to assess the association between urban/rural residence and the risk of ischemic stroke in individuals with newly diagnosed atrial fibrillation (AF), and to quantify the role of oral anticoagulation (OAC) initiation in the variation in stroke risk between urban and rural residents with AF. Using 5% random samples of Medicare claims, we identified fee-for-service beneficiaries who were diagnosed with AF between January 2014 and December 2015. Beneficiaries were followed for 1 year since their AF diagnosis, and were categorized according to their initiation of OAC within the year.
Source: The American Journal of Cardiology - June 15, 2020 Category: Cardiology Authors: Jingchuan Guo, Meiqi He, Jared W Magnani, Maria M Brooks, Walid F. Gellad, Inmaculada Hernandez Source Type: research

Meta-analysis Comparing Multiple Arterial Grafts versus Single Arterial Graft for Coronary-Artery Bypass Grafting
Observational studies and randomized controlled trials (RCTs) have shown conflicting outcomes for multiple arterial graft (MAG) coronary artery bypass graft surgery (CABG) compared to single arterial grafts (SAGs). The predominant evidence supporting the use of MAGs is observational. The aim of this meta-analysis of RCTs is to compare outcomes following MAG and SAG. We searched multiple databases for RCTs comparing MAG versus SAG. The clinical outcomes studied were all-cause mortality, cardiac mortality, myocardial infarction (MI), revascularization, stroke, sternal wound complications, and major bleeding.
Source: The American Journal of Cardiology - June 14, 2020 Category: Cardiology Authors: Khalid Changal, Saqib Masroor, Ahmed Elzanaty, Mitra Patel, Tanveer Mir, Shayan Khan, Salik Nazir, Ronak Soni, Carson Oostra, Sadik Khuder, Ehab Eltahawy Source Type: research

Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤ 50 Years of Age with Laboratory Confirmed COVID-19 Infection
The COVID-19 epidemic has led to an unpreceded disruption in health care systems worldwide. Concerns have been recently raised about young patients with COVID-19 presenting with large ischemic strokes.1 Data on stroke in COVID-19 patients remain limited to a few case reports.1 In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database.
Source: The American Journal of Cardiology - June 13, 2020 Category: Cardiology Authors: Frank Annie, Mark C. Bates, Aravinda Nanjundappa, Deepak L. Bhatt, Mohamad Alkhouli Source Type: research

Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤50 Years of Age With Laboratory Confirmed COVID-19 Infection
The COVID-19 epidemic has led to an unpreceded disruption in health care systems worldwide. Concerns have been recently raised about young patients with COVID-19 presenting with large ischemic strokes.1 Data on stroke in COVID-19 patients remain limited to a few case reports.1 In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database.
Source: The American Journal of Cardiology - June 13, 2020 Category: Cardiology Authors: Frank Annie, Mark C. Bates, Aravinda Nanjundappa, Deepak L. Bhatt, Mohamad Alkhouli Source Type: research

Baseline CHADS2 Score and Risk of Cardiovascular Events in the Population without Atrial Fibrillation
The association between CHADS2 score and stroke has been confirmed in patients with atrial fibrillation. But the majority of cardiovascular events occurred primarily in population without atrial fibrillation. Therefore, we performed this cohort study to evaluate the association between baseline CHADS2 score and cardiovascular events in the population without atrial fibrillation. A total of 99,755 Chinese adults with complete baseline data were followed for up to 10 years. The primary outcomes were cardiovascular event (a composite endpoint of myocardial infarction, cerebral infarction and cerebral hemorrhage) and all-cause death.
Source: The American Journal of Cardiology - June 2, 2020 Category: Cardiology Authors: Chunpeng Ji, Shouling Wu, Jihong Shi, Zhe Huang, ShuohuaChen, Guodong Wang, Wei Cui Source Type: research

Comparison of the Effect of Atrial Fibrillation Detection Algorithms in Patients with Cryptogenic Stroke Using Implantable Loop Recorders
Occult atrial fibrillation (AF) can be the underlying cause for cryptogenic stroke (CS). Implantable loop recorders (ILRs) have become an important tool for long-term arrhythmia monitoring in CS patients. Office-based ILR implantation by non-electrophysiologist physicians is increasingly common. To report the real world diagnostic yield and accuracy of remote ILR monitoring in high risk CS patients, we retrospectively analyzed 145 consecutive patients with CS who underwent ILR implantation between October 2014 and October 2018 at New York University Langone Health.
Source: The American Journal of Cardiology - May 21, 2020 Category: Cardiology Authors: Ehud Chorin, Connor Peterson, Edward Kogan, Chirag Barbhaiya, Anthony Aizer, Douglas Holmes, Scott Bernstein, Michael Schole, Harish Duraiswami, Michael Spinelli, David Park, Larry Chinitz, Lior Jankelson Source Type: research

Sleep Duration and Cardiovascular Disease Prevalence – The Debate Continues
We read with interest the study by Krittanawong et al “Sleep Duration and Cardiovascular Health in A Representative Community Population (from NHANES, 2005 to 2016)”.1 The authors studied 32,152 participants who responded to the sleep survey and found short sleep duration (9 hours) was also associated with higher prevalence of stroke, heart failure and coronary artery disease.
Source: The American Journal of Cardiology - May 18, 2020 Category: Cardiology Authors: Saurabh Aggarwal, Gaurav Aggarwal, Rohit Seth Loomba Source Type: research

Sleep Duration and Cardiovascular Disease Prevalence- the Debate Continues
We read with interest the study by Krittanawong et al “Sleep Duration and Cardiovascular Health in A Representative Community Population (from NHANES, 2005 to 2016)”.1 The authors studied 32,152 participants who responded to the sleep survey and found short sleep duration (9 hours) was also associated with higher prevalence of stroke, heart failure and coronary artery disease.
Source: The American Journal of Cardiology - May 18, 2020 Category: Cardiology Authors: Saurabh Aggarwal, Gaurav Aggarwal, Rohit Seth Loomba Source Type: research