Temporal-Trends in Sex-Related Differences and Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation (From the Israeli TAVI Multicentre Registry)

We evaluated temporal trends in sex-related differences in patients undergoing trans-catheter aortic valve implantation (TAVI) for severe symptomatic aortic stenosis (AS) from a multicentre TAVI registry during the years 2008-2016. Our final cohort included 1,159 males and 1,370 females, with a median follow-up of 2.3 (IQR 1.2, 4.4) years. For temporal trends analysis, the entire population was divided according to period of procedure: 2008-2012 and 2013-2016. During the 2008-2012 period, the rates of in-hospital aortic paravalvular leak, myocardial infarction, pacemaker implantation, and stroke were higher among males than females, but became comparable between the sexes during the 2013-2016 period.

Source: The American Journal of Cardiology - October 3, 2018 Category: Cardiology Authors: Osnat Itzhaki Ben Zadok, Ran Kornowski, Ariel Finkelstein, Israel Barbash, Haim Danenberg, Amit Segev, Victor Guetta, Amir Halkin, Hana Vaknin, David Planer, Abid Assali, Alon Barsheshet, Katia Orvin Source Type: research