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Total 27 results found since Jan 2013.

An Evidence-Based Review of Vitamin D for Common and High-Mortality Conditions
Conclusion: Prospective studies of vitamin D supplementation demonstrate variable impact on disease specific and patient-oriented outcomes, suggesting a correlation but not a causal relationship between low vitamin D levels and disease pathogenicity. Future research should determine dosing standards and timing of vitamin D in treatment and prevention.
Source: Journal of the American Board of Family Medicine - December 23, 2022 Category: Primary Care Authors: Michael, W., Couture, A. D., Swedlund, M., Hampton, A., Eglash, A., Schrager, S. Tags: Clinical Review Source Type: research

The Role of Depressive Disorders in Autonomic Cardiovascular Dysregulation in Fibromyalgia
This study investigated the role of comorbid depression in autonomic cardiovascular dysregulations in fibromyalgia. Methods Cardiovascular recordings were obtained in 53 participants with fibromyalgia who also had depression (n = 27), in participants with fibromyalgia without depression (n = 26), and in 29 healthy controls, at rest and during a cold pressor test and an arithmetic task. Assessed parameters included interbeat interval, blood pressure, heart rate variability, baroreflex sensitivity, stroke volume, preejection period, left ventricular ejection time, Heather index, and total peripheral resistance. Res...
Source: Psychosomatic Medicine - September 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Why Acupuncture Is Going Mainstream in Medicine
When the opioid addiction crisis began to surge in the U.S. about a decade ago, Dr. Medhat Mikhael spent a lot of time talking to his patients about other ways to heal pain besides opioids, from other types of medications to alternative treatments. As a pain management specialist at MemorialCare Orange Coast Medical Center in Fountain Valley, Calif., he didn’t anticipate leaving behind the short-term use of opioids altogether, since they work so well for post-surgical pain. But he wanted to recommend a remedy that was safer and still effective. That turned out to be acupuncture. “Like any treatment, acupuncture...
Source: TIME: Health - April 29, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate medicine Source Type: news

Comorbidities of primary headache disorders: a literature review with meta-analysis
ConclusionsSome of the most relevant comorbidities of primary headache disorders – back pain, anxiety and depression, diabetes, ischemic heart disease and stroke – are among the most burdensome conditions, together with headache themselves, according to the GBD study. A joint treatment of headaches and of these comorbidities may positively impact on headache sufferers’ hea lth status and contribute to reduce the impact of a group of highly burdensome diseases.
Source: The Journal of Headache and Pain - July 14, 2021 Category: Neurology Source Type: research

Neurological associations of SARS-CoV-2 infection: A Systematic Review
CNS Neurol Disord Drug Targets. 2021 Feb 16. doi: 10.2174/1871527320666210216121211. Online ahead of print.ABSTRACTBACKGROUND: The current ongoing COVID-19 pandemic has compelled us to scrutinize major outbreaks in the past two decades, severe acute respiratory syndrome (SARS), in 2002, and Middle East respiratory syndrome (MERS), in 2012. We aimed to assess the associated neurological manifestations with SARS CoV-2 infection.METHODS: In this systematic review, a search was carried out by key-electronic databases, controlled vocabulary, and indexing of trials to evaluate the available pertinent studies which included both ...
Source: CNS and Neurological Disorders Drug Targets - February 17, 2021 Category: Drugs & Pharmacology Authors: Amaan Javed Source Type: research

Neurological associations of SARS-CoV-2 infection: A Systematic Review.
Abstract BACKGROUND: The current ongoing COVID-19 pandemic has compelled us to scrutinize major outbreaks in the past two decades, severe acute respiratory syndrome (SARS), in 2002, and Middle East respiratory syndrome (MERS), in 2012. We aimed to assess the associated neurological manifestations with SARS CoV-2 infection. METHODS: In this systematic review, a search was carried out by key-electronic databases, controlled vocabulary, and indexing of trials to evaluate the available pertinent studies which included both medical subject headings (MeSH) and advance electronic databases comprising of PubMed, Emba...
Source: CNS and Neurological Disorders Drug Targets - February 16, 2021 Category: Drugs & Pharmacology Authors: Javed A Tags: CNS Neurol Disord Drug Targets Source Type: research

Impact of comorbid conditions on disease-specific quality of life in older men and women with atrial fibrillation
ConclusionsAmong older persons with AF, while cardiometabolic diseases were highly prevalent, musculoskeletal conditions exerted the greatest impact on patients ’ disease-specific QoL. Understanding the extent of impairment in QoL due to underlying comorbidities provides an opportunity to develop interventions targeted at diseases that may cause significant impairment in QoL.
Source: Quality of Life Research - July 10, 2020 Category: Health Management Source Type: research

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014-2018).
, Paulus W, Poulet E, Quartarone A, Rachid F, Rektorová I, Rossi S, Sahlsten H, Schecklmann M, Szekely D, Ziemann U Abstract A group of European experts reappraised the guidelines on the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) previously published in 2014 [Lefaucheur et al., Clin Neurophysiol 2014;125:2150-206]. These updated recommendations take into account all rTMS publications, including data prior to 2014, as well as currently reviewed literature until the end of 2018. Level A evidence (definite efficacy) was reached for: high-frequency (HF) rTMS of the primary motor corte...
Source: Clinical Neurophysiology - December 26, 2019 Category: Neurology Authors: Lefaucheur JP, Aleman A, Baeken C, Benninger DH, Brunelin J, Di Lazzaro V, Filipović SR, Grefkes C, Hasan A, Hummel FC, Jääskeläinen SK, Langguth B, Leocani L, Londero A, Nardone R, Nguyen JP, Nyffeler T, Oliveira-Maia AJ, Oliviero A, Padberg F, Palm Tags: Clin Neurophysiol Source Type: research

Lysophosphatidic Acid Receptor Signaling Underlying Chronic Pain and Neuroprotective Mechanisms through Prothymosin α.
Abstract For my Ph.D. research topic, I isolated endogenous morphine-like analgesic dipeptide, kyotorphin, which mediates Met-enkephalin release, and discovered kyotorphin synthetase, a putative receptor and antagonist. Furthermore, I succeeded in purifying μ-opioid receptor and functional reconstitution with purified G proteins. After receiving my full professor position at Nagasaki University in 1996, I worked on two topics of research, molecular mechanisms of chronic pain through lysophosphatidic acid (LPA) and identification and characterization of neuroprotective protein, prothymosin α. In a series of studi...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - November 8, 2019 Category: Drugs & Pharmacology Authors: Ueda H Tags: Yakugaku Zasshi Source Type: research

Outpatient burden of neurological disorders: A prospective evaluation of 1500 patients
Conclusion: The most common neurological disorders in the outpatient services are headache, neck pain, backache, fibromyalgia, stroke, epilepsy, and neuropathies. Newly joined residents should be well trained to efficiently manage these common outpatient disorders.
Source: Neurology India - July 22, 2019 Category: Neurology Authors: Raghunandan Nadig Uday S Namapally Gosala Raja K Sarma Thomas Mathew Source Type: research

Harnessing the Four Elements for Mental Health
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is pre...
Source: Frontiers in Psychiatry - April 23, 2019 Category: Psychiatry Source Type: research

A descriptive pilot study of mitochondrial mutations & clinical phenotype in fibromyalgia syndrome.
A descriptive pilot study of mitochondrial mutations & clinical phenotype in fibromyalgia syndrome. Indian J Med Res. 2019 Jan;149(1):47-50 Authors: Danda S, Thomas BM, Paramasivam G, Thomas R, Mathew J, Danda D Abstract Background & objectives: : Fibromyalgia syndrome (FMS) is one of the most common chronic pain conditions of unknown aetiology. Mitochondrial dysfunction has been reported in FMS with some studies reporting the presence of mitochondrial mutation namely A3243G, which also causes mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes. This pilot study was condu...
Source: Indian J Med Res - December 31, 2018 Category: Research Authors: Danda S, Thomas BM, Paramasivam G, Thomas R, Mathew J, Danda D Tags: Indian J Med Res Source Type: research

The Case For Sauna Bathing Is Stronger Than Ever
A new research review has plenty of good news for people who love a good sauna session: Studies overwhelmingly suggest that the relaxing habit is also a healthy one. A paper published Wednesday in Mayo Clinic Proceedings gathered existing findings on Finnish sauna bathing, the practice of spending time in relatively dry rooms heated to between 80 and 100 degrees, interspersed with periods of cooling. The results were culled from more than 70 studies published up through February 2018. Overall, the research suggests that “sauna bathing, an activity used for the purposes of pleasure, wellness, and relaxation, is linked...
Source: TIME: Health - August 1, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime Research Source Type: news

Chronic diseases and socioeconomic inequalities in quality of life among Brazilian adults: findings from a population-based study in Southern Brazil
ConclusionsThe occurrence of long-lasting chronic diseases is associated with inequalities in QoL (physical and psychological domains), with stronger adverse effects among older adults, blacks and individuals with lower income or educational levels.
Source: The European Journal of Public Health - December 25, 2017 Category: General Medicine Source Type: research

Characterization of pain and fatigue following deployment-related mild traumatic brain injury (P5.149)
Conclusions:This exploratory analysis suggests that severity of headache pain and degree of fatigue are interrelated following mTBI, and the most prominent dimensions of fatigue are general, mental and reduced activity, rather than reduced motivation.Study Supported by:National Institute of Neurological Disorders and Stroke Clinical Neuroscience ProgramDisclosure: Dr. Lewis has nothing to disclose. Dr. Knutson has nothing to disclose. Dr. Wassermann has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lewis, J., Knutson, K., Wassermann, E. Tags: Clinical Neuro-rehabilitation Source Type: research