The Role of Depressive Disorders in Autonomic Cardiovascular Dysregulation in Fibromyalgia

This study investigated the role of comorbid depression in autonomic cardiovascular dysregulations in fibromyalgia. Methods Cardiovascular recordings were obtained in 53 participants with fibromyalgia who also had depression (n = 27), in participants with fibromyalgia without depression (n = 26), and in 29 healthy controls, at rest and during a cold pressor test and an arithmetic task. Assessed parameters included interbeat interval, blood pressure, heart rate variability, baroreflex sensitivity, stroke volume, preejection period, left ventricular ejection time, Heather index, and total peripheral resistance. Results Participants with both fibromyalgia and depression displayed lower tonic interbeat interval, baroreflex sensitivity, and heart rate variability compared with participants with fibromyalgia without depression and controls (p values
Source: Psychosomatic Medicine - Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research