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Total 25 results found since Jan 2013.

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? Clinical Sciences
Conclusions— In children with dissection and transient cerebral arteriopathy, cerebral arteries demonstrate increased tortuosity. Quantified arterial tortuosity may represent a clinically relevant imaging biomarker of vascular biology in pediatric stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Wei, F., Diedrich, K. T., Fullerton, H. J., deVeber, G., Wintermark, M., Hodge, J., Kirton, A., the Vascular Effects of Infection in Pediatric Stroke (VIPS) Investigators, Dowling, Benedict, Bernard, Fox, Friedman, Lo, Ichord, Tan, Mackay, Hernandez, Hump Tags: Risk Factors, Angiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Clinical Sciences Source Type: research

White Matter Changes on Magnetic Resonance Imaging: A Risk Factor for Stroke in an African Population?
Background: White matter changes are frequently observed incidental findings in elderly individuals. Many studies in Europe and the United States have assessed the association of white matter changes with stroke and other diseases. No similar study has been conducted in sub-Saharan Africa, where risk factors for stroke differ. Our objective was to explore the association between severity of white matter changes (based on visual rating scales) and stroke in a Nigerian population.Methods: Magnetic resonance imaging (MRI) scans of 50 patients were retrospectively assessed and scored using 3 different visual rating scales (by ...
Source: Journal of Stroke and Cerebrovascular Diseases - February 4, 2013 Category: Neurology Authors: Godwin I. Ogbole, Mayowa O. Owolabi, Bolutife P. Yusuf Tags: Original Articles Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Structurofunctional resting-state networks correlate with motor function in chronic stroke
Conclusion The results demonstrate that changes after a stroke in both intrinsic and network-based structurofunctional correlations at rest are correlated with motor function, underscoring the importance of residual structural connectivity in cortical networks.
Source: NeuroImage: Clinical - July 29, 2017 Category: Radiology Source Type: research

The impact of constraint induced movement therapy on brain activation in chronic stroke patients with upper extremity paralysis: An fMRI study
This study is designed to explore the impact of constraint‐induced movement therapy (CIMT) on brain activation in chronic stroke patients with upper extremity paralysis and seek valuable predictors of recovery. Six chronic stroke patients with right hand dysfunction and nine healthy control subjects participated in the study. The patient's hand function was assessed by the Action Research Arm Test and statistical significance was determined by a paired Student's t‐tests. We conducted functional magnetic resonance imaging and analyzed the data using Analysis of Functional Neuroimages software. After CIMT, function of th...
Source: International Journal of Imaging Systems and Technology - August 13, 2014 Category: Radiology Authors: Bo Wen, Lin Ma, Changshui Weng Tags: Research Article Source Type: research

Quantitative assessment of hyperacute cerebral infarction with intravoxel incoherent motion MR imaging: Initial experience in a canine stroke model
ConclusionIVIM imaging could simultaneously evaluate the diffusion and microvascular perfusion characteristics in hyperacute strokes.Level of Evidence:2J. Magn. Reson. Imaging 2016
Source: Journal of Magnetic Resonance Imaging - November 29, 2016 Category: Radiology Authors: Qian ‐Qian Gao, Shan‐Shan Lu, Xiao‐Quan Xu, Cheng‐Jiang Wu, Xing‐Long Liu, Sheng Liu, Hai‐Bin Shi Tags: Original Research Source Type: research

Decreased CSF Levels of ß-Amyloid in Patients With Cortical Superficial Siderosis
Conclusions: Our results demonstrate that the presence and extent of cSS are associated with reduced CSF ß-amyloid 42 levels. Further studies are needed to investigate the underlying mechanisms of this association. Introduction Cerebral amyloid angiopathy (CAA)—characterized by the deposition of ß-amyloid in the walls of leptomeningeal vessels—is a common cerebral small vessel disease and a major cause of intracerebral hemorrhage in the elderly (1–3). Furthermore, it has become evident that CAA is associated with cognitive impairment (4). Specifically, it has been shown that ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization
Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence. Introduction Paraclinoid aneurysms are defined as aneurysms arising from the segment of the internal carotid artery (ICA) between the distal dural ring and the origin of the posterior communicating artery. They account for approximately 1.3–5% of all intracranial aneurysms and they comprise the majority of such aneurysms in females (1–3). Hemodynamic characteristics are thought to be the most important risk factors for occurrence...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Sex Differences in Sex Hormone Profiles and Prediction of Consciousness Recovery After Severe Traumatic Brain Injury
Conclusion: These findings indicate that TBI differentially affects the levels of sex-steroid hormones in men and women patients. Plasma levels of testosterone could be a good candidate blood marker to predict recovery from unconsciousness after sTBI for male patients. Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is increasing in incidence (1). Patients with acute severe TBI (sTBI) often develop severe disorders of consciousness, i.e., coma, minimally conscious state or vegetative state. Although many patients may regain consciousness during the 1-month post-TBI p...
Source: Frontiers in Endocrinology - April 25, 2019 Category: Endocrinology Source Type: research

MRI for all: Cheap portable scanners aim to revolutionize medical imaging
.news-article__hero--featured .parallax__element{ object-position: 47% 50%; -o-object-position: 47% 50%; } The patient, a man in his 70s with a shock of silver hair, lies in the neuro intensive care unit (neuro ICU) at Yale New Haven Hospital. Looking at him, you’d never know that a few days earlier a tumor was removed from his pituitary gland. The operation didn’t leave a mark because, as is standard, surgeons reached the tumor through his nose. He chats cheerfully with a pair of research associates who have come to check his progress with a new and potentially revolutionary device they are testing. The cylind...
Source: Science of Aging Knowledge Environment - February 23, 2023 Category: Geriatrics Source Type: research

Migraine, carotid stiffness and genetic polymorphism.
MIGRAINE, CAROTID STIFFNESS AND GENETIC POLYMORPHISM. Acta Clin Croat. 2015 Dec;54(4):409-16 Authors: Kes VB, Jurasić MJ, Zavoreo I, Corić L, Rotim K Abstract Recently migraine has been associated with increased arterial stiffness, procoagulant state, increased incidence of cerebral white matter lesions (WML) and stroke. Our aim was to compare the characteristics of migraineurs to headache free controls regarding their functional carotid ultrasound parameters. Sixty patients (45 women) with migraine (mean age 40.42 ± 10.61 years) were compared with 45 controls (30 women) with no prior history of rep...
Source: Acta Clinica Croatica - March 29, 2016 Category: Journals (General) Tags: Acta Clin Croat Source Type: research

Morphological and Whole-Word Semantic Processing Are Distinct: Event Related Potentials Evidence From Spoken Word Recognition in Chinese
In conclusion, the present study provides electrophysiological evidence of the dissociation of morphological and whole-word semantic processing in Chinese spoken word processing. The results identified a central-anterior morphological N400 effect when morphemic meaning conflicts with whole-word semantics, in addition to a classic semantic N400 effect with significantly reduced amplitude in central-parietal areas. Our results also showed that the morphological N400 effect is negatively correlated with reading ability. These results demonstrate the important role of morphological processing in Chinese spoken word recognition...
Source: Frontiers in Human Neuroscience - April 16, 2019 Category: Neuroscience Source Type: research

Efficient method for analyzing MR real‐time cines: Toward accurate quantification of left ventricular function
ConclusionCompared with the laborious frame‐by‐frame visual inspection, as conventionally adopted, the proposed method is efficient in analyzing real‐time cines for the accurate quantification of LV function without excessively manual interactions.J. Magn. Reson. Imaging 2015.
Source: Journal of Magnetic Resonance Imaging - March 1, 2015 Category: Radiology Authors: Yin Wu, Ke Jiang, Na Zhang, Yinzhu Gao, Yucheng Chen, Hairong Zheng, Xin Liu, Yiu‐Cho Chung Tags: Technical Development Source Type: research