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Total 908 results found since Jan 2013.

Capital idea: Trenton health system launches region's first mobile stroke unit
Capital Health is hitting the streets in Mercer County Monday with the region ’s first mobile stroke unit. “What we have is a stroke-ready hospital on wheels,” said Dr. Michael Stiefel, director of the Capital Institute for Neurosciences and the Stroke and Cerebrovascular Center at Capital Health in Trenton. “We can bring this to patients, rather than bring patients to the hospital, when time is critical.” The mobile unit was funded through a portion of a $2 million grant the health system…
Source: bizjournals.com Health Care:Biotechnology headlines - January 30, 2017 Category: Biotechnology Authors: John George Source Type: news

Safety and efficacy of thrombectomy in acute ischaemic stroke (REVASCAT): 1-year follow-up of a randomised open-label trial
We report the results of the prespecified 12-month analysis of the REVASCAT trial. Methods Patients with acute ischaemic stroke who could be treated within 8 h of symptom onset were randomly assigned to medical therapy (including intravenous alteplase when eligible) and neurovascular thrombectomy with Solitaire FR or medical therapy alone. The main secondary outcome measure at 1 year follow-up was disability, measured using the modified Rankin Scale (mRS), ranging from 0 (no symptoms) to 6 (death) with categories 5 (severe disability) and 6 (death) collapsed into one category (severe disability or death), analysed as the d...
Source: The Lancet Neurology - March 16, 2017 Category: Neurology Source Type: research

Early cognitive decline in symptomatic carotid stenosis is related to plaque inflammation and concomitant intracranial stenosis (P4.258)
Conclusions:Early cognitive decline is common among patients with symptomatic stenosis of the extracranial carotid artery, especially when associated with concomitant intracranial stenosis and plaque inflammation.Study Supported by: This study is supported by a grant from the National Medical Research Council, Singapore.Disclosure: Dr. Tan has nothing to disclose. Dr. Bharatendu has nothing to disclose. Dr. Paliwal has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tan, C. H., Bharatendu, C., Paliwal, P., Teoh, H. L., Chan, B., Dong, Y., Sinha, A., Sharma, V. K. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

The effect of baseline blood pressure on the benefit and safety of intra-arterial treatment in MR CLEAN. (S8.005)
Conclusions:Blood pressure does not affect the benefit or safety of IAT in patients with acute ischemic stroke caused by proximal intracranial vessel occlusion. Our data provide no arguments to withhold or delay IAT based on blood pressure.Study Supported by:The MR CLEAN trial was partly funded by the Dutch Heart Foundation and by unrestricted grants from AngioCare BV, Medtronic/Covidien/EV3®, MEDAC Gmbh/LAMEPRO, Penumbra Inc., Stryker®, and Top Medical/Concentric.Disclosure: Dr. Mulder has nothing to disclose. Dr. Ergezen has nothing to disclose. Dr. Lingsma has nothing to disclose. Dr. Berkhemer has nothing to di...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mulder, M., Ergezen, S., Lingsma, H., Berkhemer, O., Fransen, P., Beumer, D., Van den Berg, L., Lycklama a Nijeholt, G., Emmer, B., Van der Worp, B., Nederkoorn, P., Roos, Y., Van Oostenbrugge, R., Van Zwam, W., Majoie, C., Van der Lugt, A., Dippel, D. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Treatment Source Type: research

UAB joins national stroke prevention initiative, partners with regional medical centers
UAB will take a leading role in joining the National Institutes of Health's StrokeNet with a grant of $1 million over five years from the Nationals Institute of Neurological Disorders and Stroke. NIH StrokeNet is a network of 25 regional centers across the U.S., involving over 200 hospitals, designated to serve as the infrastructure and pipeline for new potential treatments for patients with stroke as well as those at risk for stroke.  “If you look at a map of the location of StrokeNet centers,…
Source: bizjournals.com Health Care:Physician Practices headlines - August 28, 2018 Category: American Health Authors: Tyler Patchen Source Type: news

Botuloscope: 1-year follow-up of upper-limb post-stroke spasticity treated with botulinum toxin
Conclusion. This is the first long-term follow-up of BoNT-A treatment for upper-limb spasticity involving a large cohort independent of industry. Quality of life was improved by treating upper-limb spasticity with BoNT-A, even at 5 years post-stroke. Personalizing objectives of the treatment amplified its efficacy. BoNT-A was a powerful analgesic when pain was spasticity-related. Treating the spastic upper limb also improved balance and gait abilities.
Source: Annals of Physical and Rehabilitation Medicine - June 22, 2019 Category: Rehabilitation Source Type: research

Botuloscope: 1-year follow-up of upper limb post-stroke spasticity treated with botulinum toxin
ConclusionThis is the first long-term follow-up of BoNT-A treatment for upper limb spasticity involving a large cohort independent of industry. Quality of life was improved by treating upper limb spasticity with BoNT-A, even at 5 years post-stroke. Personalizing objectives of the treatment amplified its efficacy. BoNT-A was a powerful analgesic when pain was spasticity-related. Treating the spastic upper limb also improved balance and gait abilities.
Source: Annals of Physical and Rehabilitation Medicine - June 25, 2019 Category: Rehabilitation Source Type: research

Stem cell therapy promotes recovery from stroke and dementia in mice
A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia,a new UCLA study finds.Dementia can arise from multiple conditions, and it is characterized by an array of symptoms including problems with memory, attention, communication and physical coordination. The two most common causes of dementia are Alzheimer ’s disease and white matter strokes — small strokes that accumulate in the connecting areas of the brain.“It’s a vicious cycle: The two leading causes of dementia are almost always seen togeth...
Source: UCLA Newsroom: Health Sciences - April 22, 2021 Category: Universities & Medical Training Source Type: news

Multinuclear MRI Reveals Early Efficacy of Stem Cell Therapy in Stroke
Transl Stroke Res. 2022 Jul 28. doi: 10.1007/s12975-022-01057-w. Online ahead of print.ABSTRACTCompromised adult human mesenchymal stem cells (hMSC) can impair cell therapy efficacy and further reverse ischemic recovery. However, in vitro assays require extended passage to characterize cells, limiting rapid assessment for therapeutic potency. Multinuclear magnetic resonance imaging and spectroscopy (MRI/S) provides near real-time feedback on disease progression and tissue recovery. Applied to ischemic stroke, 23Na MRI evaluates treatment efficacy within 24 h after middle cerebral artery occlusion, showing recovery of sodiu...
Source: Cell Research - July 28, 2022 Category: Cytology Authors: Shannon Helsper Xuegang Yuan F Andrew Bagdasarian Jacob Athey Yan Li Cesario V Borlongan Samuel C Grant Source Type: research

Corrigendum to ‘Predictive value of the combination between the intracranial arterial culprit plaque characteristics and the Essen Stroke Risk Score for short-term stroke recurrence’ Journal of Stroke and Cerebrovascular Diseases Volume 31, Issue 9, September 2022, 106624
This study was funded by grants from the Nantong Municipal Science and Technology Plan Project (Nos. MS12020041, MS12021101, HS2019002) and Nantong Municipal Health Commission Youth Project (No. MB2020001).
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2022 Category: Neurology Authors: Kaixuan Ren, Huayun Jiang, Tiantian Li, Chengqun Qian, Shenchu Gong, Tianle Wang, Li Zhu Tags: Corrigendum Source Type: research

Predictors of Good Clinical Outcome in Acute Stroke Patients Underwent Recanalization Therapy (P01.242)
CONCLUSIONS: NIHSS at admission, recanalization grade and early neurological improvement are independent predictors of clinical outcome in AIS patients underwent mechanical recanalization.Supported by: IGA MH CR grants NT/11386-5/2010, NT/11046-6/2010, NT/13498-4/2012.Disclosure: Dr. Skoloudik has nothing to disclose. Dr. Roubec has nothing to disclose. Dr. Kuliha has nothing to disclose. Dr. Herzig has received personal compensation for activities with Bayer, Boehringer Ingelheim Pharmaceuticals, Inc., and Gedeon Richter. Dr. Sanak has received personal compensation from Boehringer Ingelheim for serving on a scientific ad...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Skoloudik, D., Roubec, M., Kuliha, M., Herzig, R., Sanak, D., Prochazka, V., Hrbac, T. Tags: P01 Cerebrovascular Disease I Source Type: research

UCLA researchers awarded $11 million grant to develop stroke prevention interventions for minorites
(University of California - Los Angeles Health Sciences) UCLA researchers and their partners across Los Angeles County have been awarded an $11 million grant to fund research on community-based interventions to reduce the higher rates of stroke and death from stroke among disadvantaged populations.
Source: EurekAlert! - Medicine and Health - May 1, 2013 Category: Global & Universal Source Type: news

NIH awards $40 million in grants to reduce stroke disparities in the U.S.
Four research centers will develop high-impact culturally tailored interventions aimed at lowering stroke risk among racial and ethnic minorities in the United States. Together the centers are expected to receive $40 million in funding over five years, contingent on the availability of funds from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
Source: National Institutes of Health (NIH) News Releases - May 1, 2013 Category: American Health Source Type: news

High blood pressure among blacks and young adults is focus of $11 million stroke prevention project
(University of California - San Francisco) A new $11 million grant to Kaiser Permanente Northern California and UC San Francisco will support a multifaceted research program aimed at lowering stroke risk among black populations and younger stroke victims by targeting high blood pressure, also known as hypertension.
Source: EurekAlert! - Social and Behavioral Science - June 19, 2013 Category: Global & Universal Source Type: news