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Thrombectomy emerges as option for rare stroke patients
Mechanical thrombectomy may be a safe approach for patients who have had a rar...Read more on AuntMinnie.comRelated Reading: PET/CT score may help predict major cardiac events EVT, neuroimaging lead to higher stroke care costs How does work compare between academic, private interventionalists? CT shows efficacy of recanalization in stroke patients AI spots large vessel occlusions, predicts patient outcome
Source: AuntMinnie.com Headlines - February 14, 2023 Category: Radiology Source Type: news

CYP2C9 Polymorphisms and the Risk of Cardiovascular Events in Patients Treated with Clopidogrel: Combined Data from the POPular Genetics and POPular AGE Trials
ConclusionsCarriers of aCYP2C9 *2 or *3 LoF allele presenting with acute coronary syndrome and treated with clopidogrel did not have an increased risk for thrombotic events compared with noncarriers. Given the limited number of poor metabolizers, no firm conclusions could be drawn with regard to the thrombotic risk for patients carrying two CYP2C9 LoF alleles.
Source: American Journal of Cardiovascular Drugs - February 14, 2023 Category: Cardiology Source Type: research

Perceived acceptable uncertainty regarding comparability of endovascular treatment alone versus intravenous thrombolysis plus endovascular treatment
Conclusion Physicians would generally feel comfortable skipping IVT before EVT at different certainty thresholds. Most physicians would treat with EVT alone if randomized trial data suggested that the number of patients achieving functional independence at 90 days was similar between the two groups, and one could be sufficiently sure that no more than 3 out of 100 patients would not achieve functional independence at 90 days due to skipping IVT.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Kaesmacher, J., Mujanovic, A., Treurniet, K., Kappelhof, M., Meinel, T. R., Yang, P., Liu, J., Zhang, Y., Zi, W., Yang, Q., Nogueira, R. G., Kimura, K., Matsumaru, Y., Suzuki, K., Yan, B., Mitchell, P. J., Miao, Z., Roos, Y. B. W. E. M., Majoie, C. B. L. Tags: Open access, Ischemic stroke Source Type: research

A qualitative evidence synthesis exploring people after stroke, family members, carers and healthcare professionals ’ experiences of early supported discharge (ESD) after stroke
ConclusionThe findings of this qualitative evidence synthesis highlight that experiences of ESD were largely very positive. The transition from ESD to community services was deemed to be problematic and other unmet needs such as information needs, and carer support require further investigation.
Source: PLoS One - February 13, 2023 Category: Biomedical Science Authors: Elaine O. Connor Source Type: research

Organization and costs of stroke care in outpatient settings: Systematic review
CONCLUSIONS: Thirty studies, of which 14 (46.6%) were related to post-stroke costs and 12 (40%) to cardiovascular prevention costs. The results show that most of them are retrospective analyzes of different databases of short-term hospital care, and do not allow a detailed analysis of the costs by different segments of services. The possibilities for improvement are centered on primary and secondary prevention, selection and pre-hospital transfer, early discharge with support, and social and health care.PMID:36773416 | DOI:10.1016/j.aprim.2023.102578
Source: Atencion Primaria - February 11, 2023 Category: Primary Care Authors: Jorgina Lucas-Noll Mar Lleix à-Fortuño Llu ïsa Queralt-Tomas Anna Panisello-Tafalla Miseric òrdia Carles-Lavila Jos é L Clua-Espuny Source Type: research

Inactivated whole-virion SARS-CoV-2 vaccines and long-term clinical outcomes in patients with coronary atherosclerosis disease in China: a prospective cohort study
CONCLUSIONS: Our results indicated no evidence of an increased ischemic or bleeding risk after vaccination with inactivated SARS-CoV-2 vaccine among Chinese patients with CAD, with limited statistical power.PMID:36756815 | DOI:10.1093/cvr/cvad031
Source: Atherosclerosis - February 9, 2023 Category: Cardiology Authors: Huajie Xu Jiaojiao Zheng Xin Zhao Qi Zhou Bing Fan Hongyi Wu Si Zhang Junbo Ge Source Type: research

Effects of Patient Comorbidities and Demographics on Episode-of-Care Costs Following Total Shoulder Arthroplasty
CONCLUSION: Providers should be aware that certain demographic variables and comorbidities (history of stroke, dementia, chronic pulmonary disease, anemia, heart disease, advanced age, and elevated body mass index) are associated with an increase in total costs following primary shoulder arthroplasty. Further study is required to determine whether bundled payment target costs should be adjusted to better compensate for specific comorbidities.LEVEL OF EVIDENCE: Level IV case series.PMID:36749879 | DOI:10.5435/JAAOS-D-22-00450
Source: The Journal of the American Academy of Orthopaedic Surgeons - February 7, 2023 Category: Orthopaedics Authors: Dominic M Farronato Joshua D Pezzulo Alexander J Rondon Sean Porrini Diane McGonigal Charles L Getz Daniel E Davis Source Type: research

Multicentre International Registry of Open Surgical Versus Percutaneous Upper Extremity Access During Endovascular Aortic Procedures
CONCLUSIONS: AF and stroke rates during complex aortic procedures employing UEA are non-negligible. Therefore, selective use of UEA is warranted. Percutaneous access with vessel closure devices is associated with similar complication rates, but more adjunctive endovascular procedures are required to avoid surgical exposure.PMID:36740094 | DOI:10.1016/j.ejvs.2023.01.046
Source: PubMed: Eur J Vasc Endovasc ... - February 5, 2023 Category: Surgery Authors: Luca Bertoglio Gustavo Oderich Andrea Melloni Mauro Gargiulo Tilo K ölbel Donald J Adam Luca Di Marzo Gabriele Piffaretti Christopher J Agrusa Wouter Van den Eynde SUPER-AXA Registry Collaborators Source Type: research

Single antiplatelet therapy directly after percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome patients: the OPTICA study
CONCLUSIONS: This study provides first-in-human evidence that P2Y12 inhibitor monotherapy directly following PCI for NSTE-ACS is feasible, without any overt safety concerns, and highlights the need for randomised controlled trials comparing direct P2Y12 inhibitor monotherapy with the current standard of care.PMID:36734020 | DOI:10.4244/EIJ-D-22-00886
Source: EuroIntervention - February 3, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Niels M R van der Sangen Bimmer E P M Claessen I Tarik K üçük Alexander W den Hartog Jan Baan Marcel A M Beijk Ronak Delewi Tim P van de Hoef Paul Knaapen Jorrit S Lemkes Koen M Marques Alexander Nap Niels J W Verouden M Marije Vis Robbert J de Winter Source Type: research