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Total 93 results found since Jan 2013.

Optimizing Prediction Scores for Poor Outcome After Intra-Arterial Therapy in Anterior Circulation Acute Ischemic Stroke Clinical Sciences
Conclusions— The HIAT2 score, which combines clinical and imaging variables, performed better than all previous scores in predicting poor outcome after IAT for anterior circulation large artery occlusions.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Sarraj, A., Albright, K., Barreto, A. D., Boehme, A. K., Sitton, C. W., Choi, J., Lutzker, S. L., Sun, C.-H. J., Bibars, W., Nguyen, C. B., Mir, O., Vahidy, F., Wu, T.-C., Lopez, G. A., Gonzales, N. R., Edgell, R., Martin-Schild, S., Hallevi, H., Chen, P. Tags: Acute Cerebral Infarction, Angioplasty and Stenting Clinical Sciences Source Type: research

Effectiveness of clot-buster enhanced by ultrasound device in stroke patients
A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients. The results of the phase II pilot study were reported in the American Heart Association journal Stroke. Lead author is Andrew D. Barreto, M.D., assistant professor of neurology in the Stroke Program at the UTHealth Medical School. Principal investigator is James C. Grotta, M.D., professor and chair of the Department of Neurology at the UTHealth Medical School, the Roy M...
Source: Health News from Medical News Today - October 27, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

A Smartphone Application To Aid In The Evaluation, Treatment, And Clinical Trial Enrollment Of The Acute Stroke Patient (P7.125)
CONCLUSION: A smartphone application that centralizes various disparate resources may allow for more efficient management of the acute stroke patient. Further, such an application may allow easy screening for clinical trials by new practitioners as they learn of the various inclusion criteria for their studies.Disclosure: Dr. Nguyen has received royalty, or license fee, or contractual rights payments from the University of Texas. Dr. Wu has nothing to disclose. Dr. Barreto has nothing to disclose. Dr. Grotta has received personal compensation for activities with Lundbeck as a consultant. Dr. Savitz has received personal co...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Nguyen, C., Wu, T.-C., Barreto, A., Grotta, J., Savitz, S. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

New treatment for stroke recovery shows early success
Researchers at The University of Texas at Dallas have taken a step toward developing a new treatment to aid the recovery of limb function after strokes. In a study published online in the journal Neurobiology of Disease, researchers report the full recovery of forelimb strength in animals receiving vagus nerve stimulation. "Stroke is a leading cause of disability worldwide," said Dr. Navid Khodaparast, a postdoctoral researcher in the School of Behavioral and Brain Sciences and lead author of the study. "Every 40 seconds, someone in the U.S. has a stroke...
Source: Health News from Medical News Today - October 3, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Clotting Factors to Treat Thrombolysis-related Symptomatic Intracranial Hemorrhage in Acute Ischemic Stroke
Conclusions: We found no evidence that treatment for sICH with clotting factors has a favorable effect on clinical or radiological outcomes. However, the sample was small because of the low frequency of sICH. New treatments are urgently needed for this uncommon yet serious condition.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2013 Category: Neurology Authors: Yazan J. Alderazi, Niravkumar V. Barot, Hui Peng, Farhaan S. Vahidy, Digvijaya D. Navalkele, Navdeep Sangha, Vivek Misra, Sean I. Savitz Tags: Original Articles Source Type: research

World-Wide Efficacy of Bone Marrow Derived Mesenchymal Stromal Cells in Preclinical Ischemic Stroke Models: Systematic Review and Meta-Analysis
Conclusions: Our results show worldwide efficacy of BM-MSCs in improving functional outcomes in pre-clinical animal models of stroke and support testing these cells in clinical trials in various ranges of time windows using different delivery routes. The continued growing number of publications showing functional benefit of BM-MSCs are now adding limited value to an oversaturated literature spanning 18 years. Researchers should focus on identifying definitive mechanisms on how BM-MSCs lead to benefit in stroke models. Introduction Ischemic stroke is the 5th leading cause of death and the leading cause of long term di...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Hospital-Acquired Symptomatic Urinary Tract Infection in Patients Admitted to an Academic Stroke Center Affects Discharge Disposition
Objective: To test the role of hospital-acquired symptomatic urinary tract infection (SUTI) as an independent predictor of discharge disposition in the acute stroke patient. Study Design: A retrospective study of data collected from a stroke registry service. The registry is maintained by the Specialized Programs of Translational Research in Acute Stroke Data Core. The Specialized Programs of Translational Research in Acute Stroke is a national network of 8 centers that perform early phase clinical projects, share data, and promote new approaches to therapy for acute stroke. Setting: A single university-based hospital...
Source: PM and R - October 29, 2012 Category: Rehabilitation Authors: Nneka L. Ifejika-Jones, Hui Peng, Elizabeth A. Noser, Gerard E. Francisco, James C. Grotta Tags: Original Research Source Type: research

Device used to close small hole in heart may protect against recurrent stroke
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial led by UCLA researchers.“It is a major new treatment option for some people,” said Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center and lead author of the study. However, he added, “Using the device is going to have to be a considered clinical decision between the doctor and the patient about who’s the right person to get it.”Thefindings appear in the Sept. 14 New England Jo...
Source: UCLA Newsroom: Health Sciences - September 14, 2017 Category: Universities & Medical Training Source Type: news

Radiation Monitoring Results from the First Year of Operation of a Unique Ambulance-based Computed Tomography Unit for the Improved Diagnosis and Treatment of Stroke Patients.
Abstract When a blood clot blocks the blood supply to the brain or when a blood vessel bursts, resulting in brain cell death, the medical condition is referred to as a "stroke." Stroke is a main cause of death worldwide and is a common cause of disability. A common form of stroke, called ischemic stroke, is when blood flow to the brain is decreased. Clinical research has revealed that treatment within the very first hours of symptom onset is key for ischemic stroke with recanalization of occluded arteries by thrombolysis with alteplase. Computed tomography (CT) is one of the diagnostic tools used to determine if t...
Source: Health Physics - March 31, 2016 Category: Physics Authors: Gutiérrez JM, Emery RJ, Parker SA, Jackson K, Grotta JC Tags: Health Phys Source Type: research

Differences in the last known well time between neurology, ED providers and EMS providers. (P1.273)
Conclusions:Our study suggests there is no good agreement between the ED and neurology LKW times. The addition of a short standardized questionnaire may help further improve LKW times.Disclosure: Dr. Doyle has nothing to disclose. Dr. Horton has nothing to disclose. Dr. Magadan has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Doyle, A., Horton, L., Magadan, A. Tags: Pre-Hospital Stroke, Tele-Stroke, and mHealth Source Type: research

The University of Texas Houston Stroke Registry (UTHSR): implementation of enhanced data quality assurance procedures improves data quality
Conclusions: Establishment of a rigorous data quality assurance for our UTHSR has helped to improve the validity of data. We observed an excellent IRR between the two abstractors. We recommend training of chart abstractors and systematic assessment of IRR between abstractors and validity of the abstracted data in stroke registries.
Source: BioMed Central - June 15, 2013 Category: Journals (General) Authors: Mohammad H RahbarNicole R GonzalesManouchehr Ardjomand-HessabiAmirali TahananMelvin R SlineHui PengRenganayaki PandurenganFarhaan S VahidyJessica D TanksleyAyodeji A DelanoRene M MalazarteEllie E ChoiSean I SavitzJames C Grotta Source Type: research

Ischemic stroke in patients with gliomas at The University of Texas-M.D. Anderson Cancer Center
Abstract Patients with gliomas are at risk of cerebrovascular accidents (CVA) with potential consequences on survival, function, and local tumor control. Our objective was to provide information about CVA in patients with gliomas and to estimate survival in this group. We reviewed all adult glioma patients with ischemic CVA at the University of Texas-M.D. Anderson Cancer Center from 2003 through 2014. We extracted demographic, clinical, imaging, treatment and outcome data. We used descriptive summary data and estimated or compared survival rates where appropriate. 60 of 6500 patients (0.1 %) with high-grade (HGG,...
Source: Journal of Neuro-Oncology - August 14, 2015 Category: Cancer & Oncology Source Type: research

Stroke prevention drug combo shows promise, study says
(University of Texas at Austin) If you've had a minor stroke or a transient ischemic stroke (TIA), taking the clot-preventing drug clopidogrel along with aspirin may lower your risk of having a major stroke within the next 90 days, according to new research published in The New England Journal of Medicine.
Source: EurekAlert! - Medicine and Health - May 16, 2018 Category: International Medicine & Public Health Source Type: news

UT Dallas researchers find early success in new treatment for stroke recovery
(University of Texas at Dallas) Researchers at The University of Texas at Dallas conducted a study testing vagus nerve stimulation as a possible technique to improve recovery from stroke. The stimulation method already is approved for use in humans for treating a number of diseases. In the animal study, researchers found that pairing vagus nerve stimulation with physical rehabilitation returned all of the rats in the trial group to pre-stroke levels -- double the effectiveness of rehabilitation alone.
Source: EurekAlert! - Social and Behavioral Science - October 1, 2013 Category: Global & Universal Source Type: news

Optimism after a stroke could ward off life-changing disability by slashing brain inflammation
In a study of 49 stroke survivors researchers at The University of Texas examined the relationship between optimism and recovery for three months after a stroke.
Source: the Mail online | Health - February 12, 2020 Category: Consumer Health News Source Type: news