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Total 276 results found since Jan 2013.

Voluntary exercise ameliorates the good limb training effect in a mouse model of stroke.
This study used a mouse model to investigate if post-stroke exercise could prevent deterioration of the function of the impaired limb despite compensatory training of the intact limb. Results showed that mice that exercised, in combination with intact limb training, demonstrated improved functional outcome compared to mice that received no training or compensatory limb training only. These findings suggest that exercise can prevent the deterioration of impaired limb functional outcome that is typically seen with intact limb use. PMID: 33388904 [PubMed - as supplied by publisher]
Source: Experimental Brain Research - January 3, 2021 Category: Neuroscience Authors: Nemchek V, Haan EM, Mavros R, Macuiba A, Kerr AL Tags: Exp Brain Res Source Type: research

Sensors, Vol. 21, Pages 1806: Development of a Low-Cost, Modular Muscle –Computer Interface for At-Home Telerehabilitation for Chronic Stroke
We describe our modular electromyography acquisition, processing, and feedback algorithms to train differentiated muscle control during at-home therapist-guided sessions. Additionally, we evaluated the performance of low-cost sensors for our training task with two healthy individuals. Finally, we present the results of a case study with a stroke survivor who used the system for 40 sessions over 10 weeks of training. In line with our previous research, our results suggest that using low-cost sensors provides similar results to those using research-grade sensors for low forces during an isometric task. Our preliminary case s...
Source: Sensors - March 5, 2021 Category: Biotechnology Authors: Octavio Marin-Pardo Coralie Phanord Miranda Rennie Donnelly Christopher M. Laine Sook-Lei Liew Tags: Article Source Type: research

Mayo Clinic Minute: African Americans at higher risk of stroke
May is National Stroke Awareness Month. According to the CDC, a stroke occurs every 40 seconds in the U.S. Do you know that stroke is a leading cause of death and disability in the United States? A stroke happens when blood supply to the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This causes brain cells to become damaged or die. Risks of stroke vary by race and ethnicity. African American…
Source: News from Mayo Clinic - May 6, 2022 Category: Databases & Libraries Source Type: news

EMAGINE –Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke
Stroke is a leading cause of disability with limited effective interventions that improve recovery in the subacute phase. This protocol aims to evaluate the safety and efficacy of a non-invasive, extremely low-frequency, low-intensity, frequency-tuned electromagnetic field treatment [Electromagnetic Network Targeting Field (ENTF) therapy] in reducing disability and promoting recovery in people with subacute ischemic stroke (IS) with moderate-severe disability and upper extremity (UE) motor impairment. Following a sample-size adaptive design with a single interim analysis, at least 150 and up to 344 participants will be rec...
Source: Frontiers in Neurology - May 5, 2023 Category: Neurology Source Type: research

Prehospital Stroke Assessment for Large Vessel Occlusions: A Systematic Review.
CONCLUSION: At this time, further evaluations must be done in the prehospital setting to determine the ease of use and true sensitivity and specificity of these scales in identifying LVOs. PMID: 29023166 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - October 14, 2017 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Transcatheter closure of patent foramen ovale for secondary prevention of ischemic stroke: Quantitative synthesis of pooled randomized trial data
ConclusionsBased on the results of this analysis of randomized trial data, percutaneous PFO closure appears to be a safe and effective therapeutic option for the secondary prevention of ischemic stroke in patients with PFO and cryptogenic stroke.
Source: Catheterization and Cardiovascular Interventions - January 14, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Abdul Hakeem, Mehmet Cilingiroglu, Angelos Katramados, Konstantinos Dean Boudoulas, Cezar Iliescu, Betul Gundogdu, Konstantinos Marmagkiolis Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

A new era in stroke care gives larger treatment window and better outcomes
According to the American Heart/American Stroke Association, stroke affects nearly 800,000 people in the United States each year. It is the fifth leading cause of death, and the leading cause of long-term disability.  It’s also the leading cause of preventable disability. In China it is the leading cause of death surpassing both cancer and heart disease. Stroke occurs when a blood vessel carrying oxygen and nutrients to the brain is either blocked by a blood clot or plaque (ischemic stroke), or…
Source: bizjournals.com Health Care News Headlines - August 15, 2018 Category: Health Management Authors: Alexandria Foley Source Type: news

Anesthetic Management of Emergency Endovascular Thrombectomy for Acute Ischemic Stroke, Part 1: Patient Characteristics, Determinants of Effectiveness, and Effect of Blood Pressure on Outcome.
Abstract In the United States, stroke ranks fifth among all causes of death and is the leading cause of serious long-term disability. The 2018 American Heart Association stroke care guidelines consider endovascular thrombectomy to be the standard of care for patients who have acute ischemic stroke in the anterior circulation when arterial puncture can be made within 6 hours of symptom onset or within 6-24 hours of symptom onset when specific eligibility criteria are satisfied. The aim of this 2-part review is to provide practical perspective on the clinical literature regarding anesthesia care of patients treated ...
Source: Anesthesia and Analgesia - March 20, 2019 Category: Anesthesiology Authors: Hindman BJ Tags: Anesth Analg Source Type: research

Leveraging Health Information Exchange to Construct a Registry for Traumatic Brain Injury, Spinal Cord Injury and Stroke in Indiana.
Authors: Rahurkar S, McFarlane TD, Wang J, Hoover S, Hammond F, Kean J, Dixon BE Abstract Traumatic brain injury (TBI), spinal cord injury (SCI) and stroke are conditions of interest to public health as they can result in long-term outcomes and disabilities. Specialized registries can facilitate public health surveillance, however only 4% of hospitals in the United States actively engage in electronic reporting to these registries. We leveraged electronic claims and clinical data from a health information exchange to create a statewide TBI/SCI/Stroke registry to facilitate the study of long-term outcomes and health...
Source: AMIA Annual Symposium Proceedings - April 16, 2019 Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research

Dimensions of post-stroke depression and neuropsychological deficits in older adults
Stroke is the leading cause of both serious and long-term disability and the fifth leading cause of death in the United States.1,2 Post-stroke depression (PSD) afflicts approximately one-fourth of stroke survivors and increases the likelihood of persistent disability.3-6 Prompt identification and treatment of PSD can improve affective symptoms and stroke related disability.7,8
Source: The American Journal of Geriatric Psychiatry - January 24, 2020 Category: Geriatrics Authors: Dora Kanellopoulos, Victoria Wilkins, Jimmy Avari, Lauren Oberlin, Lindsay Arader, Merete Chaplin, Samprit Banerjee, George S. Alexopoulos Tags: Regular Research Article Source Type: research

Monoclonal antibody as an emerging therapy for acute ischemic stroke.
Authors: Woods D, Jiang Q, Chu XP Abstract Acute ischemic stroke (AIS) is the 5th leading cause of death and the leading cause of neurological disability in the United States. The oxygen and glucose deprivation associated with AIS not only leads to neuronal cell death, but also increases the inflammatory response, therefore decreasing the functional outcome of the brain. The only pharmacological intervention approved by the US Federal Food and Drug Administration for treatment of AIS is tissue plasminogen activator (t-PA), however, such treatment can only be given within 4.5 hours of the onset of stroke-like sympto...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - September 18, 2020 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research

Artificial Intelligence and Stroke Imaging
This article addresses this topic and seeks to present an overview of machine learning and/or deep learning applied to stroke imaging.
Source: Neuroimaging Clinics - September 17, 2020 Category: Radiology Authors: Guangming Zhu, Bin Jiang, Hui Chen, Elizabeth Tong, Yuan Xie, Tobias D. Faizy, Jeremy J. Heit, Greg Zaharchuk, Max Wintermark Source Type: research

The Caregiver Experience After Stroke in a COVID-19 Environment: A Qualitative Study in Inpatient Rehabilitation.
CONCLUSIONS: Caregiver attendance at therapy sessions and frequent, direct communication between staff and caregivers improved caregiver readiness for family member discharge following inpatient rehabilitation. This study shared perspectives from a distinctive time during the COVID-19 pandemic. If visitation for multiple therapy sessions is prohibited, we recommend taking alternative measures to keep the caregiver involved in the plan of care.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A326). PMID: 33086240 [PubMed ...
Source: Physical Therapy - October 20, 2020 Category: Physiotherapy Authors: Sutter-Leve R, Passint E, Ness D, Rindflesch A Tags: J Neurol Phys Ther Source Type: research

Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation
Ischemic stroke is the most widespread cause of disability and a leading cause of death in developed countries. To date, the most potent approved treatment for acute stroke is recanalization therapy with thrombolytic drugs such as tissue plasminogen activator (rt-PA or tPA) or endovascular mechanical thrombectomy. Although tPA and thrombectomy are widely available in the United States, it is currently estimated that only 10–20% of stroke patients get tPA treatment, in part due to restrictive selection criteria. Recently, however, tPA and thrombectomy selection criteria have loosened, potentially allowing more patients to...
Source: Frontiers in Neurology - March 15, 2021 Category: Neurology Source Type: research