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Total 133 results found since Jan 2013.

Tick-borne Encephalitis: Stroke-like Presentation
We report a unique case of clinical symptoms and radiological findings compatible with a stroke-like inflammatory lesion in the thalamus, suggesting microangiopathy from TBEV. Our case shows that TBEV could be a possible cause of stroke-like lesions.
Source: Journal of Stroke and Cerebrovascular Diseases - June 9, 2019 Category: Neurology Authors: Andreas Eleftheriou, Fredrik Lundin, Evangelos Alexandros Petropoulos Tags: Case Report Source Type: research

Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Fraction of stroke mortality attributable to alcohol consumption in Russia.
Abstract Stroke is an international health problem with high associated human and economic costs. The mortality rate from stroke in Russia is one of the highest in the world. Risk factors identification is therefore a high priority from the public health perspective. Epidemiological evidence suggests that binge drinking is an important determinant of high stroke mortality rate in Russia. The aim of the present study was to estimate the premature stroke mortality attributable to alcohol abuse in Russia on the basis of aggregate-level data of stroke mortality and alcohol consumption. Age-standardized sex-specific ma...
Source: Adicciones - September 19, 2014 Category: Addiction Authors: Y E R Tags: Adicciones Source Type: research

Podcast: Cerebrolysin for acute ischaemic stroke
When someone has an acute ischemic stroke, urgent and reliable treatments will reduce their risks of disability or dying from their brain tissue damage. The treatments used vary around the world, and a drug called cerebrolysin is widely used in post-Soviet countries, Eastern Europe, Central and Southeast Asia. In April 2017, the latest update of this review was published by researchers from Kazan Federal University in Russia and Chinara Razzakova, a PhD student from the university interviewed one of the authors, Liliya Eugenevna, for this podcast." This Cochrane Review is about a medicine called cerebrolysin, which is used...
Source: Cochrane News and Events - January 10, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Multilocus analysis of the association of polymorphic variants of inflammation genes with ischemic stroke in Russians.
Abstract Carriage frequencies of alleles and genotypes of polymorphic loci of inflammation genes (49A>G CTLA4, 41G>A and 87C>T PDE4D, -590C>T IL4, -308A>G TNF, 252G>A LTA, 874A>T IFNG, -509С>Т, 869T>C and 915G>C TGFB1) were determined in a sample of 200 patients diagnosed with ischemic stroke and in the control group similar in gender and age (146 individuals), all ethnic Russians. The positive association of the allele PDE4D*87C (р = 0.028) and genotype TGFB1*-509Т/Т (р = 0.02) carriage with ischemic stroke was shown. The association of the disease with the carriage of the alle...
Source: Molekuliarnaia Biologiia - June 30, 2016 Category: Molecular Biology Authors: Titov BV, Matveeva NA, Martynov MY, Favorova OO Tags: Mol Biol (Mosk) Source Type: research

Cerebrolysin for acute ischaemic stroke.
CONCLUSIONS: Moderate-quality evidence indicates that Cerebrolysin probably has little or no beneficial effect on preventing all-cause death in acute ischaemic stroke, or on the total number of people with serious adverse events. Moderate-quality evidence also indicates a potential increase in non-fatal serious adverse events with Cerebrolysin use. PMID: 32662068 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - July 13, 2020 Category: General Medicine Authors: Ziganshina LE, Abakumova T, Hoyle CH Tags: Cochrane Database Syst Rev Source Type: research

Trends in deaths and disability-adjusted life-years of stroke attributable to high body-mass index worldwide, 1990 –2019
ConclusionA range of indicators for the global burden of stroke attributable to HBMI have been on the rise for the past three decades. Tremendous efforts worldwide should be in place to control and treat stroke attributable to HBMI, especially in regions with high-middle and middle SDIs and among middle-aged and aged populations.
Source: Frontiers in Neurology - June 30, 2023 Category: Neurology Source Type: research

The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors.
Conclusions: Rus-OCS is a promising cognitive screening instrument for Russian-speaking patients. However, further validation is needed. Constraints of socioeconomic differences between Russian speakers in the wider population should be considered. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
Source: Neuropsychology - October 15, 2018 Category: Neurology Source Type: research

OnabotulinumtoxinA for the Treatment of Post-Stroke Distal Lower-Limb Spasticity: A Randomized Trial
Conclusions OnabotulinumtoxinA significantly improved ankle MAS, CGI, and GAS scores compared with placebo; improvements were consistent and increased with repeated treatments of onabotulinumtoxinA over 1 year in patients with PSLLS. Clinical Trial Registration URL: https://clinicaltrials.gov/ct2/show/NCT01575054?term=NCT01575054&rank=1
Source: PMandR - January 10, 2018 Category: Rehabilitation Source Type: research

Genes, Vol. 14, Pages 1171: Association between HSPA8 Gene Variants and Ischemic Stroke: A Pilot Study Providing Additional Evidence for the Role of Heat Shock Proteins in Disease Pathogenesis
Olga Y. Bushueva HSPA8 is involved in many stroke-associated cellular processes, playing a pivotal role in the protein quality control system. Here we report the results of the pilot study aimed at determining whether HSPA8 SNPs are linked to the risk of ischemic stroke (IS). DNA samples from 2139 Russians (888 IS patients and 1251 healthy controls) were genotyped for tagSNPs (rs1461496, rs10892958, and rs1136141) in the HSPA8 gene using probe-based PCR. SNP rs10892958 of HSPA8 was associated with an increased risk (risk allele G) of IS in smokers (OR = 1.37; 95% CI = 1.07–1.77; p = 0.01) and patients ...
Source: Genes - May 27, 2023 Category: Genetics & Stem Cells Authors: Ksenia A. Kobzeva Maria O. Soldatova Tatiana A. Stetskaya Vladislav O. Soldatov Alexey V. Deykin Maxim B. Freidin Marina A. Bykanova Mikhail I. Churnosov Alexey V. Polonikov Olga Y. Bushueva Tags: Article Source Type: research

The cost of warfarin treatment for stroke prevention in patients with nonvalvular atrial fibrillation in Russia from a collective perspective.
CONCLUSION: Although VKA drugs costs are relatively low, regular INR testing and consultations drive the economic burden for Russian NVAF patients treated with VKA. PMID: 28151036 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - February 4, 2017 Category: Health Management Tags: J Med Econ Source Type: research

Effectiveness of Faradic and Russian currents on plantar flexor muscle spasticity, ankle motor recovery, and functional gait in stroke patients
ConclusionAdding ES to exercises are associated with low to medium effect sizes (<0.5) in reducing spasticity and improving ankle ROM.
Source: Physiotherapy Research International - January 1, 2018 Category: Physiotherapy Authors: G. Shankar Ganesh, Ranjita Kumari, Monalisa Pattnaik, Patitapaban Mohanty, Chittaranjan Mishra, Parminder Kaur, Anandhi Dakshinamoorthy Tags: RESEARCH ARTICLE Source Type: research

Genes, Vol. 12, Pages 1938: Examination of Genetic Variants Revealed from a Rat Model of Brain Ischemia in Patients with Ischemic Stroke: A Pilot Study
A. Limborska Although there has been great progress in understanding the genetic bases of ischemic stroke (IS), many of its aspects remain underexplored. These include the genetics of outcomes, as well as problems with the identification of real causative loci and their functional annotations. Therefore, analysis of the results obtained from animal models of brain ischemia could be helpful. We have developed a bioinformatic approach exploring single nucleotide polymorphisms (SNPs) in human orthologues of rat genes expressed differentially under conditions of induced brain ischemia. Using this approach, we identified a...
Source: Genes - November 30, 2021 Category: Genetics & Stem Cells Authors: Andrey V. Khrunin Gennady V. Khvorykh Alexandra V. Rozhkova Evgeniya A. Koltsova Elizaveta A. Petrova Ekaterina I. Kimelfeld Svetlana A. Limborska Tags: Article Source Type: research

Incidence risks for cerebrovascular diseases and types of stroke in a cohort of Mayak PA workers
Radiat Environ Biophys. 2022 Feb 19. doi: 10.1007/s00411-022-00966-6. Online ahead of print.ABSTRACTIncidence risks for cerebrovascular diseases (CeVD) and some types of stroke in a cohort of 22,377 Russian Mayak nuclear workers chronically exposed to ionising radiation and followed up until the end of 2018 are reported. Among total 9469 cases of CeVD, 2078 cases were strokes that included 262 hemorrhagic strokes (HS) and 1611 ischemic strokes (IS). Data evaluation was performed with categorical and dose-response analyses estimating the relative risk (RR) and excess relative risk (ERR) per unit cumulative liver absorbed do...
Source: Radiation and Environmental Biophysics - February 19, 2022 Category: Physics Authors: Tamara V Azizova Maria B Moseeva Evgeniya S Grigoryeva Nobuyuki Hamada Source Type: research