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Total 40 results found since Jan 2013.

The Predictive Capacity of the Buffalo Concussion Treadmill Test After Sport-Related Concussion in Adolescents
Conclusion This study found that the ΔHR (HRt minus resting HR) correlated with duration of clinical recovery in participants who were prescribed relative rest or a placebo-stretching program but not for participants prescribed sub-threshold aerobic exercise. A ΔHR of ≤50 bpm on the BCTT was 73% sensitive and 78% specific for predicting delayed recovery in concussed adolescents prescribed the current standard of care (i.e., cognitive and physical rest). This has implications for planning team and school activities in adolescents who sustain SRC. Ethics Statement This study was carried out in acco...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

The dispersion of myocardial repolarization in ischemic stroke and intracranial hemorrhage
Markers of dispersion of myocardial repolarization have been proposed to identify the patients at higher risk of malignant arrhythmic events. The aim of the present study is to assess a possible association of the electrocardiografic (ECG) markers of the dispersion of repolarization with the type of stroke, involvement of insula, neurological severity (National Institutes of Health Stroke Scale, NIHSS score), and disability (modified Rankin Scale, mRS score) in patients with a cerebrovascular event.
Source: Journal of Electrocardiology - May 17, 2018 Category: Cardiology Authors: Alessandra Danese, Manuel Cappellari, Elia Pancheri, Giacomo Mugnai, Nicola Micheletti, Giampaolo Tomelleri, Monica Carletti, Giulia Turri, Vincenzo Marafioti, Salvatore Monaco, Bruno Bonetti, Paolo Bovi Source Type: research

Inflammation and Atrial Electrical Remodeling in Patients With Embolic Strokes of Undetermined Source
About one third of ischaemic strokes are classified as embolic strokes of undetermined source (ESUS). A silent atrial fibrillation (AF) may play a pathogenic role in these strokes and P wave dispersion (PWD), representing an electrocardiograph (ECG) predictor for paroxysmal AF, thereby a potential marker of covert cardioembolism, was found to be increased in cryptogenic stroke. Furthermore, current evidence links AF to inflammation: inflammatory markers, such as high-sensitive C-reactive protein (hsCRP), have been related to the development and persistence of AF, possibly by promoting atrial remodelling.
Source: Heart, Lung and Circulation - May 8, 2018 Category: Cardiology Authors: Maurizio Acampa, Pietro Enea Lazzerini, Francesca Guideri, Rossana Tassi, Andrea Lo Monaco, Giuseppe Martini Tags: Original Article Source Type: research

Inflammation and Atrial Electrical Remodelling in Patients With Embolic Strokes of Undetermined Source
About one third of ischaemic strokes are classified as embolic strokes of undetermined source (ESUS). A silent atrial fibrillation (AF) may play a pathogenic role in these strokes and P wave dispersion (PWD), representing an electrocardiographic (ECG) predictor for paroxysmal AF, thereby a potential marker of covert cardioembolism, was found to be increased in cryptogenic stroke. Furthermore, current evidence links AF to inflammation: inflammatory markers, such as high-sensitive C-reactive protein (hsCRP), have been related to the development and persistence of AF, possibly by promoting atrial remodelling.
Source: Heart, Lung and Circulation - May 7, 2018 Category: Cardiology Authors: Maurizio Acampa, Pietro Enea Lazzerini, Francesca Guideri, Rossana Tassi, Andrea Lo Monaco, Giuseppe Martini Tags: Original Article Source Type: research

Previous use of Statins and Atrial Electrical Remodeling in Patients with Cryptogenic Stroke
Source: Cardiovascular and Haematological Disorders - Drug Targets - March 2, 2018 Category: Cardiology Authors: Acampa, Maurizio Lazzerini, Pietro E. Guideri, Francesca Tassi, Rossana Lo Monaco, Andrea Martini, Giuseppe Tags: Research article Source Type: research

Previous use of statins and atrial electrical remodeling in patients with cryptogenic stroke.
CONCLUSIONS: Our results show lower PWD values in cryptogenic stroke patients previously treated with statins. These findings provide support to the hypothesis that statins may play a role in modulating atrial electrophysiological and structural properties, preventing the occurrence of a slowed and heterogeneous atrial conduction and finally, reducing the occurrence of AF. PMID: 29332603 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - January 17, 2018 Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research

Clinical outcomes of secondary prevention strategies for young patients with cryptogenic stroke and patent foramen ovale.
Conclusions The diagnosis of stroke in patients with PFO could be confirmed in 50% of cases only, underlining the importance of a multidisciplinary evaluation of these patients. A very low ischaemic recurrence rate was observed in the medical therapy group, suggesting that a personalized treatment based on a prespecified diagnostic algorithm yields good clinical results irrespective of the treatment modality. Given the low number of recurrences, larger cohorts may be needed to prove significant differences. PMID: 28705105 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - July 15, 2017 Category: Cardiology Tags: Acta Cardiol Source Type: research

The benefit of radiosurgery for ARUBA-eligible arteriovenous malformations: a practical analysis over an appropriate follow-up period.
CONCLUSIONS After a sensible follow-up period exceeding the latency period, there is a lower rate of stroke/death for patients with treated, unruptured AVMs with SRS than for patients with untreated AVMs. PMID: 28665253 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - June 30, 2017 Category: Neurosurgery Authors: Tonetti DA, Gross BA, Atcheson KM, Jankowitz BT, Kano H, Monaco EA, Niranjan A, Flickinger JC, Lunsford LD Tags: J Neurosurg Source Type: research

Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging
This study characterized inflammation in atherosclerosis using dual-targeted microparticles of iron oxide (DT-MPIO) as a magnetic resonance imaging (MRI) probe.
Source: Journal of Vascular Surgery - June 23, 2017 Category: Surgery Authors: Joyce M.S. Chan, Claudia Monaco, Marzena Wylezinska-Arridge, Jordi L. Tremoleda, Jennifer E. Cole, Michael Goddard, Maggie S.H. Cheung, Kishore K. Bhakoo, Richard G.J. Gibbs Tags: From bench to bedside Source Type: research

Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls.
Abstract People with severe mental illness (SMI) - schizophrenia, bipolar disorder and major depressive disorder - appear at risk for cardiovascular disease (CVD), but a comprehensive meta-analysis is lacking. We conducted a large-scale meta-analysis assessing the prevalence and incidence of CVD; coronary heart disease; stroke, transient ischemic attack or cerebrovascular disease; congestive heart failure; peripheral vascular disease; and CVD-related death in SMI patients (N=3,211,768) versus controls (N=113,383,368) (92 studies). The pooled CVD prevalence in SMI patients (mean age 50 years) was 9.9% (95% CI: 7.4-...
Source: World Psychiatry - May 13, 2017 Category: Psychiatry Authors: Correll CU, Solmi M, Veronese N, Bortolato B, Rosson S, Santonastaso P, Thapa-Chhetri N, Fornaro M, Gallicchio D, Collantoni E, Pigato G, Favaro A, Monaco F, Kohler C, Vancampfort D, Ward PB, Gaughran F, Carvalho AF, Stubbs B Tags: World Psychiatry Source Type: research

Left atrial appendage closure without general anaesthesia
Left atrial appendage closure is an important interventional procedure to prevent stroke in patients with permanent atrial fibrillation and contraindication to anticoagulants. Because it requires the patient not to move and the performance of a continuous and prolonged transoesophageal echocardiography (TEE), such procedure is usually performed under general anaesthesia. The risk of general anaesthesia in the elderly is associated with difficult airway control, malignant hyperthermia, residual neuromuscular block, high risk of postoperative pulmonary complications, and the risk of accelerated cognitive decline.
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 30, 2016 Category: Anesthesiology Authors: F Monaco, Evgeny Fominskiy, C D Votta, N Villari, R Capucci, JC Lopez-Delgado, V Camarda, M Baiardo Redaelli, A Oriani, A Zangrillo Source Type: research

Prolonged transesophageal echocardiography during percutaneous closure of the left atrial appendage without general anesthesia: the utility of the Janus mask.
CONCLUSION: Deep sedation with noninvasive ventilation may be a reasonable and safe alternative to general endotracheal anesthesia in patients requiring prolonged TEE for noninvasive cardiac procedures, including LAA closure. PMID: 27117991 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - April 25, 2016 Category: Anesthesiology Authors: Zangrillo A, Mazzone P, Votta CD, Villari N, Della Bella P, Monaco F Tags: Can J Anaesth Source Type: research

Prolonged QTc interval and insula in patients with ischemic stroke: Inductive or abductive reasoning?
While a great emphasis has been placed on pathophysiological mechanisms underlying the long QT syndromes (LQTS), both congenital and acquired forms, little attention has been focused on the mechanisms whereby a brain damage could induce changes in the QTc interval. Until now, there has been no precise explanation for the frequently observed relationship between acute cerebrovascular events and QTc interval prolongation. Many excellent studies with inductive reasoning proposed QTc effects of insular cortex stimulation [1,2] Few and controversial studies with abductive reasoning investigated an association between prolonged ...
Source: International Journal of Cardiology - August 4, 2014 Category: Cardiology Authors: Vincenzo Marafioti, Giulia Turri, Andrea Rossi, Salvatore Monaco, Vincenzo Carbone Tags: Letter to the Editor Source Type: research

Prolonged QTc interval and Insula in patients with ischemic stroke: Inductive or abductive reasoning?
While a great emphasis has been placed on pathophysiological mechanisms underlying the long QT syndromes (LQTS), both congenital and acquired forms, little attention has been focused on the mechanisms whereby a brain damage could induce changes in the QTc interval. Until now, there has been no precise explanation for the frequently observed relationship between acute cerebrovascular events and QTc interval prolongation. Many excellent studies with inductive reasoning proposed QTc effects of insular cortex stimulation [1,2] Few and controversial studies with abductive reasoning investigated an association between prolonged ...
Source: International Journal of Cardiology - August 4, 2014 Category: Cardiology Authors: Vincenzo Marafioti, Giulia Turri, Andrea Rossi, Vincenzo Carbone, Salvatore Monaco, Corrado Vassanelli Source Type: research