Transient left septal fascicular block in a patient with stable effort angina and critical proximal obstruction of left anterior descending coronary artery
We present a case in which the phenomenon occurred transiently, causing prominent anterior QRS forces, confirmed by coronary angiography. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 6, 2018 Category: Cardiology Authors: Andr és Ricardo Pérez-Riera, Raimundo Barbosa-Barros, Rodrigo Daminello-Raimundo, Luiz Carlos de Abreu, Kjell Nikus Source Type: research

Shift in the retrograde atrial activation sequence after radiofrequency catheter ablation in left variant atypical atrioventricular nodal reentrant tachycardia
We describe an unusual case of “left-variant” atypical AVNRT, where change in the retrograde earliest atrial activation site (REAAS) at the coronary sinus (CS) following radiofrequency catheter ablation (RFCA) was observed. Our observation suggests that the REAAS, that is, the left AVN connections, could participate in the formation of the reentrant circuit of “left-variant” atypical AVNRT. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 6, 2018 Category: Cardiology Authors: Takashi Nakashima, Nobuhiro Takasugi, Yuki Sahashi, Tomoki Kubota, Masanori Kawasaki Source Type: research

Poor reliability of P-wave terminal force V1 in ischemic stroke
We examined the factors that contribute to the reliability of PTFV1 and its association with ischemic stroke. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 6, 2018 Category: Cardiology Authors: Jithin K. Sajeev, Anoop N. Koshy, Helen Dewey, Jonathan M. Kalman, Manini Bhatia, Louise Roberts, Jennifer C. Cooke, Tanya Frost, Rachel Denver, Andrew W. Teh Source Type: research

The role of heart rate variability, heart rate turbulence, and deceleration capacity in predicting cause-specific mortality in chronic heart failure
The volume of regional denervated myocardium (D-M) on positron emission tomography has been recently suggested as a strong independent predictor of cause-specific mortality from sudden cardiac arrest (SCA) in chronic heart failure. We sought to evaluate whether ECG indices of global autonomic function predict risk of SCA to a similar degree as regional D-M. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 6, 2018 Category: Cardiology Authors: Salah S. Al-Zaiti, Grzegorz Pietrasik, Mary G. Carey, Mohammad Alhamaydeh, John M. Canty, James A. Fallavollita Source Type: research

Unexpected reappearance of ST elevation in the anterior precordial leads shortly after an acute anterior myocardial infarction
Brugada syndrome (BrS) is an inherited congenital electrical abnormality characterized by right precordial ST-segment elevation that predisposes patients with apparent structurally normal hearts to malignant ventricular arrhythmias and sudden cardiac death. The diagnosis of BrS is based on typical ECG characteristics along with symptoms and familial history. Brugada phenocopy (BrP) encompasses a number of clinical entities characterized by ECG patterns that, while identical to true BrS, are elicited by various clinical conditions (i.e., metabolic conditions, mechanical compression, myocardial ischemia, myocardial/pericardi...
Source: Journal of Electrocardiology - November 5, 2018 Category: Cardiology Authors: Antonio Lippolis, Paola Maria Buzzi, Ilaria Jane Romano, Annalisa De Concilio, Francesco Gentile Source Type: research

Association between T-wave discordance and the development of heart failure in left bundle branch block patients: Results from the Copenhagen ECG study
We examined the association between discordant T-waves and high QRS-T angles for heart failure development in primary care LBBB patients. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 5, 2018 Category: Cardiology Authors: Johannes Riis Jensen, Kristian Kragholm, Karoline Willum B ødker, Rikke Mortensen, Claus Graff, Adrian Pietersen, Jonas Bille Nielsen, Christoffer Polcwiartek, Bhupendar Tayal, Christian Torp-Pedersen, Peter Søgaard, Steen Møller Hansen Source Type: research

Continuous heart rate monitoring for automatic detection of atrial fibrillation with novel bio-sensing technology
Asymptomatic atrial fibrillation [AF] is an important cause of fatal or disabling stroke. A continuous heart-rate monitoring device, comfortable enough to be worn continuously and reliable enough to detect AF, would allow for prompt initiation of anticoagulation therapy to prevent stroke. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 1, 2018 Category: Cardiology Authors: Aviram Hochstadt, Ehud Chorin, Sami Viskin, Arie Lorin Schwartz, Natan Lubman, Raphael Rosso Source Type: research

Case report: Apical variant hypertrophic cardiomyopathy simulating an acute inferior myocardial infarction
We present a female patient who arrived to the emergency department with chest pain without known medical history at the time of consultation. Considering her risk factors and electrocardiographic findings, it was decided to perform a coronary catheterization under the suspicion of acute myocardial infarction. The catheterization and another studies was negative for coronary artery disease. Additional studies were conclusive for apical variant hypertrophic cardiomyopathy or Yamaguchi syndrome. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 1, 2018 Category: Cardiology Authors: Juan Morales, Miller Giraldo Source Type: research

Electrocardiographic changes after implantation of a left ventricular assist device – Potential implications for subcutaneous defibrillator therapy
Implantation of a left ventricular assist device (LVAD) leads to a diverse spectrum of changes on the twelve-lead surface electrocardiogram (ECG). We aimed to elucidate the changes of the surface ECG in patients after LVAD implantation potentially impacting ECG based screening tests of subcutaneous implantable cardioverter-defibrillators (S-ICD). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - November 1, 2018 Category: Cardiology Authors: Christos Zormpas, Johanna Mueller-Leisse, Thorben Koenig, Jan D. Schmitto, Christian Veltmann, David Duncker Source Type: research

The predictive value of aVR in determining the infarct related artery during primary percutaneous coronary intervention
Isolation of infract related artery and timely revascularisation remains vital in the setting of primary percutaneous coronary intervention. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 30, 2018 Category: Cardiology Authors: Ayman Gaballa, Wala Farid, Ahmad Al-Kersh, Rajesh Rajan, Mohammed Al Jarallah Source Type: research

Long –term prognostic significance of terminal QRS distortion on patients with stemi and its correlation with the GRACE scoring system
The standard 12-lead electrocardiogram (ECG) continues to serve as the most widely used tool in the diagnosis and risk stratification of patients with acute ST-segment elevation myocardial infarction (STEMI) and several new ECG parameters have been shown to be useful in determining patients at higher risk [1 –3]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 29, 2018 Category: Cardiology Authors: Ahmet Y ılmaz, Kenan Demir, Recep Karataş, Mustafa Çelik, Ahmet Avcı, Fikret Keleş, Ahmet Erseçgin, Nazif Aygül, Bülent Behlül Altunkeser Source Type: research

Automatic atrial fibrillation and flutter detection by a handheld ECG recorder, and utility of sequential finger and precordial recordings
Handheld ECG recorders may have algorithms which automatically inform the user of presence of arrhythmia. The main objectives of this study were to evaluate the accuracy of the arrhythmia diagnosis algorithm of Beurer ME90 recorder to diagnose atrial fibrillation (AF)/flutter, and to evaluate whether recording technique (finger versus precordial) affects diagnostic performance. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 18, 2018 Category: Cardiology Authors: Rita Brito, Louis-Paulin Mondouagne, Carine Stettler, Christophe Combescure, Haran Burri Source Type: research

Prevalence of junctional ST-depression with tall symmetrical T-waves in a pre-hospital field triage system for STEMI patients
The prevalence of the junctional ST-depression with tall symmetrical T-waves in a field triage system for ST-Elevation Myocardial Infarction (STEMI) is unknown. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 18, 2018 Category: Cardiology Authors: Ruben W. de Winter, Rob Adams, Giovanni Amoroso, Yolande Appelman, Lucia ten Brinke, Bart Huybrechts, Pieternel van Exter, Robbert J. de Winter Source Type: research

The optimal management of patient with permanent atrial fibrillation and heart failure with reduced ejection fraction – The permanent His-bundle pacing is a solution. A case report
We present a case of 69-years-old male with AF, worsening HF and high burden of RV pacing. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 16, 2018 Category: Cardiology Authors: Bartosz Skonieczny, Aleksandra Gajek, Piotr Str ózik, Jacek Zawadzki, Jakub Adamowicz, Jacek Gajek, Agnieszka Slawuta Source Type: research

Ideal admission electrocardiographic parameters in STEMI: What else do we need to learn?
We read with great interest the article entitled ‘Prognosis and first diagnostic ECG in STEMI patients referred to the emergency medical system for primary PCI’ by Meloni et al. [1]. We want to thank the authors for their investigation of the prognostic association between Q wave presence and in-hospital mortality in patients with all types of ST-segment elevation myocardial infarction (STEMI). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 13, 2018 Category: Cardiology Authors: Mert İlker Hayıroğlu, Ceyhan Türkkan, Ahmet İlker Tekkeşin Source Type: research

A novel signal-averaged electrocardiogram and an ambulatory-based signal-averaged electrocardiogram show strong correlations with conventional signal-averaged electrocardiogram in healthy subjects: A validation study
This study aimed to validate the novel SAECG and the novel ambulatory-based SAECG devices by comparison with the conventional SAECG device. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 10, 2018 Category: Cardiology Authors: Kenichi Hashimoto, Bonpei Takase, Masaaki Nagashima, Yuji Kasamaki, Hiroaki Shimabukuro, Masayoshi Soma, Tomohiro Nakayama Tags: Review Source Type: research

Association of obesity phenotypes with electrocardiographic left ventricular hypertrophy in the general population
Increasing evidence doubts the benign nature of metabolically healthy obesity (MHO). An investigation of the association of MHO and other obesity phenotypes with electrocardiographic left ventricular hypertrophy (ECG-LVH), a risk factor for cardiovascular disease (CVD), can give insight into the pathophysiological basis for increased risk of CVD linked to these phenotypes. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 9, 2018 Category: Cardiology Authors: Muhammad Imtiaz Ahmad, Yabing Li, Elsayed Z. Soliman Source Type: research

Atrial flutter and embolic risk: The relationship between atrial flutter cycle length and left atrial appendage function
The potential for thromboembolism in atrial flutter (AFL) is different from atrial fibrillation. AFL cycle length (AFL-CL) may be related to reduced left atrial appendage (LAA) function. Very rapid AFL-CL can lead to mechanical and electrophysiological disorders that contribute to lower LAA emptying velocity (LAEV). The aim of this study is to relate atrial flutter cycle length with LAEV and its role in thrombogenesis. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 8, 2018 Category: Cardiology Authors: Ana Paula Susin Os ório, Luciana Eder Martins Barros Simoni, Antonio Lessa Gaudie Ley, Grasiele Bess de Oliveira, Roberto Tofani Santanna, Marcelo Haertel Miglioranza, Gustavo Glotz de Lima, Vidal Essebag, Tiago Luiz Luz Leiria Source Type: research

Differences in amiodarone efficacy in relation to ejection fraction and basal rhythm in patients with implantable cardioverter defibrillators
This study aimed to clarify the association between AF and VAs and to investigate the effect of amiodarone on the incidence of VAs in patients with implantable cardioverter defibrillators (ICDs). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 8, 2018 Category: Cardiology Authors: Tetsuya Watanabe, Koichi Inoue, Kazunori Kashiwase, Takanao Mine, Keiji Hirooka, Ryu Shutta, Hiroya Mizuno, Yuji Okuyama, Yasushi Sakata, Shinsuke Nanto, SATISFACTION Investigators Source Type: research

Type 1 Brugada phenocopy in a patient with acute pericarditis
We herein describe a case of an acute pericarditis, in which type 1 Brugada phenocopy (BrP) was documented. The patient was referred to our hospital due to severe chest pain. The twelve-lead electrocardiogram (ECG) on admission showed type 1 Brugada ECG pattern (coved-type) in the precordial leads. Echocardiography only showed mild pericardial effusion. However, his ST segment elevation returned to normal and chest discomfort disappeared 3  weeks later. Our report addresses the possibility that the coved-type ST-segment elevation cannot be a sensitive finding for Brugada syndrome (BrS). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 8, 2018 Category: Cardiology Authors: Manli Yu, Qin Zhang, Xinmiao Huang, Xianxian Zhao Source Type: research

Ventricular fibrillation undersensing to calculate a safety threshold for baseline rhythm R-wave amplitudes
We have read with great interest the study of Mark L. Brown [1], on ventricular fibrillation (VF) sensing using Medtronic implantable cardioverter defibrillators (ICDs). Dr. Brown describes the ventricular sensing process performed on Medtronic ICDs, but unfortunately his report does not show further data processed with proprietary filters. Dr. Brown does criticize our recent report [2], in which we documented that baseline rhythm (BR) R-wave amplitudes ≤2.5 mV (Interquartile range: 2.3, 2.8) show potential for high undersensing rates of VF electrograms dropping below the minimum nominal sensitivity during spontaneous...
Source: Journal of Electrocardiology - October 8, 2018 Category: Cardiology Authors: David Filgueiras-Rama, Jos é María Lillo-Castellano, Jorge G. Quintanilla Source Type: research

Does prematurity unmask disease?
A 55  year old man with a history of asthma, chronic obstructive pulmonary disease, hypertension, diabetes, current smoking, and cocaine use presented to the emergency department with dyspnea on exertion, wheezing, and a dry cough for 4 days. On physical examination, his vital signs were normal, ches t examination revealed audible expiratory wheezing, and cardiovascular examination was normal. An electrocardiogram (ECG) was obtained (Fig. 1A). What is the diagnosis? Is any workup required? (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 8, 2018 Category: Cardiology Authors: Adam Oesterle, Simon Ermakov, Nora Goldschlager Source Type: research

Electrocardiographic characteristics before and after correction of right-sided congenital heart defects in children and its relation to prognosis
Congenital heart defects are the most common birth defects and occur in 0.8% of all live births. Nowadays, patients with congenital heart defects survive with usually many event-free years despite abnormal cardiac hemodynamics. However, most patients still need life-long follow-up and main factors for morbidity and mortality in these patients are cardiac failure, arrhythmias or pulmonary hypertension (PH) [1]. The electrocardiogram (ECG) is a noninvasive, widely-used, inexpensive tool that can be used during long-term follow-up of these patients, particularly in order to help predict occurrence of rhythm disorders and sudd...
Source: Journal of Electrocardiology - October 4, 2018 Category: Cardiology Authors: Vivian P. Kamphuis, Daphne Raad, Martina Nassif, Cees A. Swenne, Nico A. Blom, Arend D.J. ten Harkel Tags: Review Source Type: research

A larger vectorcardiographic QRS area is associated with left bundle branch block and good prognosis in patients with cardiac resynchronization therapy
The association between the vectorcardiographic QRS area, bundle branch pattern and clinical long-term prognosis in patients who have undergone cardiac resynchronization therapy (CRT) has been unclear. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 4, 2018 Category: Cardiology Authors: Tomoyuki Kabutoya, Yasushi Imai, Yasuhiro Yokoyama, Ayako Yokota, Tomonori Watanabe, Takahiro Komori, Kazuomi Kario Source Type: research

Electrocardiogram algorithms used to differentiate wide complex tachycardias demonstrate diagnostic limitations when applied by non-cardiologists
This study aimed to determine the diagnostic efficacy of the Vereckei aVR and Brugada algorithms when applied by NCs. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - October 3, 2018 Category: Cardiology Authors: Adam M. May, Jorge A. Brenes-Salazar, Christopher V. DeSimone, Vaibhav R. Vaidya, Bradley W. Ternus, David O. Hodge, Grace Lin, Siva K. Mulpuru, Abhishek J. Deshmukh, Peter A. Noseworthy, Peter A. Brady Source Type: research

Flecainide overdose presenting with long QT and acute Takotsubo cardiomyopathy
Takotsubo cardiomyopathy is a rare type of reversible cardiomyopathy characterized by the development of left-ventricular (LV) apical ballooning in the absence of significant coronary arterial disease. Initially described in Japan during the 1990s [1], this diagnosis has become more common with advanced cardiac imaging modalities and increasing awareness. The etiology and pathogenesis of Takotsubo remain unclear, but it often follows extreme emotional or physical stress [1]. Catecholamine-induced myocardial stunning and autonomic dysfunction have becoming leading hypotheses [2]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 27, 2018 Category: Cardiology Authors: George Bodziock, Chadwick Armstrong, Jay Montgomery Source Type: research

Triangular “shark fin-like” ST modification in takotsubo syndrome: Challenging the concept of ST-elevation patterns without coronary occlusion?
We read with great interest the article by Cipriani et al. entitled “The electrocardiographic ‘triangular QRS-ST-T waveform’ pattern in patients with ST-segment elevation myocardial infarction: incidence, pathophysiology and clinical implications” [1]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 24, 2018 Category: Cardiology Authors: Nicola Tarantino, Francesco Santoro, Natale Daniele Brunetti Source Type: research

Ejection fraction in left bundle branch block is disproportionately reduced in relation to amount of myocardial scar
The relationship between left ventricular (LV) ejection fraction (EF) and LV myocardial scar can identify potentially reversible causes of LV dysfunction. Left bundle branch block (LBBB) alters the electrical and mechanical activation of the LV. We hypothesized that the relationship between LVEF and scar extent is different in LBBB compared to controls. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 17, 2018 Category: Cardiology Authors: Jimmy Axelsson, Bj örn Wieslander, Robert Jablonowski, Igor Klem, Robin Nijveldt, Erik B. Schelbert, Peder Sörensson, Andreas Sigfridsson, Uzma Chaudhry, Pyotr G. Platonov, Rasmus Borgquist, Henrik Engblom, David G. Strauss, Håkan Arheden, Brett D. Atw Source Type: research

Pre-excitation induced ventricular dysfunction and successful berlin heart explantation after accessory pathway ablation
A 13  kg, 20 month-old, Caucasian girl, presented with cardiomyopathy, biventricular dysfunction and pre-excitation on electrocardiogram. She had normal intracardiac anatomy with severely dilated left ventricle and severely diminished biventricular function (Fig. 1). She was treated with milrinone an d epinephrine infusions, mechanical ventilation and listed for heart transplant. She underwent Berlin Heart EXCOR biventricular assist device (BiVAD) placement (30 ml LVAD and 25 ml RVAD pumps). No supraventricular tachycardia (SVT) was inducible or noted during her hospitalization. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 17, 2018 Category: Cardiology Authors: Utkarsh Kohli, Karen L. Pumphrey, Aziez Ahmed, Srikant Das Source Type: research

Prognosis and first diagnostic ECG in STEMI patients referred to the emergency medical system for primary PCI
When assessing time to reperfusion in ST-segment elevation myocardial infarction (STEMI) patients, we refer to time points which may be objectively obtained, such as the Emergency Medical System (EMS) call, the time of the first qualifying electrocardiogram (ECG), the door time or the time of cardiac catheterization laboratory (cath-lab) in which recanalization of the culprit coronary is attained. These time points are currently used to measure the system delay in delivering primary percutaneous coronary intervention (PCI) [1]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 11, 2018 Category: Cardiology Authors: Luigi Meloni, Maria Francesca Marchetti, Cristina Cacace, Michela Congia, Roberta Scotto, Piero Caddeo, Roberta Montisci Source Type: research

Prognostic value of electrocardiographic time intervals and QT rate dependence in hypertrophic cardiomyopathy
Preventing sudden cardiac death (SCD) is one of the main goals in hypertrophic cardiomyopathy (HCM). Many variables have been proposed, however the European and American guidelines do not incorporate any ECG or Holter monitoring derived variables other than the presence of ventricular arrhythmia in their risk stratification models. In the present study we evaluated electrocardiographic parameters in risk stratification of HCM. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 11, 2018 Category: Cardiology Authors: Tomas Robyns, Dieter Nuyens, Hua Rong Lu, David J. Gallacher, Bert Vandenberk, Christophe Garweg, Joris Ector, Efstathios Pagourelias, Johan Van Cleemput, Stefan Janssens, Rik Willems Source Type: research

Atypical advanced interatrial blocks: Definition and electrocardiographic recognition
The diagnosis of advanced interatrial block (A-IAB) is done by surface ECG analysis when the P-wave ≥120 ms with biphasic (±) morphology in leads II, III and aVF. In this brief communication, we advance a new concept involving atypical patterns of A-IAB due to changes about the morphology or duration of the P-wave. It remains to be determined its real prevalence in different clinical scenario s, and whether these atypical ECG patterns should be considered as predictors of atrial fibrillation/stroke. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 11, 2018 Category: Cardiology Authors: Antoni Bayes de Luna, Luis Alberto Escobar-Robledo, David Aristizabal, Danilo Weir Restrepo, Guiomar Mendieta, Albert Mass ó van Roessel, Roberto Elosua, Antoni Bayés-Genís, Manuel Martínez-Selles, Adrian Baranchuk Source Type: research

An algorithm for the differentiation of the infarct territory in difficult to discern electrocardiograms
In this study, we sought ECG clues which may facilitate discriminating (1) MI location and then (2) culprit artery in patients with difficult-to-discern ECGs. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 11, 2018 Category: Cardiology Authors: Emrah Bozbeyo ğlu, Emre Aslanger, Özlem Yıldırımtürk, Barış Şimşek, Can Yücel Karabay, Ayça Türer, Ömer Kozan, Muzaffer Değertekin Source Type: research

More on the pacemaker ECG in severe hyperkalemia
We thank Tomcs ányi and Bózsik [1] for their interest in our work [2] and allowing us to further elaborate on electrocardiographic (ECG) signs of severe hyperkalemia. We agree that in patients with pacemakers, conventional ECG markers of hyperkalemia are frequently lacking and therefore, any sign that can lead t o this important clinical diagnosis is welcome. As Tomcsányi and Bózsik have pointed out, well established manifestations include marked widening of the paced QRS complexes [3] as well as any type of failure of pacemaker sensing and capture [4]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 11, 2018 Category: Cardiology Authors: Laszlo Littmann, Michael A. Gibbs Source Type: research

Malignant ventricular tachycardia and cardiac arrest induced by a micra ™ leadless pacemaker
We present a case of a patient who had a leadless pacemaker implanted, which induced ventricular tachycardia and cardiac arrest during hospitalization. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 8, 2018 Category: Cardiology Authors: Flemming Javier Olsen, Sofie H øjlund, Michael Dilou Jacobsen Source Type: research

ECGI in atrial fibrillation: A clinician's wish list
Have we a challenge of credibility in the invasive treatment of atrial fibrillation (AFIB)? The incidence of AFIB in the European Union (EU) is about 600,000 cases per year, while only 100,000 get an invasive treatment with a failure rate of close to 40%. Those that remain in AFIB need two times more hospitalizations and three times more re-hospitalizations. AFIB accounts for over 1% of the EU health care costs. Too many patients are not referred and the indication rates of cardiac ablation are inexplicably variable throughout the EU. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 6, 2018 Category: Cardiology Authors: Joaquin Azpilicueta, Mikhail Chmelevsky, Danila Potyagaylo Source Type: research

Editorial Board
(Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - September 1, 2018 Category: Cardiology Source Type: research

The role of mexiletine in the management of long QT syndrome
Congenital long QT syndrome (LQTS) is a hereditary cardiac disorder characterized by QT-interval prolongation and T-wave abnormalities on electrocardiogram (ECG), and is associated with an increased risk of torsade de pointes and sudden cardiac death. Beta-blocker medication is effective in most patients except those with a very slow heart rate. Increased late sodium currents (INa-L) can result in bradycardia-dependent QT prolongation. Mexiletine, an inhibitor of INa-L, is not only effective in treating type-3 LQTS, but also shows the promise in managing LQTS patients of other genotypes with markedly prolonged QT interval ...
Source: Journal of Electrocardiology - August 30, 2018 Category: Cardiology Authors: Guoliang Li, Li Zhang Tags: Review Source Type: research

Persistent but reversible advanced atrio-ventricular block in a heart transplant man induced by dobutamine stress echocardiography
We report a heart transplant patient with high cardiovascular risk who developed symptomatic advanced AV block during DSE which persisted after termination of dobutamine administration, necessitating pacemaker implantation. To our knowledge, this is the first published case of persistent high grade AV block in a heart transplant patient induced by DSE. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 27, 2018 Category: Cardiology Authors: M. Kyriakopoulou, D.C. Mirica, R. Casado-Arroyo Source Type: research

Prevalence of atrial fibrillation with insertable cardiac monitors in cryptogenic stroke: A single-center experience
We describe a single-center experience for AF detection among CS patients receiving ICMs upon discharge after the index stroke event and attempt to identify predictors for AF detection. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 25, 2018 Category: Cardiology Authors: Ganesh Asaithambi, Jane E. Monita, M. Ramu Annamalai, Bridget M. Ho, Emily H. Marino, Sandra K. Hanson Source Type: research

What is ventricular fibrillation undersensing?
Ventricular fibrillation (VF), uninterrupted, is fatal within minutes. Implantable cardioverter defibrillators (ICDs) sense ventricular electrograms (EGMs) during VF and detect the VF rhythm (a sequence of VF sensed events) to deliver a shock to terminate VF and save lives. VF sensing and detection in Medtronic ICDs has been reported to be highly sensitive. However, Castellano et al. reported that Medtronic ICDs have the potential for high levels of undersensing in VF, sufficient to underdetect VF and withhold life-saving therapy. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 24, 2018 Category: Cardiology Authors: Mark L. Brown Source Type: research

Prognostic value of frontal QRS-T angle in patients undergoing myocardial revascularization or cardiac valve surgery
An abnormal frontal QRS-T angle (fQRSTa) is associated with increased risk of death in primary and secondary cardiovascular prevention. The aim of this study was to evaluate the fQRSTa prognostic role in patients undergoing myocardial revascularization and/or cardiac valve surgery. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 23, 2018 Category: Cardiology Authors: Davide Lazzeroni, Matteo Bini, Umberto Camaiora, Paolo Castiglioni, Luca Moderato, Pietro Tito Ugolotti, Lorenzo Brambilla, Valerio Brambilla, Paolo Coruzzi Source Type: research

Wavelet leader multifractal analysis of heart rate variability in atrial fibrillation
Accurate and timely detection of atrial fibrillation (AF) episodes is important in primarily and secondary prevention of ischemic stroke and heart-related problems. In this work, heart rate regularity of ECG inter-beat intervals was investigated in episodes of AF and other rhythms using a wavelet leader based multifractal analysis. Our aim was to improve the detectability of AF episodes. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 22, 2018 Category: Cardiology Authors: Kais Gadhoumi, Duc Do, Fabio Badilini, Michele M. Pelter, Xiao Hu Source Type: research

Association between typical electrocardiographic abnormalities and NT-proBNP elevation in a large cohort of patients with Chagas disease from endemic area
Chagas cardiomyopathy is the most harmful complication of Chagas disease. The electrocardiogram is a well-studied exam and has been considered an important tool for detection and evaluation of Chagas cardiomyopathy since the first years of its description. Many of its abnormalities have been described as associated with a worse prognosis. Serum BNP levels were described as inversely related to the left ventricular ejection fraction and as an independent predictor of death. It was not reported how electrocardiographic alterations correlate to NT-proBNP and its analog. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 22, 2018 Category: Cardiology Authors: Bruno Oliveira de Figueiredo Brito, Marcelo Martins Pinto Filho, Clareci Silva Cardoso, Claudia Di Lorenzo Oliveira, Ariela Mota Ferreira, Lea Campos de Oliveira, Paulo Gomes, Maria do Carmo Pereira Nunes, Ester Cerdeira Sabino, Antonio Luiz Pinho Ribeiro Source Type: research

Brugada phenocopy associated with left ventricular aneurysm
We describe the case of a 41-year-old male who exhibited BrP due to a left ventricular aneurysm in the context of chronic coronary artery disease. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 22, 2018 Category: Cardiology Authors: Enes Elvin Gul, Sohaib Haseeb, Osama Al Amoudi, Adrian Baranchuk Source Type: research

A method to extract realistic artifacts from electrocardiogram recordings for robust algorithm testing
We present a method to estimate device-specific signal noise and artifacts from ECG records. This method can be applied to obtain noise estimates from healthy subjects on any ECG lead, allowing a simple device-specific recording. The proposed approach is assessed using the MIT-BIH Noise Stress Test Database recordings combined with simulated ECGs. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Loriano Galeotti, Christopher G. Scully Source Type: research

A new criterion to differentiate atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia: Combined AVR criterion
A combined aVR criterion is described as the presence of a pseudo r ′ wave in aVR during tachycardia in patients without r′ wave in aVR in sinus rhythm and/or a ≥50% increase in r′ wave amplitude compared to sinus rhythm in patients with r′ wave in the basal aVR lead. We aimed to investigate the use of combined aVR criterion in differential diagnosis of at rioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reciprocating tachycardia (AVRT). (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Abdullah Orhan Demirta ş, Yahya Kemal Icen, Onur Kaypaklı, Hasan Koca, İlker Ünal, Zikret Köseoğlu, Durmus Yıldıray Sahin, Mevlut Koc Source Type: research

FDA perspective on assessing the clinical benefit of cardiac resynchronization and implantable cardioverter-defibrillator devices
Over the past couple of decades, the clinical benefit of implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT) devices has been shown in several large randomized controlled trials [1 –5]. ICDs have been shown to reduce the risk of sudden cardiac death and ventricular fibrillation, and CRTs have been shown to benefit patients with heart failure in terms of improvements in cardiac function, with a reduction in mortality and heart failure hospitalizations. Given the rapid pace of technological advances in electrophysiology devices over the last decade and the widespread use of these ...
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Kimberly A. Selzman Source Type: research

The role of epicardial fat as a local mediator of atrial fibrosis
Atrial fibrillation (AF) is the most common arrhythmia in the clinical setting and associated with severe consequences. In recent years, studies on the fundamental underlying pathophysiology of AF revealed electrical, contractile and structural remodeling were synergistic contributors to AF substrate. Fibrosis was the intersection point for different remodeling processes with common endpoint of promoting and maintaining AF [1]. Despite the fact that myocardial ischemia was consistently found to be the major preceding event for fibrosis in ventricular myocardium, there is much weaker evidence for atrial ischemia causing atr...
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: G öksel Çinier, Emrah Bozbeyoğlu, Ahmet İlker Tekkeşin Source Type: research

Reply to the letter to the editor: Successful catheter ablation of ventricular fibrillation
We have recently read with great interest the article by Gul EE, entitled ‘Successful catheter ablation of ventricular fibrillation: Which premature ventricular complexes should we target?’ which was published in the last issue of the Journal of Electrocardiology [1]. First of all, we would like to thank the author for his interest in our case report. We aimed to prov ide a valuable clinical insight for the literature with this case which is difficult to manage and treat [2]. (Source: Journal of Electrocardiology)
Source: Journal of Electrocardiology - August 18, 2018 Category: Cardiology Authors: Abdulkadir Uslu, Ahmet Guner, Sabahattin Gunduz Source Type: research