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Total 184 results found since Jan 2013.

A Novel Atrial Fibrillation Evaluation Modelling Solution For NHS
Approximately every fifth stroke in UK is due to AF and costs the UK National Health Service are between $12,000 and $17,500 per stroke. The aim of this study was to undertake a retrospective health economic analysis of the cost-effectiveness and implications related to opportunistic Atrial Fibrillation (AF) screening in primary care and the detection of previously undiagnosed AF cases in patients, and create a novel modelling solution that can empower individual users and organisations in England, Wales and Northern Ireland in their decision making, technology assessment, comparison of various anticoagulation d rug group...
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: G Xydopoulos, R Fordham, Z Khanbai Source Type: research

This Woman Woke Up With a British Accent. Here ’s What to Know About Foreign Accent Syndrome
This article originally appeared on Health.com
Source: TIME: Health - February 13, 2018 Category: Consumer Health News Authors: Jamie Ducharme / Health.com Tags: Uncategorized healthytime Mental Health/Psychology onetime Source Type: news

Design and rationale of the Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study
This study details the design of the Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study – a postauthorization observational study, which is part of the postapproval plan for edoxaban agreed with the European Medicines Agency. Methods The ETNA-AF-Europe study (Clinicaltrials.gov: NCT02944019) is a multicenter, prospective, observational study that enrolled 13 980 patients with atrial fibrillation treated with edoxaban from 852 sites across 10 European countries (Austria, Belgium, Germany, Ireland, Italy, the Netherlands, Portugal, Spain, Switzerland,...
Source: Journal of Cardiovascular Medicine - January 3, 2019 Category: Cardiology Tags: Research articles: Trial design Source Type: research

Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?
This study demonstrated unaltered vascular conductance in response to lumbar sympathetic stimulation in CIH-exposed rats. Aortic compliance was increased and estimated blood volume was unchanged in CIH-exposed rats. Increased blood pressure was related to an increase in cardiac output, which was confirmed by echocardiography (Lucking et al., 2014). It is suggested therefore that hypertension in the CIH model can be evoked by over-excitation of the cardiac arm of sympathetic nervous system (SNS), even before mechanisms of enhanced peripheral vasoconstriction and endothelial dysfunction are initiated (Naghshin et al., 2009)....
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain
This study was carried out in accordance with the recommendations of National Animal Welfare Authority, Ireland. The protocol was approved by the Animal Ethical Committee Trinity College Dublin and HPRA.Author ContributionsAS performed the experiments and wrote the paper; KH provided assistance in the design and analysis of the RNAseq experiment; DT contributed to sample extraction and establishment of the colony; and DT and MG designed and supervised all the parts of the research and the writing of the manuscript.FundingThe study was funded by the Wellcome Trust Grant WT079408/C/06/Z issued to MG, and by an SFI FN Funded ...
Source: Frontiers in Psychiatry - April 29, 2019 Category: Psychiatry Source Type: research

164 Dementia, a Familial Affair
ConclusionThis case highlights the importance of genetics shaping phenotypes and that consideration should always be given to a full relevant family history.  It also shows a rare case of rapidly progressive dementia confirmed due to CJD with a likely underlying familial predisposition.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

207 Acute Incidence of Disease at Elevated Levels of Fine Particulate Matter (PM2.5) in Dublin, Ireland
ConclusionControls need to be brought in to ensure that PM2.5 does not exceed a 50μg/m3 level due to the increase in disease incidence associated with same. The urban burning of solid fuels should be severely restricted.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

268 Can the Swallow Screening Component of a Frailty Assessment be Used to Reliably Direct Clinical Dysphagia Assessment Referrals?
ConclusionA trained interdisciplinary frailty team can reliably screen for and identify risk of dysphagia. This indicates a potential for use of more standardised swallow screening protocols beyond the post stroke population into a broader cohort of patients.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

33 “Striking Back Against Stroke”
ConclusionThis is an ongoing process which continues to ultimately improve patient outcomes.“Time is Brain”
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

Post-acute organisational audit report
Sentinel Stroke National Audit Programme (SSNAP) - Based on data from 664 post-acute services, this report describes the organisation of post-acute stroke care in England, Wales, Northern Ireland, the Isle of Man and Jersey as of 1 April 2021. Overall, the report found some improvements when compared to 2015, including the fact that 99 per cent of services have access to an occupational therapist, physiotherapist and rehab assistant (95 per cent in 2015).ReportMore detail
Source: The Kings Fund - Health Management Specialist Collection - December 13, 2021 Category: Health Management Authors: The King ' s Fund Library Tags: NHS performance and productivity Source Type: news

EP47* Investigation of current and novel treatment strategies for ICA and MCA occlusions in an in-vitro thrombectomy model
ConclusionsThe novel 0.088’’ aspiration catheter achieves the best FPE rates in both ICA and MCA occlusions. In terms of existing techniques, ADAPT is more effective in the MCA, while the stentrievers provide a benefit in the ICA.ReferencesHafeez MU, Kan P, Srivatsan A, Moore S, Jafari M, DeLaGarza C, et al. Comparison of first-pass efficacy among four mechanical thrombectomy techniques: a single-center experience. World Neurosurgery 2020;144:e533–e40.Gershon BS, Bageac DV, Shigematsu T, Majidi S, De Leacy R. Republished: first clinical report of aspiration through a novel 0.088-inch catheter positioned i...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Nogueira, R., Thornton, J., Mullins, L., Fitzgerald, S. Tags: Treatment Source Type: research

Osteoporotic fracture admissions compared to other major medical admissions in Irish public hospitals
ConclusionOsteoporotic fractures represent a large and rapidly increasing illness burden amongst older Irish adults, with substantial care requirements and the resulting onus on our healthcare system. Urgent action is needed to address this public health issue and the services for those at risk of fracture.
Source: Archives of Orthopaedic and Trauma Surgery - December 17, 2022 Category: Orthopaedics Source Type: research

Charity claims failure of protection over junk food adverts
Northern Ireland Chest, Heart and Stroke says watchdog 'unable’ to regulate industry online    
Source: The Irish Times - Health - April 29, 2013 Category: Consumer Health News Source Type: news

The association of cold weather and all-cause and cause-specific mortality in the island of Ireland between 1984 and 2007
Conclusions: The study findings indicated strong cold weather-mortality associations in the island of Ireland; these effects were less persistent, and for CVD mortality, smaller in NI than in the ROI. Together with suggestive differences in associations by age and gender between the two Irish jurisdictions, the findings suggest potential contribution of underlying societal differences, and require further exploration. The evidence provided here will hope to contribute to the current efforts to modify fuel policy and reduce winter mortality in Ireland.
Source: BioMed Central - December 6, 2014 Category: Journals (General) Authors: Ariana ZekaStephen BrowneHelen McAvoyPatrick Goodman Source Type: research