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Total 184 results found since Jan 2013.

343 Atrial Fibrillation, Orthostatic Hypotension and Cerebral Perfusion – Data from The Irish Longitudinal Study on Ageing
ConclusionThere is evidence that frontal lobe perfusion is lower during orthostasis in individuals with AF, and that the presence of OH modifies this association.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

Northern Ireland prepares for momentous abortion, same-sex marriage changes
Campaigners who fought for decades to end Northern Ireland's same-sex marriage ban and restrictions on abortion gathered in Belfast on Monday to prepare for a momentous change to the laws on both at the stroke of midnight.
Source: Reuters: Health - October 21, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Monitoring of atrial fibrillation in primary care patients prescribed direct oral anticoagulants for stroke prevention
ConclusionsResults show that there was incomplete adherence to the 2013 EHRA prescribing guidelines with only 24% adhering to all seven guidelines, and patient follow-up was less frequent than has been suggested.
Source: Irish Journal of Medical Science - January 2, 2020 Category: General Medicine Source Type: research

Stroke consultant shortage 'hurtling towards crisis'
Some 48% of hospitals in England, Wales and Northern Ireland do not have the staff they need, figures suggest.
Source: BBC News | Health | UK Edition - January 17, 2020 Category: Consumer Health News Source Type: news

Initial experience with React 68 aspiration catheter.
CONCLUSION: The React 68 catheter is a large-bore reperfusion catheter with trackability suitable for use in direct aspiration for recanalization of emergent large vessel occlusion. PMID: 31969073 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - January 25, 2020 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Impact of atrial fibrillation on frailty and functionality in older adults
ConclusionsEHRA AF symptom severity score is positively correlated with frailty. AF is associated with worse metabolic profile and clinical features on CGA that AF might be a frailty marker. Frailty should be investigated in AF patients.
Source: Irish Journal of Medical Science - January 28, 2020 Category: General Medicine Source Type: research

Perceptions and attitudes toward risk and personal responsibility in the context of medical fitness to drive.
Conclusions: These results suggest that more needs to be done to raise awareness of the risks posed by medical and other factors that reduce driver capability and also about drivers' responsibility to ensure that they are fit to drive and thus improve road safety. PMID: 32421397 [PubMed - as supplied by publisher]
Source: Traffic Injury Prevention - May 17, 2020 Category: Accident Prevention Authors: Ryan M, Walshe J, Booth R, O'Neill DJ Tags: Traffic Inj Prev Source Type: research

Three-year clinical outcome of unprotected left main coronary artery disease patients complicated with chronic kidney disease treated by coronary artery bypass graft versus percutaneous coronary intervention
ConclusionCABG could be considered as the preferred treatment strategy compared with PCI with DES in ULMCAD patients complicated with CKD.
Source: Irish Journal of Medical Science - June 11, 2020 Category: General Medicine Source Type: research

Inclusion of medical fitness to drive in medical postgraduate training curricula.
CONCLUSION: There are notable deficits in MFTD training for specialists in Ireland and the UK. Common conditions which can significantly impair MFTD such as stroke, diabetes and alcohol use disorders are severely underrepresented and curricula should be revisited to include relevant training and guidance on MFTD for trainees. PMID: 32936112 [PubMed - as supplied by publisher]
Source: Journal of the Royal College of Physicians of Edinburgh - September 17, 2020 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

Recognizing dysphagia: implementation of an in-hospital screening protocol
ConclusionsDespite its limitations, this study demonstrates that dysphagia screening produces a significant impact on patients ’ lives, as well as healthcare professionals and resources. We hope that our results will encourage others to adopt a patient-centred multidisciplinary approach that includes a dysphagia screening protocol.
Source: Irish Journal of Medical Science - September 21, 2020 Category: General Medicine Source Type: research

Ferritin reduction is essential for cerebral ischemia-induced hippocampal neuronal death through p53/SLC7A11-mediated ferroptosis.
This study explores the influence of lentivirus infection-induced ferritin overexpression in hippocampal neuronal injury and death through simulations in August Copenhagen Irish rat models. Twenty-four-hour cerebral ischemia-reperfusion injury was induced in the rats after 90-min middle cerebral artery occlusion (MCAO). Ferritin overexpression was induced through lentivirus infection. The Morris Water Maze (MWM) test and tau hyperphosphorylation test were performed on hippocampal neurons to establish a MCAO model. The effect of ferritin overexpression on hippocampal neuronal death was evaluated using hematoxylin-eosin stai...
Source: Brain Research - December 14, 2020 Category: Neurology Authors: Chen W, Jiang L, Hu Y, Tang N, Liang N, Li XF, Chen YW, Qin H, Wu L Tags: Brain Res Source Type: research

Exploration of patient- and relative-reported outcomes of cognitive, emotional, and social function after encephalitis.
Conclusions: Individuals affected by encephalitis experience the most significant symptoms in the somatic, cognitive, and communication domains. Outcomes as assessed by relatives were notably worse than those assessed by individuals themselves in nearly all domains. PMID: 33356613 [PubMed - as supplied by publisher]
Source: Brain Injury - December 29, 2020 Category: Neurology Tags: Brain Inj Source Type: research

A Neurodisparity Index of Nationwide Access to Neurological Health Care in Northern Ireland
Nationwide disparities in managing neurological patients have rarely been reported. We compared neurological health care between the population who reside in a Health and Social Care Trust with a tertiary neuroscience center and those living in the four non-tertiary center Trusts in Northern Ireland. Using the tertiary center Trust population as reference, neurodisparity indices (NDIs) defined as the number of treated patients resident in each Trust per 100,000 residents compared to the same ratio in the tertiary center Trust for a fixed time period. NDIs were calculated for four neurological pathways—intravenous thrombo...
Source: Frontiers in Neurology - February 12, 2021 Category: Neurology Source Type: research

Assessment of BNP and BDNF results in elective endovascular cerebral aneurysm treatment
ConclusionsAfter elective endovascular cerebral aneurysm treatment, the BNP values in serum decreased significantly, and the BDNF values in serum did not change significantly.
Source: Irish Journal of Medical Science - September 29, 2021 Category: General Medicine Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news