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Total 729 results found since Jan 2013.

More Than 50 Percent Reduction in LDL Cholesterol in Patients With Target LDL & lt;70 mg/dL After a Stroke
CONCLUSIONS: In this post hoc analysis of the TST trial, targeting an LDL cholesterol of <70 mg/dL reduced the risk of primary outcome compared with 100±10 mg/dL provided LDL cholesterol reduction from baseline was superior to 50%, thereby suggesting that the magnitude of LDL cholesterol reduction was as important to consider as the target level to achieve.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT01252875; https://clinicaltrialsregister.eu; Unique identifier: EUDRACT2009-A01280-57.PMID:37376989 | DOI:10.1161/STROKEAHA.123.042621
Source: Atherosclerosis - June 28, 2023 Category: Cardiology Authors: Pierre Amarenco Philippa C Lavall ée Jong S Kim Julien Labreuche Hugo Charles Maurice Giroud Byung-Chul Lee Marie-H élène Mahagne Elena Meseguer Norbert Nighoghossian Philippe Gabriel Steg Éric Vicaut Eric Bruckert Treat Stroke to Target Investigators Source Type: research

Carotid artery stenting using a 7 French Optimo balloon guide catheter combined with a distal filter
CONCLUSIONS: The 7 F Optimo is the smallest BGC to achieve CAS using a proximal protection system. The combined use of a 7 F Optimo BGC and a distal filter is effective for navigating the BGC and distal embolic protection.PMID:37322893 | DOI:10.1177/15910199231162493
Source: Interventional Neuroradiology - June 16, 2023 Category: Radiology Authors: Kei Harada Haruto Fujimura Masahito Kajihara Kei Arakawa Source Type: research

Mechanical thrombectomy is cost-effective versus medical management alone around Europe in patients with low ASPECTS
Conclusions MT is efficient versus MM alone for patients with low ASPECTS in eight countries across Europe. Patients with a large ischemic core could be treated with MT because it is both clinically beneficial and economically sustainable.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Moreu, M., Scarica, R., Perez-Garcia, C., Rosati, S., Lopez-Frias, A., Egido, J. A., Gomez-Escalonilla, C., Simal, P., Arrazola, J., Bocquet, A.-L., Barthe, T. Tags: Open access, Ischemic stroke Source Type: research

Meeting the need for post-stroke vision care in Australia: a scoping narrative review of current practice
CONCLUSION: Further research is needed into current Australian post-stroke vision care to accurately assess whether the needs of stroke survivors are being met. Available evidence indicates that in Australia, there is a requirement for well-defined protocols for vision screening, education, management, and referral of stroke survivors.Implications for RehabilitationPost-stroke vision care in Australia is unstandardised, which may cause inequities in vision care provision to Australian stroke survivors in different regions and/or care facilities.Education and training pertaining to stroke-related vision conditions for strok...
Source: Disability and Rehabilitation - May 25, 2023 Category: Rehabilitation Authors: Shanelle Sorbello Kathryn Rose Amanda French Fiona Rowe Sonia Lau Source Type: research

When does life end? New organ donation strategy fuels debate
On a chilly holiday Monday in January 2020, a medical milestone passed largely unnoticed. In a New York City operating room, surgeons gently removed the heart from a 43-year-old man who had died and shuttled it steps away to a patient in desperate need of a new one. More than 3500 people in the United States receive a new heart each year. But this case was different—the first of its kind in the country. “It took us 6 months to prepare,” says Nader Moazami, surgical head of heart transplantation at New York University (NYU) Langone Health, where the operation took place. The run-up included oversight from an ethi...
Source: ScienceNOW - May 11, 2023 Category: Science Source Type: news

C-reactive protein and D-dimer in cerebral vein thrombosis: Relation to clinical and imaging characteristics as well as outcomes in a French cohort study
CONCLUSION: Two widely available biomarkers measured upon admission, especially hs-CRP, could help predict bad prognosis in CVST in addition to patient characteristics. These results need to be validated in other cohorts.PMID:37138790 | PMC:PMC10149398 | DOI:10.1016/j.rpth.2023.100130
Source: Thrombosis and Haemostasis - May 4, 2023 Category: Hematology Authors: Paul Billoir Virginie Siguret Elisabeth Masson Fron Ludovic Drouet Isabelle Crassard Rapha ël Marlu Marianne Barbieux-Guillot Pierre-Emmanuel Morange Emmanuelle Robinet Catherine Metzger Val érie Wolff Elisabeth Andr é-Kerneis Fr édéric Klapczynski B Source Type: research

Effect of pharmacologic anti-atherosclerotic therapy on carotid intraplaque neovascularization: a systematic review
Atherosclerotic cardiovascular (CV) disease is one of the leading causes of global mortality. It is a progressive inflammatory disease that involves lipid accumulation in the sub-intimal layer of the arterial wall, resulting in gradual plaque formation1. Plaque rupture is implicated in a large proportion of major adverse cardiovascular events (MACE), including acute coronary syndrome and ischemic stroke. The presence of intraplaque neovascularization (IPN) in large arterial plaques have been associated with an increased risk of rupture and plaque vulnerability.
Source: Journal of Clinical Lipidology - April 26, 2023 Category: Lipidology Authors: Edward Cui, Georgia Kersche, Nicholas Grubic, Marie-France H étu, Stephen C. Pang, Henrik Sillesen, Amer M. Johri Tags: Review Article Source Type: research

Poor clinical outcome despite successful basilar occlusion recanalization in the early time window: incidence and predictors
Conclusions Early successful reperfusion with EVT occurred in 80.5% of patients, and the only treatment-related factor predictive of clinical outcome was first pass mTICI 2b-3 reperfusion. Further research is warranted to identify the optimal techniques and devices associated with first pass reperfusion in the posterior circulation.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Pop, R., Finitsis, S. N., Arquizan, C., Elhorany, M., Naggara, O., Darcourt, J., Clarencon, F., Richard, S., Marnat, G., Bourcier, R., Sibon, I., Dargazanli, C., Blanc, R., Lapergue, B., Consoli, A., Eugene, F., Vannier, S., Caroff, J., Denier, C., Boulan Tags: Editor''s choice, Ischemic stroke Source Type: research

Thrombectomy in basilar artery occlusions: impact of number of passes and futile reperfusion
Conclusions We found that BAO patients had a significant relationship between the number of MT passes and both recanalization and favorable functional outcome. We further found that the benefit of recanalization in BAO patients was significant only when recanalization was achieved within three passes, encouraging at least three passes before stopping the procedure.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: de Havenon, A., Elhorany, M., Boulouis, G., Naggara, O., Darcourt, J., Clarencon, F., Richard, S., Marnat, G., Bourcier, R., Sibon, I., Arquizan, C., Dargazanli, C., Maïer, B., Seners, P., Lapergue, B., Consoli, A., Eugene, F., Vannier, S., Caroff Tags: Ischemic stroke Source Type: research

A national survey of evidence-based stroke rehabilitation intervention use in clinical practice among Canadian occupational therapists
CONCLUSION: Significant efforts should be made to increase the awareness of interventions which are supported by strong evidence through knowledge translation and implementation initiatives, particularly for those with a technological component.PMID:37005899 | DOI:10.3233/NRE-220279
Source: NeuroRehabilitation - April 3, 2023 Category: Rehabilitation Authors: Amanda McIntyre Ricardo Viana Peiwen Cao Shannon Janzen Marcus Saikaley Amber Harnett Robert Teasell Source Type: research