Effect of pharmacologic anti-atherosclerotic therapy on carotid intraplaque neovascularization: a systematic review

Atherosclerotic cardiovascular (CV) disease is one of the leading causes of global mortality. It is a progressive inflammatory disease that involves lipid accumulation in the sub-intimal layer of the arterial wall, resulting in gradual plaque formation1. Plaque rupture is implicated in a large proportion of major adverse cardiovascular events (MACE), including acute coronary syndrome and ischemic stroke. The presence of intraplaque neovascularization (IPN) in large arterial plaques have been associated with an increased risk of rupture and plaque vulnerability.
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Tags: Review Article Source Type: research