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Total 173 results found since Jan 2013.

Pregnancy-associated stroke and the recurrence of stroke and other complications in subsequent pregnancies: Population-based retrospective cohort study
CONCLUSIONS: Subsequent pregnancies of women with a history of PAS are more often complicated with hypertensive disorders of pregnancy and any diabetes during pregnancy. PAS recurrence risk is considerable.PMID:37088716 | DOI:10.1111/1471-0528.17503
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 23, 2023 Category: OBGYN Authors: Liisa Verho Minna Tikkanen Outi Äyräs Karoliina Aarnio Kirsi Rantanen Aino Korhonen Anna Richardt Hannele Laivuori Mika Gissler Petra Ij äs Source Type: research

Letter to the editor regarding 'Less is more - the finnish prehospital stroke scale prospective validation'
Dear editor, I have read the article “Less is more – The Finnish Prehospital Stroke Scale prospective validation”1 with great interest and would want to issue some clarifications, especially those concerning the M-DIRECT scale of which I am lead author.
Source: Journal of Stroke and Cerebrovascular Diseases - April 5, 2023 Category: Neurology Authors: Jorge Rodr íguez-Pardo Tags: Letter to the Editor Source Type: research

Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study
CONCLUSIONS: Infections severe enough to require hospital treatment were associated with increased risks for major cardiovascular disease events immediately after hospitalization. A small excess risk was also observed in the long-term, but residual confounding cannot be excluded.PMID:36971007 | DOI:10.1161/CIRCULATIONAHA.122.061183
Source: Circulation - March 27, 2023 Category: Cardiology Authors: Pyry N Sipil ä Joni V Lindbohm G David Batty Nelli Heikkil ä Jussi Vahtera Sakari Suominen Ari V äänänen Aki Koskinen Solja T Nyberg Seppo Meri Jaana Pentti Charlotte Warren-Gash Andrew C Hayward Mika Kivim äki Source Type: research

Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol
Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting medical chart,” says Blendermann, a real estate agent in Prior Lake, Minnesota. Yet Blendermann’s routine lab results weren’t alarming. At checkups, her low-density lipoprotein (LDL), or “bad,” cholesterol hovered around the 100 milligrams-per-...
Source: Science of Aging Knowledge Environment - March 16, 2023 Category: Geriatrics Source Type: research

Less is more - The Finnish Prehospital Stroke Scale prospective validation
The current bifurcation of the acute stroke care pathway requires prehospital separation of strokes caused by large vessel occlusion. The first four binary items of the Finnish Prehospital Stroke Scale (FPSS) identify stroke in general, while the fifth binary item alone identifies stroke due to large vessel occlusion. The straightforward design is both easy for paramedics and statistically beneficial. We implemented FPSS based Western Finland Stroke Triage Plan, including medical districts of a comprehensive stroke center and four primary stroke centers.
Source: Journal of Stroke and Cerebrovascular Diseases - February 16, 2023 Category: Neurology Authors: Jyrki Ollikainen, Pasi Jolma, Juha-Pekka Pienim äki, Pauli Vuorinen, Niku Oksala, Marko Kimpimäki, Markku Grönroos, Tuuli-Maria Haula, Heikki Janhunen, Satu-Liisa Pauniaho Source Type: research

Outcome of transcatheter atrial septal defect closure in a nationwide cohort
CONCLUSION: After TC closure of ASD, patients had a higher risk of new-onset atrial fibrillation and migraine than controls without ASD. As novel findings, we found an increased risk for ischemic heart disease, AV conduction disorders, and ventricular fibrillation/tachycardia.Key messagesEven though patients have an excellent overall prognosis after percutaneous ASD closure, the increased incidence of major comorbidities like atrial fibrillation and heart failure prompts more thorough lifelong follow-up.This study's novel findings revealed the increased risk for ischemic heart disease, AV conduction disorders, or ventricul...
Source: Annals of Medicine - February 14, 2023 Category: Internal Medicine Authors: V Muroke M Jalanko J Haukka J Hartikainen A Tahvanainen H Ukkonen K Ylitalo J Pihkala J Sinisalo Source Type: research

Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry
ConclusionAlthough the survival of LS patients with PC or BTC is better than in sporadic cancers, it is still poor and may be reflected by the relatively higher surgical resectability accounted for by the earlier age of onset. More studies on analyses of the molecular and immune profile, screening, and management of LS-associated pancreaticobiliary cancers are warranted.
Source: Frontiers in Oncology - February 1, 2023 Category: Cancer & Oncology Source Type: research

Empagliflozin cardiovascular and renal effectiveness and safety compared to dipeptidyl peptidase-4 inhibitors across 11 countries in Europe and Asia: Results from the EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study
Diabetes Metab. 2023 Jan 3:101418. doi: 10.1016/j.diabet.2022.101418. Online ahead of print.ABSTRACTBACKGROUND: Continued expansion of indications for sodium-glucose cotransporter-2 inhibitors increases importance of evaluating cardiovascular and kidney efficacy and safety of empagliflozin in patients with type 2 diabetes compared to similar therapies.METHODS: The EMPRISE Europe and Asia study is a non-interventional cohort study using data from 2014-2019 in seven European (Denmark, Finland, Germany, Norway, Spain, Sweden, United Kingdom) and four Asian (Israel, Japan, South Korea, Taiwan) countries. Patients with type 2 d...
Source: Diabetes and Metabolism - January 7, 2023 Category: Endocrinology Authors: Avraham Karasik Stefanie Lanzinger Elise Chia-Hui Tan Daisuke Yabe Dae Jung Kim Wayne H-H Sheu Cheli Melzer-Cohen Reinhard W Holl Kyoung Hwa Ha Kamlesh Khunti Francesco Zaccardi Anuradhaa Subramanian Krishnarajah Nirantharakumar Thomas Nystr öm Leo Niska Source Type: research