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Total 143 results found since Jan 2013.

CT radiation doses for COVID-19 patients vary widely
Lack of guidance for how best to use CT with COVID-19 has led to significant...Read more on AuntMinnie.comRelated Reading: SCCT launches new cardiac CT training guidelines CT lung screening scans also work for bone density CT lung screening program falls short in China PET/CT with Ga-68 tracer better for cancer patients CTA spots COVID-19 in stroke patients
Source: AuntMinnie.com Headlines - November 11, 2020 Category: Radiology Source Type: news

Network Pharmacology-Based Approach to Revealing Biological Mechanisms of Qingkailing Injection against IschemicStroke: Focusing on Blood-Brain Barrier.
Authors: Zhang S, Wang X, Cheng F, Ma C, Fan S, Xu W, Jin N, Liu S, Lv K, Wang Q Abstract Ischemic stroke is the most common type of cerebrovascular accident worldwide. It causes long-term disability and death. Qingkailing (QKL) injection is a traditional Chinese patent medicine which has been clinically applied in the treatment of ischemic stroke for nearly thirty years. In the present study, network pharmacology combined with experimentation was used to elucidate the mechanisms of QKL. ADME screening and target prediction identified 62 active compounds and 275 targets for QKL. Topological screening of the protein...
Source: Evidence-based Complementary and Alternative Medicine - September 13, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Corrigendum: A SCANO Nomogram for Individualized Prediction of the Probability of 1-Year Unfavorable Outcomes in Chinese Acute Ischemic Stroke Patients
Source: Frontiers in Neurology - August 13, 2020 Category: Neurology Source Type: research

One-Stop MR Neurovascular Vessel Wall Imaging With a 48-Channel Coil System at 3 T
Conclusion: A 48-channel coil system was developed and demonstrated superior performance for vessel wall imaging at the intracranial and cervical carotid arteries compared with a commercial 36-channel coil. Significance: The 48-channel coil system is potentially useful for clinical diagnostics, especially when attempting to diagnose ischemic stroke.
Source: IEEE Transactions on Biomedical Engineering - July 17, 2020 Category: Biomedical Engineering Source Type: research

The relationship between the platelet to leukocyte ratio and mechanical thrombectomy outcomes in acute ischemic stroke patients.
CONCLUSION: Platelet to leukocyte ratio may be use to assess the risk of functional outcome and sICH in patients with acute anterior circulation occlusion stroke undergoing endovascular treatment in real world China. PMID: 32643590 [PubMed - as supplied by publisher]
Source: Neurological Research - July 11, 2020 Category: Neurology Tags: Neurol Res Source Type: research

A SCANO Nomogram for Individualized Prediction of the Probability of 1-Year Unfavorable Outcomes in Chinese Acute Ischemic Stroke Patients
Conclusions: The SCANO nomogram is developed and validated in Chinese AIS patients to firstly predict 1-year unfavorable outcomes, which is simple and convenient for the management of stroke patients.
Source: Frontiers in Neurology - June 29, 2020 Category: Neurology Source Type: research

Coronaviruses and Central Nervous System Manifestations
SARS-CoV-2 is a highly pathogenic coronavirus that has caused an ongoing worldwide pandemic. Emerging in Wuhan, China in December 2019, the virus has spread rapidly around the world. Corona virus disease 2019 (COVID-19), which is caused by SARS-CoV-2, has resulted in significant morbidity and mortality. The most prominent symptoms of SARS-CoV-2 infection are respiratory. However, accumulating evidence highlights involvement of the central nervous system (CNS). This includes headache, anosmia, meningoencephalitis, acute ischemic stroke, and several presumably post/para-infectious syndromes and altered mental status not expl...
Source: Frontiers in Neurology - June 22, 2020 Category: Neurology Source Type: research

Unusual Symptoms of Coronavirus: What We Know So Far
While most people are familiar with the hallmark symptoms of COVID-19 by now—cough, fever, muscle aches, headaches and difficulty breathing—a new crop of medical conditions are emerging from the more than 4 million confirmed cases of the disease around the world. These include skin rashes, diarrhea, kidney abnormalities and potentially life-threatening blood clots. It’s not unusual for viruses to directly infect and affect different tissues and organs in the body, but it is a bit unusual for a primarily respiratory virus like SARS-CoV-2, which is responsible for COVID-19, to have such a wide-ranging reach...
Source: TIME: Health - May 19, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Portable 3D-Head Computed Tomography (CT) Navigation-Guided Key-Hole Microsurgery for Spontaneous Hypertensive Hemorrhages.
CONCLUSIONS</strong> As a minimally invasive technique, image-guided transcortical sulci or transsylvian approach is highly effective for immediate and complete hematoma evacuation. PMID: 31907343 [PubMed - in process]
Source: Medical Science Monitor - January 8, 2020 Category: Research Tags: Med Sci Monit Source Type: research

A Non-linear Association Between Total Small Vessel Disease Score and Hemorrhagic Transformation After Ischemic Stroke With Atrial Fibrillation and/or Rheumatic Heart Disease
Background: Previous studies have investigated the association between a single marker of cerebral small vessel disease (SVD) and hemorrhagic transformation (HT). However, the effect of the total SVD burden on HT has not been evaluated yet. We aimed to investigate the association between the total SVD score and HT in ischemic stroke patients with atrial fibrillation (AF) and/or rheumatic heart disease (RHD). Methods: Ischemic stroke patients with AF and/or RHD admitted within 7 days after onset were enrolled at two hospitals in China. The total SVD score was based on the presence of lacunes, extensive white matter hyperin...
Source: Frontiers in Neurology - July 23, 2019 Category: Neurology Source Type: research

Tick-borne Encephalitis: Stroke-like Presentation
We report a unique case of clinical symptoms and radiological findings compatible with a stroke-like inflammatory lesion in the thalamus, suggesting microangiopathy from TBEV. Our case shows that TBEV could be a possible cause of stroke-like lesions.
Source: Journal of Stroke and Cerebrovascular Diseases - June 9, 2019 Category: Neurology Authors: Andreas Eleftheriou, Fredrik Lundin, Evangelos Alexandros Petropoulos Tags: Case Report Source Type: research

Variants in matrix metalloproteinase ‐9 gene are associated with hemorrhagic transformation in acute ischemic stroke patients with atherothrombosis, small artery disease, and cardioembolic stroke
ConclusionIncidence of HT is common in acute IS in Chinese population. The mechanisms leading to HT are most likely multifactorial. Two ‐loci interactions of rs3918242 and rs3787268 inMMP ‐9 gene may confer a higher risk for HT.
Source: Brain and Behavior - May 9, 2019 Category: Neurology Authors: Xingyang Yi, Guo Sui, Qiang Zhou, Chun Wang, Jing Lin, Zhenxiao Chai, Ju Zhou Tags: ORIGINAL RESEARCH Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin. Ethics Statement This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Sex Differences in Sex Hormone Profiles and Prediction of Consciousness Recovery After Severe Traumatic Brain Injury
Conclusion: These findings indicate that TBI differentially affects the levels of sex-steroid hormones in men and women patients. Plasma levels of testosterone could be a good candidate blood marker to predict recovery from unconsciousness after sTBI for male patients. Introduction Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is increasing in incidence (1). Patients with acute severe TBI (sTBI) often develop severe disorders of consciousness, i.e., coma, minimally conscious state or vegetative state. Although many patients may regain consciousness during the 1-month post-TBI p...
Source: Frontiers in Endocrinology - April 25, 2019 Category: Endocrinology Source Type: research