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Condition: Ischemic Stroke
Countries: Australia Health

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Total 193 results found since Jan 2013.

Linking Australian Stroke Clinical Registry data with Australian government Medicare and medication dispensing claims data and the potential for bias
Aust N Z J Public Health. 2021 Apr 5. doi: 10.1111/1753-6405.13079. Online ahead of print.ABSTRACTOBJECTIVE: We aim to report the accuracy of linking data from a non-government-held clinical quality registry to national claims data and identify associated sources of systematic bias.METHODS: Patients with stroke or transient ischaemic attack admitted to hospitals participating in the Australian Stroke Clinical Registry (AuSCR) were linked with Medicare and medication dispensings through the Australian Medicare enrolment file (MEF). The proportion of registrants in the datasets was calculated and factors associated with a no...
Source: Australian and New Zealand Journal of Public Health - April 5, 2021 Category: International Medicine & Public Health Authors: Nadine E Andrew Dominique A Cadilhac Vijaya Sundararajan Amanda G Thrift Phil Anderson Natasha A Lannin Monique F Kilkenny Source Type: research

A Cohort Study of Anticholinergic Medication Burden and Incident Dementia and Stroke in Older Adults
ConclusionsHigh anticholinergic burden in initially healthy older people was associated with increased risk of incident dementia and ischemic stroke. A vascular effect may underlie this association. These findings highlight the importance of minimizing anticholinergic exposure in healthy older people.
Source: Journal of General Internal Medicine - March 22, 2021 Category: Internal Medicine Source Type: research

Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profile backed by ove...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

COVID-19 Pandemic Impact on Care for Stroke in Australia: Emerging Evidence From the Australian Stroke Clinical Registry
We present information on acute stroke care for the first wave of the COVID-19 pandemic in Australia using data from the Australian Stroke Clinical Registry (AuSCR). The first case of COVID-19 in Australia was recorded in late January 2020 and national restrictions to control the virus commenced in March. To account for seasonal effects of stroke admissions, patient-level data from the registry from January to June 2020 were compared to the same period in 2019 (historical-control) from 61 public hospitals. We compared periods using descriptive statistics and performed interrupted time series analyses. Perceptions of stroke...
Source: Frontiers in Neurology - February 26, 2021 Category: Neurology Source Type: research

Occlusive Disease and Upright Activity in Acute Ischemic Stroke
The impact of out-of-bed upright activity on outcomes in ischemic stroke patients with severe extra- and intracranial stenosis or occlusion is unknown. Using ultrasound findings from a cohort recruited to A Very Early Rehabilitation Trial (AVERT) which compared higher dose very early mobilisation (VEM) to usual care (UC), we aimed to explore the association between occlusive disease and 3-month outcomes and occlusive disease-by-mobilisation treatment interactions. Participants with ischemic stroke, with carotid and transcranial Doppler ultrasounds performed ≤1 week after admission, were included in this single centre sub...
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Lilian B. Carvalho, Brian Chambers, Karen Borschmann, Tina Kaffenberger, Leonid Churilov, Vincent Thijs, Julie Bernhardt, AVERT trial collaboration group Source Type: research

CNS Complications in Adult Patients Treated With Extracorporeal Membrane Oxygenation
Objectives: To describe the incidence and outcomes of radiologically confirmed acute CNS complications in extracorporeal membrane oxygenation patients at an Australian extracorporeal membrane oxygenation referral center and identify associated patient characteristics. Design: Retrospective cohort study. Setting: Single-center tertiary institution. Patients: Four-hundred twelve consecutive adult patients supported with extracorporeal membrane oxygenation from 2009 to 2017. Results: Fifty-five patients (13.3%) had a CNS complication confirmed by CT or MRI, including ischemic stroke (7.0%), int...
Source: Critical Care Medicine - January 16, 2021 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research

Depression, Anxiety Three Times More Likely in People with Cannabis Use Disorder
Rates of comorbid major depressive disorder and generalized anxiety disorder are three times higher in people who have cannabis use disorder, ameta-analysis in theJournal of Affective Disorders has found.Vivian N. Onaemo, Ph.D., M.P.H., M.B.B.S., of the Government of Saskatchewan Ministry of Health in Reginia, Canada, and colleagues analyzed data from eight articles from six epidemiological surveys published from January 1980 through July 2020. There were approximately 177,000 respondents among all six surveys, and the surveys were largely conducted in the United States and Australia.The odds of having major depression wer...
Source: Psychiatr News - December 18, 2020 Category: Psychiatry Tags: cannabis cannabis use disorder depression general anxiety disorder Journal of Affective Disorders meta-analysis Source Type: research

Out of sight, out of mind: long-term outcomes for people discharged home, to inpatient rehabilitation and to residential aged care after stroke.
CONCLUSIONS: Several long-term outcomes differed significantly for patients discharged to different settings after stroke. Patients discharged to IRFs reported some better outcomes than people discharge directly home despite having markers of more severe stroke. Implications for rehabilitation People with mild strokes are usually discharged directly home, people with moderate severity strokes to inpatient rehabilitation, and people with very severe strokes are usually discharged to residential aged care facilities. People discharged to inpatient rehabilitation reported fewer problems with mobility and had a reduced risk of...
Source: Disability and Rehabilitation - December 14, 2020 Category: Rehabilitation Authors: Lynch EA, Labberton AS, Kim J, Kilkenny MF, Andrew NE, Lannin NA, Grimley R, Faux SG, Cadilhac DA Tags: Disabil Rehabil Source Type: research

Screening for Fabry Disease in Young Strokes in the Australian Stroke Clinical Registry (AuSCR)
Conclusions: These findings provide logistical data for embedding a process of automated central stroke registry screening for an additional case-finding tool in FD.
Source: Frontiers in Neurology - November 24, 2020 Category: Neurology Source Type: research

414 The Diagnostic Value of Inpatient Transthoracic Echocardiography for Stroke and TIA
Australian guidelines for ischaemic stroke recommend echocardiography for select patients in whom stroke aetiology is unclear after initial investigations.1 We sought to identify whether inpatient echocardiograms for investigation of stroke/TIA aetiology were appropriately utilised according to this recommendation.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: M. Maffey, S. Nguyen, S. Wahi Source Type: research

Australian health professionals' perceptions about the management of return to driving early after stroke: a mixed methods study - Frith J, James C, Hubbard I, Warren-Forward H.
BACKGROUND: Stroke can affect a person's ability to drive a motor vehicle. In Australia, there is a 4-week restriction in driving after stroke and a 2-week restriction after transient ischemic attack. Concerns exist as to whether people discharged home fro...
Source: SafetyLit - August 17, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Australian health professionals' perceptions about the management of return to driving early after stroke: A mixed methods study.
CONCLUSIONS: Education of health professionals in RTD guidelines is recommended to improve the processes of care after stroke. PMID: 32787668 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 12, 2020 Category: Neurology Authors: Frith J, James C, Hubbard I, Warren-Forward H Tags: Top Stroke Rehabil Source Type: research

Longitudinal Stroke Recovery Associated With Dysregulation of Complement System —A Proteomics Pathway Analysis
Currently the longitudinal proteomic profile of post-ischemic stroke recovery is relatively unknown with few well-accepted biomarkers or understanding of the biological systems that underpin recovery. We aimed to characterize plasma derived biological pathways associated with recovery during the first year post event using a discovery proteomics workflow coupled with a topological pathway systems biology approach. Blood samples (n = 180, ethylenediaminetetraacetic acid plasma) were collected from a subgroup of 60 first episode stroke survivors from the Australian START study at 3 timepoints: 3–7 days (T1), 3-months (T2) ...
Source: Frontiers in Neurology - July 27, 2020 Category: Neurology Source Type: research

Population-based stroke surveillance using big data: state-wide epidemiological trends in admissions and mortality in New South Wales, Australia.
DISCUSSION: Improved prevention may have underpinned declining intracerebral haemorrhage rates while survival gains suggest that innovations in care are being successfully translated. Mortality in patients surviving the acute period is unchanged and may be increasing for subarachnoid haemorrhage warranting investment in post-discharge care and secondary prevention. PMID: 32449879 [PubMed - as supplied by publisher]
Source: Neurological Research - May 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research