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Factors associated with delay to carotid endarterectomy for acute ischaemic stroke in South Australia: A multicentre retrospective cohort study
The greatest benefits of carotid endarterectomy (CEA) accrue when performed within two weeks of acute ischaemic stroke (AIS) due to symptomatic carotid stenosis. Previous studies have identified multiple factors contributing to CEA delay.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2022 Category: Neurology Authors: Rudy Goh, Stephen Bacchi, Joshua G. Kovoor, Aashray K. Gupta, Minh-Son To, Christopher D. Ovenden, Joseph Dawson, Wilson Vallat, David Schultz, Jim Jannes, Timothy Kleinig Source Type: research

Costs of major complications in people with and without diabetes in Tasmania, Australia
ConclusionsDiabetes complications are costly, and the costs are higher in people with diabetes than without diabetes. Our results can be used to populate diabetes simulation models and will support policy analyses to reduce the burden of diabetes.PMID:36375176 | DOI:10.1071/AH22180
Source: Australian Health Review - November 14, 2022 Category: Hospital Management Authors: Ngan T T Dinh Barbara de Graaff Julie A Campbell Matthew D Jose Burgess John Timothy Saunder Alex Kitsos Nadine Wiggins Andrew J Palmer Source Type: research

Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease
CONCLUSIONS: Globally, Lp(a) is measured in a small minority of patients with ASCVD and is highest in black, younger and female patients. More than 25% of patients had levels exceeding the established threshold for increased cardiovascular risk, approximately 50 mg/dL or 125 nmol/L.PMID:36252994 | DOI:10.1136/openhrt-2022-002060
Source: Atherosclerosis - October 17, 2022 Category: Cardiology Authors: Steven E Nissen Kathy Wolski Leslie Cho Stephen J Nicholls John Kastelein Eran Leitersdorf Ulf Landmesser Michael Blaha A Michael Lincoff Ryuichi Morishita Sotirios Tsimikas Junhao Liu Brian Manning Plamen Kozlovski Anastasia Lesogor Tom Thuren Taro Shiba Source Type: research

Stroke Epidemiology and Incidence in Regional Queensland: Findings of the Regional Queensland Stroke (REQUEST) Study
CONCLUSIONS: Incidence of stroke in a regional Queensland population is similar to other regional populations and when compared with larger cities. Despite a global trend in stroke reduction, modifiable risk factors like hypertension and atrial arrhythmias continue to be over-represented in the stroke population. All-cause mortality after stroke is high especially during the initial period. This article is protected by copyright. All rights reserved.PMID:36001407 | DOI:10.1111/imj.15917
Source: Atherosclerosis - August 24, 2022 Category: Cardiology Authors: Deepak Darshan Nisal Gange Daniel Chen Anthony Bragg Source Type: research

COVID-19 Can Increase Risk of Psychiatric Disorders for Up to Two Years
The increased risk of depression and anxiety that patients experience after developing COVID-19 typically subsides within two months, according to astudy published yesterday inThe Lancet Psychiatry. However, patients may have an elevated risk for developing other psychiatric and neurological conditions, such as psychosis, brain fog, and seizures, for up to two years after their infections.“The results have important implications for patients and health services as it suggests new cases of neurological conditions linked to COVID-19 infection are likely to occur for a considerable time after the pandemic has subsided,” s...
Source: Psychiatr News - August 18, 2022 Category: Psychiatry Tags: adults anxiety brain fog children COVID-19 delta dementia depression older adults omicron psychotic disorder seizures The Lancet Psychiatry Source Type: research

Real-world effectiveness of lipid-lowering medications on outcomes after stroke: potential implications of the new-user design
Introduction: Observational studies are increasingly being used to provide evidence on the real-world effectiveness of medications for preventing vascular diseases, such as stroke. We investigated whether the real-world effectiveness of treatment with lipid-lowering medications after ischemic stroke is affected by prevalent user bias. Methods: An observational cohort study of 90-day survivors of ischemic stroke, using person-level data from the Australian Stroke Clinical Registry (2012-2016; 45 hospitals) linked to administrative (pharmaceutical, hospital, death) records. Use of, and adherence to (proportion of days covered
Source: Neuroepidemiology - July 21, 2022 Category: Epidemiology Source Type: research

A systematic review of cost-effectiveness analyses on endovascular thrombectomy in ischemic stroke patients
ConclusionsOur study reveals significant heterogeneity in previously published thrombectomy CEAs, highlighting need for better standardization in future CEAs.Key Points• All included studies concluded thrombectomy to be cost-effective, from both long- and short-term perspectives.• Only 5 out of 22 studies undertook a societal perspective, and only 1 accounted for indirect costs.• The range of value for mRS 0–2 was 0.71–0.85 quality-adjusted life year (QALY) and 0.21–0.40 QALY for mRS 3–5.
Source: European Radiology - May 20, 2022 Category: Radiology Source Type: research

Cost-effectiveness of the Victorian Stroke Telemedicine program
ConclusionThe VST program was likely to be cost saving or cost-effective. Our findings provide confidence in supporting wider implementation of telemedicine for acute stroke care in Australia.PMID:35589669 | DOI:10.1071/AH21377
Source: Australian Health Review - May 19, 2022 Category: Hospital Management Authors: Joosup Kim Elise Tan Lan Gao Marj Moodie Helen M Dewey Kathleen L Bagot Nancy Pompeani Lauren Sheppard Christopher F Bladin Dominique A Cadilhac Source Type: research

Time to antithrombotic therapy after transient ischaemic attack and ischaemic stroke
Med J Aust. 2022 May 11. doi: 10.5694/mja2.51532. Online ahead of print.NO ABSTRACTPMID:35546263 | DOI:10.5694/mja2.51532
Source: Medical Journal of Australia - May 13, 2022 Category: General Medicine Authors: Thanh G Phan Benjamin Clissold Henry Ma Source Type: research

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