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Total 551 results found since Jan 2013.

Understanding the impact of psychosocial working conditions on workers ’ health: we have come a long way, but are we there yet?
This issue of the journal includes a meta-review, ie, a systematic review of systematic reviews, summarizing the published evidence on the associations between exposure to adverse psychosocial working conditions and risk of developing diseases or disorders during the past 20 years (1). Although the authors allowed inclusion of reviews reporting results from cross-sectional studies, the majority of the included reviews were restricted to prospective cohort studies – the gold standard method in psychosocial occupational epidemiology. We commend the authors for their succinct summary of the current knowledge on the topic, e...
Source: Scandinavian Journal of Work, Environment and Health - September 3, 2021 Category: Occupational Health Tags: Editorial Source Type: research

Circulating TNFrII levels predict incidence of ischemic heart disease and total mortality, independently of intima media thickness and pulse wave velocity in male with type 2 diabetes
AbstractNew and clinically useful markers of cardiovascular risk are of great importance in patients with type 2 diabetes since cardiovascular disease is a major cause of death in these patients. We analyzed inflammatory markers and other risk factors for heart disease in 761 patients who participated in the CARDIPP-study, Cardiovascular Risk factors in Patients with Diabetes —a Prospective study in Primary care. All participants had type 2 diabetes and were 55–66 years old at recruitment during the years 2005–2008. Patients were followed for incidence of stroke, myocardial infarction, or death from cardiovascular d...
Source: Heart and Vessels - August 21, 2021 Category: Cardiology Source Type: research

A Novel Mutation in COL4A1 Gene in a Chinese Family with Pontine Autosomal Dominant Microangiopathy and Leukoencephalopathy
We report a novel collagen type IV alpha 1 (COL4A1) gene mutation in a Chinese family with PADMAL. The index case was followed up for 6  years. Neuroimaging, whole-exome sequencing, skin biopsy, and pedigree analysis were performed. She initially presented with minor head injury at age 38. MRI brain showed chronic lacunar infarcts in the pons, left thalamus, and right centrum semiovale. Extensive workup was unremarkable except for a patent foramen ovale (PFO). Despite anticoagulation, PFO closure, and antiplatelet therapy, the patient had recurrent lacunar infarcts in the pons and deep white matter, as well as subcortical...
Source: Translational Stroke Research - August 20, 2021 Category: Neurology Source Type: research

Global research trends in COVID-19 with MRI and PET/CT: a scoping review with bibliometric and network analyses
ConclusionCOVID-19 pandemic is still spreading worldwide, and the knowledge about its different facets continues advancing. MRI and PET/CT are being used in more than 50% of the selected studies; research trends span seven categories, no only the diagnostic but others like socio-economic impact and pathogenesis Developed countries had an advantage by having hospitals with more resources, including MRI and PET/CT facilities in the same institution to supplement basic assessment in patients with COVID-19.
Source: Clinical and Translational Imaging - August 14, 2021 Category: Radiology Source Type: research

Loss of height predicts total and cardiovascular mortality: a cohort study of northern European women
Conclusion Height loss is a marker for excess mortality in northern European women. Specifically the hazard of CVD mortality is increased in women with height loss during middle age, and the results suggest that the strongest cause-specific endpoint may be stroke mortality. The present findings suggest attention to height loss in early and mid-adulthood to identify women at high risk of CVD, and that regular physical activity may prevent early onset height loss.
Source: BMJ Open - August 9, 2021 Category: General Medicine Authors: Klingberg, S., Mehlig, K., Dangol, R., Björkelund, C., Heitmann, B. L., Lissner, L. Tags: Open access, Press releases, Epidemiology Source Type: research

Severe chickenpox disease and seroprevalence in Sweden – implications for general vaccination
Chickenpox is the clinical manifestation of primary infection with varicella zoster virus (VZV) and a mild disease in the vast majority of cases. However, complications occur, primarily bacterial infections of vesicles, sometimes with deeper infection and sepsis, as well as neurological complications; e.g. encephalitis, meningitis, or classically acute cerebellitis with ataxia. Rare complications such as pneumonitis, hepatitis and haemorrhagic complications may occur (Gershon et al., 2018). There is even an increased risk of stroke in the time period 6 months after a chickenpox episode (Thomas et al., 2014).
Source: International Journal of Infectious Diseases - August 8, 2021 Category: Infectious Diseases Authors: K Widgren, L Persson Berg, A M örner, L Lindquist, A Tegnell, J Giesecke, M Studahl Source Type: research

Increased risk of heart attack, stroke in first two weeks following Covid: Lancet study
"We found a three-fold increased risk of acute myocardial infarction and stroke in the first two weeks following COVID-19," said Osvaldo Fonseca Rodriguez from Umea University in Sweden, and co-first author of the study.
Source: The Economic Times - August 3, 2021 Category: Consumer Health News Source Type: news

Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study, The Lancet
The self-controlled case series (n=86,742) and matched cohort study (additional 348,481 control individuals) found Covid-19 was associated with increased risk of acute MI, highest during the first week, suggesting they represent a part of the clinical picture of Covid-19.
Source: Current Awareness Service for Health (CASH) - August 2, 2021 Category: Consumer Health News Source Type: news

Cardiovascular Risk in Users of Mirabegron Compared with Users of Antimuscarinic Treatments for Overactive Bladder: Findings from a Non-Interventional, Multinational, Cohort Study
ConclusionsThis large, multinational study found no higher risk of MACE, AMI, stroke, CV mortality or all-cause mortality among users of mirabegron relative to users of antimuscarinics.
Source: Drug Safety - August 1, 2021 Category: Drugs & Pharmacology Source Type: research

Cardiovascular Event Rates After Myocardial Infarction or Ischaemic Stroke in Patients with Additional Risk Factors: A Retrospective Population-Based Cohort Study
ConclusionDespite previous use of moderate- or high-intensity statins, patients with a history of MI or IS, and additional risk factors remain at very high cardiovascular risk.
Source: Advances in Therapy - July 26, 2021 Category: Drugs & Pharmacology Source Type: research

Blood pressure levels and risk of haemorrhagic stroke in patients with atrial fibrillation and oral anticoagulants: results from The Swedish Primary Care Cardiovascular Database of Skaraborg
Conclusion: In this cohort of primary care patients with hypertension and atrial fibrillation, we found that baseline SBP in the 145–180 mmHg range, prior to initiation of OAC, was associated with a more than doubled risk of haemorrhagic stroke, as compared with an SBP of 130 mmHg. This suggests that lowering SBP to below 145 mmHg, prior to initiation of OAC, may decrease the risk of haemorrhagic stroke in patients with hypertension and atrial fibrillation.
Source: Journal of Hypertension - July 9, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Cardiovascular Risk in Users of Mirabegron Compared with Users of Antimuscarinic Treatments for Overactive Bladder: Findings from a Non-Interventional, Multinational, Cohort Study
ConclusionsThis large, multinational study found no higher risk of MACE, AMI, stroke, CV mortality or all-cause mortality among users of mirabegron relative to users of antimuscarinics.
Source: Drug Safety - July 8, 2021 Category: Drugs & Pharmacology Source Type: research

A third of dying patients do not have end-of-life discussions with a physician: A nationwide registry study
Palliat Support Care. 2021 Jun 23:1-6. doi: 10.1017/S1478951521000973. Online ahead of print.ABSTRACTOBJECTIVE: The aim of the study was to explore the proportion of adult patients and next-of-kin who had end-of-life (EOL) discussions and associated factors.METHOD: A retrospective nationwide registry study was reported with data from the Swedish Register of Palliative Care. All patients in Sweden in hospitals, nursing homes, own homes, community, and palliative care units during 2015-2017 and their next-of-kin were included. Data were reported to the register by healthcare staff, based on diseased patients' records regardi...
Source: Palliative and Supportive Care - June 23, 2021 Category: Palliative Care Authors: Christina Melin-Johansson Josefin Sveen Malin L övgren Camilla Udo Source Type: research

Mom ' s Blood Pressure in Pregnancy Could Affect Child ' s Stroke Risk Decades Later
TUESDAY, June 1, 2021 -- Expectant mothers ' high blood pressure heightens kids ' risk of stroke later in life, a Swedish study finds. " Our findings indicate that hypertensive disorders during pregnancy are associated with increased risks of stroke...
Source: Drugs.com - Daily MedNews - June 1, 2021 Category: General Medicine Source Type: news

Country of birth and mortality risk in hypertension with and without diabetes: the Swedish primary care cardiovascular database
Conclusion: In Sweden, hypertensive immigrants (with the exception for Finnish-born) with and without diabetes have a mortality advantage, as compared to Swedish-born.
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research