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Condition: Thrombosis
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Total 840 results found since Jan 2013.

Carotid Web and Ischemic Stroke: A Primer for Nursing
CONCLUSION: With multiple options and the uncertainty of which are best, patients can be lost to follow-up because of confusion and stress. Involving neuroscience nurses in the education process of these patients may help facilitate understanding of this disease phenomenon and increase patient understanding and compliance.
Source: Journal of Neuroscience Nursing - May 18, 2021 Category: Neuroscience Tags: Clinical Nursing Focus Source Type: research

Evaluation of a multicomponent intervention to shorten thrombolytic door-to-needle time in stroke patients in China (MISSION): A cluster-randomized controlled trial
ConclusionsThe teleconference-delivered PEITEM intervention resulted in a moderate but clinically relevant shorter DNT and better functional outcome in AIS patients receiving IVT. Trial registrationClinicaltrials.gov NCT03317639.
Source: PLoS Medicine - July 5, 2022 Category: Internal Medicine Authors: Wansi Zhong Source Type: research

Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events (P6.241)
Conclusion- Patient’s knowledge about OAT was suboptimal. The findings support the need for educational interventions to improve the knowledge regarding oral anticoagulation therapy, and thereby achieve an appropriate and safe secondary prevention of stroke.Disclosure: Dr. Bhatia has nothing to disclose. Dr. Alphonsa has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bhatia, R., Alphonsa, A., Sharma, K., Sharma, G. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Percutaneous Closure of the Left Atrial Appendage for Stroke Prevention in Atrial Fibrillation: An Alternative to Lifelong Anticoagulation?
Atrial fibrillation is an important risk factor for thromboembolic stroke and it significantly increases the risk of stroke. The left atrial appendage (LAA) is the most common site of thrombus formation in nonvalvular atrial fibrillation, and the recent applications of percutaneous LAA closure devices offer a promising alternative for patients who are unable to tolerate lifelong anticoagulation. Critical care nurses who understand the procedures and are familiar with the various devices used for LAA closure will be well prepared to provide optimum care and appropriate education for these patients.
Source: Critical Care Nursing Quarterly - September 11, 2015 Category: Nursing Tags: Original Articles Source Type: research

Hemostasis Biomarkers and Risk of Sepsis: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort
ConclusionBaseline fibrinogen, factor IX, and factor XI are associated with future episodes of sepsis. Hemostasis biomarkers may provide targets for sepsis mitigation or prevention.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 30, 2016 Category: Hematology Authors: Justin Xavier Moore, Neil A. Zakai, Mythreyi Mahalingam, Russell L. Griffin, Marguerite R. Irvin, Monika M. Safford, John W. Baddley, Henry E Wang Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research

Venous thromboembolism and stroke in pregnancy.
Authors: McLean K, Cushman M Abstract Pregnancy and the postpartum period substantially increase the risk for thrombotic events. Although the absolute risk for thrombosis is low, these events comprise a significant portion of maternal morbidity and mortality. The vast majority of such events are venous, although the risk for ischemic stroke also appears to be increased in pregnancy. This review will explore the overlapping and unique risk factors for venous and arterial thrombosis in pregnancy. Diagnosis and prevention will be discussed, and treatment will be briefly touched on. The benefit of using a multidiscipli...
Source: Hematology ASH Education Program - December 4, 2016 Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research

Survey of confidence in use of stroke and bleeding risk calculators, knowledge of anticoagulants, and comfort with prescription of anticoagulation in challenging scenarios: SUPPORT-AF II study
AbstractHalf of patients with atrial fibrillation (AF) and elevated stroke risk do not receive anticoagulation (AC). Explanations for undertreatment may relate to provider lack of confidence with or knowledge of the CHA2DS2-VASc stroke calculator, unfamiliarity with direct oral anticoagulants (DOACs), or uncertainty about use of AC after bleeding events or other challenging patient scenarios. We surveyed cardiology and primary care providers (PCPs) within a large healthcare system to investigate prescriber knowledge, confidence, and comfort prescribing AC for AF in challenging scenarios. Of 112 providers invited, 70 (63%) ...
Source: Journal of Thrombosis and Thrombolysis - September 10, 2019 Category: Hematology Source Type: research

Stent-retriever Therapy Improves the Rate of Functional Independence for Acute Ischemic Patients
NEW YORK (Reuters Health) – Stent-retriever therapy for the treatment of acute ischemic stroke improves the rate of functional independence at 90 days, according to a systematic review and meta-analysis. Stent retrievers are deployed in an occluded vessel, temporarily expanded into the body of a thrombus, and then retracted along with the thrombus. Dr. Mark... [Read More]
Source: The Hospitalist - February 9, 2016 Category: Hospital Management Authors: Will Boggs MD Tags: Clinical Education Hospitalist Innovation acute ischemic patients stroke treatment Source Type: research

Safety of OnabotulinumtoxinA Treatment With Concomitant Antithrombotic Therapy in Patients With Post-stroke Spasticity: A Pooled Analysis of Randomized, Double-Blind Studies (S56.008)
Conclusions:There is no apparent increased risk of bleeding complications in patients on antithrombotics following IM onabotA treatment; nonetheless, careful observation of the injection site and patient education of the potential for bleeding complications remain warranted.Study Supported by: Allergan plc, Dublin, IrelandDisclosure: Dr. Dimitrova has received personal compensation for activities with Allergan as an employee. Dr. Dimitrova holds stock and/or stock options in Allergan. Dr. James has received personal compensation for activities with Allergan and Chase Pharmaceuticals as an employee. Dr. Liu has received per...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Dimitrova, R., James, L., Liu, C., Orejudos, A., Yushmanova, I., Brin, M. Tags: Movement Disorders: Huntington ' s Disease and Drug-Induced Dyskinesias Source Type: research

Factors delaying intravenous thrombolytic therapy in acute ischaemic stroke: a systematic review of the literature
ConclusionFurther integrated processes are required to maximise patient benefit from thrombolysis. Expansion of community education to incorporate less common symptoms and provision of alert pagers for patients may provide further reduction in thrombolysis times.
Source: Journal of Neurology - March 20, 2020 Category: Neurology Source Type: research

A case of “smoldering” immune‐mediated thrombotic thrombocytopenic purpura manifesting as recurrent cardioembolic stroke
We report an atypical manifestation of immune-mediated thrombotic thrombocytopenic purpura (TTP) that we hypothesize represents a longstanding, or “smoldering,” process. As typified by this case, the prompt recognition and treatment for immune-mediated TTP are often confounded by clinical comorbidities. Thus, TTP should be considered in cases of unremitting thrombocytopenia of unknown origin in patients with stroke or other thrombosis. AbstractPrompt recognition and treatment for thrombotic thrombocytopenic purpura (TTP) are critical to prevent the irreversible manifestations of this rare and quickly fatal hematologic ...
Source: Clinical Case Reports - October 12, 2021 Category: General Medicine Authors: Mark E. Pepin, Eyad Saca, Soo Y. Kwon, Jori May Tags: CASE REPORT Source Type: research

The influence of unexpected early termination of intravenous rt-PA treatment on clinical outcome in acute ischemic stroke patients
ConclusionSubjective wishes of family members and persistently elevated blood pressure may be the main causes of early termination of thrombolysis, and the 3-month prognosis of patients could be adversely affected by early termination of thrombolytic therapy and cumulative dosage of rt-PA. Certain measures, such as popularizing thrombolytic health education and optimizing blood pressure management before and during thrombolysis, may be helpful for the normal operation of intravenous thrombolysis.
Source: Acta Neurologica Belgica - August 2, 2022 Category: Neurology Source Type: research

Lipoprotein(a) and risk of cognitive impairment in Black and White Americans: the Reasons for Geographic and Racial Differences in Stroke cohort
CONCLUSION: Higher Lp(a) was associated with increased risk of cognitive impairment in Black but not White individuals. Future studies should evaluate the biological and social mechanisms through which race and Lp(a) interact to increase risk of cognitive impairment.PMID:37694266 | PMC:PMC10491800 | DOI:10.1016/j.rpth.2023.102170
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Miguel Arce Renter ía Leslie A McClure Peter W Callas Vanessa M LaBode-Richman Danielle S Kroll Jennifer J Manly Neil A Zakai Frederick Unverzagt Mary Cushman Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research