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Developments in distinguishing secondary vascular headache from primary headache disorders in clinical practice
Expert Rev Neurother. 2021 Oct 4:1-13. doi: 10.1080/14737175.2021.1984882. Online ahead of print.ABSTRACTINTRODUCTION: Vascular headaches are secondary headache disorders with potentially devastating consequences if missed. Clinicians often struggle to distinguish these from primary headache disorders whereby there is no underlying structural pathology. Here, the authors describe the advancement in our understanding of vascular headache disorders, their clinical presentation and the developments in neuroimaging that facilitate diagnosis.AREAS COVERED: Here the authors discuss the definition of primary and secondary headach...
Source: Expert Review of Neurotherapeutics - September 23, 2021 Category: Neurology Authors: Sophie Dorsey Fayyaz Ahmed Source Type: research

Elevated Aortic Pulse Wave Velocity Relates to Longitudinal Gray and White Matter Changes
CONCLUSIONS: In older adults, higher baseline aortic PWV related to greater decrease in gray matter volume and greater increase in WMHs over time. Because of unmet cerebral metabolic demands and microvascular remodeling, arterial stiffening may preferentially affect certain highly active brain regions like the temporal lobes. These same regions are affected early in the course of Alzheimer disease.PMID:34706559 | DOI:10.1161/ATVBAHA.121.316477
Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 28, 2021 Category: Cardiology Authors: Corey W Bown Omair A Khan Elizabeth E Moore Dandan Liu Kimberly R Pechman Francis E Cambronero James G Terry Sangeeta Nair L Taylor Davis Katherine A Gifford Bennett A Landman Timothy J Hohman John Jeffrey Carr Angela L Jefferson Source Type: research

Developments in distinguishing secondary vascular headache from primary headache disorders in clinical practice
Expert Rev Neurother. 2021 Oct 4:1-13. doi: 10.1080/14737175.2021.1984882. Online ahead of print.ABSTRACTINTRODUCTION: Vascular headaches are secondary headache disorders with potentially devastating consequences if missed. Clinicians often struggle to distinguish these from primary headache disorders whereby there is no underlying structural pathology. Here, the authors describe the advancement in our understanding of vascular headache disorders, their clinical presentation and the developments in neuroimaging that facilitate diagnosis.AREAS COVERED: Here the authors discuss the definition of primary and secondary headach...
Source: Expert Review of Neurotherapeutics - September 23, 2021 Category: Neurology Authors: Sophie Dorsey Fayyaz Ahmed Source Type: research

Elevated Aortic Pulse Wave Velocity Relates to Longitudinal Gray and White Matter Changes
CONCLUSIONS: In older adults, higher baseline aortic PWV related to greater decrease in gray matter volume and greater increase in WMHs over time. Because of unmet cerebral metabolic demands and microvascular remodeling, arterial stiffening may preferentially affect certain highly active brain regions like the temporal lobes. These same regions are affected early in the course of Alzheimer disease.PMID:34706559 | DOI:10.1161/ATVBAHA.121.316477
Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 28, 2021 Category: Cardiology Authors: Corey W Bown Omair A Khan Elizabeth E Moore Dandan Liu Kimberly R Pechman Francis E Cambronero James G Terry Sangeeta Nair L Taylor Davis Katherine A Gifford Bennett A Landman Timothy J Hohman John Jeffrey Carr Angela L Jefferson Source Type: research

Developments in distinguishing secondary vascular headache from primary headache disorders in clinical practice
Expert Rev Neurother. 2021 Oct 4:1-13. doi: 10.1080/14737175.2021.1984882. Online ahead of print.ABSTRACTINTRODUCTION: Vascular headaches are secondary headache disorders with potentially devastating consequences if missed. Clinicians often struggle to distinguish these from primary headache disorders whereby there is no underlying structural pathology. Here, the authors describe the advancement in our understanding of vascular headache disorders, their clinical presentation and the developments in neuroimaging that facilitate diagnosis.AREAS COVERED: Here the authors discuss the definition of primary and secondary headach...
Source: Expert Review of Neurotherapeutics - September 23, 2021 Category: Neurology Authors: Sophie Dorsey Fayyaz Ahmed Source Type: research

Elevated Aortic Pulse Wave Velocity Relates to Longitudinal Gray and White Matter Changes
CONCLUSIONS: In older adults, higher baseline aortic PWV related to greater decrease in gray matter volume and greater increase in WMHs over time. Because of unmet cerebral metabolic demands and microvascular remodeling, arterial stiffening may preferentially affect certain highly active brain regions like the temporal lobes. These same regions are affected early in the course of Alzheimer disease.PMID:34706559 | DOI:10.1161/ATVBAHA.121.316477
Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 28, 2021 Category: Cardiology Authors: Corey W Bown Omair A Khan Elizabeth E Moore Dandan Liu Kimberly R Pechman Francis E Cambronero James G Terry Sangeeta Nair L Taylor Davis Katherine A Gifford Bennett A Landman Timothy J Hohman John Jeffrey Carr Angela L Jefferson Source Type: research

Developments in distinguishing secondary vascular headache from primary headache disorders in clinical practice
Expert Rev Neurother. 2021 Oct 4:1-13. doi: 10.1080/14737175.2021.1984882. Online ahead of print.ABSTRACTINTRODUCTION: Vascular headaches are secondary headache disorders with potentially devastating consequences if missed. Clinicians often struggle to distinguish these from primary headache disorders whereby there is no underlying structural pathology. Here, the authors describe the advancement in our understanding of vascular headache disorders, their clinical presentation and the developments in neuroimaging that facilitate diagnosis.AREAS COVERED: Here the authors discuss the definition of primary and secondary headach...
Source: Expert Review of Neurotherapeutics - September 23, 2021 Category: Neurology Authors: Sophie Dorsey Fayyaz Ahmed Source Type: research

Elevated Aortic Pulse Wave Velocity Relates to Longitudinal Gray and White Matter Changes
CONCLUSIONS: In older adults, higher baseline aortic PWV related to greater decrease in gray matter volume and greater increase in WMHs over time. Because of unmet cerebral metabolic demands and microvascular remodeling, arterial stiffening may preferentially affect certain highly active brain regions like the temporal lobes. These same regions are affected early in the course of Alzheimer disease.PMID:34706559 | DOI:10.1161/ATVBAHA.121.316477
Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 28, 2021 Category: Cardiology Authors: Corey W Bown Omair A Khan Elizabeth E Moore Dandan Liu Kimberly R Pechman Francis E Cambronero James G Terry Sangeeta Nair L Taylor Davis Katherine A Gifford Bennett A Landman Timothy J Hohman John Jeffrey Carr Angela L Jefferson Source Type: research