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Specialty: Neurology
Condition: Patent Foramen Ovale

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Total 305 results found since Jan 2013.

Thrombosis at the Site of Pulmonary Venous Anastomosis Following Lung Transplantation Presenting with Multiple, Bilateral, Supra- and Infra-Tentorial Ischemic Strokes in the Setting of a Known Patent Foramen Ovale (P4.355)
CONCLUSIONS: PFO-related stroke risk over time remains a controversial matter and so does its prevention by closure, as there is no current evidence-based data to justify this procedure except on anecdotal basis. LT patients may represent a subset population who could benefit from pre-operative PFO screening and closure, especially if they have a history of prior strokes.Disclosure: Dr. Yeung has nothing to disclose. Dr. Bakhos has nothing to disclose. Dr. Biller has received personal compensation in an editorial capacity for the Journal of Stroke and Cerebrovascular Diseases, Frontier in Neurology and Up-To-Date.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yeung, S., Bakhos, M., Biller, J. Tags: Cerebrovascular Case Reports Source Type: research

Stroke Due to Air Embolism Related to Laser Ablation of Accessory Vein (P4.357)
Conclusions: Air embolism leading to devastating stroke may occur few hours after laser treatment of varicose veins. Chest symptoms associated with the procedure should raise the possibility of air embolism. Immediate therapeutic measures like 100[percnt] oxygen, hyperbaric oxygen chamber and/or hypothermia should be considered to prevent neurologic complications.Disclosure: Dr. Kale has nothing to disclose. Dr. Javed has nothing to disclose. Dr. Pednekar has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Resor has nothing to disclose. Dr. Tenner has nothing to disclose. Dr. Ahluwalia-Singh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kale, P., Javed, B., Pednekar, N., Sahni, R., Resor, L., Tenner, M., Ahluwalia-Singh, B. Tags: Cerebrovascular Case Reports Source Type: research

Transcranial Doppler versus transthoracic echocardiography for the detection of patent foramen ovale in patients with cryptogenic cerebral ischemia: A systematic review and diagnostic test accuracy meta‐analysis
This article is protected by copyright. All rights reserved.
Source: Annals of Neurology - February 2, 2016 Category: Neurology Authors: Aristeidis H. Katsanos, Theodora Psaltopoulou, Theodoros N. Sergentanis, Alexandra Frogoudaki, Agathi‐Rosa Vrettou, Ignatios Ikonomidis, Ioannis Paraskevaidis, John Parissis, Chrysa Bogiatzi, Christina Zompola, John Ellul, Nikolaos Triantafyllou, Konsta Tags: Research Article Source Type: research

Predictors for atrial fibrillation detection after cryptogenic stroke: Results from CRYSTAL AF
Conclusion: Increasing age and a prolonged PR interval at enrollment were independently associated with an increased AF incidence in CS patients. However, they offered only moderate predictive ability in determining which CS patients had AF detected by the ICM.
Source: Neurology - January 18, 2016 Category: Neurology Authors: Thijs, V. N., Brachmann, J., Morillo, C. A., Passman, R. S., Sanna, T., Bernstein, R. A., Diener, H.-C., Di Lazzaro, V., Rymer, M. M., Hogge, L., Rogers, T. B., Ziegler, P. D., Assar, M. D. Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), Risk factors in epidemiology ARTICLE Source Type: research

The value of transesophageal echocardiography in the investigation and management of cryptogenic cerebral ischemia: a single-center experience
Abstract The diagnostic utility of transesophageal echocardiography (TEE) has often been challenged in patients with cryptogenic stroke (CS). We estimated the prevalence of different findings on TEE examination of CS patients, their impact on secondary stroke prevention and the presence of potential age or gender disparities. We reviewed all TEE examinations that were performed in a single echocardiography laboratory during a 7-year-old period to identify CS patients that underwent investigation with TEE. Of the 518 total TEE examinations, we identified 88 CS patients. TEE revealed abnormal findings in 69.3 % of ...
Source: Neurological Sciences - December 24, 2015 Category: Neurology Source Type: research

Migraine makes the stroke grow faster?
Long associated with increased incidence of stroke,1,2 migraine has been linked with mechanisms involving the vasculature (vasospasm, arterial dissection, endothelial dysfunction, venous thrombosis), heart (patent foramen ovale), and blood (hypercoagulability).3 Since cerebral ischemia can induce cortical spreading depression, the physiologic process underlying aura, migraine with aura may theoretically represent a TIA equivalent in a subset of people. In addition to the heightened occurrence of stroke in migraineurs, a growing body of evidence suggests more dire consequences when stroke occurs, with experiments in mice wi...
Source: Neurology - November 30, 2015 Category: Neurology Authors: Tietjen, G. E., Sacco, S. Tags: Migraine, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

The diagnostic yield of transesophageal echocardiography in patients with cryptogenic cerebral ischaemia: a meta‐analysis
ConclusionRoutine TEE in patients with cryptogenic IS/TIA commonly identifies abnormal findings. However, the prevalence of cardiac conditions considered to be causally associated with cerebral ischaemia (intracardiac thrombi and tumors) is low.
Source: European Journal of Neurology - November 20, 2015 Category: Neurology Authors: A. H. Katsanos, S. Giannopoulos, A. Frogoudaki, A.‐R. Vrettou, I. Ikonomidis, I. Paraskevaidis, C. Zompola, K. Vadikolias, E. Boviatsis, J. Parissis, K. Voumvourakis, A. P. Kyritsis, G. Tsivgoulis Tags: Original Article Source Type: research

Impact of BNP on cryptogenic stroke without potential embolic sources on transesophageal echocardiography
This study sought to analyze the clinical signs of cryptogenic stroke (CS) without such embolic etiologies and to examine the association between CS and brain natriuretic peptide (BNP), which is currently unknown.
Source: Journal of the Neurological Sciences - November 11, 2015 Category: Neurology Authors: Yuji Ueno, Ryota Tanaka, Kazuo Yamashiro, Yoshiaki Shimada, Takuma Kuroki, Kenichiro Hira, Takao Urabe, Nobutaka Hattori Source Type: research

Differential Lesion Patterns on T2WI and FLAIR Sequences in Cryptogenic Stroke Patients With Patent Foramen Ovale
Objectives: The purpose of this study was to determine lesion patterns and stroke mechanisms in cryptogenic ischemic stroke patients with patent foramen ovale (PFO) on T2-weighted magnetic resonance imaging and fluid-attenuated inversion recovery sequences combined. Participants and Methods: Twenty-nine patients with cryptogenic ischemic stroke and an isolated PFO (CS-PFO+ group) compared with 51 cryptogenic stroke patients without PFO (CS-PFO− group) were evaluated and the characteristics of their lesion patterns on T2-weighted and fluid-attenuated inversion recovery sequences combined were investigated. We compared the...
Source: The Neurologist - November 1, 2015 Category: Neurology Tags: Original Article Source Type: research

Potential new uses of non-vitamin K antagonist oral anticoagulants to treat and prevent stroke
Conclusion: There may be a role for NOACs in stroke prevention and treatment beyond atrial fibrillation. Randomized controlled trials are needed to compare NOACs to current stroke prevention and treatment strategies in certain subgroups of patients with cerebrovascular disease.
Source: Neurology - September 21, 2015 Category: Neurology Authors: Yaghi, S., Kamel, H., Elkind, M. S. V. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Infarction, Cerebral venous thrombosis VIEWS & amp;amp; REVIEWS Source Type: research

Stroke in the Young: Patent Foramen Ovale and Pregnancy Illustrative Teaching Cases
Source: Stroke - July 27, 2015 Category: Neurology Authors: Miller, B. R., Strbian, D., Sundararajan, S. Tags: Anticoagulants, Antiplatelets, Other Stroke Treatment - Surgical Illustrative Teaching Cases Source Type: research

Diagnostic Yield of Venous Thrombosis and Pulmonary Embolism by Combined CT Venography and Pulmonary Angiography in Patients with Cryptogenic Stroke and Patent Foramen Ovale
Background: Paradoxical embolism via a patent foramen ovale (PFO) has been suggested as a potential stroke mechanism. Combined CT venography and pulmonary angiography (CVPA) is a simple, validated and accurate technique to diagnose deep venous thrombosis (DVT) or pulmonary embolism (PE). We sought to assess the prevalence of DVT or PE among patients with PFO and cryptogenic stroke (CS) by CVPA. Methods: Patients were identified retrospectively from a clinical registry of consecutive patients with stroke admitted to our Stroke Unit. The following criteria were required for inclusion in this study: CS, PFO identified by tran...
Source: European Neurology - July 25, 2015 Category: Neurology Source Type: research

Ischemic Stroke Patients with Active Malignancy or Extracardiac Shunts Are More Likely to Have a Right-to-Left Shunt Found by TCD Than Echocardiogram
Abstract Although the association between patent foramen ovale and ischemic stroke is controversial, the evaluation for a right-to-left shunt remains part of the standard workup for cryptogenic stroke. Transthoracic and transesophageal echocardiogram (TTE and TEE) are the screening test and gold standard to evaluate for right-to-left shunt, respectively. Studies comparing TTE or TEE to transcranial Doppler (TCD) have shown that 15–25 % of patients test positive for right-to-left shunt on TCD but are negative on TTE or TEE. We sought to further explore this phenomenon in patients with recent ischemic stroke. Bet...
Source: Translational Stroke Research - July 25, 2015 Category: Neurology Source Type: research

The RoPE Score and Right-to-Left Shunt Severity by Transcranial Doppler in the CODICIA Study
Conclusions: For patients with CS, severity of RLSh by c-TCD is positively correlated with the RoPE score, indicating that this technique for shunt grading identifies patients more likely to have pathogenic rather than incidental PFOs. c-TCD is also more sensitive in detecting RLSh than TEE. These findings suggest an important role for c-TCD in the evaluation of PFO in the setting of CS.Cerebrovasc Dis 2015;40:52-58
Source: Cerebrovascular Diseases - July 11, 2015 Category: Neurology Source Type: research

Orthodeoxia-platypnea syndrome and stroke: Overlapping pathophysiology
Orthodeoxia-platypnea syndrome (OPS) is a rare cause of dyspnea and hypoxemia induced by upright positioning due to orthostatic conditions [1]. Right-to-left interatrial shunt due to an atrial septal defect or patent foramen ovale (PFO) is the most common cause of this syndrome [2]. Although PFO has been implicated as a potential cause of paradoxical embolism and cerebral embolism in cryptogenic stroke [3], OPS due to PFO has rarely been described presenting as stroke [2,4,5].
Source: Journal of the Neurological Sciences - June 24, 2015 Category: Neurology Authors: Célia Machado, Ricardo Pereira, José Amorim, Carlos Galvão, João Pinho, Carla Ferreira, João Rocha Tags: Letter to the Editor Source Type: research