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Specialty: Neurology
Condition: Patent Foramen Ovale

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Total 305 results found since Jan 2013.

Guidelines for the Primary Prevention of Stroke: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline
The aim of this updated statement is to provide comprehensive and timely evidence-based recommendations on the prevention of stroke among individuals who have not previously experienced a stroke or transient ischemic attack. Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, and antithrombotic treatments for preventing thrombotic and thromboembolic stroke. Further recommendations are provided for genetic and pharmacogenetic testing and for the prevention of stroke in a variety of other specific circumstances, ...
Source: Stroke - November 24, 2014 Category: Neurology Authors: Meschia, J. F., Bushnell, C., Boden-Albala, B., Braun, L. T., Bravata, D. M., Chaturvedi, S., Creager, M. A., Eckel, R. H., Elkind, M. S. V., Fornage, M., Goldstein, L. B., Greenberg, S. M., Horvath, S. E., Iadecola, C., Jauch, E. C., Moore, W. S., Wilson Tags: AHA Statements and Guidelines AHA/ASA Guideline Source Type: research

Determinants of antithrombotic choice for patent foramen ovale in cryptogenic stroke
Conclusion: Both antithrombotic regimens are widely used for secondary stroke prevention in patients with CS and PFO. Radiologic and echocardiographic features were strongly associated with treatment choice, whereas conventional vascular risk factors were not. Prior observational studies are likely to be biased by confounding by indication.
Source: Neurology - November 17, 2014 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Weimar, C., Serena, J., Mattle, H. P., Nedeltchev, K., Mono, M.-L., Di Angelantonio, E., Elkind, M. S. V., Di Tullio, M. R., Homma, S., Michel, P., Meier, B., Furlan, A. J., Lutz, J. S., Kent, D. M. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Teaching NeuroImages: Hyperdense posterior cerebral artery sign
A 38-year-old man presented to the emergency department with right-sided weakness, sensory loss, and hemianopsia. CT head showed a left hyperdense posterior cerebral artery sign (HPCAS) (figure 1). CT angiogram of the head confirmed a left posterior cerebral artery (PCA) occlusion (figure 2). MRI demonstrated a left PCA infarct. Transesophageal echocardiogram revealed an atrial septal aneurysm and patent foramen ovale. He was treated with antiplatelet therapy. The HPCAS has been considered a marker for acute ischemia in the PCA territory.1 Recognizing the HPCAS on CT in acute stroke may help in the diagnosis and treatment ...
Source: Neurology - November 10, 2014 Category: Neurology Authors: Capampangan, D. J., Lee-Ianotti, J. K., Riordan, K. C., Kramer, C. L. Tags: CT, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Paradoxical Consequence of Human Chorionic Gonadotropin Misuse
This report highlights the potential complications of hCG therapy, particularly when used for unapproved indications and without medical supervision.
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2014 Category: Neurology Authors: Mehmet Yasir Pektezel, Demet Funda Bas, Mehmet Akif Topcuoglu, Ethem Murat Arsava Tags: Case Report Source Type: research

Key Blood Chemistry Changes Seen After PFO Closure Key Blood Chemistry Changes Seen After PFO Closure
The findings suggest there's more to the risk for stroke associated with patent foramen ovale than simply allowing clots to pass to the brain. Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - October 29, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Recurrent Stroke and Patent Foramen Ovale: A Systematic Review and Meta-Analysis Clinical Sciences
Conclusions— Our findings indicate that medically treated patients with PFO do not have a higher risk for recurrent cryptogenic cerebrovascular events, compared with those without PFO. No relation between the degree of PFO and the risk of future cerebrovascular events was identified.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Katsanos, A. H., Spence, J. D., Bogiatzi, C., Parissis, J., Giannopoulos, S., Frogoudaki, A., Safouris, A., Voumvourakis, K., Tsivgoulis, G. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Prevalence of migraine headache in an in‐patient stroke population
ConclusionsThe prevalence of migraine in this hospital‐based stroke cohort was comparable to the estimated prevalence of migraine usually described in population studies. In our study population, the prevalence of migraine with aura was higher than expected. The increased prevalence of PFO in patients with migraine headache corresponds well to previous population studies.
Source: Acta Neurologica Scandinavica - October 23, 2014 Category: Neurology Authors: M. Lantz, K. Kostulas, E. Waldenlind, C. Sjöstrand Tags: Original Article Source Type: research

Diagnostic and Therapeutic Value of Echocardiography during the Acute Phase of Ischemic Stroke
Conclusions: Echocardiography, as currently practiced in our stroke unit, allows detection of CSE in one patient in five, and leads to change in therapy in half of these cases. Our results suggest that TTE should be used for all patients admitted for IS, and to limit the use of TEE to younger patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2014 Category: Neurology Authors: Marie Gaudron, Isabelle Bonnaud, Aaurélia Ros, Frédéric Patat, Bertrand de Toffol, Bruno Giraudeau, Séverine Debiais Tags: Original Articles Source Type: research

Diagnostic Yield of Pelvic Magnetic Resonance Venography in Patients With Cryptogenic Stroke and Patent Foramen Ovale Clinical Sciences
Conclusions— Among patients with ischemic stroke/transient ischemic attack and patent foramen ovale, the majority of detected DVTs were in LE veins rather than the pelvic veins and did not differ by stroke subtype. The routine inclusion of pelvic magnetic resonance venography in the diagnostic evaluation of CS warrants further prospective investigation.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Liberman, A. L., Daruwalla, V. J., Collins, J. D., Maas, M. B., Botelho, M. P. F., Ayache, J. B., Carr, J., Ruff, I., Bernstein, R. A., Alberts, M. J., Prabhakaran, S. Tags: Deep vein thrombosis, Other diagnostic testing, Acute Cerebral Infarction, Embolic stroke Clinical Sciences Source Type: research

RoPE: A safety line but tangles remain
In our health care system, we strive to provide the right patients with the right care at the right time. The charter of the Institute of Medicine Roundtable on Value & Science-Driven Health Care states: "By the year 2020, 90% of clinical decisions will be supported by accurate, timely, and up-to-date clinical information, and will reflect the best available evidence."1 The optimal management of patients with ischemic stroke and a patent foramen ovale (PFO) remains unclear, although we applaud the novel analytic approach from the Tufts-based international consortium.2
Source: Neurology - July 14, 2014 Category: Neurology Authors: Carroll, J. D., Fuller, C. J. Tags: EDITORIALS Source Type: research

Recurrent stroke predictors differ in medically treated patients with pathogenic vs other PFOs
Conclusion: Predictors of recurrence differ when PFO relatedness is classified by the RoPE score, suggesting that patients with CS and PFO form a heterogeneous group with different stroke mechanisms. Echocardiographic features were only associated with recurrence in the high RoPE score group.
Source: Neurology - July 14, 2014 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Weimar, C., Mas, J.-L., Serena, J., Di Angelantonio, E., Papetti, F., Homma, S., Mattle, H. P., Nedeltchev, K., Mono, M.-L., Jaigobin, C., Michel, P., Elkind, M. S. V., Di Tullio, M. R., Lutz, J. S., Griffith, J., Kent, D. M. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline
The aim of this updated guideline is to provide comprehensive and timely evidence-based recommendations on the prevention of future stroke among survivors of ischemic stroke or transient ischemic attack. The guideline is addressed to all clinicians who manage secondary prevention for these patients. Evidence-based recommendations are provided for control of risk factors, intervention for vascular obstruction, antithrombotic therapy for cardioembolism, and antiplatelet therapy for noncardioembolic stroke. Recommendations are also provided for the prevention of recurrent stroke in a variety of specific circumstances, includi...
Source: Stroke - June 23, 2014 Category: Neurology Authors: Kernan, W. N., Ovbiagele, B., Black, H. R., Bravata, D. M., Chimowitz, M. I., Ezekowitz, M. D., Fang, M. C., Fisher, M., Furie, K. L., Heck, D. V., Johnston, S. C., Kasner, S. E., Kittner, S. J., Mitchell, P. H., Rich, M. W., Richardson, D., Schwamm, L. H Tags: AHA Statements and Guidelines AHA/ASA Guideline Source Type: research

Spreading Depolarization May Link Migraine and Stroke.
Abstract Migraine increases the risk of stroke, particularly in young and otherwise healthy adults. Being the most frequent neurological condition, migraine prevalence is on a par with that of other common stroke risk factors, such as diabetes or hypertension. Several patterns of association have emerged: (1) migraine and stroke share a common association (eg, vasculopathies, patent foramen ovale, or pulmonary A-V malformations); (2) injury to the arterial wall such as acute arterial dissections can present as migraine aura attacks or stroke; (3) strokes rarely develop during a migraine attack, as described for "m...
Source: Headache - June 10, 2014 Category: Neurology Authors: Eikermann-Haerter K Tags: Headache Source Type: research

Spreading Depolarization May Link Migraine and Stroke
Migraine increases the risk of stroke, particularly in young and otherwise healthy adults. Being the most frequent neurological condition, migraine prevalence is on a par with that of other common stroke risk factors, such as diabetes or hypertension. Several patterns of association have emerged: (1) migraine and stroke share a common association (eg, vasculopathies, patent foramen ovale, or pulmonary A‐V malformations); (2) injury to the arterial wall such as acute arterial dissections can present as migraine aura attacks or stroke; (3) strokes rarely develop during a migraine attack, as described for “migrainous stro...
Source: Headache: The Journal of Head and Face Pain - May 1, 2014 Category: Neurology Authors: Katharina Eikermann‐Haerter Tags: Review Article Source Type: research

Differential Lesion Patterns on T2-weighted Magnetic Resonance Imaging and Fluid-attenuated Inversion Recovery Sequences in Cryptogenic Stroke Patients with Patent Foramen Ovale
Background: The present study aimed to determine lesion patterns and the stroke mechanisms in cryptogenic ischemic stroke patients with patent foramen ovale (PFO) on T2-weighted magnetic resonance imaging (T2WI) and fluid-attenuated inversion recovery (FLAIR) sequences combined.Methods: In this retrospective study, 38 patients with cryptogenic stroke and an isolated PFO compared with 51 cryptogenic stroke patients without PFO were evaluated and their characteristics of lesion patterns on T2WI and FLAIR sequences combined were investigated. The number, distribution of small ischemic lesions, and the frequency of multiple sm...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2014 Category: Neurology Authors: Yang-Yang Huang, Bei Shao, Xian-Da Ni, Jian-Ce Li Tags: Original Articles Source Type: research