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Total 22 results found since Jan 2013.

Improving sleep and learning in rehabilitation after stroke, part 2 (INSPIRES2): study protocol for a home-based randomised control trial of digital cognitive behavioural therapy (dCBT) for insomnia
Introduction Consolidation of motor skill learning, a key component of rehabilitation post-stroke, is known to be sleep dependent. However, disrupted sleep is highly prevalent after stroke and is often associated with poor motor recovery and quality of life. Previous research has shown that digital cognitive behavioural therapy (dCBT) for insomnia can be effective at improving sleep quality after stroke. Therefore, the aim of this trial is to evaluate the potential for sleep improvement using a dCBT programme, to improve rehabilitation outcomes after stroke. Methods and analysis We will conduct a parallel-arm randomised c...
Source: BMJ Open - April 6, 2023 Category: General Medicine Authors: Weightman, M., Robinson, B., Fallows, R., Henry, A. L., Kyle, S. D., Garratt, E., Pick, A., Teal, R., Ajina, S., Demeyere, N., Espie, C. A., Seymour, B., Johansen-Berg, H., Fleming, M. K. Tags: Open access, Rehabilitation medicine Source Type: research

Acori Tatarinowii Rhizoma: A comprehensive review of its chemical composition, pharmacology, pharmacokinetics and toxicity
Acori Tatarinowii Rhizoma (ATR, Shi Chang Pu in Chinese), a natural product with multiple targets in various diseases. This review provides the comprehensive summary of the chemical composition, pharmacological effects, pharmacokinetics parameters and toxicity of ATR. The results indicated that ATR possesses a wide spectrum of chemical composition, including volatile oil, terpenoids, organic acids, flavonoids, amino acids, lignin, carbohydrates and so on. Accumulating evidence from various studies has shown that ATR exerts a wide range of pharmacological properties, including protecting nerve cells, alleviating learning an...
Source: Frontiers in Pharmacology - March 16, 2023 Category: Drugs & Pharmacology Source Type: research

AI Empowered Virtual Reality Integrated Systems for Sleep Stage Classification and Quality Enhancement
Insomnia is a common public health problem and an open biomedical research topic. Insomnia results in various health problems, including memory decline, decreases concentration and weakens problem-solving ability. The insufficient sleep also leads to skin ageing, heart disease, high blood pressure, arrhythmia and stroke. While it remains as a global health concern, sleep quality improvement using modern technologies, such as machine learning, classification technologies, virtual reality (VR), becomes an open and hot research problem. These modern technologies offer new curing solutions under certain conditions. In this pap...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - June 14, 2022 Category: Neuroscience Source Type: research

Janssen to Present the Strength and Promise of its Hematologic Malignancies Portfolio and Pipeline at ASH 2021
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH...
Source: Johnson and Johnson - November 5, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

One-Third of COVID-19 Survivors May Develop a Neuropsychiatric Disorder Within Months of Infection
One-third of individuals diagnosed with COVID-19 developed a psychiatric or neurological problem within six months of their diagnosis, according to astudy published Tuesday inThe Lancet Psychiatry. The prevalence of a post-COVID neurologic or psychiatric diagnosis was even greater among individuals with severe illness who had required hospitalization.“Given the size of the pandemic and the chronicity of many of the diagnoses and their consequences (for example, dementia, stroke, and intracranial hemorrhage), substantial effects on health and social care systems are likely to occur,” wrote Maxime Taque, Ph.D., of the Un...
Source: Psychiatr News - April 7, 2021 Category: Psychiatry Tags: anxiety COVID-19 electronic health records hospitalizations mood disorders neuropsychiatric disorders The Lancet Psychiatry Source Type: research

Q & A: UArizona Expert Talks Sleep Apnea, ' Coronasomnia ' and Snoozing in Space
Q&A: UArizona Expert Talks Sleep Apnea,'Coronasomnia' and Snoozing in Space UArizona sleep researchers are working to tackle insomnia, sleep apnea and pandemic-induced " coronasomnia. " Mikayla Mace Kelley Today University Communicationsman-5522892_1920.jpgHealthCollege of Medicine - TucsonCollege of ScienceCOVID-19 Media contact(s)Mikayla Mace Kelley University Communicationsmikaylamace@arizona.edu520-621-1878 Researcher contact(s)Sairam Parthasarathy College of Medicine – Tucsonspartha1@arizona.edu520-626-8309Sleep apnea and insomnia have been on the rise for decades, but the COVID-19 pandemic ha...
Source: The University of Arizona: Health - March 15, 2021 Category: Universities & Medical Training Authors: mikaylamace Source Type: research

Characteristic of Clinical Studies on Baduanjin during 2000-2019: A Comprehensive Review.
Authors: Zhou J, Yu Y, Cao B, Li X, Wu M, Wen T, Xiong Y, Jia J, Zhao Y Abstract To date, a growing number of clinical studies have demonstrated the safety and health benefits from Baduanjin intervention. Based on this, our objective is to systematically retrieve and summarize the clinical studies on Baduanjin, with a view to providing more evidence-based evidence in support of the application of Baduanjin for healthcare, and to identify the shortcomings of existing research and provide feasibility suggest for further clinical research. Both four English language and four Chinese language electronic databases were ...
Source: Evidence-based Complementary and Alternative Medicine - November 6, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study
Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, unders...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

10 Biggest Myths About Sleeping, According To Researchers
(CNN) — Hey, sleepyheads. What you believe about sleep may be nothing but a pipe dream. Many of us have notions about sleep that have little basis in fact and may even be harmful to our health, according to researchers at NYU Langone Health’s School of Medicine, who conducted a study published Tuesday in the journal Sleep Health. “There’s such a link between good sleep and our waking success,” said lead study investigator Rebecca Robbins, a postdoctoral research fellow in the Department of Population Health at NYU Langone Health. “And yet we often find ourselves debunking myths, whether ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 16, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Healthwatch News CNN Sleep Source Type: news

How to stay healthy and happy through the decades
Successful aging can be the norm, says UCLA psychology professor Alan Castel in his new book, “Better with Age: The Psychology of Successful Aging” (Oxford University Press). Castel sees many inspiring role models of aging. French Impressionist Claude Monet, he notes, began his beloved water lily paintings at age 73.Castel cites hundreds of research studies, including his own, combined with personal accounts from older Americans, including Maya Angelou, Warren Buffett, John Wooden, Bob Newhart, Frank Gehry, David Letterman, Jack LaLanne, Jared Diamond, Kareem Abdul-Jabbar, John Glenn and Vin Scully.Castel notes that ar...
Source: UCLA Newsroom: Health Sciences - November 1, 2018 Category: Universities & Medical Training Source Type: news

Sleep biology discovery could lead to new insomnia treatments that don ’t target the brain
UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation — a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.The scientists report that increasing the level of Bmal1 — a critical master gene that regulates sleep patterns — in skeletal muscle makes mice resistant to sleep deprivation.“When we first saw the importance of the muscle, we were surprised,” said senior author Ketema Paul, UCLA associate professor of integrative biolo...
Source: UCLA Newsroom: Health Sciences - August 10, 2017 Category: Universities & Medical Training Source Type: news

What Causes Hyperammonemia?
Discussion Reye’s syndrome (RS)is named for Dr. Douglas Reye who along with Drs. G. Morgan and J. Baral described encephalopathy and fatty accumulation and degeneration in children in a 1963 Lancet article. RS usually affects children but can occur at all ages. All organs can be affected but the liver and brain are primarily affected causing liver failure and encephalopathy as toxic metabolites (especially ammonia) accumulate, and intracranial hypertension and cerebral edema occurs. As the ammonia levels begin to rise (> 100 mg/dL) patients lose their appetite, have nausea and emesis and mental status changes whic...
Source: PediatricEducation.org - February 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Are You Getting Older - Or Are You Getting Sleep Apnea?
By Brandon R. Peters, MD As my 81-year-old grandma likes to remind me on occasion, "It's hell to get old." More than a nuisance, the cumulative decline that comes with aging can significantly compromise one's quality of life and health. What if some of the problems so often associated with growing older didn't need to occur? Better yet, what if some of these physical and mental impairments could be reversed? Consider the role of sleep apnea as an unexpected contributor to many ailments erroneously attributed to aging and the reversals possible with effective treatment. Sleep Changes with Age It is clear that sleep chang...
Source: Healthy Living - The Huffington Post - November 15, 2016 Category: Consumer Health News Source Type: news

10 Experiments at the Forefront of Sleep Science
As part of the team at Experiment.com, a crowdfunding platform for science, I get to talk to scientists all the time. I've been an insomniac and poor sleeper all my life, so I decided to run a Sleep Challenge Grant to launch a batch of sleep experiments together on the site. Here's what I'm learning from 10 scientists at the forefront of sleep research: Men who go to sleep late have more sex. "Evening men," who naturally wake up later and go to sleep later, tend to have higher mating success but lower success in social settings like school or business. Dr. Christoph Randler wants to investigate whether there are clues fo...
Source: Healthy Living - The Huffington Post - June 9, 2016 Category: Consumer Health News Source Type: news

Why We Study Sleep
This post is adapted from a speech delivered at a Fireside Chat between Arianna Huffington and Andre Iguodala on April 11, 2016 at Stanford University. You can watch the event here. Before introducing our famous guests, as director of the Center for Sleep Sciences and Medicine, I have been asked to introduce the topic of sleep and sleep disorders and why we should bother to study sleep. This is not difficult for me as sleep is my passion. The first reason for studying sleep is simply that sleep is one of the last remaining mysteries in biology. We still don't understand why a typical human has to spend 25 years of life sle...
Source: Science - The Huffington Post - April 14, 2016 Category: Science Source Type: news