10 Experiments at the Forefront of Sleep Science
As part of the team at Experiment.com, a crowdfunding platform for science, I get to talk to scientists all the time. I've been an insomniac and poor sleeper all my life, so I decided to run a Sleep Challenge Grant to launch a batch of sleep experiments together on the site. Here's what I'm learning from 10 scientists at the forefront of sleep research: Men who go to sleep late have more sex. "Evening men," who naturally wake up later and go to sleep later, tend to have higher mating success but lower success in social settings like school or business. Dr. Christoph Randler wants to investigate whether there are clues for fitness in the sperm and saliva of these men that would be an evolutionary explanation for this phenotype. The technology of Eternal Sunshine of the Spotless Mind might be real very soon. For decades, scientists have known that preventing Rapid Eye Movement sleep helps patients with depression, to the point where antidepressant drugs work by specifically disrupting or impacting REM sleep. Today, scientists have identified the neurons in the ventral medulla, the area of the brain that controls sleep, that can make REM sleep turn on or off. A new technique called optogenetics is telling us how exactly sleep impacts mood and depression. Infancy is the most interesting period to study sleep and the period we know nothing about. So much cognitive development takes place in a baby during its first year, but we've been held back in studying the relati...
ConclusionLET is a rare cutaneous lupus-specific lesion that may be associated with SLE. AITD, hypothyroidism in particular, could be an initial presentation of SLE. Increased awareness and early diagnosis of such clinical presentations may improve patient outcomes.
The objective of this research article was to assess the trend of hospitalization, epidemiological characteristics and economic burden in the young adult, aged 18–45 years, presenting with atrial fibrillation.MethodsHospitalization data from the National Inpatient Sample between 2005 and 2015 were used to analyze prevalence of risk factors and financial burden in young adults with atrial fibrillation.ResultsFrom 2005 to 2015, a total of 260,080 admissions were included in the study. From 2005 to 2015, there was a decreasing trend of total admissions with atrial fibrillation among the age group of 18–45 years co...
CONCLUSIONS: Despite its limitations, the present meta-analysis found no clear differences in patient morbidity between the different flap designs. PMID: 32062667 [PubMed - as supplied by publisher]
Conclusion CAS in maintenance hemodialysis patients may be feasible and effective for the prevention of stroke with proper case selection, appropriate technique and strict perioperative management. The most common causes of death during the follow-up of maintenance hemodialysis patients were diseases other than stroke. PMID: 32062623 [PubMed - in process]
Do children of depressed parents exhibit greater parent- and self-reported sleep disturbance compared to those without any parental psychopathology?Journal of Pediatric Psychology
Spinal cord stimulation is an option for the management of chronic neuropathic pain, but is the pain relief obtained the result of a placebo effect?Pain
In conclusion, parents and coaches should be properly re-educated to help improve lower back, upper extremity, and shoulder pain among young basketball players. PMID: 32062615 [PubMed - in process]
BEST supplements for sleep: With a staggering 95 percent of people suffering with insomnia reporting low energy levels and over 75 percent of these experiencing poor concentration at work, finding a natural alternative supplement to ensure a good night's rest is crucial for many. According to studies, what is the best supplement to take to help you get some crucial shut eye?
Authors: He P, Hu Y, Huang C, Wang X, Zhang H, Zhang X, Dai H, Wang R, Gao Y Abstract Gastrodia elata is a traditional herbal medicine that has been used for centuries to treat rheumatism. Previous studies have confirmed that ethanol extracts of Gastrodia elata have anti-inflammatory and antioxidant activities, and the n-butanol fraction exerts a higher inhibitory effect. However, the in vivo anti-inflammatory effects of Gastrodia elata have not been evaluated. Thus, we assessed the therapeutic effect of the n-butanol extract of Gastrodia elata (BGE) on complete Freund's adjuvant- (CFA-) induced arthritis rats whic...
The objectives of this paper are to review current guidelines for the pharmacological management of DPN and to discuss research rel evant to the further development of pharmacological recommendations for the treatment of diabetic neuropathy.SummaryDiabetic neuropathy is a highly prevalent, disabling condition, the management of which is associated with significant costs. Evidence supports the use of specific anticonvulsants and antidepressants for pain management in patients with diabetic peripheral neuropathy. All current guidelines advise a personalised approach with a low ‐dose start that is tailored to the maximum re...
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