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Condition: Hemorrhagic Stroke
Procedure: Anesthesia

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Total 259 results found since Jan 2013.

Initial Experience With the Next-Generation Resolute Onyx Zotarolimus-Eluting Stent in Symptomatic Intracranial Atherosclerotic Disease
Conclusion: The use of R-onyx DES in the treatment of sICAD is safe with high technical success rates. Large prospective multicenter trials with long-term follow-up are warranted.
Source: Frontiers in Neurology - September 29, 2020 Category: Neurology Source Type: research

Emergency Carotid Endarterectomy Instead of Carotid Artery Stenting Reduces Delayed Hemorrhage in Thrombectomy Stroke Patients
ConclusionThe use of CEA is a  feasible alternative to CAS in acute stroke and has the advantage that DAPT/GpIIb/IIIa inhibitors are not needed. All PH2 in CEA patients occurred during the intervention, implying that hemorrhage in this group is likely to be caused by reperfusion injury, whereas delayed hemorrhage is likely to b e caused by DAPT/GpIIb/IIIa inhibitors.
Source: Clinical Neuroradiology - September 16, 2020 Category: Neurology Source Type: research

Idarucizumab for dabigatran reversal in daily clinical practice: A case series
CONCLUSION Our first experiences with idarucizumab use in daily-care settings support a rapid and efficient decrease in the anticoagulant effect of dabigatran in emergency situations. Late re-occurrence of dabigatran effect was noted in a subset of patients with severe renal failure.
Source: European Journal of Anaesthesiology - September 12, 2020 Category: Anesthesiology Tags: Coagulation Source Type: research

Preliminary results of posterior contralateral cervical 7 nerve transposition in the treatment of upper limb plegia after a stroke
ConclusionThe distance of nerve transposition can be shortened by a posterior vertebral approach operation, where the contralateral C7 nerve can be anastomosed directly with the ipsilateral C7 nerve which may be effective for nerve regeneration and functional recovery. However, this conclusion still needs further research and verification.
Source: Brain and Behavior - September 5, 2020 Category: Neurology Authors: Jingyu Guan, Jun Lin, Xueqing Guan, Qiang Jin, Lei Chen, Qiao Shan, Jianheng Wu, Xiaodong Cai, Doudou Zhang, Wei Tao, Fuyong Chen, Yili Chen, Shaofeng Yang, Youwu Fan, Heming Wu, Han Zhang Tags: ORIGINAL RESEARCH Source Type: research

MENA-SINO Consensus Statement on Implementing Care Pathways for Acute Neurovascular Emergencies During the COVID-19 Pandemic
In the unprecedented current era of the COVID-19 pandemic, challenges have arisen in the management and interventional care of patients with acute stroke and large vessel occlusion, aneurysmal subarachnoid hemorrhage, and ruptured vascular malformations. There are several challenges facing endovascular therapy for stroke, including shortages of medical staff who may be deployed for COVID-19 coverage or who may have contracted the infection and are thus quarantined, patients avoiding early medical care, a lack of personal protective equipment, delays in door-to-puncture time, anesthesia challenges, and a lack of high-intens...
Source: Frontiers in Neurology - August 24, 2020 Category: Neurology Source Type: research

Acute thalamic haemorrhagic stroke after combined spinal–epidural anaesthesia in pregnancy: A case report
No abstract available
Source: European Journal of Anaesthesiology - August 13, 2020 Category: Anesthesiology Tags: Correspondence Source Type: research

Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography for Image Guidance in Percutaneous Patent Foramen Ovale Closure.
Conclusions: ICE-guided PFO device closure is quicker and less hazardous in terms of radiation exposure than the TEE-guided procedure, with similar procedural outcomes and duration of hospital stay. PMID: 32784843 [PubMed - in process]
Source: Medicina (Kaunas) - August 8, 2020 Category: Universities & Medical Training Authors: Moon J, Park Y, Park SJ, Oh PC, Jang AY, Chung WJ, Kang WC Tags: Medicina (Kaunas) Source Type: research

L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model.
Abstract L-3-n-butylphthalide(NBP), a compound found in Apium graveolens Linn seed extracts, has a therapeutic effect on acute ischemic stroke. The pathological inflammatory pathways and consequent brain edema in intracerebral hemorrhage (ICH) share some similar characteristics with ischemic stroke. We hypothesized that NBP has anti-inflammatory and therapeutic effects on rats with ICH. ICH was induced by an infusion of bacterial collagenase type IV into the unilateral striatum of anesthetized rats. The therapeutic effect of NBP was measured by assessing neurological function, brain water content, blood-brain barr...
Source: Aging - June 20, 2020 Category: Biomedical Science Authors: Zeng Z, Gong X, Hu Z Tags: Aging (Albany NY) Source Type: research

Profile of cerebrovascular accidents in subjects with or without type 2 diabetes mellitus in intensive care units of tertiary care centre
Conclusions: A greater incidence of anterior circulation ischemic stroke, and recurrent strokes occur in patients with DM.
Source: Journal of Anaesthesiology Clinical Pharmacology - June 14, 2020 Category: Anesthesiology Authors: Dinesh Jain Mukesh Chawala Birinder S Paul Naveen Mittal Aayush Jain Sandeep Puri Source Type: research

Effect of Intra-arterial Nimodipine on Cerebral Oxygen Saturation and Systemic Hemodynamic Indices in Patients With Cerebral Vasospasm: A Prospective Cohort Study
This study assessed the effect of IaN on rScO2 and systemic hemodynamic indices during IaN therapy for cerebral vasospasm after aSAH. Methods: This prospective cohort study was conducted in 20 patients over sixteen month period after ethics committee approval and informed consent. Patients with angiographic evidence of vasospasm received IaN 3mg over 30 minutes in the spastic vessels. Data regarding rScO2 heart rate (HR), mean blood pressure (MBP) cardiac index (CI), stroke volume index (SVI), stroke volume variation (SVV), and total peripheral resistance index (TPRI) were collected during IaN treatment. The primary out...
Source: Journal of Neurosurgical Anesthesiology - March 10, 2020 Category: Anesthesiology Tags: Short Reports Source Type: research

Proposed Definition of Experimental Secondary Ischemia for Mouse Subarachnoid Hemorrhage
AbstractInconsistency in outcome parameters for delayed cerebral ischemia (DCI) makes it difficult to compare results between mouse studies, in the same way inconsistency in outcome parameters in human studies has for long obstructed adequate comparison. The absence of an established definition may in part be responsible for the failed translational results. The present article proposes a standardized definition for DCI in experimental mouse models, which can be used as outcome measure in future animal studies. We used a consensus-building approach to propose a definition for “experimental secondary ischemia” (ESI) in ...
Source: Translational Stroke Research - March 8, 2020 Category: Neurology Source Type: research

Treatment targets based on autoregulation parameters in neurocritical care patients
Purpose of review This review summarizes the physiological basis of autoregulation-oriented therapy in critically ill patients, with a particular emphasis on individual targets based on parameters that describe autoregulation of cerebral blood flow. Recent findings The concepts of optimal cerebral perfusion (CPPopt) and arterial pressures (ABPopt), which both take advantage of continuous measures of cerebral autoregulation, recently have been introduced into clinical practice. It is hypothesized that if both pressures are used as individual targets and followed, the incidence and severity of dysautoregulation will dim...
Source: Current Opinion in Critical Care - March 6, 2020 Category: Nursing Tags: ACUTE NEUROLOGICAL PROBLEMS: Edited by Peter Le Roux Source Type: research

Long-term Clinical Outcomes of Elective Carotid Artery Stenting in Patients Undergoing Maintenance Hemodialysis.
Conclusion CAS in maintenance hemodialysis patients may be feasible and effective for the prevention of stroke with proper case selection, appropriate technique and strict perioperative management. The most common causes of death during the follow-up of maintenance hemodialysis patients were diseases other than stroke. PMID: 32062623 [PubMed - in process]
Source: Internal Medicine - February 19, 2020 Category: Internal Medicine Tags: Intern Med Source Type: research

The effect of positive end-expiratory pressure on stroke volume variation: an experimental study in dogs.
Abstract Stroke volume variation (SVV) may be affected by ventilation settings. However, it is unclear whether positive end-expiratory pressure (PEEP) affects SVV independently of the effect of driving pressure. We aimed to investigate the effect of driving pressure and PEEP on SVV under various preload conditions using beagle dogs as the animal model. We prepared three preload model, baseline, mild and moderate hemorrhage model. Mild and moderate hemorrhage models were created in 9 anesthetized, mechanically ventilated dogs by sequentially removing 10 mL/kg, and then an additional 10 mL/kg of blood, respectively....
Source: Clinical and Experimental Pharmacology and Physiology - January 25, 2020 Category: Drugs & Pharmacology Authors: Nakashima T, Kawazoe Y, Iseri T, Miyamoto K, Fujimoto Y, Kato S Tags: Clin Exp Pharmacol Physiol Source Type: research

Isoflurane attenuates carbogen-induced blood–brain barrier disruption independent of body temperature in mice and rats
In conclusion, isoflurane protected against BBB disruption caused by carbogen inhalation in mice and rats, but unlike isoflurane-mediated protection against ischemic BBB disruption, the effect could not be explained by anesthesia-induced hypothermia.
Source: NeuroReport - January 15, 2020 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research