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Condition: Hemorrhagic Stroke
Procedure: Anesthesia

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Total 259 results found since Jan 2013.

Ischemic Stroke Due to Heparin-induced Thrombocytopenia During Severe COVID-19 Infection
Intern Med. 2022 Jul 5. doi: 10.2169/internalmedicine.9531-22. Online ahead of print.ABSTRACTA 53-year-old woman with severe coronavirus disease 2019 (COVID-19) pneumonia was admitted and treated with intravenous unfractionated heparin for thromboprophylaxis under general anesthesia with mechanical ventilation. She developed right hemiparesis after hospitalization due to a large hemorrhagic infarction. Her platelet count decreased from 243,000/μL at administration to 121,000/μL. Anti-platelet factor 4-heparin antibody testing was positive according to a latex immunoturbidimetric assay. She was therefore diagnosed with he...
Source: Internal Medicine - July 6, 2022 Category: Internal Medicine Authors: Yasutaka Murakami Shuhei Okazaki Makoto Yamamoto Rei Sakurai Jyunki Jinno Tatsuhiko Ozono Kensuke Ikenaka Yasufumi Gon Kenichi Todo Tsutomu Sasaki Haruhiko Hirata Akinori Uchiyama Hideki Mochizuki Source Type: research

Procedural and Methodological Quality in Preclinical Stroke Research –A Cohort Analysis of the Rat MCAO Model Comparing Periods Before and After the Publication of STAIR/ARRIVE
In conclusion, the frequency of periinterventional monitoring has decreased over time. Some general methodological quality aspects, however, partially have increased. CBF measurement–the gold standard for ischemia verification-was applied rarely. Despite the growing recognition of current guidelines such as STAIR and ARRIVE (both widely approved in 2019) reporting, methods and procedures mostly do not follow these guidelines. These deficits may contribute to the translational failure of preclinical stroke research in search for neuroprotective therapies.
Source: Frontiers in Neurology - May 30, 2022 Category: Neurology Source Type: research

Effect of Gastrointestinal Hemorrhage on Outcome After Endovascular Treatment in Acute Basilar Artery Occlusion
ConclusionThis study concluded that GIH is not uncommon after EVT in patients with acute BAO and is associated with worse functional disability and higher mortality.
Source: Frontiers in Neurology - April 28, 2022 Category: Neurology Source Type: research

High-Risk Pulmonary Embolism After Hemorrhagic Stroke: Management Considerations During Catheter-Directed Interventional Therapy
SUMMARY
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 6, 2022 Category: Anesthesiology Authors: Ferenc Rabai, Joseph E. LaGrew, Michael Lazarowicz, Gregory M. Janelle, Nicolai Goettel, Lawrence J. Caruso Source Type: research

Data from New VOYAGER PAD Analyses at ACC.22 Reinforce Benefit of XARELTO ® (rivaroxaban) Plus Aspirin in Patients with Peripheral Artery Disease (PAD) and Various Co-Morbid Conditions
RARITAN, N.J., April 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from new analyses from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefit of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) in reducing severe vascular events in patients with PAD after lower-extremity revascularization (LER), a procedure that restores blood flow to the legs. Data from the two analyses demonstrate the role that the XARELTO® vascular dose plays in PAD patients with and without chronic kidney disease (CKD) and in PAD patients with and ...
Source: Johnson and Johnson - April 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Comparison of carbetocin as a bolus or an infusion with prophylactic phenylephrine on maternal heart rate during Cesarean delivery under spinal anesthesia: a double-blinded randomized controlled trial
CONCLUSION: Carbetocin infused over ten minutes did not reduce the magnitude of maternal heart rate variation but delayed its occurrence. This finding could be relevant to the anesthesiologist caring for parturients in whom a slight increase in maternal heart rate is clinically undesirable.STUDY REGISTRATION: www.CLINICALTRIALS: gov (NCT03404544); registered 19 January 2018.PMID:35352277 | DOI:10.1007/s12630-022-02227-y
Source: Canadian Journal of Anaesthesia - March 30, 2022 Category: Anesthesiology Authors: Marie- Ève Boisselle Val érie Vasiliki Zaphiratos Annik Fortier Philippe Richeb é Christian Loubert Source Type: research

Role of Dexmedetomidine in Aneurysmal Subarachnoid Hemorrhage: A Comprehensive Scoping Review
Dexmedetomidine (DEX), an α2-adrenergic agonist, has been widely used for anesthesia, pain control, and intensive care unit sedation. Besides sleep-like sedation, DEX has many other beneficial effects, such as anti-inflammation, antioxidation, and anticell death. Subarachnoid hemorrhage (SAH), a severe and potentially fatal form of stroke, is a complex disease that is divided into 2 phases: early brain injury and delayed cerebral ischemia. In each phase, several pathologic changes are involved, including disturbed intracranial homeostasis, metabolic failure, blood-brain barrier damage, vasospasm, microthrombosis, and cort...
Source: Journal of Neurosurgical Anesthesiology - March 15, 2022 Category: Anesthesiology Tags: Review Articles Source Type: research

Hemoglobin Concentration May Influence the Incidence of Postoperative Transient Neurological Events in Patients With Moyamoya After Extracranial-intracranial Arterial Bypass: A Retrospective Single Center Experience
Background: Moyamoya is a rare condition characterized by cerebral angiographic findings of intracranial carotid artery stenosis with abnormal net-like vessels in the brain, and often presents as transient ischemic attacks or intracranial hemorrhage. Revascularization in the form of extracranial-intracranial (EC-IC) artery bypass has demonstrated efficacy in preventing ischemic attacks and intracranial hemorrhage, although it is associated with a relatively high rate of perioperative ischemic and hemorrhagic stroke. This retrospective analysis aims to evaluate the possible association between postoperative hemoglobin (...
Source: Journal of Neurosurgical Anesthesiology - March 15, 2022 Category: Anesthesiology Tags: Short Reports Source Type: research

Local anesthesia as a distinct comparator versus conscious sedation and general anesthesia in endovascular stroke treatment: a systematic review and meta-analysis
Conclusion LA without sedation was not significantly superior to CS or GA in improving outcomes when performing EVT for AIS. However, the quality of the included studies impaired interpretation, and inclusion of an LA arm in future well designed multicenter, randomized controlled trials is warranted.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Butt, W., Dhillon, P. S., Podlasek, A., Malik, L., Nair, S., Hewson, D., England, T. J., Lenthall, R., McConachie, N. Tags: Ischemic stroke Source Type: research

General Anesthesia vs. Local Anesthesia During Endovascular Treatment for Acute Large Vessel Occlusion: A Propensity Score-Matched Analysis
ConclusionIn the real-world setting, LA ± CS might provide more outcomes benefits than GA in patients with AIS-LVO during the procedure.
Source: Frontiers in Neurology - February 14, 2022 Category: Neurology Source Type: research

Endovascular therapy for acute ischemic stroke: The importance of blood pressure control, sedation modality and anti-thrombotic management to improve functional outcomes
Rev Neurol (Paris). 2022 Feb 4:S0035-3787(21)00778-5. doi: 10.1016/j.neurol.2021.09.012. Online ahead of print.ABSTRACTSince 2015, endovascular therapy (EVT) following intravenous thrombolysis (IVT) is the gold standard treatment for patients suffering from acute ischemic stroke (AIS) due to an anterior large vessel occlusion (LVO). Despite high recanalization rates, nearly half of successfully treated patients remain dependent at three months. This result underlines that other factors may have a prognostic value, such as blood pressure (BP) management, the sedation modality and anti-thrombotic strategy during and after EV...
Source: Revue Neurologique - February 8, 2022 Category: Neurology Authors: E Robichon B Ma ïer M Mazighi Source Type: research