Stroke RSS Page 18

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Condition: Hemorrhagic Stroke
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Total 499 results found since Jan 2013.

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial
Publication date: Available online 10 May 2016 Source:The Lancet Author(s): M Irem Baharoglu, Charlotte Cordonnier, Rustam Al-Shahi Salman, Koen de Gans, Maria M Koopman, Anneke Brand, Charles B Majoie, Ludo F Beenen, Henk A Marquering, Marinus Vermeulen, Paul J Nederkoorn, Rob J de Haan, Yvo B Roos Background Platelet transfusion after acute spontaneous primary intracerebral haemorrhage in people taking antiplatelet therapy might reduce death or dependence by reducing the extent of the haemorrhage. We aimed to investigate whether platelet transfusion with standard care, compared with standard care alone, re...
Source: The Lancet - May 11, 2016 Category: Journals (General) Source Type: research

Journal Club: Time trends in incidence, case fatality, and mortality of intracerebral hemorrhage
Intracerebral hemorrhage (ICH) remains one of the most catastrophic stroke subtypes, with high case-fatality rate and poor functional outcomes. In the Journal Club article "Time trends in incidence, case fatality, and mortality of intracerebral hemorrhage" by Jolink et al.,1 hospital and population registries were used to assess age- and sex-specific trends in incidence and case fatality of patients with ICH in the Netherlands. The study provides a significant epidemiologic contribution examining a large cohort of patients with ICH from 1980 to 2010. The authors report a decline in incidence, case-fatality, and mortality r...
Source: Neurology - May 15, 2016 Category: Neurology Authors: Charidimou, A., Morotti, A., Valenti, R., Giese, A.-K., Boulouis, G., Pasi, M., Roongpiboonsopit, D., Lauer, A., Xiong, L., Van Harten, T. W., Karadeli, H., Fotiadis, P., Jessel, M. J., Viswanathan, A. Tags: All Cerebrovascular disease/Stroke, All Education, Intracerebral hemorrhage RESIDENT AND FELLOW SECTION Source Type: research

Sulfonylurea Pretreatment and In-Hospital Use Does Not Impact Acute Ischemic Strokes (AIS) Outcomes Following Intravenous Thrombolysis
Preliminary studies have indicated that sulfonylurea drugs (SUD) may confer protection against cerebral swelling and hemorrhagic transformation in severe acute ischemic stroke (AIS). We sought to determine whether pretreatment and in-hospital use of SUD may be associated with better outcomes in diabetic AIS patients treated with intravenous thrombolysis (IVT).
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2016 Category: Neurology Authors: Georgios Tsivgoulis, Nitin Goyal, Sulaiman Iftikhar, Ramin Zand, Jason J. Chang, Lucas Elijovich, Anne W. Alexandrov, Marc D. Malkoff, Andrei V. Alexandrov Source Type: research

Noninvasive Neuromonitoring: Current Utility in Subarachnoid Hemorrhage, Traumatic Brain Injury, and Stroke
AbstractNoninvasive neuromonitoring is increasingly being used to monitor the course of primary brain injury and limit secondary brain damage of patients in the neurocritical care unit. Proposed advantages over invasive neuromonitoring methods include a lower risk of infection and bleeding, no need for surgical installation, mobility and portability of some devices, and safety. The question, however, is whether noninvasive neuromonitoring is practical and trustworthy enough already. We searched the recent literature and reviewed English-language studies on noninvasive neuromonitoring in subarachnoid hemorrhage, traumatic b...
Source: Neurocritical Care - December 20, 2016 Category: Neurology Source Type: research

Simultaneous Multiple Intracerebral Hemorrhages (SMICH) Clinical Sciences
Background and Purpose—Simultaneous multiple intracerebral hemorrhages (SMICHs) are uncommon. Few single-center studies have analyzed characteristics and outcome of SMICH. We analyzed clinical characteristics and outcome of SMICH patients from 2 comprehensive stroke centers.Methods—Baseline imaging from consecutive intracerebral hemorrhage (ICH) patients (n=1552) from Helsinki ICH study and Royal Melbourne Hospital ICH study was screened for SMICH. ICH pathogenesis was classified according to the structural lesion, medication, amyloid angiopathy, systemic/other disease, hypertension, undetermined classification system ...
Source: Stroke - February 26, 2017 Category: Neurology Authors: Teddy Y. Wu, Nawaf Yassi, Darshan G. Shah, Minmin Ma, Gagan Sharma, Jukka Putaala, Daniel Strbian, Bruce C.V. Campbell, Bernard Yan, Turgut Tatlisumak, Patricia M. Desmond, Stephen M. Davis, Atte Meretoja Tags: Intracranial Hemorrhage Original Contributions Source Type: research

In-hospital ischaemic stroke treated with intravenous thrombolysis or mechanical thrombectomy
The objective of this study is to compare outcomes in patients with IHS and community-onset strokes (COS) treated by recanalization therapy. We analysed data prospectively collected in consecutive patients treated by thrombolysis, thrombectomy, or both for cerebral ischemia at the Lille University Hospital. We compared four outcomes measures at 3 months in patients with IHS and COS: (1) modified Rankin scale (mRS) 0–1, (2) mRS 0–2, (3) death, and (4) symptomatic intracranial haemorrhage (ECASS 2 definition). Of 1209 patients, 64 (5.3%) had IHS, with an increasing proportion over time (p = 0.001). Their median onset...
Source: Journal of Neurology - July 15, 2017 Category: Neurology Source Type: research

Mortality after primary intracerebral hemorrhage in relation to post-stroke seizures
This study aims to determine the relation between seizures (i.e., with and without anti-epileptic therapy) and long-term mortality risk in a large patient population with intracerebral hemorrhage. We retrospectively included patients with a non-traumatic ICH in all three hospitals in the South Limburg region in the Netherlands between January 1st 2004 and December 31st 2009, and we assessed all-cause mortality until March 14th 2016. Patient who did not survive the first seven days after intracerebral hemorrhage were excluded from analyses. We used Cox multivariate analyses to determine independent predictors of mortality. ...
Source: Journal of Neurology - July 25, 2017 Category: Neurology Source Type: research

Hospital treatment costs and length of stay associated with hypertension and multimorbidity after hemorrhagic stroke
Previous studies have identified various treatment and patient characteristics that may be associated with higher hospital cost after spontaneous intracerebral hemorrhage (ICH); a devastating type of stroke. P...
Source: BMC Neurology - August 10, 2017 Category: Neurology Authors: Adrian V. Specogna, Tanvir C. Turin, Scott B. Patten and Michael D. Hill Tags: Research article Source Type: research

Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Background and Purpose—To identify predictors of in-hospital mortality in patients with aneurysmal subarachnoid hemorrhage and to estimate their impact.Methods—Retrospective analysis of prospective data from a nationwide multicenter registry on all aneurysmal subarachnoid hemorrhage cases admitted to a tertiary neurosurgical department in Switzerland (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]; 2009–2015). Both clinical and radiological independent predictors of in-hospital mortality were identified, and their effect size was determined by calculating adjusted odds ratios (aORs) using multivariate ...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Martin Nikolaus Stienen, Menno Germans, Jan–Karl Burkhardt, Marian C. Neidert, Christian Fung, David Bervini, Daniel Zumofen, Michel Rothlisberger, Serge Marbacher, Rodolfo Maduri, Thomas Robert, Martin A. Seule, Philippe Biȷlenga, Karl Schal Tags: Mortality/Survival, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Comments on “Short-Term Outcome of Spontaneous Intracerebral Hemorrhage in Algarve, Portugal: Retrospective Hospital-Based Study”
We were interested to read the paper by Nzwalo et al that was published in the Journal of Stroke and Cerebrovascular Diseases in 2018.1 The study was conducted to determine the predictors of 30-day in-hospital spontaneous intracerebral hemorrhage mortality in Algarve, the southernmost region of Portugal. It is clear that an interesting study has been conducted, but some methodological issues need to be taken into account.
Source: Journal of Stroke and Cerebrovascular Diseases - February 6, 2018 Category: Neurology Authors: Saeid Safiri, Ahad Ashrafi-Asgarabad Tags: Letter to the Editor Source Type: research

Prognosis comparisons in acute ischemic stroke patients with thrombolysis and nonthrombolysis therapy: a retrospective study with larger sample size
We compared the short-term, middle-term and long-term primary outcomes between thrombolysis and nonthrombolysis therapy in acute ischemic stroke (AIS) patients. Medical records were collected from patients suffered from AIS between 2010 and 2013 and allocated into either the intravenous recombinant tissue plasminogen activator (as rt-PA group) treatment, or non-rt-PA treatment group (as control group). The primary outcomes included a proportion of patients with favorable outcome [as defined with a modified Rankin Scale (mRS) of 0–1], functional independence (mRS of 0–2) or with bad outcome (mRS of 5–6) at 3, 6 and 12...
Source: Blood Coagulation and Fibrinolysis - February 9, 2018 Category: Hematology Tags: Original Articles Source Type: research

Response to Commentary on “Short-Term Outcome of Spontaneous Intracerebral Hemorrhage in Algarve, Portugal: Retrospective Hospital-Based Study”
We appreciate the correspondence by Safiri and Ashrafi-Asgarabad regarding our article “Short-Term Outcome of Spontaneous Intracerebral Hemorrhage in Algarve, Portugal: Retrospective Hospital-Based Study” recently published in Journal of Stroke and Cerebrovascular Diseases.1 It appears as if the methods and objectives of our study were misinterpreted. The main objective was to ide ntify the 30-day in-hospital predictors of death based on demographic, clinical, and radiological variables and for that, multivariate analysis was performed.
Source: Journal of Stroke and Cerebrovascular Diseases - March 19, 2018 Category: Neurology Authors: Hipolito Nzwalo, Ana Marreiros, Nicola Logallo Tags: Letter to the Editor Source Type: research

Dangers of outpatient nimodipine use after spontaneous subarachnoid hemorrhage in accordance with the Comprehensive Stroke Center guidelines
This report underscores the danger of outpatient nimodipine use and questions the optimal length of nimodipine therapy, especially in patients with low risk of vasospasm. Future studies, including randomized controlled trials and cost-effectiveness studies, are necessary to clarify the benefit of 21-day nimodipine therapy compared to a shortened duration of nimodipine.
Source: Journal of Clinical Neuroscience - April 12, 2018 Category: Neuroscience Source Type: research

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