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Condition: Hemorrhagic Stroke
Countries: Japan Health
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Total 300 results found since Jan 2013.
Development of Biomembrane-mimetic Nanoparticles for the Treatment of Ischemic Stroke
Yakugaku Zasshi. 2021;141(9):1071-1078. doi: 10.1248/yakushi.21-00114.ABSTRACTIncrease in vascular permeability of the blood-brain barrier (BBB) is a distinct pathology following ischemic stroke. In previous studies, we demonstrated that liposomal drug delivery system (DDS)-based delivery of neuroprotectants is useful for treating cerebral ischemia/reperfusion injury. Additionally, our previous studies reported that combination therapy with liposomal fasudil plus tissue plasminogen activator (t-PA), a thrombolytic agent, brings about decrease in the risk of t-PA-derived cerebral hemorrhage and prolong the therapeutic time ...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - September 2, 2021 Category: Drugs & Pharmacology Authors: Tatsuya Fukuta Source Type: research
Seasonal Variation in Incidence of Stroke in a General Population of 1.4 Million Japanese: The Shiga Stroke Registry
Conclusion: In the present large-scale stroke registry of general population, incidence rates of stroke were highest in winter and lowest in summer in current Japan.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 27, 2021 Category: Neurology Source Type: research
Impact of Physician Volume and Specialty on In-Hospital Mortality of Ischemic and Hemorrhagic Stroke
CONCLUSIONS: An increased number of stroke care physicians was associated with reduced in-hospital mortality for all types of stroke. The volume threshold of board-certified physicians depends on the specialty and stroke type.PMID:34393151 | DOI:10.1253/circj.CJ-20-1214
Source: Circulation Journal - August 16, 2021 Category: Cardiology Authors: Kunihiro Nishimura Kuniaki Ogasawara Takanari Kitazono Koji Iihara J-ASPECT Study Collaborators Source Type: research
Development of Machine Learning Models to Predict Probabilities and Types of Stroke at Prehospital Stage: the Japan Urgent Stroke Triage Score Using Machine Learning (JUST-ML)
AbstractIn conjunction with recent advancements in machine learning (ML), such technologies have been applied in various fields owing to their high predictive performance. We tried to develop prehospital stroke scale with ML. We conducted multi-center retrospective and prospective cohort study. The training cohort had eight centers in Japan from June 2015 to March 2018, and the test cohort had 13 centers from April 2019 to March 2020. We use the three different ML algorithms (logistic regression, random forests, XGBoost) to develop models. Main outcomes were large vessel occlusion (LVO), intracranial hemorrhage (ICH), suba...
Source: Translational Stroke Research - August 14, 2021 Category: Neurology Source Type: research
Hypertensive cerebral hemorrhage with undetectable plasma vascular endothelial growth factor levels in a patient receiving intravitreal injection of aflibercept for bilateral diabetic macular edema: a case report
ConclusionThis case suggests that hypertension and resultant cerebral hemorrhage can occur in patients with diabetic macular edema when plasma vascular endothelial growth factor levels are systemically decreased below the detection limit for a prolonged time after local injections of anti-vascular endothelial growth factor agents into the vitreous cavity. Therefore, severely reduced plasma vascular endothelial growth factor levels could be a higher risk factor to develop generally infrequent stroke. Ophthalmologists should be aware of possible severe reduction of plasma vascular endothelial growth factor levels and resulta...
Source: Journal of Medical Case Reports - July 27, 2021 Category: General Medicine Source Type: research
Non-alcoholic beverages intake and risk of cardiovascular disease among Japanese men and women: the JPHC study
In conclusion, the risks of stroke and total cardiovascular disease were lower with a higher intake of non-alcoholic beverages in Japanese men and women.PMID:34284829 | DOI:10.1017/S0007114521002737
Source: The British Journal of Nutrition - July 21, 2021 Category: Nutrition Authors: Renzhe Cui Hiroyasu Iso Ehab S Eshak Koutatsu Maruyama Junko Ishihara Ribeka Takachi Norie Sawada Shoichiro Tsugane JPHC Study Group Source Type: research
The Association between Adult Height and Stroke Incidence in Japanese Men and Women: A Population- Based Case- Control Study
CONCLUSIONS: We reported the associations between adult height and ischemic stroke subtypes for the first time, which differed according to sex and age-group.PMID:34176853 | DOI:10.2188/jea.JE20200531
Source: Journal of Epidemiology - June 28, 2021 Category: Epidemiology Authors: Yoshinobu Kondo Hiroshi Yatsuya Atsuhiko Ota Shoji Matsumoto Akihiro Ueda Hirohisa Watanabe Hideaki Toyoshima Source Type: research
