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Condition: Obesity
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Total 27 results found since Jan 2013.

China stroke surveillance report 2021
AbstractSince 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6 –18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survi...
Source: Military Medical Research - July 19, 2023 Category: International Medicine & Public Health Source Type: research

Molecular Mechanisms of Lipid-Based Metabolic Adaptation Strategies in Response to Cold
Cells. 2023 May 10;12(10):1353. doi: 10.3390/cells12101353.ABSTRACTTemperature changes and periods of detrimental cold occur frequently for many organisms in their natural habitats. Homeothermic animals have evolved metabolic adaptation strategies to increase mitochondrial-based energy expenditure and heat production, largely relying on fat as a fuel source. Alternatively, certain species are able to repress their metabolism during cold periods and enter a state of decreased physiological activity known as torpor. By contrast, poikilotherms, which are unable to maintain their internal temperature, predominantly increase me...
Source: Cancer Control - July 6, 2023 Category: Cancer & Oncology Authors: Gang Wu Ralf Baumeister Thomas Heimbucher Source Type: research

Pyruvate Kinase M2: a novel regulator of adipogenesis
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7944.ABSTRACTObesity is the cornerstone of many other conditions, with far-reaching impacts on numerous body systems and quality of life. Obesity is closely and likely causally associated with metabolic syndrome and consequent atherosclerosis, heart disease, stroke, and type 2 diabetes as well as diseases such as cancer and osteoarthritis. Recent studies suggest exploring the possibility of activating brown adipose tissue as a potential anti-obesity strategy. However, understanding the mechanisms underlying the processes of brown adipogenesis and browning is fou...
Source: Atherosclerosis - May 13, 2022 Category: Cardiology Authors: Presley D Dowker Jenna B Demeter Ahmed Bettaieb Source Type: research

Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism
Front Cardiovasc Med. 2021 Nov 23;8:768481. doi: 10.3389/fcvm.2021.768481. eCollection 2021.ABSTRACTHigh-fat Western diets contribute to tissue dysregulation of fatty acid and glucose intake, resulting in obesity and insulin resistance and their sequelae, including atherosclerosis. New therapies are desperately needed to interrupt this epidemic. The significant idea driving this research is that the understudied regulation of fatty acid entry into tissues at the endothelial cell (EC) interface can provide novel therapeutic targets that will greatly modify health outcomes and advance health-related knowledge. Dysfunctional ...
Source: Atherosclerosis - December 10, 2021 Category: Cardiology Authors: Umar R Rekhi Mohamed Omar Maria Alexiou Cole Delyea Linnet Immaraj Shokrollah Elahi Maria Febbraio Source Type: research

New Peptides as Potential Players in the Crosstalk Between the Brain and Obesity, Metabolic and Cardiovascular Diseases
According to the World Health Organization report published in 2016, 650 million people worldwide suffer from obesity, almost three times more than in 1975. Obesity is defined as excessive fat accumulation which may impair health with non-communicable diseases such as diabetes, cardiovascular diseases (hypertension, coronary artery disease, stroke), and some cancers. Despite medical advances, cardiovascular complications are still the leading causes of death arising from obesity. Excessive fat accumulation is caused by the imbalance between energy intake and expenditure. The pathogenesis of this process is complex and not ...
Source: Frontiers in Physiology - August 23, 2021 Category: Physiology Source Type: research

Tackling diabetes: how nurses can make the difference.
Authors: El Berri H, Gedik FG, Belkhadir J, Catton H, Hammerich A, Oweis A, Slama S Abstract This year, World Diabetes Day on 14 November coincides with the International Year of the Nurse and the Midwife, and therefore focuses on highlighting the role of nurses in the prevention and management of diabetes. Diabetes is recognized as an important cause of premature death and disability globally and in the Eastern Mediterranean Region, where its prevalence has been steadily increasing since 1990. Although the annual decline of the risk of dying from a major noncommunicable disease between the ages of 30 and 70 ye...
Source: Eastern Mediterranean Health Journal - November 24, 2020 Category: Middle East Health Tags: East Mediterr Health J Source Type: research

Prevalence and predictors of post-stroke epilepsy among Ghanaian stroke survivors
Post-stroke epilepsy (PSE) is associated with poorer quality of life, higher mortality, and greater health expenditures. We are unaware of any published reports on the frequency of and factors associated with PSE in Africa.
Source: Journal of the Neurological Sciences - September 10, 2020 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Vida Obese, Sheila Adamu, Manolo Agbenorku, Bruce Ovbiagele Source Type: research

Bariatric surgery reduces incidence of atrial fibrillation: a propensity score –matched analysis
Atrial fibrillation (AF) affects 33.5 million individuals worldwide [1] and it is estimated that the prevalence of AF in the United States will increase 2- to 3-fold over the next 50 years [2]. Patients with AF are more likely to experience a variety of negative health outcomes, including myocardial infarction, heart failure, and stroke [3,4]. In addition to these major health risks, there is a significant economic burden associated with AF, amounting to as much as $26 billion in annual healthcare expenditures in the United States alone [5].
Source: Surgery for Obesity and Related Diseases - November 24, 2018 Category: Surgery Authors: Kevin T. Lynch, J. Hunter Mehaffey, Robert B. Hawkins, Taryn E. Hassinger, Peter T. Hallowell, Jennifer L. Kirby Tags: Original article Source Type: research

Probiotics improve gut microbiota dysbiosis in obese mice fed a high-fat or high-sucrose diet
The prevalence of obesity has been dramatically increasing globally over decades [1]. Obesity is caused by a complex interaction of genetic and environmental factors, and is also suggested to be the result of a long-term imbalance between energy intake and expenditure [2]. Calorie-rich foods that are high in fat or carbohydrates combining with sedentary lifestyles are the most common factors underlying the global obesity epidemic [3]. High-fat diets (HFD) increase adipose tissue and induce metabolic and cardiovascular disorders (such as atherosclerosis, type 2 diabetes, stroke, and hypertension [4, 5]), especially in those...
Source: Nutrition - October 10, 2018 Category: Nutrition Authors: Cheng Kong, Renyuan Gao, Xuebing Yan, Linsheng Huang, Huanlong Qin Source Type: research

Magnolol promotes thermogenesis and attenuates oxidative stress in 3T3-L1 adipocytes
Obesity incidence is increasing worldwide at an alarming pace and has become a major threat to public health [1]. Indeed, obesity facilitates the development of hypertension, diabetes, stroke, osteoarthritis, and cancer [2,3]. It is well accepted that obesity results from an imbalance between energy expenditure and energy consumption, which causes excess energy storage in the form of lipids in white adipose tissue (WAT). Methods that either increase energy expenditure or reduce energy consumption are potential antiobesity strategies [4].
Source: Nutrition - February 5, 2018 Category: Nutrition Authors: Hilal Ahmad Parray, Jameel Lone, Jong Pil Park, Jang Won Choi, Jong Won Yun Tags: Basic nutritional investigation Source Type: research

A review on irisin, a new protagonist that mediates muscle-adipose-bone-neuron connectivity.
This study presents irisin as a new champion of the molecule, which could be considered as the messenger in the muscle-fat-bone-brain axis. PMID: 29131244 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - November 14, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Overfed and Underfed: Global Food Extremes
The international community of nations has made commitments to eliminate hunger, achieve food security and improved nutrition by 2030 and also to promote and protect health through nutritious diet, healthy eating and increased physical activity. Credit: IPSBy Joseph ChamieNEW YORK, Jun 12 2017 (IPS)Global food extremes of chronic undernourishment and obesity have brought about a bipolar world of hundreds of millions of underfed and overfed people. Of the world’s population of 7.5 billion the proportions suffering from chronic undernourishment and those afflicted by obesity are similar, approximately 11 percent or togethe...
Source: IPS Inter Press Service - Health - June 12, 2017 Category: International Medicine & Public Health Authors: Joseph Chamie Tags: Development & Aid Food & Agriculture Global Headlines Health Poverty & SDGs Regional Categories Source Type: news

Cardiovascular Drift during Training for Fitness in Patients with Metabolic Syndrome
Purpose: The health benefits of a training program are largely influenced by the exercise dose and intensity. We sought to determine whether during a training bout of continuous versus interval exercise the workload needs to be reduced to maintain the prescribed target heart rate (HR). Methods: Fourteen obese (31 ± 4 kg·m−2) middle-age (57 ± 8 yr) individuals with metabolic syndrome, underwent two exercise training bouts matched by energy expenditure (i.e., 70 ± 5 min of continuous exercise [CE] or 45 min of interval exercise, high-intensity interval training [HIIT]). All subjects completed both trials in a randomiz...
Source: Medicine and Science in Sports and Exercise - February 18, 2017 Category: Sports Medicine Tags: Applied Sciences Source Type: research

A Perfect Match: health, Hippocrates and lifestyle medicine
Amid the frustration and despair associated with rising premiums, healthcare costs and obesity prevalence, is a trend that is slowly infiltrating the healthcare industry. Although some of the most notable trends (in fitness and nutrition) tend to come and go as quickly as a fastball (World Series, anyone?), this particular trend has an immense amount of staying power based on current scientific research. This immense power has little to do with pharmacological interventions and prescription refills and much more to do with our feet, forks, fingers and minds. This trend, as written in a recent article by the influential and...
Source: Healthy Living - The Huffington Post - November 3, 2016 Category: Consumer Health News Source Type: news